Use of FOXC2 in diagnosing, preventing and treating cancer metastasis
    41.
    发明授权
    Use of FOXC2 in diagnosing, preventing and treating cancer metastasis 有权
    使用FOXC2诊断,预防和治疗癌症转移

    公开(公告)号:US08088590B2

    公开(公告)日:2012-01-03

    申请号:US11646706

    申请日:2006-12-28

    IPC分类号: G01N33/574 C12Q1/68

    摘要: The invention relates to methods and compositions for inhibiting metastasis, such as by inhibiting FOXC2 expression or activity. The invention further relates to methods of prognosticating, diagnosing, and assisting in the diagnosis of metastasis in an individual, or of determining the metastatic potential of a tumor. The invention further relates to methods of identifying agents which inhibit metastasis.

    摘要翻译: 本发明涉及抑制转移的方法和组合物,例如通过抑制FOXC2表达或活性。 本发明还涉及预测,诊断和辅助个体中转移的诊断或确定肿瘤的转移潜力的方法。 本发明还涉及鉴定抑制转移的药物的方法。

    System and method for detecting an object in a high dimensional space
    42.
    发明授权
    System and method for detecting an object in a high dimensional space 有权
    用于检测高维空间中的对象的系统和方法

    公开(公告)号:US08009900B2

    公开(公告)日:2011-08-30

    申请号:US11856208

    申请日:2007-09-17

    IPC分类号: G06K9/00 G06K9/62

    CPC分类号: G06K9/6292

    摘要: A system and method for detecting an object in a high dimensional image space is disclosed. A three dimensional image of an object is received. A first classifier is trained in the marginal space of the object center location which generates a predetermined number of candidate object center locations. A second classifier is trained to identify potential object center locations and orientations from the predetermined number of candidate object center locations and maintaining a subset of the candidate object center locations. A third classifier is trained to identify potential locations, orientations and scale of the object center from the subset of the candidate object center locations. A single candidate object pose for the object is identified.

    摘要翻译: 公开了一种用于检测高维图像空间中的对象的系统和方法。 接收对象的三维图像。 在对象中心位置的边缘空间中训练第一分类器,其生成预定数量的候选对象中心位置。 训练第二分类器以从预定数量的候选对象中心位置识别潜在对象中心位置和方向,并维护候选对象中心位置的子集。 训练第三分类器以从候选对象中心位置的子集中识别对象中心的潜在位置,方向和尺度。 识别对象的单个候选对象姿势。

    METHOD AND APPARATUS FOR ELIMINATING FREQUENCY-DOMAIN INTERFERENCE SIGNALS
    44.
    发明申请
    METHOD AND APPARATUS FOR ELIMINATING FREQUENCY-DOMAIN INTERFERENCE SIGNALS 有权
    消除频域干扰信号的方法和装置

    公开(公告)号:US20100226464A1

    公开(公告)日:2010-09-09

    申请号:US12636333

    申请日:2009-12-11

    IPC分类号: H04B1/10

    CPC分类号: H04B1/7107 H04B1/7102

    摘要: The present invention discloses a method and an apparatus for eliminating frequency-domain interference signals, and relates to communication technologies. The method includes: multiplying a frequency-domain channel estimation value by a frequency-domain interference signal to obtain a frequency-domain received interference signal; and subtracting the frequency-domain received interference signal from the frequency-domain received signal to obtain the frequency-domain received signal free of interference. The apparatus includes a multiplying module and a subtracting module. A frequency-domain equalizer includes an interference signal obtaining module and an interference signal eliminating module. The technical solution provided herein eliminates interference signals in the frequency domain, and saves the calculation load in contrast with elimination of time-domain interference signals.

    摘要翻译: 本发明公开了一种消除频域干扰信号的方法和装置,涉及通信技术。 该方法包括:将频域信道估计值乘以频域干扰信号以获得频域接收干扰信号; 并从频域接收信号中减去频域接收干扰信号,得到无干扰的频域接收信号。 该装置包括乘法模块和减法模块。 频域均衡器包括干扰信号获取模块和干扰信号消除模块。 这里提供的技术方案消除了频域中的干扰信号,并且与消除时域干扰信号相反,节省了计算负荷。

    Cover assembly for access openings
    45.
    发明授权
    Cover assembly for access openings 失效
    用于进出口的盖组件

    公开(公告)号:US07712627B2

    公开(公告)日:2010-05-11

    申请号:US12168524

    申请日:2008-07-07

    IPC分类号: B65D43/16 E05D3/18

    摘要: An exemplary cover assembly includes a bezel, and a spring-loaded cover. The bezel includes an opening, a pair of slots, and a pair of pins. The opening is defined in the bezel for accessing a device installed thereto. The slots are defined adjacent opposite ends of the opening respectively. The pins are formed adjacent the slots respectively. The spring-loaded cover covers the opening of the bezel, includes a pair of fixing plates formed thereon slidably received in the slots of the bezel. Each of the fixing plates defines an arcuate groove that slidably receives the corresponding pin of the bezel, where the cover is capable of being pivoted open and shut.

