公开(公告)号：US20050260280A1

公开(公告)日：2005-11-24

申请号：US11193540

申请日：2005-07-28

Applicant: James Cook ,  Stanley Huth

Inventor： James Cook ,  Stanley Huth

IPC: A61K9/00 ,  A61K31/728 ,  A61K33/00 ,  A61K45/06 ,  A61P27/00 ,  A61P27/02 ,  A61K33/14

CPC classification number: A61K9/0048 ,  A61K31/728 ,  A61K33/00 ,  A61K45/06 ,  A61K2300/00

Abstract: Stable ophthalmic formulations comprising hyaluronic acid (sodium hyaluronate) as the primary active demulcent ingredient, stabilized oxy-chloro complex (available commercially as OcuPure(tm) from Advanced Medical Optics, Purite® from Allergan, and Purogene from Biocide) for preservative efficacy, balanced salts mimicking the tear film, and sodium borate as a buffer are disclosed. In one embodiment, preferred stable formulations may be used in the human eye with or without contact lenses. In another embodiment preferred formulations may also be used as a storage and conditioning solution for contact lenses following disinfection.

Abstract translation: 包含透明质酸（透明质酸钠）作为主要的活性缓和成分的稳定的眼用制剂，稳定的氧 - 氯络合物（可从Advanced Medical Optics，Allergan的Purite和来自杀生物剂的Purogene以商品名OcuPure（tm获得）），用于防腐​​功效 公开了模仿泪膜的平衡盐和作为缓冲剂的硼酸钠。 在一个实施方案中，优选的稳定制剂可以在具有或不具有隐形眼镜的人眼中使用。 在另一个实施方案中，优选的制剂也可以用作消毒后的隐形眼镜的储存和调理溶液。

公开(公告)号：US20050145851A1

公开(公告)日：2005-07-07

申请号：US10879695

申请日：2004-06-28

Applicant: Jerry Johnson ,  Ricardo Borges ,  Jeffrey Brown ,  James Cook ,  Allen Hanson ,  Edwin Piner ,  Pradeep Rajagopal ,  John Roberts ,  Sameer Singhal ,  Robert Therrien ,  Andrei Vescan

Inventor： Jerry Johnson ,  Ricardo Borges ,  Jeffrey Brown ,  James Cook ,  Allen Hanson ,  Edwin Piner ,  Pradeep Rajagopal ,  John Roberts ,  Sameer Singhal ,  Robert Therrien ,  Andrei Vescan

IPC: H01L21/285 ,  H01L21/329 ,  H01L21/335 ,  H01L29/20 ,  H01L29/872 ,  H01L29/15

CPC classification number: H01L29/7787 ,  H01L21/28587 ,  H01L21/7605 ,  H01L29/2003 ,  H01L29/66212 ,  H01L29/66462 ,  H01L29/872

Abstract: Gallium nitride material structures, including devices, and methods associated with the same are provided. In some embodiments, the structures include one or more isolation regions which electrically isolate adjacent devices. One aspect of the invention is the discovery that the isolation regions also can significantly reduce the leakage current of devices (e.g., transistors) made from the structures, particularly devices that also include a passivating layer formed on a surface of the gallium nitride material. Lower leakage currents can result in increased power densities and operating voltages, amongst other advantages.

Abstract translation: 提供了氮化镓材料结构，包括器件和与其相关的方法。 在一些实施例中，结构包括一个或多个隔离相邻器件的隔离区域。 本发明的一个方面是发现隔离区域还可以显着地减少由结构制成的器件（例如，晶体管）的泄漏电流，特别是还包括形成在氮化镓材料表面上的钝化层的器件。 较低的漏电流可以导致增加的功率密度和工作电压以及其它优点。

公开(公告)号：US20100317619A1

公开(公告)日：2010-12-16

申请号：US12779449

申请日：2010-05-13

Applicant: James Cook ,  Shengming Huang ,  Rahul Edwankar ,  Ojas A. Namjoshi ,  Zhi-Jian Wang

Inventor： James Cook ,  Shengming Huang ,  Rahul Edwankar ,  Ojas A. Namjoshi ,  Zhi-Jian Wang

IPC: A61K31/695 ,  A61K31/5517 ,  A61K31/551 ,  A61K31/5513 ,  A61P25/04 ,  A61P25/06

CPC classification number: C07D243/12 ,  C07D243/20 ,  C07D243/24 ,  C07D471/04 ,  C07D487/04 ,  C07D487/06 ,  C07D495/04 ,  C07D498/04 ,  C07D519/00

Abstract: In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of the often chronic, severe and debilitating pain that can accompany inflammatory diseases and neuropathic insults, pain that is often unresponsive to conventional analgesic treatment. The preferred embodiments of the present invention further relate to methods of treatment and pharmaceutical compositions using benzodiazepine derivatives that provide suppression, alleviation and prevention of neuropathic pain, migraine-related pain and inflammatory pain with reduced sedative and ataxic side effects.

