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    Apo-2 ligand
    41.
    发明授权
    Apo-2 ligand 失效
    Apo-2配体抗体

    公开(公告)号：US6046048A

    公开(公告)日：2000-04-04

    申请号：US780496

    申请日：1997-01-08

    申请人： Avi J. Ashkenazi ,  Anan Chuntharapai ,  Kyung Jin Kim

    发明人： Avi J. Ashkenazi ,  Anan Chuntharapai ,  Kyung Jin Kim

    IPC分类号： C07K14/705 ,  C07K16/28 ,  C12N5/16

    CPC分类号： C07K14/70575 ,  C07K16/2875 ,  C07K2317/34

    摘要： A novel cytokine, designated Apo-2 ligand, which induces mammalian cell apoptosis is provided. The Apo-2 ligand is believed to be a member of the TNF cytokine family. Compositions including Apo-2 ligand chimeras, nucleic acid encoding Apo-2 ligand, and antibodies to Apo-2 ligand are also provided. Methods of using Apo-2 ligand to induce apoptosis and to treat pathological conditions such as cancer, are further provided.

    摘要翻译： 提供了诱导哺乳动物细胞凋亡的新型细胞因子，称为Apo-2配体。 Apo-2配体被认为是TNF细胞因子家族的成员。 还提供了包括Apo-2配体嵌合体，编码Apo-2配体的核酸和Apo-2配体的抗体的组合物。 进一步提供了使用Apo-2配体诱导细胞凋亡和治疗病理状况如癌症的方法。

    Monoclonal antibodies to human leukemia inhibitory factor
    42.
    发明授权
    Monoclonal antibodies to human leukemia inhibitory factor 失效
    人白血病抑制因子单克隆抗体

    公开(公告)号：US5688681A

    公开(公告)日：1997-11-18

    申请号：US258918

    申请日：1994-06-13

    申请人： Kyung Jin Kim

    发明人： Kyung Jin Kim

    IPC分类号： A61K38/00 ,  C07K16/24 ,  C12P21/08 ,  C12N5/20 ,  G01N33/53

    CPC分类号： C07K16/244 ,  A61K38/00 ,  C07K2317/74

    摘要： The invention relates to monoclonal antibodies to human leukemia inhibitory factor. The disclosed monoclonal antibodies are believed to recognize unique epitopes on hLIF and are useful in the treatment of conditions wherein the presence of hLIF causes or contributes to undesirable pathological effects, such as cachexia, dysregulated calcium metabolism, or excessive bone cell proliferation, and in the detection of hLIF, for example, in clinical samples or specimens.

    摘要翻译： 本发明涉及人白血病抑制因子的单克隆抗体。 所公开的单克隆抗体被认为在hLIF上识别出独特的表位，并且可用于治疗其中hLIF的存在引起或有助于不期望的病理学作用，例如恶病质，调节钙代谢或过度骨细胞增殖的病症，并且在 检测hLIF，例如临床样本或标本。

    Method for producing a biobutanol using a thiolase with improved activity
    47.
    发明授权
    Method for producing a biobutanol using a thiolase with improved activity 有权
    使用具有改善活性的硫解酶生产生物丁醇的方法

    公开(公告)号：US08357521B2

    公开(公告)日：2013-01-22

    申请号：US13253405

    申请日：2011-10-05

    申请人： Kyung Jin Kim

    发明人： Kyung Jin Kim

    IPC分类号： C12P7/16

    CPC分类号： C12N9/1029 ,  C12P7/16 ,  Y02E50/10

    摘要： The present invention relates to a modified thiolase protein with an improved activity, a polynucleotide encoding the modified protein, an expression vector including the polynucleotide, and a transformant, to a composition for producing a biobutanol including the thiolase with an improved activity or a cell expressing the thiolase, and to a method of producing the biobutanol.

