Sulfated derivative of Gastrodia elata polysaccharide, preparation method and antitumor use thereof
    1.
    发明授权
    Sulfated derivative of Gastrodia elata polysaccharide, preparation method and antitumor use thereof 有权
    天麻多糖的硫酸化衍生物,其制备方法和抗肿瘤用途

    公开(公告)号:US08440238B2

    公开(公告)日:2013-05-14

    申请号:US12998169

    申请日:2009-09-21

    申请人: Kan Ding Hong Qiu

    发明人: Kan Ding Hong Qiu

    IPC分类号: A61K36/00

    摘要: The present invention discloses a sulfated derivative of polysaccharide extracted from gastrodia elata BL., the preparation method thereof and the use thereof in preparing antineoplastic medicaments, wherein, the gastrodia elata polysaccharide has the following structure: wherein, x and y are each an integer, and x+y=16, “n” is and integer, and the mean molecular weight of the polysaccharide from gastrodia elata is estimated as 2.8×105, the specific rotation of the polysaccharide is +95° in a 0.5 mg/mL aqueous solution thereof; the sulfated position is mainly at 6-hydroxy of the gastrodia elata polysaccharide, with mean molecular weight of 6.5×104 and a specific rotation of +150.0° in a 0.5 mg/mL aqueous solution thereof. In vivo and in vitro experiments indicate that the sulfated derivative of gastrodia elata polysaccharide can inhibit the tumor growth by suppressing the expression of Id1 to inhibit angiogenesis, and therefore has an obvious antitumor activity, and shows almost nontoxicity to endothelial cells, thereby having a good prospect of being developed into antineoplastic medicaments.

    摘要翻译: 本发明公开了一种从天麻BL提取的多糖的硫酸化衍生物及其制备方法及其在制备抗肿瘤药物中的应用,其中天竺葵多糖具有以下结构:其中x和y各自为整数, 和x + y = 16,“n”为整数,来自天麻的多糖的平均分子量估计为2.8×10 5,在0.5mg / mL水溶液中多糖的比旋光度为+ 95° 的; 硫酸化位置主要是天麻多糖的6-羟基,其0.5mg / mL水溶液中的平均分子量为6.5×10 4,比旋光度为+ 150.0°。 体内和体外实验表明,天竺葵多糖的硫酸化衍生物可抑制Id1的表达抑制血管生成,从而具有明显的抗肿瘤活性,对内皮细胞几乎无毒性,从而具有良好的抑制作用 被发展成抗肿瘤药物的前景。

    Allocating processing units to processing clusters to generate simulated diffraction signals
    2.
    发明申请
    Allocating processing units to processing clusters to generate simulated diffraction signals 失效
    将处理单元分配到处理簇以产生模拟衍射信号

    公开(公告)号:US20080115140A1

    公开(公告)日:2008-05-15

    申请号:US11525793

    申请日:2006-09-22

    IPC分类号: G06F9/50

    CPC分类号: G06F9/505

    摘要: In allocating processing units, first and second requests for jobs are obtained. First and second numbers of processing units requested are determined. First and second numbers of available processing units are determined. When the first number of available processing units is non-zero, the first number of available number of processing units or the first number of processing units requested is assigned to a first processing cluster. A first processing unit in the first processing cluster is designated as a master node. When the second number of available processing units is non-zero, the second number of available number of processing units or the second number of processing units requested is assigned to a second processing cluster. The first processing unit in the second processing cluster is designated as a slave node. The first and second jobs are assigned to the first and second processing clusters, respectively.

    摘要翻译: 在分配处理单元时,获得第一和第二个作业请求。 确定请求的第一和第二数量的处理单元。 确定可用处理单元的第一和第二数量。 当第一数量的可用处理单元不为零时,将第一数量的可用处理单元数量或所请求的第一数量的处理单元分配给第一处理簇。 第一处理簇中的第一处理单元被指定为主节点。 当第二数量的可用处理单元是非零时,将第二数量的可用数量的处理单元或第二数量的处理单元分配给第二处理簇。 第二处理簇中的第一处理单元被指定为从节点。 第一和第二作业分别分配给第一和第二处理簇。

    Piezoelectric element and method of manufacturing same
    3.
    发明授权
    Piezoelectric element and method of manufacturing same 失效
    压电元件及其制造方法

