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公开(公告)号：US20120046332A1
公开(公告)日：2012-02-23
申请号：US13211715
申请日：2011-08-17
IPC分类号： A61K31/381 , A61K31/4025 , A61P27/02 , A61K31/4015
CPC分类号： A61K31/381 , A61K9/0048 , A61K9/0051 , A61K31/4015 , A61K31/4025 , A61K31/539 , A61K31/559 , A61K2300/00
摘要： Disclosed herein are compositions and methods for treating corneal haze. Compositions and methods of use comprise therapeutically effective amounts of compounds that agonize the EP2 and/or EP4 receptor. Administration of the disclosed compounds can prevent and treat corneal haze development.
摘要翻译： 本文公开了治疗角膜混浊的组合物和方法。 组合物和使用方法包括治疗有效量的激动EP2和/或EP4受体的化合物。 所公开的化合物的施用可以预防和治疗角膜混浊发展。
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42.发明申请公开(公告)号：US20120035148A1
公开(公告)日：2012-02-09
申请号：US13236432
申请日：2011-09-19
申请人： Scott M. Whitcup
发明人： Scott M. Whitcup
IPC分类号： A61K31/573 , A61P27/02
CPC分类号： A61K9/0024 , A61K9/0048 , A61K9/0051 , A61K31/44 , A61K31/56 , A61K31/57 , A61K31/573 , A61K31/575 , A61K31/58 , A61K45/06 , A61K47/34 , A61K47/38 , Y10S514/912
摘要： Compositions, and methods of using such compositions, useful for placement, for example injection, into the interior of human or animal eyes are provided. Such compositions include a therapeutic component, such as one or more corticosteroids, a biocompatible polymeric component, and a solvent component.
摘要翻译： 提供了组合物和使用这种组合物的方法，其用于将人体或动物眼睛的内部放置，例如注射。 这样的组合物包括治疗组分，例如一种或多种皮质类固醇，生物相容性聚合物组分和溶剂组分。
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公开(公告)号：US20100317595A1
公开(公告)日：2010-12-16
申请号：US12683841
申请日：2010-01-07
摘要： The present invention is directed to compositions and methods for stimulating the growth of nails and cuticles in a mammal, including humans. The compositions may be administered topically to the nail bed, nail matrix and cuticle in an amount effective to increase nail growth and thicken, strengthen and smooth the nail. The composition is also effective in strengthening and growing nails, including fingernails and toenails.
摘要翻译： 本发明涉及用于刺激哺乳动物（包括人）中指甲和角质层生长的组合物和方法。 组合物可以局部施用于甲床，指甲基质和角质层，其量可有效增加指甲生长并增厚，加强和平滑指甲。 组合也有效地加强和增长指甲，包括指甲和脚趾甲。
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44.发明授权公开(公告)号：US07728034B2
公开(公告)日：2010-06-01
申请号：US11326264
申请日：2006-01-05
CPC分类号： A61K31/381 , A61K31/00 , A61K31/136 , A61K31/235 , A61K31/4439
摘要： The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.
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45.发明授权Blocking cell adhesion molecules and treating animals with ocular inflammation 失效阻断细胞粘附分子并用眼部炎症治疗动物
公开(公告)号：US5597567A
公开(公告)日：1997-01-28
申请号：US192198
申请日：1994-02-04
IPC分类号： A61K39/395 , A61K38/00 , A61K39/40 , A61K39/42 , A61K39/44 , A61P29/00 , C07K16/28 , A61K39/00
CPC分类号： C07K16/2854 , C07K16/2821 , C07K16/2845 , A61K38/00
摘要： The present invention relates, in general, to a method of blocking of cell adhesion molecules. In particular, the present invention relates to a method of blocking cell adhesion molecules with monoclonal antibodies or synthesized substances.
摘要翻译： 本发明一般涉及细胞粘附分子的阻断方法。 特别地，本发明涉及用单克隆抗体或合成物质阻断细胞粘附分子的方法。
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