公开(公告)号：US20160279424A1

公开(公告)日：2016-09-29

申请号：US14712519

申请日：2015-05-14

Applicant: Medtronic, Inc.

Inventor： Wade M Demmer

IPC: A61N1/378 ,  A61N1/365

CPC classification number: A61N1/378 ,  A61N1/365 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3688 ,  A61N1/3708

Abstract: An implantable medical device includes circuitry for generating and delivering electrical stimulation therapy. A power source is included in the implantable medical device for storage of the energy for the stimulation therapy. Techniques and circuits are provided for minimizing energy losses associated with the storage of the stimulation therapy energy. The implantable medical device circuitry includes charging circuitry that is operated in at least a first mode and a second mode, such that the charging circuit is operable in one of the at least first and second modes based on whether an intrinsic cardiac event is detected. The charging circuit is operable to withhold charging the output capacitor in the first mode until a given cardiac cycle elapses without a sensed intrinsic cardiac event.

Abstract translation: 可植入医疗装置包括用于产生和递送电刺激疗法的电路。 可植入医疗装置中包括电源，用于储存用于刺激疗法的能量。 技术和电路被提供用于最小化与刺激治疗能量的储存相关联的能量损失。 可植入医疗装置电路包括以至少第一模式和第二模式操作的充电电路，使得根据是否检测到内在心脏事件，充电电路可操作于至少第一和第二模式之一。 充电电路可操作以在第一模式中对输出电容器进行保持充电，直到经过给定的心动周期而没有感测到的内在心脏事件。

公开(公告)号：US20160129263A1

公开(公告)日：2016-05-12

申请号：US14538486

申请日：2014-11-11

Applicant: Medtronic, Inc.

Inventor： Wade M Demmer ,  Todd J Sheldon

IPC: A61N1/37 ,  A61N1/375 ,  A61N1/365

CPC classification number: A61N1/3702 ,  A61N1/3627 ,  A61N1/365 ,  A61N1/36507 ,  A61N1/37205 ,  A61N1/3756

Abstract: In some examples, a leadless pacing device (hereinafter, “LPD”) is configured for implantation in a ventricle of a heart of a patient, and is configured to switch between an atrio-ventricular synchronous pacing mode and an asynchronous ventricular pacing mode in response to detection of one or more sensing events, which may be, for example, undersensing events. In some examples, an LPD is configured to switch from a sensing without pacing mode to an atrio-ventricular synchronous pacing mode in response to determining, for a threshold number of cardiac cycles, a ventricular depolarization was not detected within a ventricular event detection window that begins at an atrial activation event.

Abstract translation: 在一些示例中，无引线起搏装置（以下称为“LPD”）被配置用于植入患者心脏的心室中，并且被配置为响应于心房间同步起搏模式和异步心室起搏模式之间的切换 以检测一个或多个感测事件，其可以是例如不足感的事件。 在一些示例中，响应于确定对于阈值数量的心动周期，在心室事件检测窗口内未检测到心室去极化，LPD被配置为从不具有起搏模式的感测切换到心室同步起搏模式 从心房激活事件开始。

公开(公告)号：US20160114168A1

公开(公告)日：2016-04-28

申请号：US14821141

申请日：2015-08-07

Applicant: Medtronic, Inc.

Inventor： Wade M Demmer ,  Todd J. Sheldon ,  Margaret G Guo

IPC: A61N1/365 ,  A61B5/04

CPC classification number: A61N1/36592 ,  A61B5/04017 ,  A61N1/3704

Abstract: A pacemaker implantable in a chamber of a patient's heart is configured to produce a filtered cardiac electrical signal by filtering a raw cardiac signal by an adjustable filter of a sensing module of the pacemaker. The sensing module is configured to receive the raw cardiac electrical signal comprising R-waves, T-waves and P-waves via electrodes coupled to the sensing module. The pacemaker is further configured to determine if the T-waves are distinct from the P-waves in the filtered cardiac electrical signal and adjust the filter to increase a difference between a feature of the P-waves and a feature of the T-waves in the filtered cardiac signal when the T-waves are not distinct from the P-waves.

Abstract translation: 可植入患者心脏的室中的起搏器被配置为通过由起搏器的感测模块的可调节过滤器过滤原始心脏信号来产生过滤心电信号。 感测模块​​被配置为通过耦合到感测模块的电极来接收包括R波，T波和P波的原始心电信号。 起搏器进一步被配置为确定T波是否与滤波心电信号中的P波不同，并调整滤波器以增加P波特征与T波特征之间的差异 当T波不与P波不同时，滤波后的心脏信号。

公开(公告)号：US09042984B2

公开(公告)日：2015-05-26

申请号：US14305722

申请日：2014-06-16

Applicant: Medtronic, Inc.

