公开(公告)号：US11852624B1

公开(公告)日：2023-12-26

申请号：US18103746

申请日：2023-01-31

Applicant: Jin He ,  Santosh Khatri ,  Popular Pandey

Inventor： Jin He ,  Santosh Khatri ,  Popular Pandey

IPC: G01N27/327 ,  G01N33/487 ,  G01N27/447 ,  G01Q60/44

CPC classification number: G01N33/48721 ,  G01N27/44791 ,  G01Q60/44

Abstract: A system, apparatus, device and/or method for electrical label-free detection of single molecule via a glass or quartz nanopipette biosensor, one type of solid state nanopore biosensor based on resistive pulse measurements, are provided. The method of the subject invention effectively slows down the motion of biomolecules and concentrates them at the nanopipette tip. By driving biomolecules to come out of the nanopipette barrel and move in the fibrin hydrogel, unprecedented sensitivity using the typical size nanopipettes can be achieved. Small molecules such as doxorubicin, ATP, GTP, and short peptides can be easily detected with very high event rate, which greatly reduces the fabrication and measurement difficulties and open opportunities for various new applications for nanopipette biosensors.

公开(公告)号：US09140682B2

公开(公告)日：2015-09-22

申请号：US13395956

申请日：2011-01-31

Applicant: Stuart Lindsay ,  Shuai Chang ,  Jin He ,  Peiming Zhang ,  Shuo Huang

Inventor： Stuart Lindsay ,  Shuai Chang ,  Jin He ,  Peiming Zhang ,  Shuo Huang

IPC: G01N27/00 ,  G01N33/487

CPC classification number: G01N33/48721 ,  C12Q1/6869 ,  G01N27/3275 ,  Y10T436/143333

Abstract: The invention includes compositions, devices, and methods for analyzing a polymer and/or polymer unit. The polymer may be a homo or hetero-polymer such as DNA, RNA, a polysaccharide, or a peptide. The device includes electrodes that form a tunnel gap through which the polymer can pass. The electrodes are functionalized with a reagent attached thereto, and the reagent is capable of forming a transient bond to a polymer unit. When the transient bond forms between the reagent and the unit, a detectable signal is generated and used to analyze the polymer.

Abstract translation: 本发明包括用于分析聚合物和/或聚合物单元的组合物，装置和方法。 聚合物可以是同质或异聚合物，例如DNA，RNA，多糖或肽。 该装置包括形成隧道间隙的电极，聚合物可通过该间隙通过。 电极用附着于其上的试剂进行功能化，并且试剂能够形成与聚合物单元的暂时结合。 当试剂和单元之间形成瞬态键时，产生可检测的信号并用于分析聚合物。

公开(公告)号：US20130336128A1

公开(公告)日：2013-12-19

申请号：US13517838

申请日：2012-06-14

Applicant: Venson M. Shaw ,  Jin He

Inventor： Venson M. Shaw ,  Jin He

IPC: H04L12/26

CPC classification number: H04L41/5038 ,  H04L43/103 ,  H04L43/12 ,  H04L47/12 ,  H04L47/323 ,  H04W24/00 ,  H04W24/02

Abstract: An operation, administration, and maintenance data sink may receive an event data packet. The event data packet may be processed and transmitted based on instructions from a controller, wherein the controller may regulate the transmission of the processed event data packet based on network conditions.

Abstract translation: 操作，管理和维护数据宿可以接收事件数据分组。 可以基于来自控制器的指令来处理和发送事件数据分组，其中控制器可以基于网络条件来调节处理的事件数据分组的传输。

公开(公告)号：US20080034012A1

公开(公告)日：2008-02-07

申请号：US11498594

申请日：2006-08-02

Applicant: Lev Novik ,  Douglas B. Terry ,  Irena Hudis ,  Jeremie E. Sartor ,  Shaoyu Zhou ,  Tomas Talius ,  Yunxin Wu ,  Jin He ,  Mark Scurrell

Inventor： Lev Novik ,  Douglas B. Terry ,  Irena Hudis ,  Jeremie E. Sartor ,  Shaoyu Zhou ,  Tomas Talius ,  Yunxin Wu ,  Jin He ,  Mark Scurrell

IPC: G06F17/30

CPC classification number: G06F17/30176 ,  Y10S707/99934 ,  Y10S707/99938 ,  Y10S707/99952 ,  Y10S707/99953 ,  Y10S707/99955

Abstract: Extending hierarchical synchronization (sync) scopes to non-hierarchical scenarios may involve a method for synchronizing differently organized data stores comprising mapping different physical organizations to similar logical organizations and utilizing an organization-based synchronization algorithm to synchronize the differently organized stores. Also, the uniqueness constraints of the organizations may be preserved as well as the parent-child ordering constraints of the organizations.

