公开(公告)号：US08798347B2

公开(公告)日：2014-08-05

申请号：US13045624

申请日：2011-03-11

申请人： Ying Zhu ,  Yanghai Tsin ,  Hari Sundar ,  Frank Sauer

发明人： Ying Zhu ,  Yanghai Tsin ,  Hari Sundar ,  Frank Sauer

IPC分类号： G06K9/00 ,  G06T7/20

CPC分类号： G06T7/204 ,  G06T7/248 ,  G06T2207/10121 ,  G06T2207/30048

摘要： A method for compensating respiratory motion in coronary fluoroscopic images includes finding a set of transformation parameters of a parametric motion model that maximize an objective function that is a weighted normalized cross correlation function of a reference image acquired at a first time that is warped by the parametric motion model and a first incoming image acquired at a second time subsequent to the first time. The weights are calculated as a ratio of a covariance of the gradients of the reference image and the gradients of the first incoming image with respect to a root of a product of a variance of the gradients of the reference image and the variance of the gradients of the first incoming image. The parametric motion model transforms the reference image to match the first incoming image.

摘要翻译： 用于补偿冠状动脉荧光镜图像中的呼吸运动的方法包括找到最大化目标函数的参数运动模型的一组变换参数，所述目标函数是在被参数化的第一时间获取的参考图像的加权归一化互相关函数 运动模型和在第一次之后的第二时间获取的第一输入图像。 权重被计算为参考图像的梯度和第一输入图像的梯度相对于参考图像的梯度的方差的乘积的根的梯度的梯度和协方差的梯度的方差的比率 第一个传入图像。 参数运动模型转换参考图像以匹配第一个输入图像。

公开(公告)号：US20130301897A1

公开(公告)日：2013-11-14

申请号：US13469311

申请日：2012-05-11

申请人： Ying Zhu ,  Liping Zhou

发明人： Ying Zhu ,  Liping Zhou

IPC分类号： G06K9/40 ,  G06K9/32

CPC分类号： G06T3/0068 ,  G06K9/6207 ,  G06T5/50 ,  G06T7/33 ,  G06T2207/10016 ,  G06T2207/10121 ,  G06T2207/30021 ,  G06T2207/30048 ,  G06T2207/30101 ,  G06T2207/30204

摘要： A method (100) that provides image processing of X-ray images that is particularly effective for the alignment of stent images and that, ultimately, provides stent image quality enhancement.

摘要翻译： 提供对支架图像的对准特别有效的X射线图像的图像处理的方法（100），并且最终提供支架图像质量增强。

公开(公告)号：US08515146B2

公开(公告)日：2013-08-20

申请号：US13277312

申请日：2011-10-20

申请人： Ying Zhu ,  Christophe Chefd'hotel

发明人： Ying Zhu ,  Christophe Chefd'hotel

IPC分类号： G06K9/00 ,  A61B1/00

CPC分类号： G06T5/006 ,  G06T7/194 ,  G06T2207/10081 ,  G06T2207/10121 ,  G06T2207/10132 ,  G06T2207/30021 ,  G06T2207/30101 ,  G06T2207/30204

摘要： A method for enhancing stent visibility includes acquiring a set of image frames including multiple test frames. A set of measurement points uniformly distributed within an image of a stent is defined in the test frames. A local image context is defined around each measurement point. A non-rigid deformation field relating the local image contexts of the test frames to local image contexts of a reference image is calculated. The non-rigid deformation field is optimized by maximizing a similarity function between the local image contexts of the test frames and the local image contexts of the reference image. The optimized non-rigid deformation field is used to deform images of a stent in the multiple test frames and combine the non-rigidly deformed images of the stent from the test frames. An image frame with the combined image of the stents superimposed thereon is displayed.

