公开(公告)号：US11040174B2

公开(公告)日：2021-06-22

申请号：US15813510

申请日：2017-11-15

Applicant: Edwards Lifesciences Corporation

Inventor： Bao Khuu ,  Matthew T. Winston ,  Asher L. Metchik ,  Eric Robert Dixon ,  Sergio Delgado

IPC: A61M25/01 ,  A61B1/005 ,  A61B17/00

Abstract: Disclosed herein are steerable catheter assemblies and methods of steering catheters. Some embodiments include a catheter with first and second oppositely disposed pull wires and third and fourth oppositely disposed pull wires that flex the catheter, a control handle coupled to the catheter, a first follower connected to the first pull wire, a second follower connected to the second pull wire, a first driver coupled to the control handle and coupled to the first and second followers, a third follower connected to the third pull wire, a fourth follower connected to the fourth pull wire, and a second driver coupled to the control handle and coupled to the third and fourth followers. Rotation of the first driver moves the first and second followers in opposite directions. Rotation of the second driver moves the third and fourth followers in opposite directions.

公开(公告)号：US11033387B2

公开(公告)日：2021-06-15

申请号：US16378307

申请日：2019-04-08

Applicant: Edwards Lifesciences Corporation

Inventor： John J. Desrosiers ,  Amanda Kristine Anderson White ,  Michael R. Bialas ,  Gilbert Madrid ,  Michael J. Popp ,  Thanh V. Nguyen ,  Jun Liu ,  Asher L. Metchik ,  Darshin S. Patel

IPC: A61F2/24

Abstract: One method of implanting a prosthetic valve includes advancing the valve into a patient with a delivery apparatus. The valve includes apices circumferentially-spaced apart relative to each other. At least some of the apices include first apertures. The delivery apparatus includes release arms and a sheath. The release arms include second apertures for receiving the apices. At least one of the second apertures of the release arms has a different length than another one of the second apertures. The method also includes positioning the valve at a location, retracting a sheath of the delivery apparatus relative to the valve, allowing the valve to self-expand from a radially compressed state to a radially expanded state, and while the valve is coupled to the delivery apparatus, pivoting the valve relative about the release arms such that an axis of the valve is tilted relative to an axis of the delivery apparatus.

公开(公告)号：US11026788B2

公开(公告)日：2021-06-08

申请号：US15238605

申请日：2016-08-16

Applicant: Edwards Lifesciences Corporation

Inventor： Asher L. Metchik ,  Thanh V. Nguyen ,  Raz Biran ,  Arvin T. Chang ,  Tarannum Nagpurwala ,  Jeff Lindstrom

IPC: A61F2/24 ,  A61F2/00 ,  A61F2/95

Abstract: A loader and method for loading a transcatheter heart valve into a delivery sheath or catheter is described that is also configured to facilitate retrieval of the heart valve back through the delivery sheath while protecting the delivery sheath from damage. Another loader provides for easier crimping and loading of a THV into a delivery sheath or catheter from a storage jar or container. A method for crimping a THV facilitates easier end user preparation of the valve for implantation and reduces the likelihood of tissue deformation in the valve during storage. These devices and methods for deploying THVs simplify the valve replacement procedure.

公开(公告)号：US10799677B2

公开(公告)日：2020-10-13

申请号：US15815385

申请日：2017-11-16

Applicant: Edwards Lifesciences Corporation

Inventor： Bao Khuu ,  Matthew T. Winston ,  Asher L. Metchik ,  Eric Robert Dixon

IPC: A61M25/01 ,  F16H37/12 ,  F16H19/04 ,  F16H25/16 ,  F16H19/06 ,  A61F2/24 ,  F16C11/06 ,  A61B17/00 ,  A61F2/95

Abstract: Disclosed herein are steerable catheter assemblies and methods of steering catheters that utilize gimbal plate and ring mechanisms to accomplish independent control of catheter flex magnitude and catheter flex direction. Some embodiments include a catheter with two or more pull wires that flex the catheter, a housing connected to the catheter, a gimbal ring pivotally connected to the housing, a gimbal plate pivotally connected to the gimbal ring to form a gimbal assembly, and an adjustment member coupled to the gimbal assembly, such that the adjustment member is movable axially and rotationally relative to the gimbal assembly. The two or more pull wires are connected to the gimbal plate, the adjustment member engages the gimbal plate such that movement of the adjustment member adjusts the position of the gimbal assembly to thereby flex the catheter with the pull wires.

公开(公告)号：US10799676B2

公开(公告)日：2020-10-13

申请号：US15815332

申请日：2017-11-16

Applicant: Edwards Lifesciences Corporation

Inventor： Bao Khuu ,  Matthew T. Winston ,  Asher L. Metchik ,  Eric Robert Dixon

IPC: A61M25/01 ,  F16C11/06 ,  F16H19/06 ,  F16H25/16 ,  F16H37/12 ,  A61F2/24 ,  A61F2/95

Abstract: Disclosed herein are steerable catheter assemblies and methods of steering catheters that utilize ball and socket mechanisms to accomplish independent control of catheter flex magnitude and catheter flex direction. Some embodiments include a catheter with two or more pull wires that flex the catheter, a first ball, a socket coupled to the first ball to form a ball and socket assembly, and an adjustment member coupled to the ball and socket assembly, such that the adjustment member is movable axially and rotationally relative to the ball and socket assembly. Two or more pull wires are connected to the socket, and the adjustment member engages the socket such that movement of the adjustment member adjusts the position of the socket relative to the first ball to thereby flex the catheter with the pull wires.