Abstract translation: 在优选的实施方案中，本发明提供治疗方法和用于抑制，缓解和预防常伴有炎性疾病和神经性损伤的常规慢性，严重和衰弱性疼痛的药物组合物，其通常对常规镇痛治疗无反应。 本发明的优选实施方案还涉及使用苯并二氮杂衍生物的治疗方法和药物组合物，其提供抑制，缓解和预防神经性疼痛，偏头痛相关疼痛和炎症性疼痛，同时具有降低的镇静和共济失调副作用。

公开(公告)号：US20100053330A1

公开(公告)日：2010-03-04

申请号：US12198678

申请日：2008-08-26

Applicant: Dean R. Hellickson ,  Kurt Holmquist ,  James Cook ,  Robert Burns ,  Andrew W. Guyette

Inventor： Dean R. Hellickson ,  Kurt Holmquist ,  James Cook ,  Robert Burns ,  Andrew W. Guyette

IPC: H04N7/18 ,  G06K9/00

CPC classification number: G01S17/023 ,  G01S7/4802 ,  G01S17/42 ,  G01S17/89 ,  G01S19/13 ,  G08B13/181 ,  G08B13/19645

Abstract: A security sensor system comprises one or more laser detection and ranging (LADAR) sensors configured for accumulation of three-dimensional image data. In one embodiment, the one or more LADAR sensors each comprise a LADAR device, such as a MEMS device, configured to transmit a plurality of laser pulses, and a microprocessor operatively coupled to the LADAR device. One or more data storage devices is operatively coupled to the microprocessor and configured to store the three-dimensional image data, as well as predetermined protected area boundary and fixed object definitions. A GPS receiver can be operatively coupled to the microprocessor and a GPS antenna. The microprocessor is configured to perform a LADAR image analysis that compares the three-dimensional image data with the protected area boundary and fixed object definitions to identify one or more potential intruders.

Abstract translation: 安全传感器系统包括被配置用于累积三维图像数据的一个或多个激光检测和测距（LADAR）传感器。 在一个实施例中，一个或多个LADAR传感器各自包括被配置为传输多个激光脉冲的LADAR装置，诸如MEMS装置，以及可操作地耦合到LADAR装置的微处理器。 一个或多个数据存储设备可操作地耦合到微处理器并被配置为存储三维图像数据以及预定的保护区域边界和固定对象定义。 GPS接收机可以可操作地耦合到微处理器和GPS天线。 微处理器被配置为执行将三维图像数据与保护区边界和固定对象定义进行比较的LADAR图像分析，以识别一个或多个潜在入侵者。

公开(公告)号：US20090072076A1

公开(公告)日：2009-03-19

申请号：US11470900

申请日：2006-09-07

Applicant: ROBERT BRINKERHOFF ,  Michael Mahnken ,  Richard Loehr ,  James Cook

Inventor： ROBERT BRINKERHOFF ,  Michael Mahnken ,  Richard Loehr ,  James Cook

IPC: F42B15/01

CPC classification number: F42B10/661 ,  G05D1/0883

Abstract: A reliable and inexpensive attitude control system uses a plurality of pitch-over thrusters to perform rapid and precise attitude maneuvers for a flight vehicle. The pitch-over thrusters create rotational moments that directly pitch and yaw the flight vehicle. The use of very simple thrusters and control techniques provides for a reliable and cost effective solution. The ability to perform overlapping pitch and yaw maneuvers with single-shot fixed-impulse thrusters provides for high-speed maneuverability.

Abstract translation: 可靠和廉价的姿态控制系统使用多个俯仰推进器来为飞行器执行快速和精确的姿态操纵。 俯仰推进器产生直接俯仰和偏航飞行器的旋转力矩。 使用非常简单的推进器和控制技术提供了可靠且具有成本效益的解决方案。 使用单次固定脉冲推进器执行重叠俯仰和偏航操作的能力提供高速机动性。

公开(公告)号：US20080108605A1

公开(公告)日：2008-05-08

申请号：US11929860

申请日：2007-10-30

Applicant: James Cook ,  Qi Huang ,  Xiaohui He ,  Xiaoyan Li ,  Jianming Yu ,  Dongmei Han

Inventor： James Cook ,  Qi Huang ,  Xiaohui He ,  Xiaoyan Li ,  Jianming Yu ,  Dongmei Han

IPC: A61K31/5517 ,  A61P25/22 ,  C07D243/14 ,  A61K31/5513 ,  C07D487/12

CPC classification number: C07D471/04 ,  C07D243/12 ,  C07D243/20 ,  C07D243/24 ,  C07D487/04 ,  C07D487/06 ,  C07D495/04 ,  C07D495/14 ,  C07D498/04 ,  C07D519/00

Abstract: Orally active benzodiazepine derivatives and their salts are disclosed. These compounds and their salts have anxiolytic and anticonvulsant activity with reduced sedative/hypnotic/muscle relaxant/ataxic effects.

