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公开(公告)号：US20050152948A1
公开(公告)日：2005-07-14
申请号：US11007838
申请日：2004-12-07
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
IPC分类号： A61B5/00 , A61F2/00 , A61F2/02 , A61F2/12 , A61F2/28 , A61F13/00 , A61K9/22 , A61K38/17 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05 , A61N1/18 , A61N1/36 , A61N1/372 , A61N1/375
CPC分类号： A61N1/05 , A61K38/17 , A61L27/3641 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432 , A61L2300/45 , A61N1/36 , A61N1/372
摘要： Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.
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公开(公告)号：US20050152944A1
公开(公告)日：2005-07-14
申请号：US11006881
申请日：2004-12-07
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
IPC分类号： A61B5/00 , A61F2/00 , A61F2/02 , A61F2/12 , A61F2/28 , A61F13/00 , A61K9/22 , A61K38/17 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05 , A61N1/18 , A61N1/36 , A61N1/372 , A61N1/375
CPC分类号： A61N1/05 , A61K38/17 , A61L27/3641 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432 , A61L2300/45 , A61N1/36 , A61N1/372
摘要： Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.
摘要翻译： 软组织植入物（例如，乳房，胸部，下巴，面部，唇部和鼻部植入物）与抗瘢痕形成剂组合使用以抑制当植入物置于动物体内时可能发生的瘢痕形成。
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公开(公告)号：US20050149173A1
公开(公告)日：2005-07-07
申请号：US10986450
申请日：2004-11-10
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins , Dechi Guan
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins , Dechi Guan
IPC分类号： A61B17/00 , A61B17/11 , A61B17/12 , A61F2/00 , A61F2/86 , A61F13/00 , A61K38/48 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M29/00 , A61M31/00 , A61F2/06
CPC分类号： A61B17/12172 , A61B17/00491 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12136 , A61B17/1215 , A61B17/12177 , A61B17/12186 , A61B17/1219 , A61B2017/00004 , A61F2/86 , A61F2250/0067 , A61L31/16 , A61L2300/412
摘要： Intravascular devices (e.g., stents, stent grafts, covered stents, aneurysm coils, embolic agents and drug delivery catheters and balloons) are used in combination with fibrosing agents in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or to promote fibrosis betweent the devices and the host tissues. Compositions and methods are described for use in the treatment of aneurysms and unstable arterial (vulnerable) plaque.
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公开(公告)号：US20060240064A9
公开(公告)日：2006-10-26
申请号：US11001422
申请日：2004-12-01
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins , Dechi Guan
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins , Dechi Guan
IPC分类号： A61F2/00
CPC分类号： A61L27/54 , A61B17/11 , A61B17/12022 , A61B17/12099 , A61B17/12109 , A61B17/1214 , A61B17/12168 , A61B17/12186 , A61B17/1219 , A61B17/68 , A61F2250/0067 , A61K38/363 , A61K38/38 , A61K38/39 , A61K38/4833 , A61K45/06 , A61L31/16 , A61L2300/00 , A61L2300/412 , A61L2430/38 , A61K2300/00
摘要： Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between the implant and the host tissue.
摘要翻译： 植入物与纤维化诱导剂组合使用以诱导纤维化，否则当植入物置于动物内时可能不发生，或增加植入物和宿主组织之间的纤维化。
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公开(公告)号：US20060240063A9
公开(公告)日：2006-10-26
申请号：US11001421
申请日：2004-12-01
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
IPC分类号： A61F2/28
CPC分类号： A61L27/54 , A61B17/11 , A61B17/12022 , A61B17/12099 , A61B17/12109 , A61B17/1214 , A61B17/12168 , A61B17/12186 , A61B17/1219 , A61B17/68 , A61F2250/0067 , A61K38/363 , A61K38/38 , A61K38/39 , A61K38/4833 , A61K45/06 , A61L31/16 , A61L2300/00 , A61L2300/412 , A61L2430/38 , A61K2300/00
摘要： Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between the implant and the host tissue.
