摘要:
Apparatus is provided comprising a coiled sheet having a plurality of flaps mounted on its interior surface that project radially inward into a lumen formed by the interior surface of the apparatus when it is deployed. The flaps lie parallel to the interior surface of the sheet during transluminal delivery, but project radially inward once the apparatus is deployed. The flaps may comprise a fine mesh for use as a filter, or alternatively may be covered with a biocompatible material that is substantially impermeable, so as to partially or completely occlude the lumen. In a further alternative embodiment, the flaps may comprise a resilient biocompatible plastic or polymer, so that the flaps move in response to the flow and function as a pressure-based or directional valve.
摘要:
A prosthesis is provided for treatment of aneurysms, occlusive disease of vessels and body organs, and arterio-venous fistulas, comprising an expandable coiled sheet portion having a biocompatible graft affixed thereto. The graft material, preferably a polytetrafluoroethylene ("PTFE") or polyesther material, is affixed to the coiled sheet portion by sintering, suturing, or bonding using a biocompatible adhesive. The coiled sheet portion comprises a lattice formed from a biocompatible material, and may include one or more rows of locking teeth adjacent one edge of the coiled sheet that interengage openings in an opposing edge of the coiled sheet portion to retain the prosthesis at a desired expanded diameter. The prosthesis has a small delivery profile, making it suitable for use in a variety of body vessels. Methods of making and deploying the prosthesis are also provided.
摘要:
Devices for providing polymeric layers on the interior surface of body lumens and spaces are disclosed. The devices can include proximal and distal occlusion elements to define the treatment space and an optical emitter to provide light for a photopolymerization procedure. The devices may include a molding member for providing a thick polymeric gel. Alternatively, devices without a molding member may be used to carry out an interfacial polymerization procedure.
摘要:
A stent loading mechanism for automatically loading a stent onto a balloon delivery catheter of the kind used in typical percutaneous transluminal coronary angioplasty (PTCA) procedures. The device comprises a tubular member housing an elongated elastic bladder that surrounds the stent to be loaded. The distal end of the balloon catheter assembly and the stent are placed inside the tubular member and the bladder is inflated to compress and affix the stent onto the outside of the catheter assembly.
摘要:
Apparatus and methods are provided for use in filtering emboli from a vessel and/or performing thrombectomy and embolectomy, wherein a vascular device comprises one or more support hoops connected near a distal end of a guide wire, each support hoop having an articulation region, and a blood permeable sac affixed to the support hoop or hoops to form a mouth of the blood permeable sac. The mouth of the sac closes when the apparatus is collapsed for removal to prevent material from escaping from the sac.
摘要:
Apparatus and methods are provided for sealing a puncture through the wall of a patient's heart into a heart chamber, e.g., at the apex of the heart into the left ventricle. A positioning member is advanced into the puncture until a positioning element thereon is disposed within the chamber, the positioning element is expanded within the chamber, and the positioning member is withdrawn until the expanded positioning element contacts the endocardial wall of the chamber. A cartridge carrying a solid sealant is advanced over the positioning member, and the sealant is deployed within the puncture, e.g., offset proximally from the endocardial wall, the sealant expanding upon exposure to fluid within the puncture to seal the puncture.
摘要:
Apparatus and methods are provided for use in filtering emboli from a vessel and/or performing thrombectomy and embolectomy, wherein a vascular device comprises one or more support hoops connected near a distal end of a guide wire, each support hoop having an articulation region, and a blood permeable sac affixed to the support hoop or hoops to form a mouth of the blood permeable sac. The mouth of the sac closes when the apparatus is collapsed for removal to prevent material from escaping from the sac.
摘要:
Apparatus and methods are provided for use in filtering emboli from a vessel such as the ascending aorta, wherein a vascular device comprises a support hoop having an articulation region connected near a distal end of an elongated member, a blood permeable sac affixed to the support hoop so that the support hoop forms a mouth of the blood permeable sac, a guide wire, and a delivery sheath. The articulation region comprises a reduced thickness region of the support hoop that prevents kinks from forming in the support hoop when the apparatus is contracted to its delivery state, and curved regions that close the mouth of the sac to prevent material escaping from the sac when the apparatus is collapsed for removal.
摘要:
Apparatus and methods for retrieving a vascular filter from a vessel are provided wherein a retrieval adapter is delivered to a treatment site concurrently along with an interventional device to reduce the number of steps required to remove the vascular filter. The retrieval adapter also reduces the possibility of entangling the vascular filter with a stent disposed within the vessel during removal of the vascular filter. A separate retrieval catheter is also described for use in conjunction with the retrieval adapter.
摘要:
Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.