公开(公告)号：US11866409B2

公开(公告)日：2024-01-09

申请号：US15772699

申请日：2016-11-02

申请人： CARMEL-HAIFA UNIVERSITY ECONOMIC CORPORATION LTD.

发明人： Sarit Larisch ,  Dalit Barkan

IPC分类号： C07D209/42 ,  C07D231/14 ,  C07D217/02 ,  A61K31/496 ,  A61K45/06 ,  A61P35/00

CPC分类号： C07D209/42 ,  A61K31/496 ,  A61K45/06 ,  A61P35/00 ,  C07D217/02 ,  C07D231/14

摘要： Provided are ARTS mimetic compounds that act as novel antagonists for XIAP and Bcl-2. Further, the novel ARTS mimetic compounds of the presently claimed subject matter induce apoptosis and/or differentiation in premalignant and malignant cells and thereby restore their normal-like phenotype. Further provided are compositions, methods and uses of said ARTS mimetic compounds in the treatment of cancer and premalignant conditions.

公开(公告)号：US11856841B2

公开(公告)日：2023-12-26

申请号：US18169524

申请日：2023-02-15

申请人： DUK SAN NEOLUX CO., LTD. ,  SAMSUNG DISPLAY CO., LTD.

发明人： Ki Won Kim ,  Kyung Hwan Oh ,  Bu Yong Yun ,  Hyung Dong Lee ,  Jin Woo Shin ,  Soung Yun Mun ,  Jae Duk Yoo ,  Jung Geun Lee ,  Joon Gu Lee ,  Yeon Hwa Lee ,  Mi Kyung Kim ,  Ji Hyun Seo ,  Kwan Hee Lee

IPC分类号： C07C22/08 ,  H01L51/00 ,  H01L51/50 ,  H10K85/60 ,  H10K85/40 ,  C07D213/26 ,  C07D253/02 ,  C07C211/56 ,  C07D333/76 ,  C07D307/92 ,  C07C43/29 ,  C07C323/09 ,  C07F7/08 ,  C07D209/86 ,  C07D307/91 ,  C07D311/96 ,  C07D487/04 ,  C07D307/93 ,  H10K50/82

CPC分类号： H10K85/615 ,  C07C22/08 ,  C07C43/29 ,  C07C211/56 ,  C07C323/09 ,  C07D209/86 ,  C07D213/26 ,  C07D253/02 ,  C07D307/91 ,  C07D307/92 ,  C07D307/93 ,  C07D311/96 ,  C07D333/76 ,  C07D487/04 ,  C07F7/081 ,  C07F7/0816 ,  H10K85/40 ,  H10K85/60 ,  H10K85/622 ,  C07C2601/16 ,  C07C2602/10 ,  C07C2603/24 ,  C07C2603/42 ,  H10K50/82

摘要： Provided are a fluorinated compound for patterning a metal or an electrode (cathode), an organic electronic element using the same, and an electronic device thereof, wherein a fine pattern of the electrode is formed by using the fluorinated compound as a material for patterning a metal or an electrode (cathode), without using a shadow mask, and it is possible to more easily apply UDC since it is easy to manufacture a transparent display having high light transmittance.

公开(公告)号：US11850669B2

公开(公告)日：2023-12-26

申请号：US17862652

申请日：2022-07-12

申请人： KYOCERA SGS PRECISION TOOLS, INC.

发明人： Ian Edward Holliday ,  Emil Dobosz ,  Barry Leslie Ward ,  Antony James Theaker ,  David Cawkwell

IPC分类号： B23C3/28 ,  B23C5/10

CPC分类号： B23C3/28 ,  B23C5/10 ,  B23C2210/084 ,  B23C2220/366

摘要： A slot milling sequence includes a plurality of material removal processes or operations. Each of the material removal operations includes utilization of an end mill tool. Some of the material removal operations utilize trochoidal tool paths, whereas other material removal processes utilize one or more profile cuts. Some material removal operations that utilize profile cuts remove material from both sides of the cut in a single pass, whereas other material removal operations remove material from one side of the cut via a first pass of the end mill tool and remove material from the opposing side of the cut via a second pass of the end mill tool.

公开(公告)号：US11850169B2

公开(公告)日：2023-12-26

申请号：US17053133

申请日：2018-05-08

申请人： TT TOOTH TRANSFORMER S.R.L.

发明人： Elio Minetti

IPC分类号： A61F2/46

CPC分类号： A61F2/4644 ,  A61F2002/4645 ,  A61F2002/4646

摘要： An apparatus for transforming teeth into bone material, which is suitable to treat the teeth by immersion in liquids and includes a reactor device including a contactor, a reaction chamber, an ejection chamber, a cartridge including a plurality of containers for the processing and washing liquids, separated liquid-tight from each other, a fragmentation device suitable to fragment teeth, a guide suitable to detachably connect the cartridge and the fragmentation device to the apparatus, and a movement device suitable to detachably connect at least partially the reactor device and allow it to sequentially withdraw the teeth from the fragmentation device and the liquids from the cartridge.

公开(公告)号：US11844834B2

公开(公告)日：2023-12-19

申请号：US16966726

申请日：2019-01-30

申请人： SL VAXIGEN, INC.

发明人： Yong Bok Seo ,  Youngwoo Choi ,  Sang Hee Sim

IPC分类号： A61K39/29 ,  A61K39/39 ,  A61P35/00 ,  A61K39/00

CPC分类号： A61K39/39 ,  A61K39/292 ,  A61P35/00 ,  A61K2039/55538

摘要： There is provided a novel vaccine adjuvant, and more specifically, a vaccine adjuvant for stimulating a T lymphocyte-specific immune response, which includes an IL-12 protein and an IL-21 protein as active ingredients, or includes the polynucleotide encoding an IL-12 protein and the polynucleotide encoding an IL-21 protein as active ingredients.