摘要翻译： 一种用于增强支架可见度的方法包括获取包括多个测试框架的一组图像帧。 在测试框架中定义了在支架的图像内均匀分布的一组测量点。 在每个测量点周围定义局部图像上下文。 计算将测试帧的局部图像上下文与参考图像的局部图像上下文相关联的非刚性变形场。 通过最大化测试帧的局部图像上下文与参考图像的局部图像上下文之间的相似度函数来优化非刚性变形场。 优化的非刚性变形场用于在多个测试框架中变形支架的图像，并将来自测试框架的支架的非刚性变形图像组合。 显示具有叠加在其上的支架的组合图像的图像帧。

公开(公告)号：US20120321169A1

公开(公告)日：2012-12-20

申请号：US13456542

申请日：2012-05-30

申请人： Sajjad Hussain Baloch ,  Erkang Cheng ,  Tong Fang ,  Ying Zhu

发明人： Sajjad Hussain Baloch ,  Erkang Cheng ,  Tong Fang ,  Ying Zhu

IPC分类号： G06K9/34

CPC分类号： G06T7/0083 ,  G06K9/4638 ,  G06K9/468 ,  G06K2209/05 ,  G06T7/12 ,  G06T7/143 ,  G06T7/149 ,  G06T2207/10072 ,  G06T2207/20076 ,  G06T2207/20124 ,  G06T2207/30101

摘要： A method for segmenting intracranial aneurysms in digital medical images includes extracting a mesh representing a vessel surface from a volumetric digital image, the mesh comprising a set of points {pi} and edges {eij} respective points, and finding a set of binary labelings that minimizes an energy functional of the labelings and of shape descriptors of each point in the mesh, where the binary labelings segments an aneurysm from the surface by associating one of two labels with each point pi, where a label indicates whether an associated point is on a vessel or on an aneurysm, where the energy functional includes a unary potential term summed over all points that represent a posterior distribution of the labels over the points, and a pairwise potential term summed over all edges that represents neighborhood labeling relationships.

摘要翻译： 用于在数字医学图像中分割颅内动脉瘤的方法包括从体积数字图像中提取表示血管表面的网格，所述网格包括一组点{pi}和边缘{eij}各自的点，并且找到一组二进制标记， 最小化网格中每个点的标签和形状描述符的能量功能，其中二进制标签通过将两个标签中的一个与每个点pi相关联来从表面分割动脉瘤，其中标签指示关联点是否在 血管或动脉瘤，其中能量功能包括表示标记在点上的后验分布的所有点上的一元潜在项，以及表示邻域标记关系的所有边缘上的成对潜在项。

公开(公告)号：US20120030835A1

公开(公告)日：2012-02-02

申请号：US13140779

申请日：2009-12-21

申请人： Jian Hua ,  Ying Zhu

发明人： Jian Hua ,  Ying Zhu

IPC分类号： C12N15/82 ,  C12N5/10 ,  A01H5/00 ,  C12N15/29 ,  C12N15/63

CPC分类号： C07K14/415 ,  C12N15/8279

摘要： Disclosed are nucleic acid molecules which encode heat-stable plant resistance polypeptides having NB-LRR structural motifs, where the LRR domain includes a sub-domain which confers heat-stability to a plant defense response. The invention further involves transgenic plants and transformed host cells that express these nucleic acid molecules and exhibit enhanced disease resistance over a wide range of temperatures.

摘要翻译： 公开了编码具有NB-LRR结构基序的热稳定植物抗性多肽的核酸分子，其中LRR结构域包括赋予植物防御反应热稳定性的亚结构域。 本发明还涉及表达这些核酸分子的转基因植物和转化的宿主细胞，并且在宽的温度范围内表现出增强的抗病性。

公开(公告)号：US08098889B2

公开(公告)日：2012-01-17

申请号：US12014397

申请日：2008-01-15

申请人： Ying Zhu ,  Gregory Baratoff ,  Thorsten Köhler

发明人： Ying Zhu ,  Gregory Baratoff ,  Thorsten Köhler

IPC分类号： G06K9/00

CPC分类号： B60W40/02 ,  G06T7/246 ,  G06T2207/20016 ,  G06T2207/20076 ,  G06T2207/20081 ,  G06T2207/30252 ,  G08G1/16 ,  G08G1/166 ,  G08G1/167

摘要： A method for vehicle detection and tracking includes acquiring video data including a plurality of frames, comparing a first frame of the acquired video data against a set of one or more vehicle detectors to form vehicle hypotheses, pruning and verifying the vehicle hypotheses using a set of course-to-fine constraints to detect a vehicle, and tracking the detected vehicle within one or more subsequent frames of the acquired video data by fusing shape template matching with one or more vehicle detectors.

