公开(公告)号：US07875718B2

公开(公告)日：2011-01-25

申请号：US11725372

申请日：2007-03-19

申请人： Craig Smith ,  Stuart Purcell ,  Lucy Waddell ,  Nicholas Hayes ,  Jarrod Ritchie ,  Scott Brian Halliday ,  Melville Mitchell ,  George Scott Wilson

发明人： Craig Smith ,  Stuart Purcell ,  Lucy Waddell ,  Nicholas Hayes ,  Jarrod Ritchie ,  Scott Brian Halliday ,  Melville Mitchell ,  George Scott Wilson

IPC分类号： C07D489/08 ,  C07D489/02

CPC分类号： C07D489/08 ,  C07D489/02

摘要： This invention relates to intermediates useful in the preparation of opiate alkaloids, particularly morphinane compounds. The invention also relates to processes for preparing such intermediates and to processes which utilise such intermediates in the synthesis of morphinane compounds.

摘要翻译： 本发明涉及可用于制备阿片生物碱，特别是吗啡烷化合物的中间体。 本发明还涉及制备这种中间体的方法以及在合成吗啡烷化合物中利用这种中间体的方法。

公开(公告)号：US07729076B2

公开(公告)日：2010-06-01

申请号：US11750918

申请日：2007-05-18

申请人： Craig Smith ,  Brian Rigney ,  Todd Franks ,  Xin H. Yang ,  Stan Shepherd ,  Bruce Liikanen

发明人： Craig Smith ,  Brian Rigney ,  Todd Franks ,  Xin H. Yang ,  Stan Shepherd ,  Bruce Liikanen

IPC分类号： G11B5/03

CPC分类号： G11B5/024

摘要： Embodiments of the present invention allow for media erasure. Various embodiments allow for controlling an actuator based on feedback signal measurements and disk phase to seek a head across a surface of a disk systematically for an erasure operation. Also, in various embodiments, a substantially repeatable seek motion of a head across a stroke may be determined, and launch points at which the head is launched over a disk in the seek motion for erasing at least a portion of the disk are determined based on disk phase.

摘要翻译： 本发明的实施例允许媒体擦除。 各种实施例允许基于反馈信号测量和磁盘相位来控制致动器，以系统地跨磁盘的表面寻找头以进行擦除操作。 此外，在各种实施例中，可以确定头部横跨笔划的基本上可重复的寻道运动，并且基于用于擦除盘的至少一部分的寻道运动中的磁头在磁盘上发射的发射点基于 磁盘相位。

公开(公告)号：US07559032B2

公开(公告)日：2009-07-07

申请号：US09976726

申请日：2001-10-12

申请人： Jason King ,  Craig Smith ,  Greg McKaskle ,  Andrew Dove

发明人： Jason King ,  Craig Smith ,  Greg McKaskle ,  Andrew Dove

IPC分类号： G06F3/048 ,  G06F9/44 ,  G06F17/50 ,  G06F9/45

CPC分类号： G06F9/542

摘要： A system and method for enabling a graphical program to receive and respond to programmatic events. The graphical program may include a graphical user interface having various user interface elements and a block diagram having a plurality of nodes indicating functionality of the graphical program. The graphical program may be configured to respond to one or more events. For each event, a portion of graphical source code may be operable to receive and respond to a respective event. The portion of graphical source code may be executable to perform a desired process or action in response to the respective event. In one embodiment, a sub-program node may be associated with each event. In another embodiment, an event structure node may be included in the block diagram, wherein the event structure node includes one or more sub-diagrams, each sub-diagram including graphical source code for responding to one or more events.

