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    Non-invasive microwave analysis methods
    4.
    发明授权
    Non-invasive microwave analysis methods 失效
    无创微波分析方法

    公开(公告)号：US07755010B2

    公开(公告)日：2010-07-13

    申请号：US11589625

    申请日：2006-10-30

    申请人： Edward M Godshalk ,  Timothy Raynolds ,  Paul M. Meaney ,  Keith D. Paulsen ,  Greg Burke

    发明人： Edward M Godshalk ,  Timothy Raynolds ,  Paul M. Meaney ,  Keith D. Paulsen ,  Greg Burke

    IPC分类号： H05B6/64 ,  A61B5/05

    CPC分类号： G01N22/00 ,  A61B5/05 ,  A61B5/0507 ,  A61B2562/02 ,  A61B2562/046

    摘要： A non-invasive microwave analysis method determines scattered phase and/or amplitude data for a liquid in a container. A transmitter antenna transmits microwaves that scatter from the container and the liquid in the container. One or more receiver antennas convert the microwaves into microwave electronic signals that are processed to determine the scattered phase and/or amplitude data. Another non-invasive microwave screening method includes placing a container of an unknown liquid in a tank. The container is separated by a membrane from coupling liquid in the tank. Microwave radiation transmits from a transmitter antenna and scatters from the container and the unknown liquid. One or more receiver antennas convert the microwave radiation into microwave electronic signals. The microwave electronic signals are processed to determine scattered phase and/or amplitude data. A pass result or a fail result is determined based on the scattered phase and/or amplitude data.

    摘要翻译： 非侵入性微波分析方法确定容器中的液体的散射相位和/或振幅数据。 发射机天线发射从容器散射的微波和容器中的液体。 一个或多个接收器天线将微波转换成微波电子信号，其被处理以确定散射相位和/或振幅数据。 另一种非侵入性微波筛选方法包括将未知液体的容器放置在罐中。 容器通过膜与罐中的耦合液分离。 微波辐射从发射天线发射并从容器和未知液体散射。 一个或多个接收机天线将微波辐射转换为微波电子信号。 处理微波电子信号以确定散射相位和/或振幅数据。 基于散射相位和/或振幅数据确定通过结果或失败结果。

    Fixed array microwave imaging apparatus and method
    5.
    发明授权
    Fixed array microwave imaging apparatus and method 有权
    固定阵列微波成像装置及方法

    公开(公告)号：US06448788B1

    公开(公告)日：2002-09-10

    申请号：US09580309

    申请日：2000-05-26

    申请人： Paul M. Meaney ,  Keith D. Paulsen ,  Margaret W. Fanning

    发明人： Paul M. Meaney ,  Keith D. Paulsen ,  Margaret W. Fanning

    IPC分类号： G01R2732

    CPC分类号： A61B5/0507 ,  A61B5/0536 ,  H01Q21/20 ,  H01Q21/28

    摘要： An improved method and apparatus for microwave imaging of an inhomogeneous target, in particular of biological tissue, compensates for the interactions between active antennae and nonactive antennae. Measured electric field data are processed in magnitude and phase form so that unwrapped phase information may be used directly in the image reconstruction. Initial finite element measurements and calculations are used to determine the perimeter dimensions of the target being examined, resulting in more accurate image reconstructions. An improved regularization technique is a hybrid of a Marquardt regularization scheme with a spatial filtering technique and a Tikhonov regularization scheme. An improved switching matrix enables simultaneous sampling of electric field data from a plurality of receiving antennae.

    摘要翻译： 用于微波成像不均匀靶（特别是生物组织）的改进方法和装置补偿了有源天线与非主动天线之间的相互作用。 测量的电场数据以幅度和相位形式被处理，使得可以在图像重建中直接使用解包相位信息。 初始有限元测量和计算用于确定正在检查的目标的周长尺寸，导致更准确的图像重建。 改进的正则化技术是Marquardt正则化方案与空间滤波技术和Tikhonov正则化方案的混合。 改进的开关矩阵能够从多个接收天线同时采样电场数据。

    Two-dimensional microwave imaging apparatus and methods
    7.
    发明授权
    Two-dimensional microwave imaging apparatus and methods 失效
    二维微波成像设备及方法

