Compression device for enhancing normal/abnormal tissue contrast in MRI including devices and methods related thereto
    42.
    发明授权
    Compression device for enhancing normal/abnormal tissue contrast in MRI including devices and methods related thereto 有权
    用于增强MRI中正常/异常组织对比度的压缩装置,包括与其相关的装置和方法

    公开(公告)号:US08380281B2

    公开(公告)日:2013-02-19

    申请号:US12772176

    申请日:2010-05-01

    IPC分类号: A61B5/05

    摘要: Featured are devices for compression of target tissue while magnetic resonance imaging the target tissue and methods and systems related thereto. The method includes disposing target tissue between the fixed surface and the moveable member of a compression device and compressing the target tissue between the fixed surface and the moveable member. The method also includes acquiring one or more, more specifically a plurality, of sequences of image data of the compressed target tissue using an MRI imaging technique (MRI). In particular embodiments, the MRI technique is a SENC MRI technique, where tissue encoding is done prior to compressing the tissue and acquiring includes adding a gradient moment in the slice-selection direction to cause demodulation with a specific frequency. In further embodiments, the sequences of image data are acquired one of during successive periodic compressions of the tissue or successive periodic relaxation of the tissues.

    摘要翻译: 特征是用于压缩目标组织的装置,而磁共振成像靶组织以及与其相关的方法和系统。 该方法包括在固定表面和压缩装置的可移动构件之间设置目标组织,并且在固定表面和可移动构件之间压缩目标组织。 该方法还包括使用MRI成像技术(MRI)获取压缩的目标组织的图像数据的一个或多个,更具体的多个序列的图像数据。 在特定实施例中,MRI技术是SENC MRI技术,其中在压缩组织之前进行组织编码,并且获取包括在切片选择方向上添加梯度时刻以引起特定频率的解调。 在另外的实施例中,在组织的连续周期性压缩或组织的连续周期性松弛期间获取图像数据的序列。

    COMPRESSION DEVICE FOR ENHANCING NORMAL/ABNORMAL TISSUE CONTRAST IN MRI INCLUDING DEVICES AND METHODS RELATED THERETO
    45.
    发明申请
    COMPRESSION DEVICE FOR ENHANCING NORMAL/ABNORMAL TISSUE CONTRAST IN MRI INCLUDING DEVICES AND METHODS RELATED THERETO 有权
    用于增强MRI中的正常/异常组织对比的压缩装置,包括装置及其相关方法

    公开(公告)号:US20110270079A1

    公开(公告)日:2011-11-03

    申请号:US12772176

    申请日:2010-05-01

    IPC分类号: A61B5/055

    摘要: Featured are devices for compression of target tissue while magnetic resonance imaging the target tissue and methods and systems related thereto. The method includes disposing target tissue between the fixed surface and the moveable member of a compression device and compressing the target tissue between the fixed surface and the moveable member. The method also includes acquiring one or more, more specifically a plurality, of sequences of image data of the compressed target tissue using an MRI imaging technique (MRI). In particular embodiments, the MRI technique is a SENC MRI technique, where tissue encoding is done prior to compressing the tissue and acquiring includes adding a gradient moment in the slice-selection direction to cause demodulation with a specific frequency. In further embodiments, the sequences of image data are acquired one of during successive periodic compressions of the tissue or successive periodic relaxation of the tissues.

    摘要翻译: 特征是用于压缩目标组织的装置,而磁共振成像靶组织以及与其相关的方法和系统。 该方法包括在固定表面和压缩装置的可移动构件之间设置目标组织,并且在固定表面和可移动构件之间压缩目标组织。 该方法还包括使用MRI成像技术(MRI)获取压缩的目标组织的图像数据的一个或多个,更具体的多个序列的图像数据。 在特定实施例中,MRI技术是SENC MRI技术,其中在压缩组织之前进行组织编码,并且获取包括在切片选择方向上添加梯度时刻以引起特定频率的解调。 在另外的实施例中,在组织的连续周期性压缩或组织的连续周期性松弛期间获取图像数据的序列。

    Non-Destructive Determination of the Pore Size Distribution and The Distribution of Fluid Flow Velocities
    46.
    发明申请
    Non-Destructive Determination of the Pore Size Distribution and The Distribution of Fluid Flow Velocities 有权
    孔径分布的非破坏性测定和流体流速的分布

    公开(公告)号:US20110095757A1

    公开(公告)日:2011-04-28

    申请号:US12675087

    申请日:2008-10-01

    IPC分类号: G01V3/175

    摘要: A method is disclosed for the non-destructive determination of the pore size distribution and the distribution of fluid flow velocities using NMR spin echo signal measurements. In one embodiment, the invention involves simultaneously injecting acoustic energy (208), generating a magnetic field having a gradient, and injecting radio-frequency electromagnetic energy (206) into a subsurface region, using for example an NMR tool and a well logging tool having an acoustic transmitter placed in a wellbore (202). The spin echo signal generated in the subsurface region is measured (210) by the NMR tool for at least two values (212) of the magnetic field gradient. A relationship is provided by which the pore fluid velocity distribution may be calculated (214) from the inverse Fourier transform of the spin echo data. The pore size distribution may then be calculated from the pore fluid velocity distribution.

