公开(公告)号：US11806456B2

公开(公告)日：2023-11-07

申请号：US16691686

申请日：2019-11-22

Applicant: Medtronic, Inc.

Inventor： Christopher M. Hobot ,  Martin T. Gerber

IPC: A61M1/28

CPC classification number: A61M1/284 ,  A61M1/285 ,  A61M2205/33 ,  A61M2205/3334 ,  A61M2230/005 ,  A61M2230/201 ,  A61M2230/65

Abstract: The invention relates to devices, systems, and methods for performing a precision or personalized Peritoneal Dialysis (PD) therapy session or cycle based on dialysis adequacy measurements in patients undergoing peritoneal dialysis treatment. The settings for the precision peritoneal dialysis therapy session can be obtained using one or more flow sensors and one or more uremic solute sensors that measure the uremic solute concentration and volume of the peritoneal dialysate removed from the patient. The desired dialysis adequacy for a specific patient, group of patients, or class of patients, can then be calculated based on the measured peritoneal dialysate concentration and volume. Using the calculated dialysis adequacy, the system and methods can then set one or more peritoneal dialysis parameters for subsequent cycles or sessions.

公开(公告)号：US20220323661A1

公开(公告)日：2022-10-13

申请号：US17224256

申请日：2021-04-07

Applicant: Medtronic, Inc.

Inventor： Kaustubh R. Patil ,  Sukalyan Dutta ,  Christopher M. Hobot ,  Bryant J. Pudil

IPC: A61M1/16

Abstract: The disclosure relates to systems and methods for increasing the functional capabilities of a sorbent-based dialysis system. The systems and methods allow for the mode of operation of the dialysis system to be switched between single pass mode and a sorbent based multi-pass mode by controlling an amount of water added to the dialysate between 0% to 100% of the dialysate flow rate.

公开(公告)号：US11213616B2

公开(公告)日：2022-01-04

申请号：US16458336

申请日：2019-07-01

Applicant: Medtronic, Inc.

Inventor： Sukalyan Dutta ,  Bryant J. Pudil ,  Krishnaraja Nellikunje ,  Christopher M. Hobot ,  Kanjimpuredathil Muralikrishna Menon

IPC: A61M1/16 ,  B01J20/02

Abstract: The invention relates to devices, systems, and methods for mixing one or more solutions to generate a recharge solution having specified concentrations of a sodium salt and acid for recharging and disinfecting zirconium phosphate in reusable sorbent modules. The devices, systems, and methods can generate a recharge solution by a sorbent recharger that is introduced through the sorbent module to recharge and to disinfect the zirconium phosphate.

公开(公告)号：US20210187481A1

公开(公告)日：2021-06-24

申请号：US17197665

申请日：2021-03-10

Applicant: Medtronic, Inc.

Inventor： Christopher M. Hobot ,  Bryant J. Pudil

IPC: B01J20/34 ,  A61M1/16 ,  B01J20/28 ,  B01J49/57 ,  B01J49/08 ,  B01J49/07 ,  A61L2/00 ,  B01D15/00 ,  B01J20/02 ,  B01J20/06 ,  C01B25/37 ,  C01G25/02

Abstract: The invention relates to devices, systems, and methods for conditioning a zirconium oxide sorbent module for use in dialysis after recharging. The devices, systems, and methods can provide for conditioning and recharging of zirconium oxide in a single system, or in separate systems.

公开(公告)号：US11013843B2

公开(公告)日：2021-05-25

申请号：US15914791

申请日：2018-03-07

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  A61M1/16 ,  A61B5/145 ,  A61B5/00 ,  G01N21/78 ,  G01N21/80 ,  G01N21/77

Abstract: The invention relates to a testing system and related methods for detecting peritonitis or infection in peritoneal dialysate removed from a patient. The testing system can include a fluid sensor apparatus in a fluid line of a peritoneal dialysis cycler through which spent peritoneal dialysate can be pumped. The fluid sensor apparatus can detect one or more markers associated with peritonitis or infection.

公开(公告)号：US10960381B2

公开(公告)日：2021-03-30

申请号：US15958337

申请日：2018-04-20

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Christopher M. Hobot

IPC: B01J20/34 ,  B01J20/02 ,  A61M1/16 ,  A61L2/18

Abstract: The invention relates to systems and methods for disinfecting, recharging, and conditioning zirconium phosphate in a reusable sorbent module. The systems and methods provide for reuse of a zirconium phosphate sorbent module after dialysis.

公开(公告)号：US10888648B2

公开(公告)日：2021-01-12

申请号：US15219187

申请日：2016-07-25

Applicant: Medtronic, Inc.

Inventor： David B. Lura ,  Christopher M. Hobot ,  Martin T. Gerber ,  Thomas E. Meyer

IPC: A61M1/36 ,  A61M1/16

Abstract: The invention relates to devices, systems, and methods for priming, disinfecting, and preparing dialysate and related fluids for use in dialysis. The dialysate and related fluids can be prepared from solutes obtained from infusate containers seated in an infusate caddy. The infusate caddy can be removably positioned in a receiving compartment of a dialysis machine. Similarly, the infusate containers containing the necessary solutes for preparing the dialysate and related fluids can also be removably positioned in the infusate caddy.

公开(公告)号：US20210001307A1

公开(公告)日：2021-01-07

申请号：US17023834

申请日：2020-09-17

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/28 ,  B01D15/08 ,  A61M1/16

Abstract: A sorbent pouch for use in sorbent dialysis. The sorbent pouch allows for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouch.

公开(公告)号：US20200086297A1

公开(公告)日：2020-03-19

申请号：US16436066

申请日：2019-06-10

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Christopher M. Hobot ,  Martin T. Gerber

IPC: B01J20/34 ,  A61M1/16 ,  B01J20/02 ,  B01J20/06

Abstract: The invention relates to devices, systems, and methods for precision recharging of sorbent materials in a sorbent module. The devices, systems, and methods use sensor-based analysis of an effluent of the sorbent module during recharging to set recharge parameters used in recharging the sorbent material.

公开(公告)号：US20200029868A1

公开(公告)日：2020-01-30

申请号：US16371155

申请日：2019-04-01

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Christopher M. Hobot ,  Martin T. Gerber

IPC: A61B5/145 ,  A61B5/00

Abstract: The invention relates to devices, systems, and methods for estimating a patient BUN level prior to a dialysis session based on data received when introducing an ammonium removal solution through a zirconium phosphate sorbent module. The systems and methods can introduce an ammonia removal solution and determine an ammonia content of the ammonium removal solution effluent to estimate the patient pre-dialysis BUN level.