公开(公告)号：US20240358293A1

公开(公告)日：2024-10-31

申请号：US18639650

申请日：2024-04-18

Applicant: Abbott Diabetes Care Inc.

Inventor： Jonathan D. MCCANLESS ,  Benjamin J. FELDMAN ,  Udo HOSS

IPC: A61B5/1486 ,  A61B5/00 ,  A61L31/08 ,  A61L31/16

CPC classification number: A61B5/14865 ,  A61B5/6849 ,  A61L31/088 ,  A61L31/16 ,  A61B2562/125 ,  A61L2300/404

Abstract: The present disclosure provides analyte sensors comprising a sensor tail substrate having a lower portion and configured for insertion into a tissue; a first working electrode disposed on the lower portion of the sensor tail substrate; a first sensing layer disposed upon a surface of the first working electrode; and a membrane disposed over at least the sensing layer; wherein the membrane comprises 20% to 50% by weight of a silver salt. The present disclosure also provides methods of using such analyte sensors for detecting one or more analytes present in a biological sample and methods of manufacturing the analyte sensors.

公开(公告)号：US20240350170A1

公开(公告)日：2024-10-24

申请号：US18637185

申请日：2024-04-16

Applicant: Boston Scientific Medical Device Limited

Inventor： Lauren Koon

IPC: A61B17/34 ,  A61B5/283 ,  A61B5/367 ,  A61B17/00

CPC classification number: A61B17/3476 ,  A61B5/283 ,  A61B5/367 ,  A61B2017/00526 ,  A61B2562/125

Abstract: A medical device includes an elongate body including a proximal portion and a distal portion. The device includes an electrode located on the distal portion. A conductor extends from the electrode to the proximal portion. The electrode and the conductor are formed of a single piece of continuous material.

公开(公告)号：US20240341644A1

公开(公告)日：2024-10-17

申请号：US18754597

申请日：2024-06-26

Applicant: Allez Health Inc.

Inventor： Robert James Boock

IPC: A61B5/1486 ,  A61B5/145 ,  C12N9/04 ,  C12Q1/00 ,  C25D7/06 ,  C25D9/02 ,  G01N27/327 ,  H01M4/02 ,  H01M4/04 ,  H01M4/1395 ,  H01M4/1399 ,  H01M4/96

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  C12N9/0006 ,  C12Q1/002 ,  C12Q1/006 ,  C25D7/0607 ,  C25D9/02 ,  G01N27/3271 ,  G01N27/3275 ,  H01M4/02 ,  H01M4/0402 ,  H01M4/0419 ,  H01M4/045 ,  H01M4/1395 ,  H01M4/1399 ,  H01M4/96 ,  A61B2562/125 ,  C12Y101/01027 ,  C12Y101/0103 ,  C12Y101/03004 ,  H01M2004/024

Abstract: A conductive substrate for a working electrode for a biological sensor includes a plastic substrate comprising an organic polymer or a thermoplastic. A carbon compound is on the plastic substrate. The carbon compound includes an elastomeric material and a carbon material from an aqueous solution. The carbon compound includes at least two materials from a group of carbon black, graphene, pyrolytic carbon, pyrolytic graphite, and diamagnetic graphite. The conductive substrate receives and transfers free electrons generated by an enzyme in the working electrode.

公开(公告)号：US20240315614A1

公开(公告)日：2024-09-26

申请号：US18431808

申请日：2024-02-02

Applicant: Biolinq Incorporated

Inventor： Alan Steven CAMPBELL ,  Robert MCKINLAY ,  Anderson MICU ,  Shuai XU ,  Jacob CLARY

IPC: A61B5/145 ,  A61B5/00

CPC classification number: A61B5/14546 ,  A61B5/685 ,  A61B2562/125

Abstract: Described herein are variations of an analyte monitoring system, including an analyte monitoring device. For example, an analyte monitoring device may include an implantable microneedle array for use in measuring one or more analytes (e.g., glucose), such as in a continuous manner. Each microneedle of the microneedle array may include a microneedle body, an electrode material on the microneedle body, a biorecognition layer on the electrode material, a diffusion-limiting layer on the biorecognition layer, an interferent blocking agent, and/or an attachment enhancer between the biorecognition layer and the diffusion-limiting layer, where the interferent blocking agent and the attachment enhancer are configured to improve sensor sensitivity variability.

公开(公告)号：US12096553B2

公开(公告)日：2024-09-17

申请号：US16572652

申请日：2019-09-17

Applicant: CARNEGIE MELLON UNIVERSITY

Inventor： Gary K. Fedder ,  Carmel Majidi ,  Philip R. LeDuc ,  Lee E. Weiss ,  Christopher J. Bettinger ,  Naser Naserifar

IPC: H05K1/02 ,  B29C33/40 ,  H01L21/48 ,  H05K1/18 ,  H05K3/30 ,  H05K3/38 ,  H05K3/46 ,  B05D3/10 ,  H01L23/31 ,  H05K5/06

CPC classification number: H05K1/0283 ,  B29C33/40 ,  H01L21/4803 ,  H05K1/02 ,  H05K1/185 ,  H05K3/30 ,  H05K3/38 ,  H05K3/4644 ,  A61B2562/125 ,  A61B2562/164 ,  B05D3/10 ,  B05D3/107 ,  B05D3/108 ,  H01L23/3121 ,  H05K5/065 ,  H05K2201/1003

Abstract: A flexible and stretchable integrated electronic device includes a substrate having a stiffness gradient, wherein a rigid electronic device is embedded within the substrate. The stiffness gradient within the substrate prevents delamination at the interface between the substrate and the embedded device. The stiffness gradient is accomplished by providing at least two distinct zones in the substrate with uniform stiffness, with each zone decreasing in stiffness as in a distance from the embedded device increases, or the gradient is accomplished by having a zone with a varying stiffness.