    公开(公告)号：US5841288A

    公开(公告)日：1998-11-24

    申请号：US798885

    申请日：1997-02-11

    申请人： Paul M. Meaney ,  Keith D. Paulsen

    发明人： Paul M. Meaney ,  Keith D. Paulsen

    IPC分类号： G01N22/00 ,  G01R29/08

    CPC分类号： G01N22/00

    摘要： The invention provides apparatus and methods for determining electric field properties of an inhomogeneous target. The electric property distribution on a coarse mesh discretization of the target is first estimated; and then the electric field on a fine mesh discretization of the target is computed. The fine mesh has finer discretization than the coarse mesh and is overlapping with the coarse mesh. The electric field is then measured at preselected measurement sites within a homogeneous region external to the target. A Jacobian matrix is also calculated which represents a sensitivity calculation relative to a change in the electric field at selected measurement sites due to a perturbation in the electric property distribution on the coarse mesh. A difference vector is formed between the computed electric field and the measured electric field, and an update vector is added to the electrical property distribution as a function of the difference vector and the Jacobian matrix. The electric field is then re-computed based on the updated electric property distribution, which is compared with the measured electric field to produce a least squared error. If this error is not sufficiently small, the steps above, beginning with computing a Jacobian matrix, are repeated until the error is sufficiently small.

    摘要翻译： 本发明提供了用于确定不均匀目标的电场特性的装置和方法。 首先估算目标粗网格离散化的电性质分布; 然后计算目标精细网格离散化的电场。 细网具有比粗网更细的离散性，并与粗网重叠。 然后在目标外部的均匀区域内的预选的测量位置处测量电场。 还计算出雅可比矩阵，其表示相对于在粗网格上的电特性分布中的扰动在选定测量位置处的电场变化的灵敏度计算。 在所计算的电场和测量的电场之间形成差矢量，并且将更新矢量作为差矢量和雅可比矩阵的函数加到电特性分布上。 然后基于更新的电特性分布重新计算电场，其与测量的电场进行比较以产生最小平方误差。 如果该误差不够小，则重复上述步骤，从计算雅可比矩阵开始，直到误差足够小。

    System and method for collection and use of magnetic resonance data and microwave data to identify boundaries of interest
    8.
    发明授权
    System and method for collection and use of magnetic resonance data and microwave data to identify boundaries of interest 有权
    用于收集和使用磁共振数据和微波数据以识别感兴趣边界的系统和方法

    公开(公告)号：US08977340B2

    公开(公告)日：2015-03-10

    申请号：US13577788

    申请日：2011-02-09

    申请人： Amir H. Golnabi ,  Keith D. Paulsen ,  Paul M. Meaney

    发明人： Amir H. Golnabi ,  Keith D. Paulsen ,  Paul M. Meaney

    IPC分类号： A61B5/055 ,  A61B5/00 ,  A61B6/03 ,  G06T7/00 ,  A61B5/05

    CPC分类号： A61B5/0035 ,  A61B5/0059 ,  A61B5/0507 ,  A61B5/055 ,  A61B5/4312 ,  A61B6/032 ,  G06T7/0012 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/30068

    摘要： A system and method for detecting permittivity and conductivity boundaries within a high resolution spatial image of a material is presented. Electrical properties of a material, such as permittivity and conductivity, may assist in identification of physical properties of the material. Structural boundaries within tissue may be identified in spatial images, such as MR images. Image reconstruction algorithms may combine these structural boundaries with microwave images of the tissue to determine the permittivity and conductivity parameters within the structural boundaries. In the case of soft tissue, the microwave images may be captured simultaneously with the spatial images. The microwave images may be taken at a different time from the spatial image for rigid tissue. The method may be employed for two dimensional or three dimensional image reconstruction.