摘要翻译： 一种用于车辆检测和跟踪的方法包括获取包括多个帧的视频数据，将所获取的视频数据的第一帧与一组一个或多个车辆检测器进行比较，以形成车辆假设，使用一组 通过融合与一个或多个车辆检测器的形状模板匹配来跟踪所获取的视频数据的一个或多个后续帧中的检测到的车辆。

公开(公告)号：US08094903B2

公开(公告)日：2012-01-10

申请号：US12157837

申请日：2008-06-13

申请人： Ying Zhu ,  Wei Zhang ,  Adrian Barbu ,  Simone Prummer ,  Martin Ostermeier ,  Dorin Comaniciu

发明人： Ying Zhu ,  Wei Zhang ,  Adrian Barbu ,  Simone Prummer ,  Martin Ostermeier ,  Dorin Comaniciu

IPC分类号： G06K9/03

CPC分类号： A61B6/504 ,  A61B6/481 ,  G06T5/50 ,  G06T7/215 ,  G06T7/30 ,  G06T2207/10016 ,  G06T2207/10121 ,  G06T2207/30048 ,  G06T2207/30101

摘要： A method and system for extracting coronary vessels fluoroscopic image sequences using coronary digital subtraction angiography (DSA) are disclosed. A set of mask images of a coronary region is received, and a sequence of contrast images for the coronary region is received. For each contrast image, vessel regions are detected in the contrast image using learning-based vessel segment detection and a background region of the contrast image is determined based on the detected vessel regions. Background motion is estimated between one of the mask images and the background region of the contrast image, and the mask image is warped based on the estimated background motion to generate an estimated background layer. The estimated background layer is subtracted from the contrast image to extract a coronary vessel layer for the contrast image.

摘要翻译： 公开了使用冠状动脉数字减影血管造影（DSA）提取冠脉血管荧光镜图像序列的方法和系统。 接收冠状动脉区域的一组掩模图像，并且接收冠状动脉区域的对比度图像序列。 对于每个对比图像，使用基于学习的血管段检测在对比图像中检测血管区域，并且基于检测到的血管区域确定造影剂图像的背景区域。 在掩模图像之一和对比度图像的背景区域之间估计背景运动，并且基于所估计的背景运动来对掩模图像进行翘曲以生成估计的背景层。 从对比图像中减去估计的背景层，以提取对比度图像的冠状血管层。

公开(公告)号：US20090010512A1

公开(公告)日：2009-01-08

申请号：US12157837

申请日：2008-06-13

申请人： Ying Zhu ,  Wei Zhang ,  Adrian Barbu ,  Simone Prummer ,  Martin Ostermeier ,  Dorin Comaniciu

发明人： Ying Zhu ,  Wei Zhang ,  Adrian Barbu ,  Simone Prummer ,  Martin Ostermeier ,  Dorin Comaniciu

IPC分类号： H05G1/64 ,  G06K9/00

CPC分类号： A61B6/504 ,  A61B6/481 ,  G06T5/50 ,  G06T7/215 ,  G06T7/30 ,  G06T2207/10016 ,  G06T2207/10121 ,  G06T2207/30048 ,  G06T2207/30101

摘要： A method and system for extracting coronary vessels fluoroscopic image sequences using coronary digital subtraction angiography (DSA) are disclosed. A set of mask images of a coronary region is received, and a sequence of contrast images for the coronary region is received. For each contrast image, vessel regions are detected in the contrast image using learning-based vessel segment detection and a background region of the contrast image is determined based on the detected vessel regions. Background motion is estimated between one of the mask images and the background region of the contrast image, and the mask image is warped based on the estimated background motion to generate an estimated background layer. The estimated background layer is subtracted from the contrast image to extract a coronary vessel layer for the contrast image.