公开(公告)号：US11840269B2

公开(公告)日：2023-12-12

申请号：US17058458

申请日：2019-06-20

申请人： KETER PLASTIC LTD. ,  MILWAUKEE ELECTRIC TOOL CORPORATION

发明人： Yaron Brunner ,  Izhar Shany ,  Uri Parizer

IPC分类号： B62B1/12 ,  B62B1/00 ,  B62B1/14 ,  B62B3/02 ,  B62B3/04

CPC分类号： B62B1/12 ,  B62B1/002 ,  B62B1/14 ,  B62B3/02 ,  B62B3/04 ,  B62B2202/12

摘要： Provided is a hand truck comprising a frame having a first end, and a second end configured with a wheel set, and a ledge extending at said second end, wherein one or both of the frame and the ledge is configured with an articulation arrangement for detachably attaching thereto a utility unit, the articulation arrangement extending parallel to a plane of the respective frame or ledge.

公开(公告)号：US11827844B2

公开(公告)日：2023-11-28

申请号：US18059167

申请日：2022-11-28

申请人： Integrity Bio-Chemicals, LLC

发明人： Christopher P. Gardner ,  Stephen William Almond

IPC分类号： C11D1/88 ,  C11D1/66 ,  C11D3/20 ,  C11D3/26 ,  C09K8/60 ,  C11D1/825 ,  C11D1/835 ,  C11D1/94 ,  C11D3/22 ,  C11D1/46 ,  C11D1/90 ,  C11D1/72

CPC分类号： C09K8/604 ,  C11D1/66 ,  C11D1/825 ,  C11D1/835 ,  C11D1/94 ,  C11D3/2079 ,  C11D3/22 ,  C11D3/221 ,  C11D3/222 ,  C09K2208/28 ,  C11D1/46 ,  C11D1/662 ,  C11D1/72 ,  C11D1/90

摘要： Compositions comprising a neutral surfactant or a reaction product thereof and a reaction product of a saccharide polymer and a fatty acid may be obtained in the presence of water and a hydroxide base (optionally in the presence of the neutral surfactant), the saccharide polymer comprising a dextran, a dextrin compound, or any combination thereof. The reaction product of the saccharide polymer and the fatty acid may be present at a concentration effective to lower surface tension of the neutral surfactant. Depending on the fatty acid identity, among other factors, the compositions may promote emulsification or de-emulsification. In addition, the compositions may promote foam formation under appropriate conditions. Treatment fluids comprising the compositions, including foamed treatment fluids, may be introduced into a subterranean formation to perform a treatment operation in which fluid emulsification or de-emulsification may occur. The reaction products may be incorporated in soaps and other personal care products.

公开(公告)号：US11826233B2

公开(公告)日：2023-11-28

申请号：US15733338

申请日：2019-01-02

申请人： Guy Soffer

发明人： Guy Soffer

IPC分类号： A61F11/00 ,  A61M31/00 ,  A61F11/20

CPC分类号： A61F11/202 ,  A61M31/00 ,  A61M2205/0216 ,  A61M2205/0288 ,  A61M2205/0294 ,  A61M2205/584 ,  A61M2205/587 ,  A61M2210/0675 ,  A61M2210/1425

摘要： Provided is a medical device with portions configured for fitting and being retained simultaneously into two cavities on opposite sides of the body of a subject, for example the eustachian tubes or the fallopian tubes. The device may include an elongated member with a central segment and first and second peripheral segments extending therefrom. These segments differ in their intended function and eventual in situ positioning: the two peripheral segments intended for insertion and positioning within the two cavities and exerting their function within the cavities. The central segment serves as a link between two peripheral segments and may also be used for some other functions by its position. The elongated member may have elastic properties.

公开(公告)号：US11826117B2

公开(公告)日：2023-11-28

申请号：US16995150

申请日：2020-08-17

申请人： Auris Health, Inc.

发明人： Daniel T. Wallace ,  Travis Michael Schuh ,  Spencer James Witte

IPC分类号： A61B34/00 ,  A61B17/29 ,  A61B34/30

CPC分类号： A61B34/71 ,  A61B17/29 ,  A61B2017/2936 ,  A61B2017/2947 ,  A61B2034/301 ,  A61B2034/302 ,  A61B2034/303

摘要： A robotic system can include a high force instrument that amplifies input forces such that output forces are greater than input forces. The high force instrument can include an end effector. The high force instrument can further include a first pulley configured to rotate about a pulley axis and a first jaw member connected to the first pulley by a first drive pin. The high force instrument can also include a second pulley configured to rotate about the pulley axis and a second jaw member connected to the second pulley by a second drive pink. A link can provide a first pivot point about which the first jaw member can pivot and a second pivot point about which the second jaw member can pivot.

公开(公告)号：USD1004879S1

公开(公告)日：2023-11-14

申请号：US29789869

申请日：2021-10-21

申请人： Keter Home and Garden Products Ltd.

设计人： Ehud Ben-Avi

摘要： FIG. 1 is a top, front and left-side isometric view of a trash bin, showing my new design, in a closed position;
FIG. 2 is a front view of the bin of FIG. 1;
FIG. 3 is a back view of the trash bin of FIG. 1;
FIG. 4 is a left-side view of the trash bin of FIG. 1; right-side view being a mirror image;
FIG. 5 is a top view of the trash bin of FIG. 1;
FIG. 6 is a bottom view of the trash bin of FIG. 1;
FIG. 7 is a bottom, back, left-side isometric view of the trash bin of FIG. 1; and,
FIG. 8 is a top, front and left-side isometric view of the bin of FIG. 1 in an opened position.