摘要翻译： 一种使图形程序能够接收和响应编程事件的系统和方法。 图形程序可以包括具有各种用户界面元素的图形用户界面和具有指示图形程序的功能的多个节点的框图。 图形程序可以被配置为响应一个或多个事件。 对于每个事件，图形源代码的一部分可以用于接收和响应相应的事件。 图形源代码的一部分可以被执行以响应于相应的事件来执行期望的过程或动作。 在一个实施例中，子程序节点可以与每个事件相关联。 在另一个实施例中，事件结构节点可以包括在框图中，其中事件结构节点包括一个或多个子图，每个子图包括用于响应一个或多个事件的图形源代码。

公开(公告)号：US20080011975A1

公开(公告)日：2008-01-17

申请号：US11766715

申请日：2007-06-21

申请人： Jeffrey Robison ,  Michael Luque ,  Craig Smith ,  Stephen Chipman

发明人： Jeffrey Robison ,  Michael Luque ,  Craig Smith ,  Stephen Chipman

IPC分类号： F16K27/00

CPC分类号： F16K25/005 ,  F16K1/36

摘要： As set forth in the detailed description, the present invention includes, in various exemplary embodiments, a valve device to control fluid flow that incorporates a substantially flat plug head. By incorporating a substantially flat plug head, the valve device realizes lower stresses than other typical valve configurations; namely thermal and tensile stress is reduced throughout the valve device. In an exemplary embodiment of this invention, the valve device comprises a housing, at least one plug head seat within the housing, a substantially planar or flat plug head configured to control or stop flow of a substance and a plug stem configured to actuate the substantially flat plug head. In accordance with one exemplary embodiment, the substantially flat plug head comprises a solid disk shaped or cylindrical shaped plug head. Additionally, in one exemplary embodiment, the plug head and plug head seat material can comprise ceramics and various metal alloys.

摘要翻译： 如详细说明中所述，在各种示例性实施例中，本发明包括用于控制流体流动的阀装置，其包括基本上平坦的塞头。 通过结合基本平坦的塞头，阀装置实现比其它典型阀构造更低的应力; 即在整个阀装置中减少了热和拉应力。 在本发明的一个示例性实施例中，阀装置包括壳体，壳体内的至少一个塞头座，大致平面或扁平塞头，构造成控制或停止物质的流动，以及构造成致动基本上 扁头头 根据一个示例性实施例，基本上平坦的塞头包括实心盘形或圆柱形塞头。 另外，在一个示例性实施例中，插塞头和插头头座材料可以包括陶瓷和各种金属合金。

公开(公告)号：US20070268619A1

公开(公告)日：2007-11-22

申请号：US11750918

申请日：2007-05-18

申请人： Craig Smith ,  Brian Rigney ,  Todd Franks ,  Xin Yang ,  Stan Shepherd ,  Bruce Liikanen

发明人： Craig Smith ,  Brian Rigney ,  Todd Franks ,  Xin Yang ,  Stan Shepherd ,  Bruce Liikanen

IPC分类号： G11B5/596 ,  G11B5/03

CPC分类号： G11B5/024

摘要： Embodiments of the present invention allow for media erasure. Various embodiments allow for controlling an actuator based on feedback signal measurements and disk phase to seek a head across a surface of a disk systematically for an erasure operation. Also, in various embodiments, a substantially repeatable seek motion of a head across a stroke may be determined, and launch points at which the head is launched over a disk in the seek motion for erasing at least a portion of the disk are determined based on disk phase.

摘要翻译： 本发明的实施例允许媒体擦除。 各种实施例允许基于反馈信号测量和磁盘相位来控制致动器，以系统地跨磁盘的表面寻找头以进行擦除操作。 此外，在各种实施例中，可以确定头部横跨笔划的基本上可重复的寻道运动，并且基于用于擦除盘的至少一部分的寻道运动中的磁头在磁盘上发射的发射点基于 磁盘相位。

公开(公告)号：US20070242571A1

公开(公告)日：2007-10-18

申请号：US11736441

申请日：2007-04-17

申请人： Craig Smith ,  Bernhard Hiller ,  Stan Shepherd ,  Erhard Schreck

发明人： Craig Smith ,  Bernhard Hiller ,  Stan Shepherd ,  Erhard Schreck

IPC分类号： G11B7/085

CPC分类号： G11B21/12

摘要： Systems and methods from loading/unloading a data head for a disk drive provide for more efficient use of disk space. A method of loading/unloading a data head for a disk drive comprises determining a disk phase of a spinning disk arrangement, determining a loading/unloading position based on the disk phase, and loading or unloading the data head on or from, respectively, the spinning disk arrangement based on the determined disk phase. The determining a disk phase may be based on zero crossing of voltages for a three-phase motor associated with the spinning disk arrangement.