公开(公告)号：US20190209305A1

公开(公告)日：2019-07-11

申请号：US16141270

申请日：2018-09-25

Applicant: Edwards Lifesciences Corporation

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Alexander J. Siegel

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61B17/0643 ,  A61B17/122 ,  A61B17/1285 ,  A61B2017/00243 ,  A61B2017/00367 ,  A61F2/246 ,  A61F2/2466 ,  A61F2220/0016 ,  A61F2220/0075

Abstract: A system for implanting a repair device onto a native valve of a natural heart to repairing the native valve of a patient during a non-open-heart procedure. The system includes a paddle and a gripping member. The paddle is movable between an open position and a closed position. The gripping member has a weakened portion and a barbed portion. The barbed portion is configured to secure the gripping member to valve tissue of the native valve of the patient. A gripper control mechanism is configured to move the gripping member between an open position and a closed position. The gripper control mechanism comprises a suture removably attached to the gripping member at a first connection point and a pushing member configured to engage the gripping member at a second connection point. The weakened portion is between the first and second connection points. The pushing member is configured to push on the gripping member and the suture is configured to pull on the gripping member to flex the weakened portion and pivot the barbed portion.

公开(公告)号：US20190209297A1

公开(公告)日：2019-07-11

申请号：US16195598

申请日：2018-11-19

Applicant: Edwards Lifesciences Corporation

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Alexander J. Siegel

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0013

Abstract: A system for implanting a repair device onto a native valve of a natural heart to repairing the native valve of a patient during a non-open-heart procedure. The system includes a surgical delivery instrument, a valve repair device, and a gripper control mechanism. The surgical delivery instrument has at least one lumen. The valve repair device is configured to be delivered through the lumen of the surgical delivery instrument and to be attached to a native valve of a patient. The valve repair device has a pair of paddles, and first and second gripping members. The paddles are movable between an open position and a closed position. The paddles and the first and second gripping members are configured to attach to the native valve of the patient. The gripper control mechanisms each include a suture and a wire having a loop at a distal end. The suture extends from the surgical delivery instrument and through the loop of the wire. The suture is removably attached to the gripping member. The loop of the wire is configured to engage the gripping member to move the gripping member between one or more positions.

公开(公告)号：US10238493B1

公开(公告)日：2019-03-26

申请号：US15865934

申请日：2018-01-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric R. Dixon ,  Alexander J. Siegel

IPC: A61F2/24 ,  A61B17/29

Abstract: A system for implanting a repair device onto a native valve of a natural heart to repairing the native valve of a patient during a non-open-heart procedure. The system includes a surgical delivery instrument, a valve repair device, and a gripper control mechanism. The surgical delivery instrument has at least one lumen. The valve repair device is configured to be delivered through the lumen of the surgical delivery instrument and to be attached to a native valve of a patient. The valve repair device includes a pair of paddles, and at least four gripping members. The paddles are movable between an open position and a closed position, and the paddles and the at least four gripping members are configured to attach to the native valve of a patient. The gripper control mechanism is configured to independently move each of the at least four gripping members.

公开(公告)号：US20190069993A1

公开(公告)日：2019-03-07

申请号：US16179591

申请日：2018-11-02

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Grant Matthew Stearns ,  Sam Sok ,  Devin H. Marr ,  Tam Van Nguyen ,  Sirous Darabian ,  Gregory Scott Tyler, II ,  Lauren R. Freschauf ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: An exemplary valve repair system for repairing a native valve of a patient during a non-open-heart procedure has a delivery device and a valve repair device. The valve repair device is configured to be delivered through a lumen of the delivery device and to attach to a native valve of a patient. The valve repair device has first and second paddles and first and second gripping members. The first and second paddles are movable between an open position and a closed position. The first gripping member is attached to the first paddle and the second gripping member is attached to the second paddle. The gripping members are configured to attach to the native valve of the patient. A gripper control mechanism is configured to separately move the first and second gripping members.

公开(公告)号：US20190021851A1

公开(公告)日：2019-01-24

申请号：US16138728

申请日：2018-09-21

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Grant Matthew Stearns ,  Sam Sok ,  Devin H. Marr ,  Tam Van Nguyen ,  Sirous Darabian ,  Gregory Scott Tyler, II ,  Lauren R. Freschauf ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: An exemplary valve repair device for repairing a native valve of a patient has a paddle frame, and inner and outer paddle portions formed from a strip of metal fabric. The paddle frame has a round three-dimensional shape. The strip of metal fabric is attached to a closed attachment portion of the paddle frame.