    摘要翻译： 提出了一种用于在材料的高分辨率空间图像内检测介电常数和电导率边界的系统和方法。 材料的电学性质，例如介电常数和电导率可有助于识别材料的物理性质。 可以在诸如MR图像的空间图像中识别组织内的结构边界。 图像重建算法可以将这些结构边界与组织的微波图像结合，以确定结构边界内的介电常数和电导率参数。 在软组织的情况下，微波图像可以与空间图像同时捕获。 可以在与刚性组织的空间图像不同的时间拍摄微波图像。 该方法可以用于二维或三维图像重建。

    Planar Probe And System For Measuring Dielectric Properties Of Biological Materials
    9.
    发明申请
    Planar Probe And System For Measuring Dielectric Properties Of Biological Materials 有权
    用于测量生物材料介电性能的平面探头和系统

    公开(公告)号：US20140375337A1

    公开(公告)日：2014-12-25

    申请号：US14117368

    申请日：2012-05-11

    申请人： Paul M. Meaney ,  Tina Zhou ,  Andrea Borsic ,  Alexander T. Farkas ,  Keith D. Paulsen

    发明人： Paul M. Meaney ,  Tina Zhou ,  Andrea Borsic ,  Alexander T. Farkas ,  Keith D. Paulsen

    IPC分类号： G01N27/02 ,  G01N33/483 ,  G01N33/49

    CPC分类号： G01N27/02 ,  G01N27/221 ,  G01N33/4833 ,  G01N33/49 ,  G01N2333/435

    摘要： A probe sensor has a printed circuit comprising a coplanar transmission line, a ground plane, a plated-through contact via, and a part-circular ring of ground vias surrounding the contact via. The coplanar transmission line and ground plane are formed on a first layer of the printed circuit, and the contact via and part-circular ring of ground vias are plated with a conductive biocompatible material on a second layer of the printed circuit. A system uses a network analyzer with the probe to measure electrical properties of biological tissue. Also described is a method of using the system to determine qualities of stored blood.

    摘要翻译： 探头传感器具有印刷电路，该印刷电路包括共面传输线，接地平面，电镀通孔接触通孔和围绕接触通孔的接地通孔的部分圆形环。 共面传输线和接地平面形成在印刷电路的第一层上，并且接地通路的接触通孔和部分圆形环在印刷电路的第二层上镀有导电生物相容性材料。 系统使用带有探针的网络分析仪来测量生物组织的电学性质。 还描述了使用该系统来确定储存血液的质量的方法。

    SYSTEM AND METHOD FOR COLLECTION & USE OF MAGNETIC RESONANCE DATA & MICROWAVE DATA TO IDENTIFY BOUNDARIES OF INTEREST
    10.
    发明申请
    SYSTEM AND METHOD FOR COLLECTION & USE OF MAGNETIC RESONANCE DATA & MICROWAVE DATA TO IDENTIFY BOUNDARIES OF INTEREST 有权
    用于收集和使用磁共振数据和微波数据识别边界的系统和方法

    公开(公告)号：US20130204118A1

    公开(公告)日：2013-08-08

    申请号：US13577788

    申请日：2011-02-09

    申请人： Amir H. Golnabi ,  Keith D. Paulsen ,  Paul M. Meaney

    发明人： Amir H. Golnabi ,  Keith D. Paulsen ,  Paul M. Meaney

    IPC分类号： A61B5/00 ,  A61B6/03 ,  A61B5/055

    CPC分类号： A61B5/0035 ,  A61B5/0059 ,  A61B5/0507 ,  A61B5/055 ,  A61B5/4312 ,  A61B6/032 ,  G06T7/0012 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/30068

    摘要： A system and method for detecting permittivity and conductivity boundaries within a high resolution spatial image of a material is presented. Electrical properties of a material, such as permittivity and conductivity, may assist in identification of physical properties of the material. Structural boundaries within tissue may be identified in spatial images, such as MR images. Image reconstruction algorithms may combine these structural boundaries with microwave images of the tissue to determine the permittivity and conductivity parameters within the structural boundaries. In the case of soft tissue, the microwave images may be captured simultaneously with the spatial images. The microwave images may be taken at a different time from the spatial image for rigid tissue. The method may be employed for two dimensional or three dimensional image reconstruction.

    摘要翻译： 提出了一种用于在材料的高分辨率空间图像内检测介电常数和电导率边界的系统和方法。 材料的电学性质，例如介电常数和电导率可有助于识别材料的物理性质。 可以在诸如MR图像的空间图像中识别组织内的结构边界。 图像重建算法可以将这些结构边界与组织的微波图像结合，以确定结构边界内的介电常数和电导率参数。 在软组织的情况下，微波图像可以与空间图像同时捕获。 可以在与刚性组织的空间图像不同的时间拍摄微波图像。 该方法可以用于二维或三维图像重建。