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公开(公告)号：US20060002944A1
公开(公告)日：2006-01-05
申请号：US11159919
申请日：2005-06-22
申请人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Menno Lookeren , William Wood
发明人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Menno Lookeren , William Wood
IPC分类号： A61K39/395
CPC分类号： A61K38/177 , A61K38/17 , A61K38/1709 , A61K2039/505 , C07K14/705 , C07K16/28 , C07K2317/77 , C07K2319/30 , Y02A50/463 , A61K2300/00
摘要： The present invention concerns a recently discovered macrophage specific receptor, CRIg, and its use in the treatment of complement-associated disorders.
摘要翻译： 本发明涉及最近发现的巨噬细胞特异性受体CRIg及其在补体相关疾病的治疗中的应用。
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公开(公告)号：US20070190054A1
公开(公告)日：2007-08-16
申请号：US11249825
申请日：2005-10-12
申请人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Menno Lookeren , William Wood
发明人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Menno Lookeren , William Wood
IPC分类号： A61K39/395
CPC分类号： G01N33/57484 , A61K38/00 , C07K14/705 , C07K16/28 , C07K2317/24 , C07K2319/30 , G01N33/6893
摘要： The present invention concerns a recently discovered macrophage specific receptor, CRIg, and its use in the prevention and treatment of complement-associated disorders, including complement-associated eye conditions, such as age-related macular degeneration (AMD) and choroidal neovascularization (CNV).
摘要翻译： 本发明涉及最近发现的巨噬细胞特异性受体CRIg及其在预防和治疗补体相关疾病（包括补体相关性眼病）如年龄相关性黄斑变性（AMD）和脉络膜新生血管形成（CNV）中的用途。 。
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公开(公告)号：US20050214308A1
公开(公告)日：2005-09-29
申请号：US10964263
申请日：2004-10-12
申请人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Mary Napier , Daniel Tumas , Menno Lookeren , William Wood
发明人： Avi Ashkenazi , Karim Helmy , Sherman Fong , Audrey Goddard , Austin Gurney , Kenneth Katschke , Mary Napier , Daniel Tumas , Menno Lookeren , William Wood
IPC分类号： A61K39/395 , C07K14/705 , C07K16/28
CPC分类号： C07K14/70503 , A61K2039/505 , C07K16/2803 , C07K2317/76 , C07K2319/30 , Y10S424/809 , Y10S424/81
摘要： The present invention concerns a recently discovered macrophage specific receptor, STIgMA, and its use in the treatment of complement-associated disorders.
摘要翻译： 本发明涉及最近发现的巨噬细胞特异性受体STIgMA及其在补体相关疾病的治疗中的应用。
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公开(公告)号：US20060233803A1
公开(公告)日：2006-10-19
申请号：US11471396
申请日：2006-06-19
申请人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , Menno Lookeren , William Wood
发明人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , Menno Lookeren , William Wood
IPC分类号： A61K39/395
CPC分类号： C07K14/705 , A61K2039/505 , C07K16/28 , C07K16/2803 , C07K2317/56 , C07K2319/30 , C12Q1/6883 , C12Q2600/158 , G01N33/564 , G01N33/566 , G01N33/574 , G01N33/57407 , G01N33/57492 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/102 , G01N2800/122 , G01N2800/127 , G01N2800/24
摘要： The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer.
摘要翻译： 本发明涉及治疗和诊断疾病的组合物和方法，其特征在于与炎性疾病和/或癌症相关的抗原的存在。
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公开(公告)号：US20070190049A1
公开(公告)日：2007-08-16
申请号：US11725076
申请日：2007-03-15
申请人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , Menno Lookeren , William Wood
发明人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , Menno Lookeren , William Wood
IPC分类号： C07K16/46 , A61K39/395 , C07K14/705
CPC分类号： C07K14/705 , A61K2039/505 , C07K16/28 , C07K16/2803 , C07K2317/56 , C07K2319/30 , C12Q1/6883 , C12Q2600/158 , G01N33/564 , G01N33/566 , G01N33/574 , G01N33/57407 , G01N33/57492 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/102 , G01N2800/122 , G01N2800/127 , G01N2800/24
摘要： The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer.
摘要翻译： 本发明涉及治疗和诊断疾病的组合物和方法，其特征在于与炎性疾病和/或癌症相关的抗原的存在。
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6.发明申请公开(公告)号：US20070087007A1
公开(公告)日：2007-04-19
申请号：US11607709
申请日：2006-11-30
申请人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , William Wood
发明人： Avi Ashkenazi , Sherman Fong , Audrey Goddard , Austin Gurney , Mary Napier , Daniel Tumas , William Wood
IPC分类号： A61K39/395
CPC分类号： C07K14/47 , A61K38/00 , A61K39/395 , C07K14/705 , C07K16/28 , C07K2317/24 , C07K2319/00 , C07K2319/30 , G01N33/57484 , G01N33/6893 , G01N2800/7095 , Y02A50/54
摘要： The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer, and nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, vectors and host cells expressing such antigens PRO301, PRO362 or PRO245.
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公开(公告)号：US20060275864A9
公开(公告)日：2006-12-07
申请号：US10970823
申请日：2004-10-20
申请人： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , Christopher Grimaldi , Austin Gurney , Kenneth Hillan , Ivar Kljavin , Jennie Mather , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , P. Williams , William Wood
发明人： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , Christopher Grimaldi , Austin Gurney , Kenneth Hillan , Ivar Kljavin , Jennie Mather , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , P. Williams , William Wood
CPC分类号： C07K14/47
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060246540A1
公开(公告)日：2006-11-02
申请号：US11240891
申请日：2005-09-29
申请人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , Austin Gurney , Ivar Kljavin , Jennie Mather , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , P. Williams , William Wood , Zemin Zhang
发明人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , Austin Gurney , Ivar Kljavin , Jennie Mather , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , P. Williams , William Wood , Zemin Zhang
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20050214904A1
公开(公告)日：2005-09-29
申请号：US10970823
申请日：2004-10-20
申请人： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , Christopher Grimaldi , Austin Gurney , Kenneth Hillan , Ivar Kljavin , Jennie Mather , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , P. Williams , William Wood
发明人： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , Christopher Grimaldi , Austin Gurney , Kenneth Hillan , Ivar Kljavin , Jennie Mather , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , P. Williams , William Wood
CPC分类号： C07K14/47
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20050187382A1
公开(公告)日：2005-08-25
申请号：US10950374
申请日：2004-09-23
申请人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Ivar Kljavin , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , P. Williams , William Wood , Zemin Zhang
发明人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Ivar Kljavin , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , P. Williams , William Wood , Zemin Zhang
CPC分类号： C07K14/47
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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