    摘要翻译: 示例性的盖组件包括边框和弹簧加载的盖。 挡板包括一个开口,一对插槽和一对插针。 开口被限定在挡板中用于访问安装在其上的装置。 槽分别限定在开口的两端。 销分别形成在狭槽附近。 弹簧加载的盖覆盖边框的开口,包括一对形成在其上的固定板,其可滑动地容纳在边框的槽中。 每个固定板限定了一个弧形槽,其可滑动地容纳挡板的相应销,其中盖能够枢转打开和关闭。

    Growth arrest specific gene 6 peptides, antibodies, compositions, methods and uses
    48.
    发明授权
    Growth arrest specific gene 6 peptides, antibodies, compositions, methods and uses 有权
    生长停滞特异性基因6肽,抗体,组合物,方法和用途

    公开(公告)号:US07547767B2

    公开(公告)日:2009-06-16

    申请号:US11602865

    申请日:2006-11-21

    IPC分类号: C07K16/46

    摘要: The present invention provides novel proteins and peptides from the receptor binding region of human Growth Arrest Specific Gene 6 (Gas6) and antibodies, including specified portions or variants, specific for at least one such Gas6 peptide or fragment thereof. The aforesaid peptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-Gas6 antibodies. The invention also provides for the nucleic acids encoding such peptides and anti-Gas6 antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, including therapeutic formulations, administration and devices. Fifteen novel peptide sequences from the Gas6 G domain that are implicated in Gas6 interactions with its receptors are identified, isolated, and synthesized so as to allow generation of anti-Gas6 antibodies. The peptide sequences include three ESTs that encompass regions predicted to contribute to receptor binding or that can raise anti-Gas6 antibodies. This invention provides for such antibodies to be used in modulating or treating at least one Gas6-related disease in a cell, tissue, organ, animal, or patient. Such diseases may include, but are not limited to, thromboembolic disease, ischemic disease, venous thromboembolism, arterial or venous thrombosis, pulmonary embolism, restenosis, diabetic angiopathy and allograft atherosclerosis.

    摘要翻译: 本发明提供了来自人生长抑制特异性基因6(Gas6)的受体结合区的新型蛋白质和肽,以及对至少一种这样的Gas6肽或其片段特异的包括特定部分或变体的抗体。 上述肽可用于产生人,灵长类动物,啮齿动物,哺乳动物,嵌合,人源化和/或CDR移植的抗Gas6抗体。 本发明还提供了编码这些肽和抗Gas6抗体的核酸,互补核酸,载体,宿主细胞,以及制备和使用它们的方法,包括治疗制剂,给药和装置。 鉴定,分离和合成来自Gas6G结构域的15个新的肽序列,其与其受体相关的Gas6相互作用,以便产生抗Gas6抗体。 肽序列包括三个EST,其包含预期有助于受体结合的区域或可产生抗Gas6抗体。 本发明提供这样的抗体用于调节或治疗细胞,组织,器官,动物或患者中的至少一种Gas6相关疾病。 这些疾病可以包括但不限于血栓栓塞性疾病,缺血性疾病,静脉血栓栓塞,动脉或静脉血栓形成,肺栓塞,再狭窄,糖尿病性血管病和同种异体移植动脉粥样硬化。

    METHOD AND SYSTEM FOR REMOVING RADIO FREQUENCY DIRECT CURRENT OFFSET IN SIGNAL
    49.
    发明申请
    METHOD AND SYSTEM FOR REMOVING RADIO FREQUENCY DIRECT CURRENT OFFSET IN SIGNAL 有权
    用于消除无线电频率直接电流偏移信号的方法和系统

    公开(公告)号:US20080076376A1

    公开(公告)日:2008-03-27

    申请号:US11848001

    申请日:2007-08-30

    IPC分类号: H04B1/26

    CPC分类号: H04B1/30 H04L25/063

    摘要: Embodiments of the present invention provide a method and a system for removing a Radio Frequency (RF) Direct Current (DC) offset in a signal. The method includes: subtracting a canceling DC from a signal carrying an RF DC offset and generating an RF DC offset residual; outputting the signal when the RF DC offset residual in the signal is zero; adjusting the canceling DC according to the RF DC offset residual in the signal if the RF DC offset residual is not zero. The system includes a receiver, an RF DC offset canceling unit, a determining unit, a canceling DC adjusting unit, and an output unit. With embodiments of the present invention, the RF DC offset in the signal may be effectively removed.

    摘要翻译: 本发明的实施例提供一种用于去除信号中的射频(RF)直流(DC)偏移的方法和系统。 该方法包括:从承载RF DC偏移的信号中减去消除DC并产生RF DC偏移残差; 当信号中的RF DC偏移残差为零时,输出信号; 如果RF DC偏移残差不为零,则根据信号中的RF DC偏移残差调整抵消DC。 该系统包括接收器,RF DC偏移消除单元,确定单元,消除DC调整单元和输出单元。 利用本发明的实施例,可以有效地消除信号中的RF DC偏移。

    Data processing system for a multi-function device
    50.
    发明授权
    Data processing system for a multi-function device 有权
    用于多功能设备的数据处理系统

    公开(公告)号:US07336972B2

    公开(公告)日:2008-02-26

    申请号:US10809411

    申请日:2004-03-26

    IPC分类号: H04B1/38

    摘要: To enable a main terminal device to implement specific functions in cooperation with a sub terminal device, when a fax machine serving as the main terminal device stores conversion request data in a shared area of its RAM (S130), a personal computer serving as the sub terminal device generates converted image data based on the conversion request data stored on the fax machine end and stores the resulting data on the fax machine end. Subsequently, the fax machine reads the converted image data stored by the personal computer and transmits this image data. In this way, the fax machine can direct the personal computer to execute part of the process simply by storing request data in a shared area of the RAM, thereby transmitting converted image data in cooperation with the personal computer.

    摘要翻译: 为了使主终端装置与子终端装置协同实现特定的功能,当用作主终端装置的传真机将转换请求数据存储在其RAM的共享区域中时(S130),作为 子终端设备基于存储在传真机端的转换请求数据生成转换的图像数据,并将结果数据存储在传真机端。 随后,传真机读取由个人计算机存储的转换的图像数据并发送该图像数据。 以这种方式,传真机可以通过将请求数据存储在RAM的共享区域中来指导个人计算机执行部分处理,从而与个人计算机协作传送转换的图像数据。