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公开(公告)号：US20170286620A1
公开(公告)日：2017-10-05
申请号：US15621152
申请日：2017-06-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
CPC classification number: G16H40/67 , C12Q1/68 , C12Q1/6883 , C12Q1/689 , C12Q2600/118 , G06F19/30 , G06F19/3418 , G16B5/00 , G16B50/00 , G16B99/00 , G16H20/10 , G16H50/20 , G16H50/50 , Y02A90/26
Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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42.发明申请公开(公告)号：US20170277847A1
公开(公告)日：2017-09-28
申请号：US15621398
申请日：2017-06-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: G16H40/67 , G06F19/3418 , G16B35/00 , G16B40/00 , G16B50/00 , G16B50/50 , G16C20/60 , G16H20/00 , G16H50/20 , G16H50/50 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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43.发明申请公开(公告)号：US20170277845A1
公开(公告)日：2017-09-28
申请号：US15621363
申请日：2017-06-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: G06F19/3418 , C40B30/02 , G06F19/00 , G06F19/24 , G06F19/28 , G16H50/20 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号：US20170270270A1
公开(公告)日：2017-09-21
申请号：US15606909
申请日：2017-05-26
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
CPC classification number: G16H40/67 , C12Q1/68 , C12Q1/6883 , C12Q1/689 , C12Q2600/118 , G06F19/30 , G06F19/3418 , G16B5/00 , G16B50/00 , G16B99/00 , G16H20/10 , G16H50/20 , G16H50/50 , Y02A90/26
Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号：US20170268046A1
公开(公告)日：2017-09-21
申请号：US15606709
申请日：2017-05-26
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
CPC classification number: C12Q1/689 , C12Q1/6869 , C12Q1/6888 , G06F19/22
Abstract: A method and system for analyzing a microbiome of an individual, comprising: providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a lysing component and a sample preservation component and configured to receive a sample from a collection site of the individual; receiving the sample container with the sample from the collection site of the individual; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; identifying a set of microorganisms represented in the microorganism portion based upon performance of a mapping operation on portions of the microbiome sequence dataset; generating an analysis based upon a set of features related to the microorganism portion; and transmitting information derived from the analysis to the individual.
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Patent Agency Ranking
46.发明申请METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH MICROBIOME TAXONOMIC FEATURES 审中-公开用微生物衍生的诊断方法和系统和与微生物特征特征相关的条件的治疗方法公开(公告)号：US20170035346A1
公开(公告)日：2017-02-09
申请号：US15294526
申请日：2016-10-14
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman , Siavosh Rezvan Behbahani
CPC classification number: A61B5/4211 , A61B5/4233 , A61B5/4836 , A61B5/4839 , C12Q1/689 , C12Q2600/112 , G06F19/3418 , G16B40/00 , G16B50/00 , G16H20/00 , G16H40/63 , G16H50/20 , G16H50/50 , G16H50/70 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome taxonomic features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
Abstract translation: 用于表征，诊断和治疗与至少一个受试者中的微生物组分类特征有关的病症中的至少一种的方法，所述方法包括：从受试者群体接收聚集的一组生物样品; 为受试者群体生成微生物组合数据集和微生物群功能分集数据集中的至少一个; 基于从至少一个微生物组合数据集和微生物组合功能分集数据集中提取的特征产生条件的表征; 基于所述表征，产生被配置为校正所述状况的治疗模型; 并且在与受试者相关联的输出装置处，基于表征和治疗模型促进对受试者的治疗。
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47.发明申请公开(公告)号：US20160232319A1
公开(公告)日：2016-08-11
申请号：US15098153
申请日：2016-04-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman , Siavosh Rezvan Behbahani
CPC classification number: G16H50/20 , C12Q1/6874 , G06F19/3418 , G16B40/00 , G16B50/00 , G16B50/10 , G16H10/40 , G16H40/67 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating a cutaneous condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cutaneous condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cutaneous condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
Abstract translation: 一种至少一种在至少一个受试者中表征，诊断和治疗皮肤病症的方法，所述方法包括：从受试者群体接收一组聚集的生物样品; 为受试者群体生成微生物组合数据集和微生物群功能分集数据集中的至少一个; 基于从至少一个微生物组合数据集和微生物组合功能分集数据集提取的特征产生皮肤病症的表征; 基于表征，产生构造成校正皮肤病症的治疗模型; 并且在与受试者相关联的输出装置处，基于表征和治疗模型促进对受试者的治疗。
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公开(公告)号：US10380325B2
公开(公告)日：2019-08-13
申请号：US15606975
申请日：2017-05-26
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
IPC: G01N33/48 , G06F19/00 , C12Q1/68 , C12Q1/6883 , C12Q1/689 , G06F19/10 , G06F19/28 , G06F19/12 , G16H50/20 , G16H20/10 , G06G7/58
Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号：US10366793B2
公开(公告)日：2019-07-30
申请号：US15845190
申请日：2017-12-18
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Catalina Valdivia , Rodrigo Ortiz , Inti Pedroso , Victoria Dumas , Paz Tapia , Eduardo Morales
Abstract: Embodiments of a method and/or system for characterizing a microorganism-related condition (e.g., human behavior condition, disease-related condition, etc.) for a user can include one or more of: generating a microbiome dataset for each of an aggregate set of biological samples associated with a population of subjects, based on sample processing of the biological samples; processing a supplementary dataset associated with one or more microorganism-related conditions for the set of users; and performing a microorganism-related characterization (e.g., human behavior characterization, disease-related characterization, etc.) process for the one or more microorganism-related conditions, based on the supplementary dataset and/or microbiome features extracted from the microbiome dataset.
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公开(公告)号：US10366782B2
公开(公告)日：2019-07-30
申请号：US15815995
申请日：2017-11-17
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
IPC: G01N33/48 , G16H10/40 , C12Q1/6883 , G06F19/00 , G16B40/00 , G16B50/00 , G16H50/20 , H01L27/32 , H01L51/00 , H01L51/52 , G06G7/58
Abstract: A method for at least one of characterizing, diagnosing, and treating a cardiovascular disease condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cardiovascular disease condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cardiovascular disease condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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