Cardio myopeptidin, the production and the use thereof
    45.
    发明申请
    Cardio myopeptidin, the production and the use thereof 有权
    心脏肌肽,其生产和使用

    公开(公告)号:US20070117745A1

    公开(公告)日:2007-05-24

    申请号:US10567286

    申请日:2004-02-23

    申请人: Yusong Chen Shu Li

    发明人: Yusong Chen Shu Li

    CPC分类号: C07K14/4716 A61K38/00

    摘要: The present invention relates to a cardio myopeptidin which is isolated from the hearts of non-human healthy mammals. The molecular weight of the cardio myopeptidin is less than 10000 Dalton, the peptide content thereof being 75%˜90%, the free amino acid content 6%˜15%, the ribonucleic acid content less than 2%, and the deoxyribonucleic acid content less than 7.5%. The present invention further provides a method of producing the cardio myopeptidin and the use thereof in producing pharmaceuticals for treating cardiac disorders, specifically the use in producing pharmaceuticals for treating myocardial ischemic and reperfusion injury. The cardio myopeptidin of the present invention can work directly on myocytes, promoting the repair of injuries caused by various reasons, and providing a new way to relieve ischemic and reperfusion injury, and to promote the repair of injured myocardium.

    摘要翻译: 本发明涉及从非人健康哺乳动物的心脏中分离的心脏肌肽。 心肌肌肽的分子量小于10000道尔顿,肽含量为75%〜90%,游离氨基酸含量为6%〜15%,核糖核酸含量低于2%,脱氧核糖核酸含量较少 超过7.5%。 本发明还提供了生产心肌肌肽的方法及其在制备用于治疗心脏病的药物中的用途,特别是用于制备治疗心肌缺血和再灌注损伤的药物的用途。 本发明的心脏肌肽可以直接在肌细胞上起作用,促进由各种原因造成的损伤的修复,并提供减轻缺血和再灌注损伤的新方法,并促进损伤心肌的修复。

    REDUCTION OF SALTINESS WITH SWEETENERS
    46.
    发明申请
    REDUCTION OF SALTINESS WITH SWEETENERS 审中-公开
    减少与贪婪的肮脏

    公开(公告)号:US20070082061A1

    公开(公告)日:2007-04-12

    申请号:US11465741

    申请日:2006-08-18

    摘要: The present invention provides compositions for bowel cleansing that have improved palatability through the inclusion of a sweetener, such as a chlorinated sucrose isomer. The invention also provides methods of reducing the saltiness of an orally consumed substance, including phosphate salt and PEG/salt bowel cleansers, through the use of a sweetener. Utilizing a sweetener including Sucralose to reduce the saltiness of a substance unexpectedly contradicts the conventional belief that sweeteners amplify saltiness.

    摘要翻译: 本发明提供了通过包含甜味剂如氯化蔗糖异构体而具有改善的适口性的肠清洗组合物。 本发明还提供了通过使用甜味剂降低口服食物(包括磷酸盐和PEG /盐肠清洁剂)的咸味的方法。 使用包括三氯蔗糖在内的甜味剂来减少物质的咸味,这意味着与甜味剂增加咸味的传统观点相矛盾。

    Drugs for the arthritis treatment
    47.
    发明申请
    Drugs for the arthritis treatment 审中-公开
    药物用于关节炎治疗

    公开(公告)号:US20070010458A1

    公开(公告)日:2007-01-11

    申请号:US10509675

    申请日:2003-03-27

    申请人: Piero Del Soldato

    发明人: Piero Del Soldato

    摘要: Antiinflammatory and/or antiinflammatory/analgesic compounds having the following general formula: A-(B)b0—(C)c0—N(O)s  (I) or salts thereof, wherein: A contains the radical of a non steroidal antiinflammatory or non steroidal antiinflammatory/analgesic drug, B and C are bivalent linking groups, are used in the arthritis therapy.

    摘要翻译: 具有以下通式的抗炎和/或抗炎/镇痛化合物:<?in-line-formula description =“In-line formula”end =“lead”?> A-(B)b0 < (C)C 0 -N(O)n(I)<?in-line-formula description =“In-line Formulas”end =“tail”?>或 其盐,其中:A包含非甾体抗炎或非甾体抗炎/止痛药物的基团,B和C是二价连接基团,用于关节炎治疗。

    Diluent for immunohistochemistry
    48.
    发明申请
    Diluent for immunohistochemistry 审中-公开
    稀释剂用于免疫组织化学

    公开(公告)号:US20070003564A1

    公开(公告)日:2007-01-04

    申请号:US11473941

    申请日:2006-06-23

    摘要: An embodiment of the invention is directed to a method and diluent for stabilizing biomolecules, comprising Tris and a polyhydroxy carbohydrate selected from the group consisting of mannitol and trehalose. The diluent may optionally include casein added as a background blocking protein. The diluent may optionally include sodium azide as an anti-microbial agent. Mannitol and/or trehalose are particularly useful embodiments of polyhydroxy carbohydrates.

    摘要翻译: 本发明的一个实施方案涉及用于稳定生物分子的方法和稀释剂,其包含Tris和选自甘露醇和海藻糖的多羟基碳水化合物。 稀释剂可以任选地包括作为背景阻断蛋白加入的酪蛋白。 稀释剂可以任选地包括叠氮化钠作为抗微生物剂。 甘露醇和/或海藻糖是多羟基碳水化合物的特别有用的实施方案。