公开(公告)号：US08663314B2

公开(公告)日：2014-03-04

申请号：US13396088

申请日：2012-02-14

申请人： Mark Wood ,  Paul Norton ,  William Bertolino ,  F. Anthony Headley, Jr.

发明人： Mark Wood ,  Paul Norton ,  William Bertolino ,  F. Anthony Headley, Jr.

IPC分类号： A61F2/82

CPC分类号： A61F2/90 ,  A61F2/848 ,  A61F2210/0076 ,  A61F2220/0016

摘要： The present invention relates to stent structures having improved migration resistance. In particular, the invention relates to mesh stents, such as braided or twisted stent designs, where at least a portion of the stent is folded back over itself to form a multi-layered stent device. Such multi-layered portions provide for migration resistance, among other advantages.

摘要翻译： 本发明涉及具有改善的耐迁移性的支架结构。 特别地，本发明涉及网状支架，例如编织或扭曲支架设计，其中支架的至少一部分自身折回以形成多层支架装置。 除了其它的优点之外，这种多层部分提供了耐迁移性。

公开(公告)号：US20130226170A1

公开(公告)日：2013-08-29

申请号：US13781222

申请日：2013-02-28

申请人： Dane Seddon ,  Sean Fleury ,  Mark Wood ,  Peter Dayton

发明人： Dane Seddon ,  Sean Fleury ,  Mark Wood ,  Peter Dayton

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B18/14 ,  A61B18/1482 ,  A61B2017/003 ,  A61B2017/00305 ,  A61B2017/00314 ,  A61B2017/00323

摘要： Embodiments of the disclosure include devices and systems for using an end effector. In an embodiment, a medical device may include an articulation section. The articulation section may be operatively associated with an elongate articulation member configured to move the articulation section, wherein the articulation section can be configured to receive part of a conductive member. The medical device may also include an end effector. The end effector may include an electrode and a non-conductive section encasing a junction between the electrode and the conductive member, wherein the non-conductive section can be moveably coupled to the articulation section and can be fixedly coupled to the elongate articulation member.

公开(公告)号：US08466122B2

公开(公告)日：2013-06-18

申请号：US13235253

申请日：2011-09-16

申请人： James Heyes ,  Mark Wood ,  Alan Martin

发明人： James Heyes ,  Mark Wood ,  Alan Martin

IPC分类号： C12N15/11 ,  C07H21/02 ,  A61K9/127

CPC分类号： A61K47/44 ,  A61K9/1272 ,  A61K31/7088 ,  A61K31/7105 ,  A61K31/713 ,  A61K47/34 ,  C07C229/12 ,  C07C271/20

摘要： The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel cationic lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of a specific target protein at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.

摘要翻译： 本发明提供了将治疗剂递送至细胞的组合物和方法。 特别地，这些包括提供核酸的有效包封的新型阳离子脂质和核酸 - 脂质颗粒，并将包封的核酸在体内有效递送至细胞。 本发明的组合物是高度有效的，从而允许以相对低的剂量有效击倒特异性靶蛋白。 此外，与本领域已知的组合物和方法相比，本发明的组合物和方法毒性低，并提供更大的治疗指数。

公开(公告)号：US20110290783A1

公开(公告)日：2011-12-01

申请号：US12786499

申请日：2010-05-25

申请人： Joseph Geiger ,  Michael Gerdes ,  Troy Wilson ,  Mark Wood ,  Anthony Zymroz, JR.

发明人： Joseph Geiger ,  Michael Gerdes ,  Troy Wilson ,  Mark Wood ,  Anthony Zymroz, JR.

IPC分类号： H05B3/68 ,  F16M13/02

CPC分类号： F24C15/10 ,  F24C7/08

摘要： A domestic appliance includes a control panel and a control panel mounting bracket which includes a frame shaped for being installed on a surface panel of a domestic appliance. The surface panel has an opening therein for receiving the frame. The frame has an open portion for receiving a control mount adhered over the open portion. The surface panel has a top surface and a bottom surface, and the frame has a main securing member having at least one tab extending therefrom. The tab is bendable along a line off-set from vertical such that when the tab is bent, it bears against the bottom surface of the surface panel to urge the frame against the surface panel.