摘要翻译： 从磁盘驱动器加载/卸载数据头的系统和方法可以更有效地使用磁盘空间。 一种用于加载/卸载用于磁盘驱动器的数据头的方法包括确定旋转磁盘布置的磁盘相位，基于磁盘相位确定加载/卸载位置，以及分别在或从其分别加载或卸载数据磁头 基于确定的磁盘相位旋转磁盘布置。 确定盘相位可以基于与旋转盘装置相关联的三相电动机的电压的过零点。

公开(公告)号：US20070129403A1

公开(公告)日：2007-06-07

申请号：US11536808

申请日：2006-09-29

申请人： Craig Smith ,  David Rampe ,  Beth Borowsky ,  Sathapana Kongsamut

发明人： Craig Smith ,  David Rampe ,  Beth Borowsky ,  Sathapana Kongsamut

IPC分类号： A61K31/4439

CPC分类号： A61K31/4439

摘要： The present invention provides methods of treating schizophrenia and/or glucoregulatory abnormalities in a patient in need thereof comprising administering to said patient a therapeutically effective amount of a compound of formula I wherein in is 0, 1 or 2; n is 0, 1 or 2; p is 0 or 1; each R is independently hydrogen, halogen, trifluoromethyl, C1-C6alkyl, C1-C6alkoxy, benzyloxy, hydroxy, nitro or amino; each R1 is independently hydrogen, C1-C6alkyl, C1-C6alkenyl, C1-C6alkanoyl, halogen, cyano, —C(O)C1-C6alkyl, —C1-C6alkyleneCN, —C1-C6alkyleneNR′R″ wherein R′ and R″ are each independently hydrogen or C1-C6alkyl, —C1-C6alkyleneOC(O)C1-C6alkyl, or —CH(OH)R4 wherein R4 is hydrogen or C1-C6alkyl; R2 is hydrogen, C1-C6alkyl optionally substituted with halogen, hydroxy or benlzyloxy, C1-C6alkenyl, C1-C6alkynyl, —CO2C1-C6alkyl, or —R5—NR′R″ wherein R5 is C1-C6alkylene, C1-C6alkenylene or C1-C6alkynylene and R′ and R″ are each independently hydrogen, C1-C6alkyl or alternatively the group —NR′R″ as a whole is 1-pyrrolidinyl; and R3 is hydrogen, nitro, amino, halogen, C1-C6alkoxy, hydroxy or C1-C6alkyl or a pharmaceutically acceptable salt thereof.

公开(公告)号：US20060067934A1

公开(公告)日：2006-03-30

申请号：US11260192

申请日：2005-10-28

申请人： Craig Smith ,  Raymond Goodwin ,  M. Beckmann

发明人： Craig Smith ,  Raymond Goodwin ,  M. Beckmann

IPC分类号： A61K39/395 ,  C07K16/28

CPC分类号： G01N33/6863 ,  A61K38/00 ,  C07K14/7151 ,  G01N2333/525 ,  G01N2500/02 ,  G01N2800/26

摘要： Tumor necrosis factor receptor DNAs and expression vectors encoding TNF receptors, and processes for producing TNF receptors as products of recombinant cell culture, are disclosed.