摘要翻译： 公开了使用冠状动脉数字减影血管造影（DSA）提取冠脉血管荧光镜图像序列的方法和系统。 接收冠状动脉区域的一组掩模图像，并且接收冠状动脉区域的对比度图像序列。 对于每个对比图像，使用基于学习的血管段检测在对比图像中检测血管区域，并且基于检测到的血管区域确定造影剂图像的背景区域。 在掩模图像之一和对比度图像的背景区域之间估计背景运动，并且基于所估计的背景运动来对掩模图像进行翘曲以生成估计的背景层。 从对比图像中减去估计的背景层，以提取对比度图像的冠状血管层。

公开(公告)号：US07469192B2

公开(公告)日：2008-12-23

申请号：US11485046

申请日：2006-07-11

申请人： Tri Thanh Khuong ,  Junwei Bao ,  Jeffrey A. Chard ,  Wei Liu ,  Ying Zhu ,  Sachin Deshpande ,  Pranav Sheth ,  Hong Qiu

发明人： Tri Thanh Khuong ,  Junwei Bao ,  Jeffrey A. Chard ,  Wei Liu ,  Ying Zhu ,  Sachin Deshpande ,  Pranav Sheth ,  Hong Qiu

IPC分类号： G06F19/00 ,  G01B11/00

CPC分类号： G01B11/24 ,  G01N21/4788 ,  G01N21/95607 ,  G01N2021/95615 ,  G03F7/70625

摘要： A system to process requests for wafer structure profile determination from optical metrology measurements off a plurality of structures formed on one or more wafer includes a diffraction signal processor, a diffraction signal distributor, and a plurality of profile search servers. The diffraction signal processor is configured to obtain a plurality of measured diffraction signals of the plurality of structures. The diffraction signal distributor is coupled to the diffraction signal processor. The diffraction signal processor is configured to transmit the plurality of measured diffraction signals to the diffraction signal distributor. The plurality of profile search servers is coupled to the diffraction signal distributor. The diffraction signal distributor is configured to distribute the plurality of measured diffraction signals to the plurality of profile search servers. The profile search servers are configured to process in parallel the plurality of measured diffraction signals to determine profiles of the plurality of structures corresponding to the plurality of measured diffraction signals.

摘要翻译： 包括衍射信号处理器，衍射信号分配器和多个轮廓搜索服务器，用于处理从一个或多个晶片上形成的多个结构的光学测量测量的晶圆结构轮廓确定的请求的系统。 衍射信号处理器被配置为获得多个结构的多个测量的衍射信号。 衍射信号分配器耦合到衍射信号处理器。 衍射信号处理器被配置为将多个测量的衍射信号传输到衍射信号分配器。 多个轮廓搜索服务器耦合到衍射信号分配器。 衍射信号分配器被配置为将多个测量的衍射信号分布到多个简档搜索服务器。 轮廓搜索服务器被配置为并行处理多个测量的衍射信号，以确定与多个测量的衍射信号相对应的多个结构的轮廓。

公开(公告)号：US20080275335A1

公开(公告)日：2008-11-06

申请号：US12150816

申请日：2008-05-01

申请人： Wei Zhang ,  Ying Zhu ,  Adrian Barbu ,  Richard Socher ,  Stefan Bohm ,  Peter Durlak ,  Dorin Comaniciu

发明人： Wei Zhang ,  Ying Zhu ,  Adrian Barbu ,  Richard Socher ,  Stefan Bohm ,  Peter Durlak ,  Dorin Comaniciu

IPC分类号： A61B5/05 ,  G06K9/00

CPC分类号： G06K9/3216 ,  A61B6/12 ,  A61B6/481 ,  A61B6/504 ,  G06K2009/00932 ,  G06K2209/05 ,  G06T7/12 ,  G06T2207/20044 ,  G06T2207/30101 ,  G06T2207/30172

摘要： A virtual map of vessels of interest in medical procedures, such as coronary angioplasty is created so that doses of contrasting agent given to a patient may be reduced. A position of a coronary guidewire is determined and locations of vessel boundaries are found. When the contrast agent has dissipated, virtual maps of the vessels are created as new images. The locations of the determined vessel boundaries are imported to a mapping system and an image obtained without using a contrast agent is modified based on the imported locations of vessel boundaries. This creates a virtual map of the vessels.

摘要翻译： 创建医疗程序感兴趣的血管的虚拟地图，例如冠状动脉血管成形术，以便减少给予患者的剂量的造影剂。 确定冠状导丝的位置并找到血管边界的位置。 当造影剂消散时，血管的虚拟地图被创建为新的图像。 确定的容器边界的位置被导入到映射系统，并且基于导入的容器边界的位置来修改不使用造影剂获得的图像。 这将创建一个血管的虚拟地图。