摘要:
A method and apparatus (100) for vibrating an organ and/or tissue and/or region of a subject's body (202) without a mechanical transmission to characterize at least one mechanical property of the region and/or tissue and/or organ, the apparatus (100) includes: elements (114-118) for generating a pressure wave of a given frequency in a gaseous medium, and waveguide elements (106) for guiding, in a gaseous medium, the pressure wave from the generating elements (114-118) to a human or animal body (202). Wave guiding in the airways of a human or animal body and tissue displacement mapping, anisotropy, and mechanical property characterizing systems (300) and methods are also described.
摘要:
Featured are devices for compression of target tissue while magnetic resonance imaging the target tissue and methods and systems related thereto. The method includes disposing target tissue between the fixed surface and the moveable member of a compression device and compressing the target tissue between the fixed surface and the moveable member. The method also includes acquiring one or more, more specifically a plurality, of sequences of image data of the compressed target tissue using an MRI imaging technique (MRI). In particular embodiments, the MRI technique is a SENC MRI technique, where tissue encoding is done prior to compressing the tissue and acquiring includes adding a gradient moment in the slice-selection direction to cause demodulation with a specific frequency. In further embodiments, the sequences of image data are acquired one of during successive periodic compressions of the tissue or successive periodic relaxation of the tissues.
摘要:
A dynamic magnetic resonance elastography (“MRE”) method for quantifying liver stiffness using intrinsic transient waveforms imparted on the liver by the beating heart is provided. The method includes synchronizing motion-encoding gradients in an MRE pulse sequence to the subject's cardiac cycle.
摘要:
Featured are devices for compression of target tissue while magnetic resonance imaging the target tissue and methods and systems related thereto. The method includes disposing target tissue between the fixed surface and the moveable member of a compression device and compressing the target tissue between the fixed surface and the moveable member. The method also includes acquiring one or more, more specifically a plurality, of sequences of image data of the compressed target tissue using an MRI imaging technique (MRI). In particular embodiments, the MRI technique is a SENC MRI technique, where tissue encoding is done prior to compressing the tissue and acquiring includes adding a gradient moment in the slice-selection direction to cause demodulation with a specific frequency. In further embodiments, the sequences of image data are acquired one of during successive periodic compressions of the tissue or successive periodic relaxation of the tissues.
摘要:
A method is disclosed for the non-destructive determination of the pore size distribution and the distribution of fluid flow velocities using NMR spin echo signal measurements. In one embodiment, the invention involves simultaneously injecting acoustic energy (208), generating a magnetic field having a gradient, and injecting radio-frequency electromagnetic energy (206) into a subsurface region, using for example an NMR tool and a well logging tool having an acoustic transmitter placed in a wellbore (202). The spin echo signal generated in the subsurface region is measured (210) by the NMR tool for at least two values (212) of the magnetic field gradient. A relationship is provided by which the pore fluid velocity distribution may be calculated (214) from the inverse Fourier transform of the spin echo data. The pore size distribution may then be calculated from the pore fluid velocity distribution.
摘要:
A method for detecting conditions in tissues that can lead to disease includes an in vivo measurement of the mechanical characteristics of the tissues using Magnetic Resonance Elastography (MRE). The deviation of mechanical characteristics such as tissue stiffness from a predetermined norm is determined and indicated on an image of the tissues.
摘要:
The invention relates to a device to produce mechanical oscillations in a research object using magnetic resonance elastography (MRE) with a membrane that can be set into periodic motion (312) and a transmission element (4, 400) for the transmission of periodic motion of the membrane (312) onto the research object (1), whereby the membrane (312) is connected to the transmission element (4, 400) by means of a mounting medium (311, 320, 321, 322) in such a way that periodic motion of the membrane is transmitted over the mounting medium (311, 320, 321, 322) to the transmission element (4, 400). A second aspect relates to the invention of a device with a step motor to generate periodic motion and a transmission element for the transmission of the periodic motion of the step motor to the research object in order to generate mechanical oscillation therein. The invention also relates to a procedure for the magnetic resonant elastographic determination of biomechanical characteristics of tissue with steps: c) excitation of mechanical oscillations using a frequency of fv in which n is the tissue to be researched; d) proof of mechanical oscillation within the tissue using magnetic resonance, whereby a periodic magnetic field with a repeat time of TR≦1/fv is used on the tissue.
摘要:
An array of two or more piezoelectric drivers generates shear waves in a region of interest of a human undergoing a MRE test. The use of the array of drivers allows for better diagnosis of disease of the humans or animals.
摘要:
A microwave imaging system provides superior breast imaging resolution by combining MR microwave absorption and MR-compatible microwave tomography calculations. These techniques may also be supplemented with magnetic resonance elastography techniques, for example, to facilitate quick multispectral imaging.