公开(公告)号：US20210298898A1

公开(公告)日：2021-09-30

申请号：US17347458

申请日：2021-06-14

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar

IPC: A61F2/24

Abstract: A method of replacing a native heart valve utilizing a support structure comprising a first fastener, a second faster, a first leaflet brace, and a second leaflet brace. The first leaflet brace is configured to be advanced over a first guide wire to be adjacent to a portion of a first native leaflet. The second leaflet brace is configured to be advanced over a second guide wire to be adjacent to a portion of a second native leaflet. The first fastener and the second fastener are configured to be advanced over the first and second guide wires to respectively engage with first and second ends of the first leaflet brace and the second leaflet brace. A replacement heart valve is deployed within the native heart valve, thereby capturing the first and second leaflets between the support structure and the replacement heart valve.

公开(公告)号：US20200289257A1

公开(公告)日：2020-09-17

申请号：US16888649

申请日：2020-05-29

Applicant: Edwards Lifesciences Corporation

Inventor： Salvador Marquez ,  Da-Yu Chang ,  Cindy Woo ,  Hao-Chung Yang ,  Lynn T. Dang ,  Javier A. Sanguinetti ,  Alexander H. Siemons ,  Yaron Keidar ,  Virginia Qi Lin ,  Brian S. Conklin ,  Donald E. Bobo, JR.

IPC: A61F2/24 ,  A61B5/026 ,  A61B5/00

Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.

公开(公告)号：US20200038185A1

公开(公告)日：2020-02-06

申请号：US16600362

申请日：2019-10-11

Applicant: Edwards Lifesciences Corporation

Inventor： Mark A. Konno ,  Yaron Keidar

IPC: A61F2/24

Abstract: The invention is a cardiac implant, and associated methods therefore, configured to repair and/or replace a native heart valve, and having a support frame configured to be reshaped into an expanded/changed form in order to receive and/or support an expandable prosthetic heart valve therein. The implant may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace/repair a native valve (or other prosthetic heart valve), but to assume a generally non-rigid and/or expanded/expandable form when subjected to an outward force such as that provided by a dilation balloon. The implant may be configured to have a generally D-shaped configuration when initially implanted, but to assume a generally circular form when subjected to an outward force such as that provided by a dilation balloon.

公开(公告)号：US20190209309A1

公开(公告)日：2019-07-11

申请号：US16351402

申请日：2019-03-12

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61B17/064 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2463

Abstract: A system for repairing a native heart valve can comprise a first fastener, a second faster, a first leaflet brace, and a second leaflet brace. The first leaflet brace can be configured to extend partially around a first native leaflet. The second leaflet brace can be configured to extend partially around a second native leaflet. The first fastener can be configured to be deployed on respective first end portions of the first and second braces so as to connect the first end portions to each other. The second fastener can be configured to be deployed on respective second end portions of the first and second braces so as to connect the second end portions to each other. When the first end portions are connected to each other and the second end portions are connected to each other, the first and second leaflet braces encircle the first and second native leaflets.

公开(公告)号：US20190029829A1

公开(公告)日：2019-01-31

申请号：US16148864

申请日：2018-10-01

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar ,  Wesley V. Adzich ,  Dan Rottenberg ,  Boaz Manash ,  Alon Nahshon

IPC: A61F2/24

Abstract: An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle.

公开(公告)号：US20180353292A1

公开(公告)日：2018-12-13

申请号：US16104025

申请日：2018-08-16

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0016

Abstract: A prosthetic mitral valve assembly includes a valve component formed with a radially expandable frame and a valve structure supported inside of the frame. In one embodiment, the prosthetic mitral valve assembly further includes an expandable anchor having an annular base. A plurality of cantilevered fixation members extend from the base of the expandable anchor. The fixation members of the expandable anchor are adapted to rotate relative to a longitudinal axis as the valve component is radially expanded within the base of the expandable anchor. As the fixation members rotate, native mitral valve leaflets are securely captured between the fixation members of the anchor and the valve component.

公开(公告)号：US10130468B2

公开(公告)日：2018-11-20

申请号：US15403458

申请日：2017-01-11

Applicant: Edwards Lifesciences Corporation

Inventor： Stanton J. Rowe ,  Larry L. Wood ,  Henry Bourang ,  George Bakis ,  Benjamin Spenser ,  Netanel Benichou ,  Assaf Bash ,  Yaron Keidar

IPC: A61F2/24 ,  A61L27/36

Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.

公开(公告)号：US10064718B2

公开(公告)日：2018-09-04

申请号：US15092437

申请日：2016-04-06

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar

IPC: A61F2/24

Abstract: In one representative embodiment, a prosthetic valve assembly comprises a valve component comprising a radially compressible and expandable frame and a valve structure supported inside of the frame. The valve structure is configured to allow blood to flow through the valve component in one direction and block the flow of blood in the opposite direction. The assembly further comprises a radially compressible and expandable anchor comprising an annular base and a plurality of cantilevered fixation members extending from the base. The fixation members are configured to pivot inwardly toward the valve component when the valve component is radially expanded within the anchor.

公开(公告)号：US10010417B2

公开(公告)日：2018-07-03

申请号：US15130521

申请日：2016-04-15

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar

IPC: A61F2/24

CPC classification number: A61F2/2433 ,  A61F2/2418 ,  A61F2220/0008 ,  A61F2250/0063

Abstract: In one representative embodiment, a prosthetic valve assembly comprises a valve component comprising a radially compressible and expandable frame and a valve structure supported inside of the frame. The valve structure is configured to allow blood to flow through the valve component in one direction and block the flow of blood in the opposite direction. The assembly further comprises a radially compressible and expandable anchor comprising an annular base and a plurality of cantilevered fixation members extending from the base. The fixation members are configured to pivot inwardly toward the valve component when the valve component is radially expanded within the anchor.

公开(公告)号：US20180021129A1

公开(公告)日：2018-01-25

申请号：US15653390

申请日：2017-07-18

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2220/0008 ,  A61F2230/0013 ,  A61F2230/0054 ,  A61F2250/0003 ,  A61F2250/0014 ,  A61F2250/0018 ,  A61F2250/0036 ,  A61F2250/0039 ,  A61F2250/0063 ,  A61F2250/0069

Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.