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    Clip applier and methods of use
    2.
    发明申请
    Clip applier and methods of use 有权
    夹子施放器和使用方法

    公开(公告)号：US20040153123A1

    公开(公告)日：2004-08-05

    申请号：US10638115

    申请日：2003-08-08

    申请人： Integrated Vascular Systems, Inc.

    发明人： Thomas J. Palermo ,  William M. Belef ,  Michael T. Carley ,  Richard S. Ginn ,  Ronald J. Jabba ,  Anthony Pantages

    IPC分类号： A61D001/00

    CPC分类号： A61B17/064 ,  A61B17/0057 ,  A61B17/0643 ,  A61B17/0644 ,  A61B17/068 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/00637 ,  A61B2017/00672

    摘要： An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.

    摘要翻译： 一种用于将闭合元件输送到形成在血管或其他体腔中的开口中的装置及其制造和使用方法。 该装置构造成保持封闭元件，使得封闭元件基本上设置在该装置内。 该装置还可以将封闭件基本上邻近开口附近的血管壁接合并定位。 在封闭元件的展开过程中，该装置将闭合元件膨胀超过封闭元件的自然横截面，使得封闭元件在展开时构造成与大量的血管壁和/或组织接合。 接合血管壁和/或组织，闭合元件进一步构造成返回到自然横截面，从而将所接合的血管壁和/或组织基本上闭合和/或密封，使得开口内止血 增强。

    Apparatus and method for sealing a body vessel puncture
    4.
    发明申请
    Apparatus and method for sealing a body vessel puncture 审中-公开
    用于密封体血管穿刺的装置和方法

    公开(公告)号：US20030050664A1

    公开(公告)日：2003-03-13

    申请号：US10234109

    申请日：2002-09-05

    发明人： Jan O. Solem

    IPC分类号： A61D001/00 ,  A61B017/08

    CPC分类号： A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00654

    摘要： An apparatus for sealing a puncture in a body vessel has a sealing member (10) comprising a flexible tubing (11) having an internal passageway (14). The tubing (11) is provided at an open distal end (15) thereof with an elastic expansion member (16) for self-expanding said open distal end (15) to an expanded configuration; and a pursing member (20) which is arranged to purse said flexible tubing (11). A method for sealing a puncture in a body vessel, comprises introducing a distal end of the sealing member through the puncture; allowing the elastic expansion member to self-expand to an expanded configuration in the vessel, detecting a blood flow through the internal passageway as an indication of the distal end of the sealing member being positioned inside the body vessel, and thereafter sealing the internal passageway by pursing the flexible tubing outside the body vessel.

    摘要翻译： 用于在身体容器中密封穿刺的装置具有包括具有内部通道（14）的柔性管（11）的密封构件（10）。 管道（11）在其开放的远端（15）处设置有弹性膨胀构件（16），用于将所述开口远端（15）自膨胀至膨胀构型; 以及设置成用于包装所述柔性管道（11）的追索构件（20）。 一种用于在身体容器中密封穿刺的方法，包括：通过所述穿刺引入所述密封构件的远端; 允许弹性膨胀构件在容器内自膨胀至膨胀构型，检测通过内部通道的血液流动，作为密封构件的远端位于体体内的指示，然后将内部通道密封 在身体船体外追求柔性管。

    Controlled viscosity dermal adhesive
    5.
    发明申请
    Controlled viscosity dermal adhesive 审中-公开
    受控粘度皮肤粘合剂

    公开(公告)号：US20030050613A1

    公开(公告)日：2003-03-13

    申请号：US10145581

    申请日：2002-05-13

    发明人： Julius G. Hammerslag

    IPC分类号： A61D001/00 ,  A61B017/08 ,  A61M035/00

    CPC分类号： A61B17/085 ,  A61B17/00491 ,  A61B17/0057 ,  A61B2017/0065 ,  A61L24/0089 ,  C08L35/04

    摘要： Disclosed are methods and compositions for closing and sealing a wound, laceration, incision, or other percutaneous opening using an adhesive. In one preferred embodiment, the sides of the percutaneous opening are brought together in apposition and the adhesive is applied to the opening and the skin immediately adjacent thereto. Adhesives used in the methods of the present invention exhibit sufficient viscosity to substantially prevent flow of the adhesive into the percutaneous opening. In a preferred embodiment, the adhesive is a sealing medium comprising an adhesive component and a microparticulate component. Preferred sealing media comprise cyanoacrylates combined with filmed silica. In such embodiments, said viscosity enhancing component is present in an amount sufficient to substantially prevent the medium from flowing into the opening at normal skin temperature.