摘要翻译： 家用电器包括控制面板和控制面板安装支架，该支架包括形状为安装在家用电器的表面面板上的框架。 表面板在其中具有用于接收框架的开口。 框架具有开口部分，用于接收粘附在开口部分上的控制装置。 表面板具有顶表面和底表面，并且框架具有主固定构件，其具有从其延伸的至少一个突出部。 标签可以沿着垂直偏离的线弯曲，使得当突片弯曲时，该突片抵靠在表面板的底表面上以将框架推靠在表面板上。

公开(公告)号：US20090312834A1

公开(公告)日：2009-12-17

申请号：US12483488

申请日：2009-06-12

申请人： Mark Wood ,  Paul Norton ,  William Bertolino ,  F. Anthony Headley, JR.

发明人： Mark Wood ,  Paul Norton ,  William Bertolino ,  F. Anthony Headley, JR.

IPC分类号： A61F2/06

CPC分类号： A61F2/90 ,  A61F2/848 ,  A61F2210/0076 ,  A61F2220/0016

摘要： The present invention relates to stent structures having improved migration resistance. In particular, the invention relates to mesh stents, such as braided or twisted stent designs, where at least a portion of the stent is folded back over itself to form a multi-layered stent device. Such multi-layered portions provide for migration resistance, among other advantages.

摘要翻译： 本发明涉及具有改善的耐迁移性的支架结构。 特别地，本发明涉及网状支架，例如编织或扭曲支架设计，其中支架的至少一部分自身折回以形成多层支架装置。 除了其它的优点之外，这种多层部分提供了耐迁移性。

公开(公告)号：US20090287052A1

公开(公告)日：2009-11-19

申请号：US12467947

申请日：2009-05-18

申请人： Michael Devon Amos ,  Jason Weiner ,  Mark Wood

发明人： Michael Devon Amos ,  Jason Weiner ,  Mark Wood

IPC分类号： A61B1/00

CPC分类号： A61B1/018 ,  A61B1/0008 ,  A61B1/00137 ,  A61B1/2676

摘要： Endoscope assemblies and methods for making and using the same. An example endoscope assembly may include an endoscope having a channel formed therein and a port that provides access to the channel, a cap disposed on the port, and an attachment assembly coupled to the cap. The attachment assembly may include a base and one or more arms extending from the base. A locking member may be coupled to at least one of the one or more arms.

摘要翻译： 内镜组件及其使用方法。 示例性内窥镜组件可以包括具有形成在其中的通道的内窥镜和提供对通道的通路的端口，设置在端口上的盖以及联接到盖的附接组件。 附接组件可以包括基部和从基部延伸的一个或多个臂。 锁定构件可以联接到一个或多个臂中的至少一个臂。

公开(公告)号：US20090182194A1

公开(公告)日：2009-07-16

申请号：US12314500

申请日：2008-12-11

申请人： Mark Wood ,  John Hutchins

发明人： Mark Wood ,  John Hutchins

IPC分类号： A61B1/018

CPC分类号： A61B1/018 ,  A61B1/0008 ,  A61B1/00098 ,  A61B1/2736

摘要： Embodiments of the invention include a medical device for accessing a patient's body portion and used for diagnosis and treatment of medical conditions. Embodiments of the invention may include a particular endoscopic positioning mechanism for placing an endoscope and an additional treatment device within desired body portions in order to assist in diagnosis and treatment of anatomical diseases and disorders. In particular, a medical device according to an embodiment of the invention includes a positioning mechanism configured to maintain the relative position of a treatment instrument with respect to an underlying endoscope during a treatment procedure.

摘要翻译： 本发明的实施例包括用于访问患者身体部分并用于诊断和治疗医疗状况的医疗装置。 本发明的实施例可以包括特定的内窥镜定位机构，用于将内窥镜和附加治疗装置放置在期望的身体部分内，以帮助诊断和治疗解剖疾病和病症。 具体地，根据本发明的实施例的医疗装置包括定位机构，其构造成在治疗过程期间保持治疗器具相对于下面的内窥镜的相对位置。

公开(公告)号：US20080009934A1

公开(公告)日：2008-01-10

申请号：US11762334

申请日：2007-06-13

申请人： Eric Schneider ,  Mark Wood ,  Gary J. Leanna ,  Gary Jordan ,  James Weldon ,  Jason Weiner