Abstract translation: 公开了口服活性苯二氮卓衍生物及其盐。 这些化合物及其盐具有抗焦虑和抗惊厥活性，降低镇静/催眠/肌肉松弛/共济失调作用。

公开(公告)号：US20070180476A1

公开(公告)日：2007-08-02

申请号：US11710461

申请日：2007-02-22

Applicant: David Muoio ,  James Cook ,  Richard Hasha

Inventor： David Muoio ,  James Cook ,  Richard Hasha

IPC: G06F3/00 ,  H04N7/18 ,  G09G5/00 ,  G06F3/048

CPC classification number: H04L67/02 ,  G06F8/38 ,  G06F9/449 ,  G06F9/465 ,  G06Q90/00 ,  G06T1/00 ,  H04L12/2803 ,  H04L12/2834 ,  H04L2012/2849 ,  H04N21/26258 ,  H04N21/43615 ,  H05B37/02 ,  H05B37/0254 ,  H05B37/029

Abstract: An art distribution system for distributing art to multiple display devices within an environment. The art distribution system provides a technique for specifying images to be displayed in an environment. The art distribution system provides a hierarchical representation of spaces within the environment. Each space may be further subdivided into subspaces. The art distribution system allows a user to select a space within the hierarchy and then to select an image that is to be displayed at the display devices within the selected space. The art distribution system then displays the selected image within the space including within all subspaces of the selected space. The art distribution system may allow a subsequent assignment of the image to a subspace to override within that subspace the previous selection of an image for the space.

公开(公告)号：US07249344B1

公开(公告)日：2007-07-24

申请号：US09323210

申请日：1999-06-01

Applicant: James Zeanah ,  Charles Abbott ,  Nik Boyd ,  Albert Cohen ,  James Cook ,  Michael Grandcolas ,  Sikhun Lan ,  Bonnie Lindsley ,  Grigor Markarian ,  Leslie Moss

Inventor： James Zeanah ,  Charles Abbott ,  Nik Boyd ,  Albert Cohen ,  James Cook ,  Michael Grandcolas ,  Sikhun Lan ,  Bonnie Lindsley ,  Grigor Markarian ,  Leslie Moss

IPC: G06F9/44

CPC classification number: G06Q20/30 ,  G06Q20/32 ,  G06Q20/322 ,  G06Q20/3227 ,  G06Q20/3552 ,  G06Q40/00 ,  G07F19/206

Abstract: A financial institution can provide financial services to a plurality of remote devices, such as personal computers, personal data assistants, screen phones, automatic teller machines, external service providers, and internally to staff terminals and individual branches. By separating the components of the system into independent components, the system and method can be developed and tested on a component level rather than the entire system level, thereby reducing the development and maintenance cycle time. The system and method operate in sessions and can employ a dialog component for gathering information from a customer, a rule broker component for providing answers to the various legal and regulatory rules in a particular country, a language man component for selecting appropriate language, a transaction executor component for performing transactions, and a presentation manager component for formatting outputs to the customer.

Abstract translation: 金融机构可以向个人计算机，个人数据助理，屏幕电话，自动取款机，外部服务提供商等多个远程设备提供金融服务，并且向内部向员工终端和各个分支机构提供金融服务。 通过将系统的组件分离成独立的组件，可以在组件级别而不是整个系统级别上开发和测试系统和方法，从而减少开发和维护周期时间。 该系统和方法在会话中进行操作，并且可以使用用于从客户收集信息的对话组件，用于提供特定国家的各种法律和规则规则的答案的规则代理组件，用于选择适当语言的语言人组件，交易 执行交易的执行者组件，以及用于将输出格式化给客户的演示管理器组件。

公开(公告)号：US20070105851A1

公开(公告)日：2007-05-10

申请号：US10579938

申请日：2004-11-04

Applicant: James Cook ,  Cheng Bi ,  Gaetan Ladouceur

Inventor： James Cook ,  Cheng Bi ,  Gaetan Ladouceur

IPC: A61K31/541 ,  A61K31/5377 ,  C07D498/02 ,  A61K31/498

CPC classification number: C07D495/04

Abstract: This invention relates to a compound of Formula (I): (I) and its use in treating hyper-proliferative disorders and diseases associated with angiogenesis.

Abstract translation: 本发明涉及式（I）的化合物：（I）及其用于治疗与血管生成相关的高增殖性疾病和疾病。

公开(公告)号：US20070068235A1

公开(公告)日：2007-03-29

申请号：US11237360

申请日：2005-09-27

Applicant: Scott Bunyer ,  Steven Magee ,  Fred Hintz ,  Richard Andrews ,  Gary O' Brien ,  James Liu ,  James Cook ,  Stephen Shiffer

Inventor： Scott Bunyer ,  Steven Magee ,  Fred Hintz ,  Richard Andrews ,  Gary O' Brien ,  James Liu ,  James Cook ,  Stephen Shiffer

IPC: G01M15/00

CPC classification number: G01L3/1428

Abstract: A torque sensor system and method. An automotive engine is located opposite a torque converter, such that a shaft extends from the engine and interacts with the torque converter. A target is located between the engine and torque converter. One or more torque sensors can be integrated with one or more position sensors for detecting a position associated with the shaft, wherein the torque sensor(s) and the position sensor(s) are integrated into a single torque sensor package to thereby provide enhanced sensing of the target in association with a rotation of shaft during an actuation of the engine.