Inventor： Wade M Demmer ,  Karen J Kleckner ,  Paul A Belk

IPC: A61N1/362 ,  A61N1/365

CPC classification number: A61N1/36514 ,  A61N1/36507 ,  A61N1/36592

Abstract: Cardiac pacing methods for an implantable single chamber pacing system, establish an offset rate for pacing at a predetermined decrement from either a baseline rate (i.e. dictated by a rate response sensor), or an intrinsic rate. Pacing maintains the offset rate until x of y successive events are paced events, at which time the offset rate is switched to the baseline rate for pacing over a predetermined period of time. Following the period, if an intrinsic event is not immediately detected, within the interval of the offset rate, the rate is switched back to baseline for pacing over an increased period of time. Some methods establish a preference rate, between the offset and baseline rates, wherein an additional criterion, for switching from the offset rate to the baseline rate, is established with respect to the preference rate.

Abstract translation: 用于可植入单室起搏系统的心脏起搏方法，以基线速率（即由速率响应传感器指定）或内在速率以预定减量建立起搏偏移率。 起搏维持偏移率，直到y个连续事件的x为起搏事件，此时偏移速率被切换到预定时间段内的起搏基准速率。 在该期间之后，如果不立即检测到固有事件，则在偏移率的间隔内，速率将在增加的时间段内切换回基线。 一些方法在偏移和基线速率之间建立偏好率，其中针对偏好率建立用于从偏移率转换到基线速率的附加标准。

公开(公告)号：US20150119950A1

公开(公告)日：2015-04-30

申请号：US14063766

申请日：2013-10-25

Applicant: Medtronic, Inc.

Inventor： Wade M Demmer ,  Todd J Sheldon ,  Robert W Stadler ,  Xusheng Zhang

IPC: A61N1/37 ,  A61N1/36

CPC classification number: A61N1/3712 ,  A61N1/3601 ,  A61N1/36114 ,  A61N1/371

Abstract: A medical device system performs a method for determining pacing threshold data. Signals are received from a cardiac capture sensor and a phrenic nerve stimulation sensor. A cardiac capture threshold is determined from the cardiac capture sensor signal and a phrenic nerve stimulation threshold is determined from the phrenic nerve stimulation sensor signal for multiple pacing electrode vectors.

Abstract translation: 医疗装置系统执行用于确定起搏阈值数据的方法。 从心脏捕获传感器和膈神经刺激传感器接收信号。 从心脏捕获传感器信号确定心脏捕获阈值，并且从多个起搏电极载体的膈神经刺激传感器信号确定膈神经刺激阈值。

公开(公告)号：US08755884B2

公开(公告)日：2014-06-17

申请号：US13932782

申请日：2013-07-01

Applicant: Medtronic, Inc.

Inventor： Wade M Demmer ,  Karen J Kleckner ,  Paul A Belk

IPC: A61N1/362

CPC classification number: A61N1/36514 ,  A61N1/36507 ,  A61N1/36592

Abstract: Cardiac pacing methods for an implantable single chamber pacing system, establish an offset rate for pacing at a predetermined decrement from either a baseline rate (i.e. dictated by a rate response sensor), or an intrinsic rate. Pacing maintains the offset rate until x of y successive events are paced events, at which time the offset rate is switched to the baseline rate for pacing over a predetermined period of time. Following the period, if an intrinsic event is not immediately detected, within the interval of the offset rate, the rate is switched back to baseline for pacing over an increased period of time. Some methods establish a preference rate, between the offset and baseline rates, wherein an additional criterion, for switching from the offset rate to the baseline rate, is established with respect to the preference rate.

Abstract translation: 用于可植入单室起搏系统的心脏起搏方法，以基线速率（即由速率响应传感器指定）或内在速率以预定减量建立起搏偏移率。 起搏维持偏移率，直到y个连续事件的x为起搏事件，此时偏移速率被切换到预定时间段内的起搏基准速率。 在该期间之后，如果不立即检测到固有事件，则在偏移率的间隔内，速率将在增加的时间段内切换回基线。 一些方法在偏移和基线速率之间建立偏好率，其中针对偏好率建立用于从偏移率转换到基线速率的附加标准。