    公开(公告)号:US06803702B2

    公开(公告)日:2004-10-12

    申请号:US10050586

    申请日:2002-01-18

    IPC分类号: H01L4108

    摘要: When a piezoelectric material is manufactured by hydrothermal method, the proper amount of lead contained in the piezoelectric film can be ensured and decreases in piezoelectric characteristics can be prevented. A method for manufacturing a piezoelectric material expressed by the formula ABO3, containing an element “a” as the element expressed by A above, and having a perovskite crystal structure, comprises a first step of producing an oxide containing an element “a′”, and a second step of producing a piezoelectric material by subjecting the oxide produced in the first step to a hydrothermal processing using an aqueous solution containing the element “a”, wherein the amount of the element “a”, contained in the piezoelectric material produced in the second step is increased over the amount of the element “a” contained in the oxide produced in the first step.

    摘要翻译: 当通过水热法制造压电材料时,可以确保压电膜中所含的适量的铅,并且可以防止压电特性的降低。 制备由式ABO3表示的压电材料的方法,其包含元素“a”作为上述A表示的元素,并且具有钙钛矿晶体结构,包括制备含有元素“a”的氧化物的第一步骤, 以及第二步骤,通过使用含有元素“a”的水溶液对第一步骤中产生的氧化物进行水热处理来制造压电材料,其中包含在压电材料中所含的元素“a”的量 第二步骤比第一步产生的氧化物中所含的元素“a”的量增加。

    Method for manufacturing piezoelectric luminous element
    4.
    发明授权
    Method for manufacturing piezoelectric luminous element 有权
    制造压电发光元件的方法

    公开(公告)号:US06571446B2

    公开(公告)日:2003-06-03

    申请号:US09916747

    申请日:2001-07-30

    IPC分类号: H04R1700

    摘要: A method for manufacturing a piezoelectric element is disclosed. The method includes the steps of forming a lower electrode over a substrate, forming a piezoelectric luminous film over the lower electrode, forming an upper electrode over the piezoelectric film, forming a pressure luminous layer for emitting light upon application of pressure on the upper electrode, and attaching a substrate to the pressure luminous layer—has been inserted as a new abstract.

    摘要翻译: 公开了一种制造压电元件的方法。 该方法包括以下步骤:在衬底上形成下电极,在下电极上形成压电发光膜,在压电膜上形成上电极,形成用于在上电极施加压力时发光的压力发光层, 并将基板附着到压力发光层 - 作为新的摘要插入。

    Piezoelectric actuator, ink-jet type recording head, manufacturing method therefor, and ink-jet printer
    6.
    发明授权
    Piezoelectric actuator, ink-jet type recording head, manufacturing method therefor, and ink-jet printer 有权
    压电致动器,喷墨式记录头,其制造方法和喷墨打印机

    公开(公告)号:US06419848B1

    公开(公告)日:2002-07-16

    申请号:US09518189

    申请日:2000-03-02

    IPC分类号: H01L4100

    摘要: A piezoelectric actuator, comprising a stacked structure consisting of a top electrode 5, a piezoelectric film 4, and a bottom electrode 3, wherein the piezoelectric film comprises a first group 42 of piezoelectric ceramic particles and a second group 43 of piezoelectric ceramic particles. A distinctive feature is that the particles constituting the first group of piezoelectric ceramic particles are larger than the jingo particles constituting the second group of piezoelectric ceramic particles, and the first group of piezoelectric ceramic particles and the second group of piezoelectric ceramic particles have mutually different compositions. The piezoelectric actuator can thus be manufactured by an application method in a low-temperature environment, and a thicker piezoelectric film can be obtained. In addition, a highly practical piezoelectric film can be provided by combining the advantages of a plurality of material types.

    摘要翻译: 一种压电致动器,包括由顶部电极5,压电膜4和底部电极3组成的堆叠结构,其中压电膜包括压电陶瓷颗粒的第一组42和压电陶瓷颗粒的第二组43。 其特征在于构成第一组压电陶瓷颗粒的颗粒大于构成第二组压电陶瓷颗粒的微型颗粒,并且第一组压电陶瓷颗粒和第二组压电陶瓷颗粒具有相互不同的组成 。 因此,压电致动器可以通过在低温环境中的施加方法制造,并且可以获得更厚的压电膜。 此外,通过组合多种材料的优点,可以提供高度实用的压电膜。

    Ink-jet recording head with piezoelectric device and method for
manufacturing the same
    8.
    发明授权
    Ink-jet recording head with piezoelectric device and method for manufacturing the same 失效
    具有压电装置的喷墨记录头及其制造方法