    摘要翻译: 公开了一种使用NMR自旋回波信号测量法非破坏性地确定孔径分布和流体流速分布的方法。 在一个实施例中,本发明涉及同时注入声能(208),产生具有梯度的磁场,并且使用例如NMR工具和测井工具将射频电磁能(206)注入到地下区域 放置在井筒(202)中的声发射器。 通过NMR工具对磁场梯度的至少两个值(212)测量(210)在地下区域中产生的自旋回波信号。 提供了一种关系,通过该关系可以从自旋回波数据的逆傅里叶变换计算孔隙流体速度分布(214)。 然后可以从孔隙流体速度分布计算孔径分布。

    METHOD FOR ASSESSING THE PROBABILITY OF DISEASE DEVELOPMENT IN TISSUE
    47.
    发明申请
    METHOD FOR ASSESSING THE PROBABILITY OF DISEASE DEVELOPMENT IN TISSUE 审中-公开
    评估组织疾病发展概率的方法

    公开(公告)号:US20110060210A1

    公开(公告)日:2011-03-10

    申请号:US12990859

    申请日:2009-05-01

    申请人: Richard L. Ehman

    发明人: Richard L. Ehman

    IPC分类号: A61B5/055 A61B5/00

    摘要: A method for detecting conditions in tissues that can lead to disease includes an in vivo measurement of the mechanical characteristics of the tissues using Magnetic Resonance Elastography (MRE). The deviation of mechanical characteristics such as tissue stiffness from a predetermined norm is determined and indicated on an image of the tissues.

    摘要翻译: 用于检测可能导致疾病的组织中的状况的方法包括使用磁共振弹性成像(MRE)体内测量组织的机械特性。 在组织的图像上确定并指示诸如组织刚度与预定范数之间的机械特性的偏差。

    DEVICE AND PROCESS FOR MAGNETIC RESONANCE ELASTOGRAPHY (MRE)
    48.
    发明申请
    DEVICE AND PROCESS FOR MAGNETIC RESONANCE ELASTOGRAPHY (MRE) 失效
    磁共振成像仪(MRE)的设备和方法

    公开(公告)号:US20110006767A1

    公开(公告)日:2011-01-13

    申请号:US12297133

    申请日:2007-04-12

    IPC分类号: G01R33/48 G01R33/44

    摘要: The invention relates to a device to produce mechanical oscillations in a research object using magnetic resonance elastography (MRE) with a membrane that can be set into periodic motion (312) and a transmission element (4, 400) for the transmission of periodic motion of the membrane (312) onto the research object (1), whereby the membrane (312) is connected to the transmission element (4, 400) by means of a mounting medium (311, 320, 321, 322) in such a way that periodic motion of the membrane is transmitted over the mounting medium (311, 320, 321, 322) to the transmission element (4, 400). A second aspect relates to the invention of a device with a step motor to generate periodic motion and a transmission element for the transmission of the periodic motion of the step motor to the research object in order to generate mechanical oscillation therein. The invention also relates to a procedure for the magnetic resonant elastographic determination of biomechanical characteristics of tissue with steps: c) excitation of mechanical oscillations using a frequency of fv in which n is the tissue to be researched; d) proof of mechanical oscillation within the tissue using magnetic resonance, whereby a periodic magnetic field with a repeat time of TR≦1/fv is used on the tissue.

    摘要翻译: 本发明涉及一种使用磁共振弹性成像(MRE)在研究对象中产生机械振荡的装置,该装置具有能够被设置为周期性运动的膜(312)和用于传输周期性运动的传输元件(4,400) 膜(312)到研究对象(1)上,由此膜(312)借助于安装介质(311,320,321,322)连接到传动元件(4,400),使得 膜的周期运动通过安装介质(311,320,321,322)传递到传动元件(4,400)。 第二方面涉及具有用于产生周期性运动的步进电动机的装置的发明和用于将步进电动机的周期性运动传递到研究对象以便在其中产生机械振荡的传动元件。 本发明还涉及以下步骤用于磁共振弹性成像确定组织生物力学特征的步骤:c)使用其中n是要研究的组织的频率fv激发机械振荡; d)使用磁共振证明组织内的机械振荡,由此在组织上使用重复时间为TR≦̸ 1 / fv的周期磁场。