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公开(公告)号：US20050209665A1
公开(公告)日：2005-09-22
申请号：US10998351
申请日：2004-11-26
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
IPC分类号： A61B5/00 , A61F2/00 , A61F2/02 , A61F2/12 , A61F2/28 , A61F13/00 , A61K9/22 , A61K38/17 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05 , A61N1/18 , A61N1/36 , A61N1/372 , A61N1/375
CPC分类号： A61N1/05 , A61K38/17 , A61L27/3641 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432 , A61L2300/45 , A61N1/36 , A61N1/372
摘要： Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the devices are implanted within an animal.
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公开(公告)号：US20050191331A1
公开(公告)日：2005-09-01
申请号：US11001419
申请日：2004-11-30
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
IPC分类号： A61B17/11 , A61B17/12 , A61F2/00 , A61F2/02 , A61F2/04 , A61F2/06 , A61F2/28 , A61F2/44 , A61K38/00 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M16/04 , A61M31/00 , A61N1/05 , A62B9/00
CPC分类号： A61L31/16 , A61B17/11 , A61B17/12022 , A61B17/1219 , A61F2250/0067 , A61L2300/404 , A61L2300/406 , A61L2300/416 , A61L2300/426 , A61L2300/432 , A61N1/05
摘要： Implants are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal. The agent may be any suitable anti-scarring agent, e.g., a cell cycle inhibitor, and may be used in conjunction with a second pharmaceutical agent, e.g., an antibiotic. Suitable implants include intravascular implants, a vascular graft or wrap implant, an implant for hemodialysis access, an implant that provides an anastomotic connection, ventricular assist implant, a prosthetic heart valve implant, an inferior vena cava filter implant, a peritoneal dialysis catheter implant, a central nervous system shunt, an intraocular lens, an implant for glaucoma drainage, a penile implant, an endotracheal tube, a tracheostomy tube, a gastrointestinal device, and a spinal implant.
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公开(公告)号：US20050187600A1
公开(公告)日：2005-08-25
申请号：US10998350
申请日：2004-11-26
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
IPC分类号： A61B5/00 , A61F2/00 , A61F2/02 , A61F2/12 , A61F2/28 , A61F13/00 , A61K9/22 , A61K38/17 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05 , A61N1/18 , A61N1/36 , A61N1/372 , A61N1/375
CPC分类号： A61N1/05 , A61K38/17 , A61L27/3641 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432 , A61L2300/45 , A61N1/36 , A61N1/372
摘要： Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the devices are implanted within an animal.
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公开(公告)号：US20050181010A1
公开(公告)日：2005-08-18
申请号：US11001789
申请日：2004-12-01
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
IPC分类号： A61B5/00 , A61F2/00 , A61F2/02 , A61F2/12 , A61F2/28 , A61F13/00 , A61K9/22 , A61K38/17 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05 , A61N1/18 , A61N1/36 , A61N1/372 , A61N1/375
CPC分类号： A61N1/05 , A61K38/17 , A61L27/3641 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432 , A61L2300/45 , A61N1/36 , A61N1/372
摘要： Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal.
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公开(公告)号：US20050181008A1
公开(公告)日：2005-08-18
申请号：US11001786
申请日：2004-12-02
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
IPC分类号： A61B17/11 , A61B17/12 , A61F2/00 , A61F2/02 , A61F2/04 , A61F2/06 , A61F2/28 , A61F2/44 , A61K38/00 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M16/04 , A61M31/00 , A61N1/05 , A62B9/00
CPC分类号： A61L31/16 , A61B17/11 , A61B17/12022 , A61B17/1219 , A61F2250/0067 , A61L2300/404 , A61L2300/406 , A61L2300/416 , A61L2300/426 , A61L2300/432 , A61N1/05
摘要： Implants are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal. The agent may be any suitable anti-scarring agent, e.g., a cell cycle inhibitor, and may be used in conjunction with a second pharmaceutical agent, e.g., an antibiotic. Suitable implants include intravascular implants, a vascular graft or wrap implant, an implant for hemodialysis access, an implant that provides an anastomotic connection, ventricular assist implant, a prosthetic heart valve implant, an inferior vena cava filter implant, a peritoneal dialysis catheter implant, a central nervous system shunt, an intraocular lens, an implant for glaucoma drainage, a penile implant, an endotracheal tube, a tracheostomy tube, a gastrointestinal device, and a spinal implant.
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