    公开(公告)号:US6142615A

    公开(公告)日:2000-11-07

    申请号:US47432

    申请日:1998-03-25

    摘要: A piezoelectric device for an ink jet print head that has a greater displacement at a low drive voltage. The ink-jet recording head includes a vibration plate, on which is mounted one or more piezoelectric devices that change the volumes of pressure chambers upon application of a voltage. The device is mounted at least on one face of a pressure chamber substrate that is to be filled with ink. Such piezoelectric device includes a second piezoelectric layer having a piezoelectric constant g of a constant value or higher; and a first piezoelectric layer having a dielectric constant of a specific value or higher. Since the piezoelectric constant d of the piezoelectric device correlates with the product of the largest piezoelectric constant g and the largest dielectric device of the piezoelectric devices, a piezoelectric constant d larger than in the conventional case, i.e., having a greater displacement, can be obtained.

    摘要翻译: 一种用于喷墨打印头的压电装置,其在低驱动电压下具有较大的位移。 喷墨记录头包括振动板,在该振动板上安装有一个或多个在施加电压时改变压力室体积的压电装置。 装置至少安装在待填充油墨的压力室基板的一个面上。 这种压电装置包括具有恒定值或更高的压电常数g的第二压电层; 以及具有特定值或更高的介电常数的第一压电层。 由于压电元件的压电常数d与压电元件的最大压电常数g和最大电介质器件的乘积相关,所以可以获得比常规情况下更大位移(即具有较大位移)的压电常数d 。

    Allocating processing units to generate simulated diffraction signals used in optical metrology
    9.
    发明申请
    Allocating processing units to generate simulated diffraction signals used in optical metrology 失效
    分配处理单元以产生光学计量学中使用的模拟衍射信号

    公开(公告)号:US20080027565A1

    公开(公告)日:2008-01-31

    申请号:US11493290

    申请日:2006-07-25

    IPC分类号: G05B15/00

    CPC分类号: G01B11/24 G01N21/4788

    摘要: In allocating processing units of a computer system to generate simulated diffraction signals used in optical metrology, a request for a job to generate simulated diffraction signals using multiple processing units is obtained. A number of processing units requested for the job to generate simulated diffraction signals is then determined. A number of available processing units is determined. When the number of processing units requested is greater than the number of available processing units, a number of processing units is assigned to generate the simulated diffraction signals that is less than the number of processing units requested.

    摘要翻译: 在分配计算机系统的处理单元以产生光学测量中使用的模拟衍射信号时,获得使用多个处理单元产生模拟衍射信号的工作请求。 然后确定要求工作产生模拟衍射信号的多个处理单元。 确定了许多可用的处理单元。 当所请求的处理单元的数量大于可用处理单元的数量时,分配多个处理单元以产生小于所请求的处理单元的数量的模拟衍射信号。

    Generating a profile model to characterize a structure to be examined using optical metrology
    10.
    发明申请
    Generating a profile model to characterize a structure to be examined using optical metrology 审中-公开
    使用光学计量产生轮廓模型来表征要检查的结构

    公开(公告)号:US20080013107A1

    公开(公告)日:2008-01-17

    申请号:US11484974

    申请日:2006-07-11

    IPC分类号: G01B11/14

    摘要: In generating a profile model to characterize a structure to be examined using optical metrology, a view canvas is displayed, with the profile model being generated displayed in the view canvas. A profile shape palette is displayed adjacent to the view canvas. A plurality of different profile shape primitives is displayed in the profile shape palette. Each profile shape primitive in the profile shape palette is defined by a set of profile parameters. When a user selects a profile shape primitive from the profile shape palette, drags the selected profile shape primitive from the profile shape palette, and drops the selected profile shape primitive into the view canvas, the selected profile shape primitive is incorporated into the profile model being generated and displayed in the view canvas.

    摘要翻译: 在生成轮廓模型以使用光学计量学来表征要检查的结构时,显示视图画布,其中生成的轮廓模型显示在视图画布中。 在视图画布附近显示一个轮廓形状调色板。 在轮廓形状调色板中显示多个不同的轮廓形状基元。 轮廓形状调色板中的每个轮廓形状基元由一组轮廓参数定义。 当用户从轮廓形状调色板中选择轮廓形状基元时,从轮廓形状调色板中拖动所选择的轮廓形状基元,并将所选择的轮廓形状基元拖放到视图画布中,将所选择的轮廓形状原语合并到轮廓模型中 生成并显示在视图画布中。