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公开(公告)号：US07517312B2
公开(公告)日：2009-04-14
申请号：US10938155
申请日：2004-09-10
IPC分类号： A61N1/362
CPC分类号： A61H99/00 , A61H9/0078 , A61H2201/163 , A61H2201/1642 , A61H2205/084 , A61H2205/086 , A61H2205/10 , A61H2205/106 , A61H2205/108
摘要： A method for treating patients suffering from left ventricular dysfunction, exhibited by a left ventricular ejection fraction (LVEF) less than normal, is disclosed. The method involves applying, during diastole, for a time period of about one hour, about five days each week for at least about seven weeks, an incrementally increasing therapeutic pressure to the patients' lower extremities, from the calves through the thighs and the buttocks. The hourly treatments are carried out at incrementally increasing peak diastolic/systolic pressure ratios (D/S Ratios) in the range of about 0.4:1 up to about 0.6:1 and thereafter at a D/S Ratio in the range of 0.5:1 to 1:1 for each consecutive hourly treatment, with the proviso that the average D/S Ratio over the entire treatment regimen does not exceed about 0.9:1.
摘要翻译： 公开了一种治疗患有左心室功能障碍的患者的方法，该方法由左心室射血分数（LVEF）显示小于正常值。 该方法包括在舒张期期间在约1小时，每周约5天的时间内施用至少约7周，对患者的下肢的治疗压力逐渐增加，从小腿通过大腿和臀部 。 小时处理是以递增增加的峰值舒张压/收缩压比（D / S比）在约0.4:1至约0.6:1的范围内进行的，此后以0.5:1的D / S比 每次连续小时治疗为1：1，条件是整个治疗方案的平均D / S比不超过约0.9：1。
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公开(公告)号：US07244225B2
公开(公告)日：2007-07-17
申请号：US10681812
申请日：2003-10-07
IPC分类号： A61N1/362
CPC分类号： A61H9/0078 , A61H31/006 , A61H2201/1621 , A61H2201/163 , A61H2201/1642 , A61H2201/5002 , A61H2205/083 , A61H2205/084 , A61H2205/086 , A61H2205/10 , A61H2205/106 , A61H2205/108
摘要： Circulatory assistance is provided in a non-invasive procedure safely and effectively using a microprocessor of an external counter pulsation device programmed to control the actuation of any or all of a plurality of valves, each of which is mounted on and in fluid communication with one of a plurality of individual inflatable bladders disposed in pockets within cuffs encasing the calves, thighs, buttocks, abdomen and/or chest of a person and an optional valve in fluid communication with the person's airway, in any desired sequence or order, toward the heart or toward the feet, either during diastole or systole, at desired inception times during the cardiac cycle, for selected durations and at chosen pressures, for treating a variety of cardiac, non-cardiac and circulatory conditions.
摘要翻译： 以非侵入性的方法提供循环辅助，安全有效地使用外部计数器脉动装置的微处理器，其被编程为控制多个阀中的任何一个或全部阀的致动，每个阀被安装在 多个单独的充气气囊，其以任何期望的顺序或顺序排列成包围人的小腿，大腿，臀部，腹部和/或胸部以及与所述人的气道流体连通的可选阀的口袋内的口袋， 在舒张期或收缩期间，在心脏周期期间的所需起始时间，选定的持续时间和选定的压力下，用于治疗各种心脏，非心脏和循环条件。
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公开(公告)号：US6080148A
公开(公告)日：2000-06-27
申请号：US751552
申请日：1996-11-18
CPC分类号： A61B18/22 , A61B2017/0019 , A61B2017/00977
摘要： A variable pulse width lasing device for selectively reducing the amount of laser energy provided during a surgical procedure is described. The device includes a central processing unit, a laser resonator, pulse width detector and a pulse modulator. The central processing unit provides a switch activation command to the modulator. The modulator also receives a laser pulse produced by the laser resonator which has an initial pulse width and a wavelength which is compatible for transmission through an optical fiber. The modulator varies the width of the laser pulse for providing an output pulse at a selected pulse width and energy level.
