公开(公告)号：US20010039436A1

公开(公告)日：2001-11-08

申请号：US09903970

申请日：2001-07-11

发明人： Andrew G.C. Frazier ,  Michael D. Lesh ,  Chad C. Roue ,  Erik J. van der Burg

IPC分类号： A61D001/00

CPC分类号： A61B17/0057 ,  A61B17/00234 ,  A61B17/0401 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/12122 ,  A61B2017/00243 ,  A61B2017/00292 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00632 ,  A61B2017/00668 ,  A61B2017/0409 ,  A61B2017/0412 ,  A61B2017/0414 ,  A61B2017/0417 ,  A61B2017/042 ,  A61B2017/0437 ,  A61B2017/0445 ,  A61B2017/0454 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0477 ,  A61B2017/048 ,  A61B2017/0488 ,  A61B2017/0645 ,  A61B2017/0647 ,  A61F2/24 ,  A61F2/2427 ,  A61F2/2487 ,  Y10S606/907

摘要： Disclosed is an anastomosis catheter, for achieving a tissue to tissue or synthetic graft to tissue attachment. The catheter includes a plurality of deployable tissue anchors, which may be laterally deployed into surrounding tissue. The anchors may be used to achieve end to end or end to side anastomoses. Methods are also disclosed.

摘要翻译： 公开了一种用于实现组织到组织或合成移植物到组织附着的吻合导管。 导管包括多个可展开的组织锚，其可以横向地布置到周围组织中。 锚可以用于实现端对端或端到端吻合。 还公开了方法。

公开(公告)号：US20040267311A1

公开(公告)日：2004-12-30

申请号：US10490517

申请日：2004-03-23

发明人： Frank J. Viola ,  David Ivanko

IPC分类号： A61B017/04 ,  A61B017/10 ,  A61D001/00 ,  A61B017/08

CPC分类号： A61B17/07207 ,  A61B17/0686 ,  A61B2017/00526 ,  A61B2017/0725 ,  A61B2017/07271 ,  A61B2017/2933 ,  A61B2090/0814

摘要： The present disclosure is directed to staple-gap adjustment members for use in surgical stapling apparatus and methods. A gap adjustment member includes one or more bearing portions sharing a common rotational axis and one or more cam surface portions having a periphery with at least two different points along the periphery, with each point along the periphery having a different radius from the rotational axis. The one or more cam surface portions can have a central axis parallel to and spaced a distance from the rotational axis of the one or more bearing portions.

摘要翻译： 本公开涉及用于外科缝合装置和方法的缝合钉间隙调节构件。 间隙调整构件包括一个或多个共用共同旋转轴线的轴承部分和一个或多个凸轮表面部分，该凸轮表面部分具有沿周边具有至少两个不同点的周边，沿着周边的每个点具有与旋转轴线不同的半径。 一个或多个凸轮表面部分可以具有平行于并且与一个或多个轴承部分的旋转轴线间隔一定距离的中心轴线。

公开(公告)号：US20040267310A1

公开(公告)日：2004-12-30

申请号：US09972594

申请日：2001-10-05

发明人： David C. Racenet ,  Hanspeter R. Bayer ,  Scott Cunningham

IPC分类号： A61D001/00 ,  A61B017/08 ,  A61B017/04 ,  A61B017/10

CPC分类号： A61B17/0682 ,  A61B17/0644 ,  A61B17/068 ,  A61B17/0684 ,  A61B17/0686 ,  A61B17/072 ,  A61B17/07207 ,  A61B17/115 ,  A61B2017/07264 ,  A61B2017/320052

摘要： In accordance with the present disclosure a directionally biased staple is provided for use in all types of surgical staplers having anvil structure against which the staple is formed. The directionally biased staple may be constructed in a wide variety of cross-sectional configurations including rectangular, elliptical, trapezoidal, etc. All of the configurations are distinguished by having a bending region requiring more force to twist or malform the staple than is required to properly form the staple. Preferably, these staples have Moment of Inertia Ratios on the order of between about 1.1 to about 3.0. The staple preferably corresponds in other respects to conventional formed staples, i.e. having at least a pair of leg members interconnected by a crown portion wherein the leg members are formed by direct contact with the anvil. An anvil assembly is also provided for minimizing the malformation of staples.

