公开(公告)号：US10709362B2

公开(公告)日：2020-07-14

申请号：US16691358

申请日：2019-11-21

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  James H. Brauker ,  Mark C. Brister ,  Paul V. Goode, Jr. ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Jack Pryor ,  Matthew D. Wightlin

IPC分类号： A61B5/1473 ,  A61B5/1495 ,  A61B5/1486 ,  A61B5/1468 ,  A61B5/145 ,  A61B5/00 ,  A61B5/15 ,  A61B5/05 ,  A61B17/34 ,  A61M5/172 ,  A61M5/158 ,  A61M5/142

摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20200100713A1

公开(公告)日：2020-04-02

申请号：US16691422

申请日：2019-11-21

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  Mark C. Brister ,  Matthew D. Wightlin

IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/1473 ,  A61B17/34 ,  A61B5/1486 ,  A61B5/05 ,  A61B5/15

摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20200037875A1

公开(公告)日：2020-02-06

申请号：US16599072

申请日：2019-10-10

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  Robert J. Boock ,  Mark C. Brister ,  Monica A. Rixman ,  Kum Ming Woo ,  Lisa Nguyen ,  Seth R. Brunner ,  Arthur Chee ,  Melissa A. Nicholas ,  Matthew D. Wightlin ,  Jack Pryor ,  Dubravka Markovic

IPC分类号： A61B5/00 ,  A61B5/1486 ,  A61B5/1473 ,  A61B5/145

摘要： Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

公开(公告)号：US20190339224A1

公开(公告)日：2019-11-07

申请号：US16402124

申请日：2019-05-02

申请人： DexCom, Inc.

发明人： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC分类号： G01N27/327

摘要： Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US20190339221A1

公开(公告)日：2019-11-07

申请号：US16402013

申请日：2019-05-02

申请人： DexCom, Inc.

发明人： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC分类号： G01N27/327

摘要： Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US20190335997A1

公开(公告)日：2019-11-07

申请号：US16453925

申请日：2019-06-26

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  Robert J. Boock ,  Mark C. Brister ,  Monica A. Rixman ,  Kum Ming Woo ,  Lisa Nguyen ,  Seth R. Brunner ,  Arthur Chee ,  Melissa A. Nicholas ,  Matthew D. Wightlin ,  Jack Pryor ,  Dubravka Markovic

IPC分类号： A61B5/00 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/1473

摘要： Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

公开(公告)号：US10420494B2

公开(公告)日：2019-09-24

申请号：US15877682

申请日：2018-01-23

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  Robert J. Boock ,  Apurv Ullas Kamath ,  Matthew D. Wightlin ,  Michael J. Estes

IPC分类号： A61B5/00 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/1486 ,  B05C3/10

摘要： Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 180 is provided having a first working electrode 150 comprising a first sensor element 102 and a second working electrode 160 comprising a second sensor element 104, and a reference electrode 108 for providing a reference value for measuring the working electrode potential of the sensor elements 102, 104.

公开(公告)号：US10314525B2

公开(公告)日：2019-06-11

申请号：US14590483

申请日：2015-01-06

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  Mark C. Brister ,  Matthew D. Wightlin

IPC分类号： A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  A61B17/34

摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US10028683B2

公开(公告)日：2018-07-24

申请号：US14508990

申请日：2014-10-07

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  Robert J. Boock ,  Matthew D. Wightlin ,  Mark C. Shults

IPC分类号： A61B5/05 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00

摘要： Systems and methods of use involving sensors having a particle-containing domain are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

公开(公告)号：US09517025B2

公开(公告)日：2016-12-13

申请号：US15153586

申请日：2016-05-12

申请人： DexCom, Inc.

发明人： Daiting Rong ,  Sebastian Böhm ,  Matthew D. Wightlin

IPC分类号： G01N33/483 ,  G01N33/50 ,  A61B5/1486 ,  A61B5/145

CPC分类号： A61B5/14532 ,  A61B5/14865 ,  A61B2560/0223 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/125

摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes an electrochemical sensor incorporating a silver/silver chloride reference electrode, wherein a capacity of the reference electrode is controlled.

摘要翻译： 提供了用于宿主血管系统的连续分析物测量的系统和方法。 在一些实施方案中，连续葡萄糖测量系统包括结合有银/氯化银参考电极的电化学传感器，其中控制参比电极的容量。