    摘要翻译： 本发明涉及具有改善的活性的修饰的硫硫酸酶蛋白质，编码修饰蛋白质的多核苷酸，包含多核苷酸的表达载体和转化体，涉及用于生产包含具有改善的活性或表达细胞的细胞的硫解酶的生物丁醇的组合物 硫解酶，以及生产生物丁醇的方法。

    Mobile terminal and communication history providing method using the same
    48.
    发明授权
    Mobile terminal and communication history providing method using the same 有权
    移动终端和通信历史提供方法使用该方法

    公开(公告)号：US08351904B2

    公开(公告)日：2013-01-08

    申请号：US12427235

    申请日：2009-04-21

    申请人： Kyung Jin Kim ,  Jee Young Chun ,  Sae Kyu Park ,  Yong Man Park ,  Ji Hyun Kim

    发明人： Kyung Jin Kim ,  Jee Young Chun ,  Sae Kyu Park ,  Yong Man Park ,  Ji Hyun Kim

    IPC分类号： H04M1/725

    CPC分类号： H04L51/34 ,  H04L51/38

    摘要： A mobile terminal including a communication unit configured to provide a communication function including at least one of an outgoing communication function and an incoming communication function, a controller configured to acquire surrounding data including at least one of image data or sound data corresponding to a surrounding of where the communication function is performed, and to match the acquired surrounding data with communication information indicating a first party of the outgoing function or a second party of the incoming communication function, and a display unit configured to display a communication history including the communication information matched with the surrounding data. In addition, the controller is further configured to acquire the surrounding data selectively based on a) a manual operation of the terminal or b) automatically without user intervention.

    摘要翻译： 一种移动终端，包括：通信单元，被配置为提供包括传出通信功能和传入通信功能中的至少一个的通信功能;控制器，被配置为获取周围数据，所述控制器被配置为获取包括与周围环境对应的图像数据或声音数据中的至少一个 其中执行通信功能，并且将获取的周围数据与指示出站功能的第一方的通信信息或进入通信功能的第二方匹配;以及显示单元，被配置为显示包括匹配的通信信息的通信历史 与周围的数据。 此外，控制器还被配置为基于a）终端的手动操作或b）自动地获取周围数据而无需用户干预。

    Neurobiological method for measuring human intelligence and system for the same
    50.
    发明申请
    Neurobiological method for measuring human intelligence and system for the same 有权
    用于测量人体智力和系统的神经生物学方法

    公开(公告)号：US20100174171A1

    公开(公告)日：2010-07-08

    申请号：US12376799

    申请日：2007-08-09

    申请人： Kun Ho Lee ,  Yu Yong Choi ,  Kyung Jin Kim ,  Jong Min Lee

    发明人： Kun Ho Lee ,  Yu Yong Choi ,  Kyung Jin Kim ,  Jong Min Lee

    IPC分类号： A61B5/055

    CPC分类号： A61B5/16 ,  G01R33/4806 ,  G06F19/00

    摘要： The present invention relates to a method for measuring human intelligence using a neurobiogical model. The invention provides a method which enables neurometric IQ to be measured by processing the MRI and fMRI images of subjects to determine cortical thicknesses and brain activation levels, determining structural IQ (sIQ) and functional IQ (fIQ) from the cortical thicknesses and the brain activation levels, and using the structural IQ (sIQ) and the functional IQ (fIQ) as predictors to measure the neurometric IQ of the subject. According to the present invention, the concept of a neurometric IQ (nIQ) model is established and can assist in easily assessing individual differences in general cognitive ability. These results suggest that general cognitive ability can be explained by two different neural bases or traits: facilitation of neural circuits and accumulation of crystallized knowledge.

    摘要翻译： 本发明涉及一种使用神经生物学模型测量人类智力的方法。 本发明提供一种能够通过处理受试者的MRI和fMRI图像来测量神经测量IQ以确定皮层厚度和脑激活水平，从皮层厚度和脑激活确定结构性IQ（sIQ）和功能IQ（fIQ）的方法 水平，并使用结构性IQ（sIQ）和功能IQ（fIQ）作为预测因子来测量受试者的神经测量IQ。 根据本发明，建立了神经测量IQ（nIQ）模型的概念，并且可以帮助轻松评估一般认知能力中的个体差异。 这些结果表明，一般认知能力可以通过两种不同的神经基础或特征来解释：促进神经回路和结晶化知识的积累。