公开(公告)号：US20040267309A1

公开(公告)日：2004-12-30

申请号：US10607650

申请日：2003-06-27

发明人： Dennis D. Garvin

IPC分类号： A61D001/00 ,  A61B017/08

CPC分类号： A61B17/08 ,  A61B17/0643 ,  A61B2017/00004 ,  A61B2017/0641 ,  A61B2017/081

摘要： The invention discloses a device and technique for a sutureless wound closure, which limits the risks of rupture and scarring. The device comprises a two-part strap having short hooks or barbs on the ventral surface. The barbs are curved and flexible such that, when urged in one direction, the barbs do not engage while when urged in the opposite direction, the barbs are pushed downward and engage the tissue of the wound. By deploying one strap on each side of the wound, fastening the two straps in the middle of the wound and tightening the ends, the wound is closed. The tension required to close the wound is distributed along the length of the straps, thus resulting in a cleaner, safer closure.

摘要翻译： 本发明公开了一种用于无缝线伤口闭合的装置和技术，其限制了破裂和瘢痕形成的风险。 该装置包括在腹侧表面上具有短钩或倒钩的两部分带。 倒钩是弯曲的和柔性的，使得当沿一个方向被推动时，倒钩在相反方向被推动时不啮合，倒钩被向下推动并接合伤口的组织。 通过在伤口的每一侧部署一个皮带，将两个皮带紧固在伤口的中间并拧紧末端，伤口关闭。 关闭伤口所需的张力沿带的长度分布，从而导致更清洁，更安全的闭合。

公开(公告)号：US20040267307A1

公开(公告)日：2004-12-30

申请号：US10806927

申请日：2004-03-22

申请人： Access Closure, Inc.

发明人： Celso J. Bagaoisan ,  Juan Domingo ,  Nicanor Domingo ,  Farhad Khosravi ,  Suresh S. Pai

IPC分类号： A61D001/00 ,  A61B017/08 ,  A61B017/00

CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B2017/00557 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61M25/10182 ,  A61M25/10187 ,  A61M2025/0681

摘要： Apparatus for sealing a puncture includes an elongate occlusion member having a balloon attached to distal ends of telescoping inner and outer members. A housing on the proximal end of the outer member includes a piston coupled to the inner member and slidable within a chamber communicating with a fluid reservoir. A switch on the housing is actuated to direct fluid from the reservoir through the outer member into the balloon to expand the balloon and into the chamber to move the piston and pull the inner member, shortening the balloon as it expands. During use, the distal end of the occlusion member is introduced into a puncture communicating with a vessel until the collapsed balloon is disposed within the vessel. The balloon is expanded, and a tensioner is connected to the housing to apply a proximal force holding the balloon against the vessel wall to seal the puncture.

摘要翻译： 用于密封穿刺的装置包括具有附接到伸缩的内部和外部构件的远端的气囊的细长闭塞构件。 外部构件的近端上的壳体包括联接到内部构件并可在与流体储存器连通的腔室内滑动的活塞。 启动壳体上的开关以将流体从储存器引导通过外部构件进入气囊，以使气囊膨胀并进入腔室中，以移动活塞并拉动内部构件，从而在气囊膨胀时缩短气囊。 在使用期间，将阻塞构件的远端引入到与血管连通的穿刺件中，直到将收缩的气囊设置在血管内。 气囊膨胀，并且张紧器连接到壳体以施加将气囊保持抵靠血管壁的近侧力以密封穿刺。

公开(公告)号：US20040215231A1

公开(公告)日：2004-10-28

申请号：US10182044

申请日：2002-11-01

发明人： David Fortune ,  Jose Velada ,  Patrick Trotter ,  David Mandley ,  Peter Edwardson

IPC分类号： A61D001/00

CPC分类号： A61B17/686 ,  A61B17/0057 ,  A61B17/064 ,  A61B17/11 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00659 ,  A61B2017/0647 ,  A61F2/0063 ,  A61F2/30767 ,  A61F2/92 ,  A61F2/94 ,  A61F2002/0072 ,  A61L17/08 ,  A61L31/005

摘要： There are described devices implantable in the human or animal body. Such a device takes the form of a pre-formed three-dimensional article, comprising at least in part a material which is hydratable and capable of bonding to tissue whilst retaining its integrity. The material may be activated, leading to cross-linking of the material and the formation of chemical bonds between the material and tissue to which it is applied. In preferred embodiments the material has self-adhesive properties. The article may have a wide variety of shapes to suit its intended purpose, and may be manufactured by a variety of methods.

摘要翻译： 描述了可植入人体或动物体内的装置。 这种装置采用预先形成的三维制品的形式，其至少部分包括可水合并且能够粘合到组织同时保持其完整性的材料。 材料可以被激活，导致材料的交联和在其所施加的材料和组织之间形成化学键。 在优选的实施方案中，该材料具有自粘性。 该制品可以具有各种形状以适合其预期目的，并且可以通过各种方法制造。

公开(公告)号：US20040153122A1

公开(公告)日：2004-08-05

申请号：US10356214

申请日：2003-01-30

申请人： INTEGRATED VASCULAR SYSTEMS, INC.

