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公开(公告)号：US20060074033A1
公开(公告)日：2006-04-06
申请号：US10243189
申请日：2002-09-12
申请人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean-Philippe Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
发明人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean-Philippe Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
CPC分类号： C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060073579A1
公开(公告)日：2006-04-06
申请号：US10243338
申请日：2002-09-13
申请人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
发明人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
IPC分类号： C12N9/00
CPC分类号： G01N33/57484 , C07K14/47 , C07K14/705 , C12Q1/6886 , C12Q2600/136
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060073558A1
公开(公告)日：2006-04-06
申请号：US10247015
申请日：2002-09-18
申请人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
发明人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
CPC分类号： C07K14/47 , G01N33/57484
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060073557A1
公开(公告)日：2006-04-06
申请号：US10245083
申请日：2002-09-16
申请人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
发明人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
CPC分类号： C07K14/47 , C07K14/4703 , C07K14/705 , C07K16/18 , C12N2799/026
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060073550A1
公开(公告)日：2006-04-06
申请号：US10243116
申请日：2002-09-13
申请人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
发明人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060002944A1
公开(公告)日：2006-01-05
申请号：US11159919
申请日：2005-06-22
申请人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Menno Lookeren , William Wood
发明人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Menno Lookeren , William Wood
IPC分类号： A61K39/395
CPC分类号： A61K38/177 , A61K38/17 , A61K38/1709 , A61K2039/505 , C07K14/705 , C07K16/28 , C07K2317/77 , C07K2319/30 , Y02A50/463 , A61K2300/00
摘要： The present invention concerns a recently discovered macrophage specific receptor, CRIg, and its use in the treatment of complement-associated disorders.
摘要翻译： 本发明涉及最近发现的巨噬细胞特异性受体CRIg及其在补体相关疾病的治疗中的应用。
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公开(公告)号：US20070191270A1
公开(公告)日：2007-08-16
申请号：US11234694
申请日：2005-09-22
申请人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
发明人： Kevin Baker , Dan Eaton , Ellen Filvaroff , Audrey Goddard , J. Grimaldi , Austin Gurney , Victoria Smith , Jean Stephan , Colin Watanabe , William Wood , Zemin Zhang , Sherman Fong
CPC分类号： G01N33/57484 , C07K14/47 , C07K14/705 , C12Q1/6886 , C12Q2600/136
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20070190054A1
公开(公告)日：2007-08-16
申请号：US11249825
申请日：2005-10-12
申请人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Menno Lookeren , William Wood
发明人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Menno Lookeren , William Wood
IPC分类号： A61K39/395
CPC分类号： G01N33/57484 , A61K38/00 , C07K14/705 , C07K16/28 , C07K2317/24 , C07K2319/30 , G01N33/6893
摘要： The present invention concerns a recently discovered macrophage specific receptor, CRIg, and its use in the prevention and treatment of complement-associated disorders, including complement-associated eye conditions, such as age-related macular degeneration (AMD) and choroidal neovascularization (CNV).
摘要翻译： 本发明涉及最近发现的巨噬细胞特异性受体CRIg及其在预防和治疗补体相关疾病（包括补体相关性眼病）如年龄相关性黄斑变性（AMD）和脉络膜新生血管形成（CNV）中的用途。 。
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公开(公告)号：US20070031405A1
公开(公告)日：2007-02-08
申请号：US11542578
申请日：2006-10-02
申请人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , William Wood
发明人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , William Wood
IPC分类号： A61K39/395
CPC分类号： G01N33/566 , A61K2039/505 , C07K14/705 , C07K16/28 , C07K16/2803 , C07K2317/56 , C07K2319/30 , C12Q1/6883 , C12Q2600/158 , G01N33/564 , G01N33/574 , G01N33/57407 , G01N33/57492 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/102 , G01N2800/122 , G01N2800/127 , G01N2800/24
摘要： The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer.
摘要翻译： 本发明涉及治疗和诊断疾病的组合物和方法，其特征在于与炎性疾病和/或癌症相关的抗原的存在。
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公开(公告)号：US20060233803A1
公开(公告)日：2006-10-19
申请号：US11471396
申请日：2006-06-19
申请人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , Menno Lookeren , William Wood
发明人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , Menno Lookeren , William Wood
IPC分类号： A61K39/395
CPC分类号： C07K14/705 , A61K2039/505 , C07K16/28 , C07K16/2803 , C07K2317/56 , C07K2319/30 , C12Q1/6883 , C12Q2600/158 , G01N33/564 , G01N33/566 , G01N33/574 , G01N33/57407 , G01N33/57492 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/102 , G01N2800/122 , G01N2800/127 , G01N2800/24
摘要： The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer.
摘要翻译： 本发明涉及治疗和诊断疾病的组合物和方法，其特征在于与炎性疾病和/或癌症相关的抗原的存在。
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