摘要翻译： 描述了用于选择性地减少在外科手术期间提供的激光能量的可变脉冲宽度激光装置。 该装置包括中央处理单元，激光谐振器，脉冲宽度检测器和脉冲调制器。 中央处理单元向调制器提供开关激活命令。 调制器还接收由激光谐振器产生的激光脉冲，其具有初始脉冲宽度和与通过光纤的透射兼容的波长。 调制器改变激光脉冲的宽度，以便以选定的脉冲宽度和能级提供输出脉冲。
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公开(公告)号：US4418688A
公开(公告)日：1983-12-06
申请号：US280247
申请日：1981-07-06
申请人： Marvin P. Loeb
发明人： Marvin P. Loeb
CPC分类号： A61B1/0051 , A61B1/00082 , A61B1/00165 , A61B18/245 , A61B1/015 , A61B1/07 , A61B2017/22051 , A61B2018/2238 , A61B2090/306 , A61B2090/3614
摘要： A fiber optic microcatheter device is provided with a conduit directing system to tilt the distal end of an internal conduit with respect to an external tube held in a lumen by expanding the diameter of an elastic zone on the external tube. Within the internal conduit are viewing and illumination fiber optic bundles which permit viewing within the lumen. A laser light transmitting fiber within the internal conduit may be aimed at a site within the lumen by tilting the distal end of the internal conduit. Also provided are tubes for flushing and vacuum to provide clear viewing within the lumen and to remove debris.
摘要翻译： 光纤微导管装置设置有导管引导系统，用于通过扩大外管上的弹性区的直径来相对于保持在内腔中的外管倾斜内导管的远端。 在内部导管内是观察和照明光纤束，其允许在内腔内观察。 通过倾斜内部导管的远端，内部导管内的激光传输光纤可以瞄准内腔内的部位。 还提供了用于冲洗和真空的管以在内腔内提供清晰的观察并去除碎屑。
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公开(公告)号：US4403984A
公开(公告)日：1983-09-13
申请号：US218710
申请日：1980-12-22
申请人： Stephen R. Ash , Marvin P. Loeb
发明人： Stephen R. Ash , Marvin P. Loeb
CPC分类号： A61B5/14528 , A61B5/14532 , A61M5/1723
摘要： A system is disclosed for demand-based administration of insulin which utilizes a change in a physical property of a patient's body fluid as an indicator that a change in the body fluid glucose level has occurred and that an appropriate amount of insulin should be supplied to the patient. Body fluid osmolality or one of its colligative properties are particularly suitable for this purpose. A second sensor for measuring such properties as electrical conductivity may be added to detect changes in osmolality caused by such factors as dehydration. Insulin can be delivered to the patient from an extracorporeal source by means of a dual lumen catheter. One lumen of the catheter provides a passageway for the insulin dose and the other lumen provides a passageway through which a replaceable sensors can be introduced into or removed from the patient's body. In the alternative, the entire insulin administration system can be implanted into the patient.
摘要翻译： 公开了一种基于需求的胰岛素给药系统，其利用患者体液的物理特性的变化作为体液葡萄糖水平的变化已经发生的指标，并且应该将适当量的胰岛素供应给 患者。 体液重量摩尔渗透压浓度或其碰撞性质之一特别适合于此目的。 可以添加用于测量诸如导电性的性质的第二传感器以检测由诸如脱水等因素引起的渗透压的变化。 胰岛素可以通过双腔导管从体外来源输送给患者。 导管的一个内腔提供用于胰岛素剂量的通道，另一个内腔提供通道，通过该通道将可更换的传感器引入患者的身体或从病人的身体移除。 在替代方案中，整个胰岛素给药系统可以植入患者体内。
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公开(公告)号：US4378016A
公开(公告)日：1983-03-29
申请号：US283610
申请日：1981-07-15
申请人： Marvin P. Loeb
发明人： Marvin P. Loeb
CPC分类号： A61F2/022
摘要： An artifical endocrine gland for supplying a hormone to a patient including an implantable housing placed in the body and having an impermeable extracorpeal segment and a semipermeable subcutaneous segment. A replaceable envelope containing live hormone-producing cells such as pancreatic islet cells is then removably positioned in the housing to provide hormones to the patient.
摘要翻译： 用于向患者提供激素的人造内分泌腺，包括放置在体内的可植入的壳体，并具有不可渗透的旁分期和半透皮皮下段。 然后将包含活的激素产生细胞如胰岛细胞的可替换的包膜可拆卸地定位在外壳中以向患者提供激素。
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