发明人： Thomas Palermo

IPC分类号： A61D001/00 ,  A61B017/08

CPC分类号： A61B17/064 ,  A61B17/0057 ,  A61B17/0643 ,  A61B17/0644 ,  A61B17/068 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/00637 ,  A61B2017/00672

摘要： An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.

公开(公告)号：US20040133236A1

公开(公告)日：2004-07-08

申请号：US10662000

申请日：2003-09-12

申请人： NMT Medical, Inc.

发明人： Andrzej J. Chanduszko

IPC分类号： A61D001/00

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606

摘要： The present invention provides devices for closing septal defects, such as a patent foramen ovale (PFO). The closure devices include a proximal anchor member, a distal anchor member, and at least one flexible center joint connecting the two anchor members. According to some embodiments, the proximal and/or distal anchor members may include a generally cylindrical member split along the central portion of its length to form an elongate oval. The proximal and/or distal anchor members may further include a tissue scaffold. At least some of the closure devices according to the present invention are repositionable and retrievable.

摘要翻译： 本发明提供了用于闭合中隔缺损的装置，例如卵圆孔（PFO）。 闭合装置包括近端锚固构件，远侧锚固构件和连接两个锚定构件的至少一个柔性中心接头。 根据一些实施例，近端锚固构件和/或远端锚固构件可以包括沿其长度的中心部分分开的大致圆柱形构件，以形成细长的椭圆形。 近端和/或远端锚定构件还可包括组织支架。 根据本发明的至少一些闭合装置是可重新定位和可回收的。

公开(公告)号：US20040111115A1

公开(公告)日：2004-06-10

申请号：US10664099

申请日：2003-09-17

发明人： Jennifer Maw

IPC分类号： A61D001/00

CPC分类号： A61D1/00 ,  A61B17/00491 ,  A61B2017/2923 ,  A61B2017/2925

摘要： Disclosed are applicators for applying medical adhesives or other media, particularly application of adhesives to small or delicate areas such as in the ear. Preferred applicators comprise a handle to hold the applicator and a trigger to actuate a dispensing mechanism which serves to express media or adhesive from a reservoir out through a cannula where is applied to the desired tissue or surface.

摘要翻译： 公开了用于施用医用粘合剂或其它介质的涂布器，特别是在诸如耳朵中的小或微小区域上施加粘合剂。 优选的施用器包括用于保持施用器的手柄和用于致动分配机构的触发器，该分配机构用于将储存器中的介质或粘合剂通过插管施加到所需的组织或表面。

公开(公告)号：US20030229376A1

公开(公告)日：2003-12-11

申请号：US10389696

申请日：2003-03-14

申请人： BioInteractions Ltd.

发明人： Shivpal S. Sandhu

IPC分类号： A61D001/00

CPC分类号： A61B17/00491 ,  A61B17/0057 ,  Y10T428/2996 ,  Y10T428/31928

摘要： A wound closure apparatus is provided which utilizes blood fluid by activating the clotting cascade of blood fluid outside the body within a substantially enclosed sterile container then introducing, the blood fluid to the wound site to complete clotting. An apparatus for providing ways of inhibiting anticoagulating agents, and slowing fibrin clot degradation are also disclosed. Kits for practicing the invention singularly or in combination with, and/or associated with preferred procedures are also disclosed. The invention provides a clotting cascade initiation apparatus (1) including a substantially enclosed sterile containment chamber within which an aliquot of blood fluid, either autologous or from donor sources can be received, and retained. In preferred embodiments, the sterile containment chamber further includes a heparin binding agent which will bind heparin and remove it from the blood fluid. In further embodiments, the containment chamber will also include a procoagulating agent, wherein a clotting cascade can be initiated when the blood fluid is accepted into the sterile containment chamber.

摘要翻译： 提供了一种创伤闭合装置，其利用血液流体，通过在基本上封闭的无菌容器内激活身体外部的血液流体的凝血级联，然后将血液流体引入伤口部位以完成凝血。 还公开了一种用于提供抑制抗凝剂的方法以及减缓纤维蛋白凝块降解的装置。 还公开了单独实施本发明或与优选方法组合和/或与其相关联的试剂盒。 本发明提供了一种凝血级联引发装置（1），其包括基本上封闭的无菌容纳室，其中可以接收自体或来自供体来源的血液的等分试样并保留。 在优选的实施方案中，无菌容纳室还包括肝素结合剂，其将结合肝素并将其从血液中除去。 在另外的实施方案中，容纳室还将包括促凝剂，其中当血液流体被接受到无菌容纳室中时可以开始凝血级联。