摘要翻译： 公开了肿瘤坏死因子受体DNA和编码TNF受体的表达载体，以及作为重组细胞培养产物产生TNF受体的方法。

公开(公告)号：US20060013486A1

公开(公告)日：2006-01-19

申请号：US10890012

申请日：2004-07-13

申请人： Peter Burns ,  Donald Williams ,  Craig Smith ,  Robert Reisch

发明人： Peter Burns ,  Donald Williams ,  Craig Smith ,  Robert Reisch

IPC分类号： G06K9/46

CPC分类号： G06T7/001 ,  G06K9/00577 ,  G06K9/4642 ,  G06K2009/00583

摘要： In an identification method, an analysis region in a test digital image is identified and values of a test parameter at a grid of locations in the analysis region are determined. A reference model of fixed pattern noise is associated with the test image. The reference model has an array of values of the test parameter for fixed pattern noise of a reference image acquisition device. A two or more dimensional similarity measure is calculated between the grid and at least a corresponding portion of the array.

摘要翻译： 在识别方法中，识别测试数字图像中的分析区域，并且确定分析区域中位置网格处的测试参数的值。 固定模式噪声的参考模型与测试图像相关联。 参考模型具有参考图像采集装置的固定模式噪声的测试参数值的数组。 在网格和阵列的至少相应部分之间计算两个或更多个维度相似性度量。

公开(公告)号：US20050240581A1

公开(公告)日：2005-10-27

申请号：US10508398

申请日：2004-02-11

申请人： Craig Smith ,  Robert Richards

发明人： Craig Smith ,  Robert Richards

IPC分类号： A61J7/00 ,  A61J7/04 ,  G06K9/00 ,  G07C9/00 ,  G06F7/00

CPC分类号： G07C9/00158 ,  A61J7/0418 ,  A61J7/0427 ,  A61J7/0463 ,  G06F19/3456 ,  G06K9/00597 ,  G07F17/0092 ,  G16H10/60 ,  Y02A90/26

摘要： A computerised identity matching management process for the supply of a pharmaceutical substance to an authorised person. The process identifies a person who is requesting the supply of the substance which includes the steps of a management computer receiving a request, from capture apparatus waiting to commence a biometric capture process representative of the person to initiate the capture process. The management computer responds to the request to return a message to the capture apparatus at a first instant in time, the message containing a unique code, and receipt of the message containing the code at the capture apparatus causes initiation of the capture process. The management computer, after returning the message, receives a captured biometric representative of the person from the capture apparatus coded with the code, at a second instant in time. The management computer operates, when the second instant is less than a predetermined time later than the first instant, to decode the captured biometric and initiate a matching process to find a match for the decoded captured biometric against stored biometric records and to retrieve an identification code representative of the person when a match is found. The management computer retrieves a date stamp and uses the identification code to retrieve a data record of the person which includes at least a substance the person is prescribed, a quantity in which the substance is to be supplied and a date at which the substance is to be supplied and determines whether the date stamp matches the date at which the substance is to be supplied. If a match is determined, the substance is supplied in the prescribed quantity and information is recorded to form a record to update the supply of the substance to the person.

摘要翻译： 向授权人员提供药物的计算机身份匹配管理流程。 该过程识别正在请求提供物质的人，其包括接收请求的管理计算机的步骤，从捕获设备等待开始代表该人的生物识别捕获过程以启动捕获过程。 管理计算机响应于在第一时刻将消息返回到捕获设备的请求，包含唯一代码的消息以及在捕获设备处包含代码的消息的接收导致捕获过程的开始。 管理计算机在返回消息之后，在第二时刻从用来自代码编码的捕获装置接收被捕获的生物特征代表。 管理计算机在第二时刻小于第一时刻之后的预定时间时操作，以对所捕获的生物特征进行解码，并启动匹配处理以找到针对所存储的生物测定记录的经解码的捕获的生物特征的匹配，并且检索识别码 发现比赛的人的代表。 管理计算机检索日期戳，并使用识别代码检索该人的数据记录，该数据记录至少包括该物质被规定的物质，该物质将被提供的数量和该物质所在的日期 并确定日期戳是否与提供物质的日期相匹配。 如果确定比赛，则以规定数量提供物质，并记录信息以形成记录，以更新对该物质的物质供应。