摘要:
An apparatus and method for providing electrostatic discharge protection for a disc drive read head. A pair of depletion mode MOSFETS, and a fuse associated with each are disposed between the read head output terminals. The MOSFETS are controlled to an “off” state for testing the preamplifier prior to assembly of the read head. After assembly of the head, a second pair of MOSFETS is gated to an “on” state to open the fuses and thus permit normal operation of the read head.
摘要:
The invention provides compounds of the formula (0) or salts or tautomers or N-oxides or solvates thereof for use in the prophylaxis or treatment of disease states and conditions such as cancers mediated by cyclin-dependent kinase and glycogen synthase kinase-3. In formula (0): X is a group R1-A-NR4— or a 5- or 6-membered carbocyclic or heterocyclic ring; A is a bond, SO2, C═O, NRg(C═O) or O(C═O) wherein Rg is hydrogen or C1-4 hydrocarbyl optionally substituted by hydroxy or C1-4 alkoxy; Y is a bond or an alkylene chain of 1, 2 or 3 carbon atoms in length; R1 is hydrogen; a carbocyclic or heterocyclic group having from 3 to 12 ring members; or a C1-8 hydrocarbyl group optionally substituted by one or more substituents selected from halogen (e.g. fluorine), hydroxy, C1-4 hydrocarbyloxy, amino, mono- or di-C1-4 hydrocarbylamino, and carbocyclic or heterocyclic groups having from 3 to 12 ring members, and wherein 1 or 2 of the carbon atoms of the hydrocarbyl group may optionally be replaced by an atom or group selected from O, S, NH, SO, SO2; R2 is hydrogen; halogen; C1-4 alkoxy (e.g. methoxy); or a C1-4 hydrocarbyl group optionally substituted by halogen (e.g. fluorine), hydroxyl or C1-4 alkoxy (e.g. methoxy); R3 is selected from hydrogen and carbocyclic and heterocyclic groups having from 3 to 12 ring members; and R4 is hydrogen or a C1-4 hydrocarbyl group optionally substituted by halogen (e.g. fluorine), hydroxyl or C1-4 alkoxy (e.g. methoxy).
摘要:
Described is a method for retrieving a user document using behavioral attributes associated with the user document. One or more relevant documents in a user library are determined in response to a text search of documents in the library. Each relevant document has a text relevance. A behavioral relevant is determined for each of the relevant documents based upon an associated behavioral attribute. A user relevance is determined for each of the relevant documents in response to the text relevance and the behavioral relevance of each relevant document. A list of relevant documents is generated and ordered according to user relevance.
摘要:
A method for separation of mixtures in fluidic systems through electrokinetic transport by use of nanochannels when the fluidic systems approach the size of an electrical double layer, thereby allowing separation based on charge. The disclosed apparatus comprises a T-chip with a nanochannel section. The method and apparatus are useful for separation of many molecular species, including peptides, proteins, and DNA.
摘要:
A system for automatically providing notifications to a user regarding interesting content, which automatically collects information regarding persons that are important to the user, as well as indications of important content sources. The important content sources are then monitored for actions performed by one of the important persons for the user, and notifications are generated to the user in the event that the important person performs an action on a document or other information item stored in the important content source. Important persons for a user may be determined through a communication application used by the user, such as an electronic mail program, instant messaging program, or the like, in response to indications of persons that the user has either sent messages to and/or received messages from. The notifications may be provided through the user's communication application, by electronic mail messages, instant messages, or the like. The notification may include a name, identifier, or other indication of the important person that performed the action on the important content source. Notifications may be provided to the user in response to any specific kind of action by the important persons on an important content source, such as create operations, modify operations, and/or delete operations.
摘要:
A composition comprising the reaction products of MaMHbMEcDdDHeDEfTgTHhTEiQj where M=R1R2R3SiO1/2; MH=R4R5H SiO1/2; ME=R6R7RESiO1/2; D=R8R9SiO2/2; DH=R10HSiO2/2; DE=R11RESiO2/2; T=R12SiO3/2; TH=HSiO3/2; TE=RESiO3/2; and Q=SiO4/2; where R1, R2, R3, R8, R9 and R12 are independently monovalent hydrocarbon radicals having from one to sixty carbon atoms; R4, R5 and R10 are independently monovalent hydrocarbon radicals having from one to sixty carbon atoms or hydrogen; R6, R7, R11 are independently monovalent hydrocarbon radicals having from one to sixty carbon atoms or RE; each RE is independently a monovalent hydrocarbon radical containing one or more oxirane moieties having from one to sixty carbon atoms; the stoichiometric subscripts a, b, c, d, e, f, g, h, i, and j are either zero or positive subject to the following limitations: a+b+c>1;b+e+h>1;c+f+i>1;b+e+h>c+f+i. In a preferred embodiment the reaction product of the present invention is a polyether siloxane copolymer network. In another preferred embodiment the reaction product of the present invention is a polyether siloxane copolymer network swollen with a volatile low molecular weight silicon containing compound. These compositions are useful for a variety of personal care compositions.
摘要:
A dental prosthesis is made by first forming a model of a patient's dentition. A three dimensional digital data corresponding to the surfaces of the model is then created. Based on this data, a three dimensional digital data file is then created substantially corresponding to the dental prosthesis to be manufactured. The three dimensional digital data of the dental prosthesis to be manufactured is next transmitted to automated prototyping equipment, and using the automated prototyping equipment, a wax pattern of the dental prosthesis is manufactured based upon this three dimensional digital data of the dental prosthesis. Finally, using this wax pattern in the lost wax investment casting process, the dental prosthesis is made. Prior to investment casting, marginal edges of the wax pattern are adjusted manually.
摘要:
A method for the preparation of a compound of formula ##STR1## wherein R is hydrogen or, respectively, a group of formula ##STR2## R.sub.1 is alkyl; Ar is optionally substituted aryl; and R.sub.3' and R.sub.3" are hydrogen, alkyl or phenyl, or R.sub.3' and R.sub.3" taken together with the carbon atom to which they are attached form cycloalkyl, or salt thereof, comprising acid facilitated acetalizing or ketalizing of a compound of formula ##STR3## wherein R.sub.3' and R.sub.3" are as defined above, and R.sub.4' and R.sub.4" are alkoxy, or taken together with the carbon atom to which they are attached form carbonyl, with a compound of formula ##STR4## wherein * represents an R chirality; R, R.sub.1 and Ar are as defined above, or salt thereof in isopropanol.