公开(公告)号：US20240298941A1

公开(公告)日：2024-09-12

申请号：US18666596

申请日：2024-05-16

Applicant: Medtronic MiniMed, Inc.

Inventor： Ashwin K. Rao ,  Qingling Yang ,  Ellis Garai ,  Daniel E. Pesantez

IPC: A61B5/1486 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/7246 ,  A61B2562/125

Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

公开(公告)号：US12082942B2

公开(公告)日：2024-09-10

申请号：US15824814

申请日：2017-11-28

Applicant: INTERAXON INC.

Inventor： Christopher Allen Aimone ,  Trevor Coleman ,  Ariel Stephanie Garten ,  Samuel Thomas Mackenzie

IPC: A61B5/00 ,  A61B5/291

CPC classification number: A61B5/6803 ,  A61B5/291 ,  A61B5/6831 ,  A61B5/7203 ,  A61B5/6814 ,  A61B2562/0215 ,  A61B2562/125 ,  A61B2562/164 ,  A61B2562/166

Abstract: A wearable apparatus for wearing on a head of a user, the apparatus has a band assembly comprising an outer band member comprising outer band ends joined by a curved outer band portion of a curve generally shaped to correspond to the users forehead; a flexible inner band member comprising inner band ends joined by a curved inner band portion of a curve generally shaped to correspond to the user's forehead, the inner band member is attached to the outer band member at least by each inner band end respectively attached to a respective one of the outer band ends; at least one brainwave sensor disposed inwardly along the curved inner band portion to provide a flexible conductive surface; and a deformable attachment that connects the flexible inner band member to the outer band, the deformable attachment allowing the inner band to conform to the user's forehead shape, the deformable attachment having a biasing component to urge the at the at least one brainwave sensor towards the user's forehead when worn by the user.

公开(公告)号：US20240293064A1

公开(公告)日：2024-09-05

申请号：US18029497

申请日：2021-12-24

Applicant: SHIN-ETSU CHEMICAL CO., LTD.

Inventor： Jun HATAKEYAMA ,  Motoaki IWABUCHI ,  Joe IKEDA ,  Osamu WATANABE ,  Shiori NONAKA ,  Koji HASEGAWA

IPC: A61B5/259 ,  A61B5/265 ,  A61B5/268 ,  A61B5/28

CPC classification number: A61B5/259 ,  A61B5/265 ,  A61B5/268 ,  A61B5/28 ,  A61B2562/0215 ,  A61B2562/125 ,  A61B2562/164 ,  A61B2562/227

Abstract: A bio-electrode includes a porous, stretchy base material, an adhesive, conductive film containing silicon, and a conducting path. The conductive film is formed on one surface of the porous, stretchy base material. The conducting path is connected to the conductive film, and penetrates the stretchy base material to be exposed on the opposite side. This enables provision of the bio-electrode that has high sensitivity to a bio-signal and excellent bio-compatibility, that is lightweight, that can be produced at low cost, that is free of itching, red spots, and rash of the skin and comfortable even when being wet, dried, or attached to the skin for a long period of time, without a significant decrease in sensitivity to the bio-signal, a production method for the bio-electrode, and a measurement method for a bio-signal.

公开(公告)号：US12063749B2

公开(公告)日：2024-08-13

申请号：US17264957

申请日：2020-05-27

Applicant: BOE TECHNOLOGY GROUP CO., LTD.

Inventor： Fan Li ,  Jiangbo Chen

IPC: H05K3/20 ,  A61B5/263 ,  A61N1/04 ,  H05K1/03 ,  H05K1/09 ,  H05K1/11 ,  H05K3/00

CPC classification number: H05K3/20 ,  H05K1/09 ,  H05K1/118 ,  H05K3/0058 ,  A61B5/263 ,  A61B2562/125 ,  A61N1/04 ,  H05K1/0346 ,  H05K3/002 ,  H05K2201/0154 ,  H05K2201/0323 ,  H05K2201/0367 ,  H05K2203/0147

Abstract: The present application provides a method for manufacturing a microelectrode film. The method includes: forming at least one recess on the carrier substrate by isotropic etching; forming a microelectrode seed pattern in the recess; growing a microelectrode in the recess by using the microelectrode seed pattern; making a first substrate to be in contact with a side of the carrier substrate having the recess thereon; separating the microelectrode from the carrier substrate to transfer the microelectrode onto the first substrate.

公开(公告)号：US12048845B2

公开(公告)日：2024-07-30

申请号：US17824412

申请日：2022-05-25

Applicant: Teliatry, Inc.

Inventor： Rahul Saini

IPC: A61N1/375 ,  A61N1/36 ,  A61B5/00 ,  A61B5/24 ,  A61N1/05 ,  A61N1/372

CPC classification number: A61N1/36071 ,  A61N1/3605 ,  A61N1/375 ,  A61B5/24 ,  A61B5/686 ,  A61B5/6868 ,  A61B5/6877 ,  A61B2562/125 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/36053 ,  A61N1/36067 ,  A61N1/37288 ,  A61N1/3758

Abstract: Implantable devices are provided herein, along with methods of fabricated such implantable devices. An exemplary method of fabricating an implantable device includes coupling electronics to a conductive via at a first side of a first glass substrate. The conductive via extends from the first side through the first glass substrate to a second side of the first glass substrate. The method further includes attaching a second glass substrate to cap the first side of the first glass substrate and form a hermetically sealed chamber containing the electronics, rounding edges of the implantable device after attaching the cap.