Abstract translation: 将分级同步（同步）范围扩展到非分层场景可能涉及用于同步不同组织的数据存储的方法，包括将不同的物理组织映射到类似的逻辑组织，并利用基于组织的同步算法来同步不同组织的存储。 此外，组织的唯一性限制也可能受到组织的父母子女排序限制的限制。

公开(公告)号：US06927661B2

公开(公告)日：2005-08-09

申请号：US10428963

申请日：2003-05-02

Applicant: Jin He ,  Michael Duane Lawrence ,  Gordon K. Y. Lee ,  Victor Ke-Ji Lee ,  Donald Bruce Rose

Inventor： Jin He ,  Michael Duane Lawrence ,  Gordon K. Y. Lee ,  Victor Ke-Ji Lee ,  Donald Bruce Rose

IPC: H01F21/12 ,  H01F27/28 ,  H01F27/38 ,  H01F5/00

CPC classification number: H01F27/2804 ,  H01F21/12 ,  H01F27/38 ,  H02M2001/0064 ,  Y10T29/4902

Abstract: The magnetic device consists of a planar winding board, which contains the windings for both the inductor and the transformer. Thus, this invention centers on integrating the windings of multiple magnetic devices, not integrating the cores. By connecting the transformer secondary winding directly to the output inductor winding without using any intermediate headers and/or termination pins or conductive copper traces, both electrical path and the termination resistance will be minimized. Furthermore, the number of headers or termination pins required will also be reduced, which helps to not only alleviate the issue associated with co-planarity of the termination pins, but also reduce the cost of the material and manufacturing.

Abstract translation: 磁性装置由平面绕组板组成，其中包含用于电感器和变压器的绕组。 因此，本发明的重点是集成多个磁性装置的绕组，而不是集成磁芯。 通过将变压器次级绕组直接连接到输出电感器绕组，而不使用任何中间接头和/或端接引脚或导电铜迹线，电气路径和终端电阻将最小化。 此外，所需的头部或终端销的数量也将减少，这有助于不仅减轻与终端销的共面性相关的问题，而且还降低了材料和制造的成本。

公开(公告)号：US20050025761A1

公开(公告)日：2005-02-03

申请号：US10642100

申请日：2003-08-15

Applicant: Philip Thorpe ,  M. Soares ,  Jin He

Inventor： Philip Thorpe ,  M. Soares ,  Jin He

IPC: A61K39/395 ,  C07K16/28 ,  C07K16/44 ,  A61K31/7072 ,  A61K31/7076 ,  A61K38/17

CPC classification number: A61K39/395 ,  A61K39/39558 ,  A61K47/62 ,  A61K47/6811 ,  A61K47/6835 ,  A61K47/6849 ,  A61K2039/505 ,  C07K16/18 ,  C07K16/2836 ,  C07K16/44 ,  C07K2317/24 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/77 ,  A61K2300/00

Abstract: Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.

Abstract translation: 公开了关于阴离子磷脂和氨基磷脂在肿瘤血管系统和病毒进入和扩散中的作用的惊人发现，以及利用这些发现在治疗癌症和病毒感染中的组合物和方法。还公开了有利的抗体，免疫缀合物和基于杜氏霉素的组合物 以及结合和抑制阴离子磷脂和氨基磷脂的组合，用于安全和有效治疗癌症，病毒感染和相关疾病。

公开(公告)号：US06169649A

公开(公告)日：2001-01-02

申请号：US09354980

申请日：1999-07-16

Applicant: Greg H. Fasullo ,  Jin He ,  John A. Herrmann ,  Greg P. Jorgenson

Inventor： Greg H. Fasullo ,  Jin He ,  John A. Herrmann ,  Greg P. Jorgenson

IPC: H02H100

CPC classification number: H02H3/046

Abstract: For use with a power supply having first and second circuit protection devices, a detection circuit, a method of monitoring the protection devices and a power supply employing the circuit or the method. In one embodiment, the detection circuit includes (1) a bridge circuit coupled to the first and second circuit protection devices, (2) a resistor parallel-coupled across one of the first and second circuit protection devices and (3) a sensing circuit, coupled to the bridge circuit and the resistor, that senses an imbalance in the bridge circuit and develops therefrom a failure signal when at least one of the first and second circuit protection devices becomes inoperable.