    摘要翻译： 公开了用于使用粘合剂封闭和密封伤口，裂伤，切口或其它经皮开口的方法和组合物。 在一个优选实施例中，经皮开口的侧面被并置在一起，并且将粘合剂施加到开口和紧邻其的皮肤。 在本发明的方法中使用的粘合剂表现出足够的粘度以基本上防止粘合剂流入经皮开口。 在优选实施方案中，粘合剂是包含粘合剂组分和微粒组分的密封介质。 优选的密封介质包括与成膜二氧化硅组合的氰基丙烯酸酯。 在这样的实施方案中，所述增粘组分的存在量足以基本上防止介质在正常皮肤温度下流入开口。

    Wound closure system and methods
    6.
    发明申请
    Wound closure system and methods 失效
    伤口闭合系统及方法

    公开(公告)号：US20030018357A1

    公开(公告)日：2003-01-23

    申请号：US10143495

    申请日：2002-05-09

    发明人： Ajay K. Luthra ,  Shivpal S. Sandhu ,  Simon Jon Onis

    IPC分类号： A61D001/00

    CPC分类号： A61B17/0057 ,  A61B2017/0065 ,  A61L24/0005

    摘要： A wound closure system and methods utilizes a patient's own blood. The system preferably includes a chamber with a needle and a plunger for transferring and storing blood prior to surgery and the use of reversible anticoagulants. The chamber is pre-loaded with a reversible anticoagulant to prevent the blood from clotting during storage. When the surgery is complete, a counteracting agent is mixed with the withdrawn blood to counteract the reversible anticoagulant and allow the blood to clot. The clottable blood is then reintroduced into the patient to close a wound.

    摘要翻译： 伤口闭合系统和方法利用患者自己的血液。 该系统优选地包括具有针的室和用于在手术之前转运和储存血液并使用可逆抗凝剂的柱塞。 该腔室预装有可逆抗凝血剂，以防止血液在储存过程中凝结。 当手术完成时，将抗反应剂与取出的血液混合以抵抗可逆抗凝剂并允许血液凝结。 然后将可凝结血液重新引入患者以闭合伤口。

    Apparatus and methods for providing tactile feedback while delivering a closure device
    9.
    发明申请
    Apparatus and methods for providing tactile feedback while delivering a closure device 有权
    提供闭合装置时提供触觉反馈的装置和方法

    公开(公告)号：US20020072768A1

    公开(公告)日：2002-06-13

    申请号：US10006400

    申请日：2001-11-30

    发明人： Richard S. Ginn

    IPC分类号： A61B017/08 ,  A61D001/00

    CPC分类号： A61B17/0057 ,  A61B17/064 ,  A61B34/76 ,  A61B2017/00367 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00663 ,  A61B2017/00668 ,  A61B2017/00672 ,  A61B2017/081

    摘要： An apparatus for sealing a passage through tissue includes a tubular member, a plug, and a locator member. The plug is disposed on a distal end of the tubular member and includes an external thread. The locator member is inserted into a lumen of the tubular member until a distal portion is disposed beyond the plug. The distal portion includes a helically wound wire and a tether coupled to the wire that is movable for causing the wire to buckle. To seal a passage communicating with a blood vessel, the distal portion of the locator member is inserted into the passage, and the plug is threaded into the passage until the distal portion extends into the vessel. The tether is pulled to buckle the wire, and the plug is unthreaded until the buckled wire contacts a wall of the vessel, whereupon the plug is released to seal the passage.

    摘要翻译： 用于密封通过组织的通道的装置包括管状构件，塞子和定位构件。 塞子设置在管状构件的远端并且包括外螺纹。 定位器构件插入到管状构件的内腔中，直到远端部分设置在塞子之外。 远侧部分包括螺旋缠绕的线和联接到线的系绳，其可移动以使线扣合。 为了密封与血管连通的通道，定位器构件的远端部分插入通道中，并且将塞子拧入通道中，直到远端部分延伸到血管内。 系绳被拉动以扣紧线，并且插头是无螺纹的，直到带扣的线接触到容器的壁，然后释放插头以密封通道。