摘要:
The present invention provides a compound of formula I or II and the use thereof in the therapeutic treatment of a central nervous system disorder related to or affected by the 5-HT6 receptor.
摘要:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated β-amyloid deposits or β-amyloid levels in a patient.
摘要:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.
摘要:
A method and apparatus for communications according to various aspects of the present invention comprises a switching system configured to receive optical signals and direct the optical signals along a selected optical path. The switching system suitably includes more than one switch, and at least one of the switches may include a variable refractive material having a first state and a second state, wherein the optical signal is transmitted via a first path when the variable refractive material is in the first state and the individual channel signal is transmitted via a second path when the variable refractive material is in the second state. The switching system may alternatively or additionally include a switch element having a reflective state and a transmissive state, wherein the optical signal is reflected via a first path when the switch element is in the reflective state and the individual channel signal is transmitted via a second path when the switch element is in the transmissive state.
摘要:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.
摘要:
An electronic package and/or package lid includes at least one connection slot for receiving a line, such as an optical fiber. The package and/or package lid also includes at least one sealant slot proximate the connection slot. Optical fibers are connected to a component, such as an opto-electronic component, through the connection slot. A sealant provided via the sealant slot hermetically seals the optical fibers within the connection slot.
摘要:
This invention provides aryloxy indole derivatives which are useful for the treatment of diseases affected by disorders of the serotonin-affected neurological systems, such as depression and anxiety, the compounds having the formula: wherein R1 is H or alkyl; R2, R3, and R4 are H, alkyl, or halogen; X is H, halogen, CN, or C1-C6 alkoxy; Z is (CH2)n or carbonyl; n is 1 or 2; and the dashed line indicates an optional double bond; or a pharmaceutically acceptable salt thereof.
摘要:
Compounds are provided which are useful for the treatment of serotonin-affected neurological disorders which comprise Wherein: R1, R2 and R3 are each, independently, hydrogen, halogen, CF3, alkyl, alkoxy, MeSO2, or together can form a 5-7 membered carbocyclic or heterocyclic ring; R4 is hydrogen, halogen, or alkyl; R5 is hydrogen, alkyl, alkylaryl, or aryl; R6 is hydrogen, halogen, CF3, CN, carbamide, or alkoxy; X1, X2 and X3 are each carbon or one of X1, X2 or X3 may be nitrogen; Y is carbon or nitrogen; and Z is carbon or nitrogen; or pharmaceutically acceptable salts thereof.
摘要翻译:提供了可用于治疗受5-羟色胺影响的神经系统疾病的化合物,其包括:R 1,R 2和R 3各自独立地为氢,卤素,CF 3,烷基,烷氧基,MeSO 2或一起可以形成5-7元碳环 或杂环; R 4为氢,卤素或烷基; R 5为氢,烷基,烷基芳基或芳基; R 6为氢,卤素,CF 3,CN,脲或烷氧基; X 1,X 2和X 3为碳或 X1,X2或X3可以是氮; Y是碳或氮; Z为碳或氮; 其药学上可接受的盐。
摘要:
Methods, apparatuses, and computer program products for synchronously debugging a software program using a plurality of virtual machines are provided. Embodiments include controlling, by a master debugging module operating on a first virtual machine, execution of the software program within the first virtual machine; controlling, by a slave debugging module operating on a second virtual machine, execution of the software program within the second virtual machine including delaying execution of the software program within the second virtual machine relative to the execution of the software program within the first virtual machine; detecting, by the master debugging module, an error in the execution of the software program within the first virtual machine; and in response to the detection of the error, capturing, by a hypervisor, a snapshot of the second virtual machine.
摘要:
A method, system and computer readable storage medium for replicating procedures with unsupported table data type arguments such as Boolean arguments. The method includes identifying the argument of an unsupported table data type in a procedure to be replicated, mapping the argument to an equivalent supported value, and creating a table containing a column representing the argument as the supported table data type and sending data corresponding to the unsupported table data type argument to a replication server.