发明人： Eric Schneider ,  Mark Wood ,  Gary J. Leanna ,  Gary Jordan ,  James Weldon ,  Jason Weiner

IPC分类号： A61F2/06

CPC分类号： A61F2/95 ,  A61F2002/9583

摘要： A device, such as a catheter, for intraluminally delivering a distensible stent includes a first elongate tubular member having a proximal end and a distal end; a band circumferentially disposed over at least a circumferential portion of the first tubular member at the proximal end, the band having at least one projection for releasably engaging a portion of a radially distensible stent; and a second elongate tubular member slidably disposed over the first tubular member and the band. Desirably, the at least one projection is a low-profile, lobate-projection. shaped projection. The band may include two opposed projections, where the two opposed projections may be circumferentially disposed at about 180° from one and the other. Desirably, the band includes a metal, for example, stainless steel.

摘要翻译： 用于腔内递送可扩张支架的诸如导管的装置包括具有近端和远端的第一细长管状构件; 在所述近端处沿周向设置在所述第一管状构件的至少周向部分上的带，所述带具有用于可释放地接合径向扩张的支架的一部分的至少一个突起; 以及可滑动地设置在所述第一管状构件和所述带上的第二细长管状构件。 期望地，至少一个突起是低调的叶状突起。 形状投影。 带可以包括两个相对的突起，其中两个相对的突出部可以沿着圆周方向彼此大约180°设置。 期望地，带包括金属，例如不锈钢。

公开(公告)号：US20070265499A1

公开(公告)日：2007-11-15

申请号：US11430067

申请日：2006-05-09

申请人： Mark Wood ,  Gary Leanna

发明人： Mark Wood ,  Gary Leanna

IPC分类号： A61B1/00

CPC分类号： A61B1/00073 ,  A61B1/00091 ,  A61B1/00101 ,  A61B1/0016 ,  A61B1/00177 ,  A61B1/00181 ,  A61B1/00183 ,  A61B1/0052 ,  A61B1/018 ,  A61B1/2736 ,  A61B1/313 ,  A61M25/0133 ,  A61M25/0147

摘要： Embodiments of the invention include a medical device for accessing a patient's body portion and used for diagnosis and treatment of medical conditions. Embodiments of the invention may include a particular endoscopic positioning mechanism for placing an endoscope and an additional treatment device within desired body portions in order to assist in diagnosis and treatment of anatomical diseases and disorders. In particular, a medical device according to an embodiment of the invention may include an outer flexible tube and a positioning mechanism configured for rotating one portion of the flexible tube relative to another portion of the flexible tube.

摘要翻译： 本发明的实施例包括用于访问患者身体部分并用于诊断和治疗医疗状况的医疗装置。 本发明的实施例可以包括特定的内窥镜定位机构，用于将内窥镜和附加治疗装置放置在期望的身体部分内，以帮助诊断和治疗解剖疾病和病症。 特别地，根据本发明的实施例的医疗装置可以包括外部柔性管和定位机构，该定位机构构造成用于相对于柔性管的另一部分旋转柔性管的一部分。

公开(公告)号：US20070240199A1

公开(公告)日：2007-10-11

申请号：US11575266

申请日：2005-11-02

申请人： Mark Wood

发明人： Mark Wood

IPC分类号： G07C9/00

CPC分类号： G07C9/00119

摘要： An identification label (10) includes a microprocessor (38), a display (14), a keyboard (16) and a memory means for storing a security code and a plurality of editable screens of text, the label (10) being arranged to wake up from a sleep mode and display a start screen (50) selected from a plurality of screens of text for a predetermined period of time when the label is activated, and in which preselection of the screen of text be displayed and editing of screens of editable text can be effected only after inputting a security code via the keyboard (10).

摘要翻译： 识别标签（10）包括微处理器（38），显示器（14），键盘（16）和用于存储安全码和多个可编辑文本屏幕的存储装置，所述标签（10）布置成 从休眠模式唤醒，并且在标签被激活的预定时间段中显示从多个文本屏幕中选择的开始画面（50），并且其中显示文本画面的预选并编辑画面 只有通过键盘（10）输入安全码后才可以实现可编辑文本。