Abstract translation: 用于具有第一和第二电路保护装置的电源，检测电路，监控保护装置的方法和采用电路或方法的电源。 在一个实施例中，检测电路包括（1）耦合到第一和第二电路保护装置的桥式电路，（2）跨过第一和第二电路保护装置之一并联耦合的电阻器，以及（3）感测电路， 耦合到桥式电路和电阻器，其感测桥式电路中的不平衡，并且在第一和第二电路保护装置中的至少一个变得不可操作时从其产生故障信号。

公开(公告)号：US06163266A

公开(公告)日：2000-12-19

申请号：US207450

申请日：1998-12-08

Applicant: Greg H. Fasullo ,  Jin He ,  Greg P. Jorgenson ,  Victor K. Lee

Inventor： Greg H. Fasullo ,  Jin He ,  Greg P. Jorgenson ,  Victor K. Lee

IPC: F04D27/02 ,  H02H3/04 ,  H02H7/093 ,  G08B21/00

CPC classification number: H02H7/093 ,  F04D27/008 ,  H02H3/04

Abstract: For use with a DC fan, a detection circuit and a method of detecting an operational condition thereof. In one embodiment, the detection circuit includes: (1) a sensor, coupled to the DC fan, that senses a current through the sensorless DC fan and produces an intermediate signal based thereon and (2) an alarm circuit, coupled to the sensor, that compares the intermediate signal to a range defined by an upper limit signal and a lower limit signal and generates an alarm signal when the intermediate signal is outside of the range.

Abstract translation: 用于DC风扇，检测电路和检测其操作条件的方法。 在一个实施例中，检测电路包括：（1）耦合到DC风扇的传感器，其感测通过无传感器的DC风扇的电流并基于其产生中间信号;以及（2）耦合到传感器的报警电路， 其将中间信号与由上限信号和下限信号限定的范围进行比较，并且当中间信号在该范围之外时产生报警信号。

公开(公告)号：US6020735A

公开(公告)日：2000-02-01

申请号：US65957

申请日：1998-04-24

Applicant: Rick L. Barnett ,  Frank H. Chavez ,  Jin He ,  Anthony J. Scocca

Inventor： Rick L. Barnett ,  Frank H. Chavez ,  Jin He ,  Anthony J. Scocca

IPC: G01R1/20 ,  G01R19/15 ,  G01R31/327

CPC classification number: G01R1/206

Abstract: An internal diode detection circuit for a device under test (DUT), a method of operating and a test fixture employing the same. In one embodiment, the internal diode detection circuit includes a source of electrical power that applies a reverse bias voltage to the DUT. The internal diode detection circuit also includes a current indicator, series-coupled to the DUT, that generates a signal when a current flows through the DUT. The signal indicates a presence of an internal diode in the DUT.

Abstract translation: 一种用于待测器件（DUT）的内部二极管检测电路，一种操作方法和使用该二极管的测试夹具。 在一个实施例中，内部二极管检测电路包括向DUT施加反向偏置电压的电源。 内部二极管检测电路还包括串联耦合到DUT的电流指示器，当电流流过DUT时产生信号。 该信号表示DUT中存在内部二极管。

公开(公告)号：US5861734A

公开(公告)日：1999-01-19

申请号：US950335

申请日：1997-10-14

Applicant: Greg H. Fasullo ,  Jin He ,  Mark Elliott Jacobs ,  Yimin Jiang

Inventor： Greg H. Fasullo ,  Jin He ,  Mark Elliott Jacobs ,  Yimin Jiang

IPC: H02M3/158 ,  G05F1/10 ,  G05F1/56

CPC classification number: H02M1/4216 ,  H02M2003/1586 ,  Y02B70/126 ,  Y02P80/112

Abstract: A control system for an converter circuit using two interleaved boost circuits is described which uses a single PWM controller to control the switches in both of the interleaved boost circuits. A voltage feedback control circuit monitors the output voltage of the converter circuit and sends that information to the PWM controller. A current sensing circuit is provided that senses the current in each of the boost converters. The current sensed in the current sensing circuit is converted to a voltage and used in conjunction with the voltage information from voltage feedback control circuit by the single PWM controller to regulate both of the boost converter switches. By regulating the boost converter switches, the single PWM controller is able to ensure proper synchronization and current sharing while tightly regulating the output voltage and improving the input power factor of the converter circuit.

Abstract translation: 描述了使用两个交错升压电路的转换器电路的控制系统，其使用单个PWM控制器来控制两个交错升压电路中的开关。 电压反馈控制电路监视转换器电路的输出电压，并将该信息发送给PWM控制器。 提供了感测每个升压转换器中的电流的电流感测电路。 在电流感测电路中感测到的电流被转换成电压，并与来自电压反馈控制电路的电压信息结合使用，由单个PWM控制器调节两个升压转换器开关。 通过调节升压转换器开关，单个PWM控制器能够确保正确的同步和电流共享，同时严格调节输出电压并提高转换器电路的输入功率因数。