公开(公告)号：US11013564B2

公开(公告)日：2021-05-25

申请号：US16241263

申请日：2019-01-07

Applicant: Board of Regents of the University of Nebraska

Inventor： Joseph Palmowski ,  Shane Farritor

IPC: B25J17/02 ,  A61B34/30 ,  B25J9/12 ,  B25J9/10

Abstract: Disclosed herein are various robotic surgical devices and systems that include first and second elongate bodies, first and second driveshafts disposed through the second elongate body, and an in-line shoulder joint with a robotic arm coupled thereto. In certain implementations, the in-line shoulder joint has a differential yoke and a dual shaft disposed within the yoke lumen.

公开(公告)号：US20210130206A1

公开(公告)日：2021-05-06

申请号：US17089472

申请日：2020-11-04

Applicant: The Board of Regents of the University of Nebraska

Inventor： Paul N. Black ,  James W. Allen ,  Timothy J. Nicodemus

IPC: C02F3/32

Abstract: A method and system for reducing the concentration of nitrogen-bound nitrate from at least one of groundwater, surface water, or waste water is disclosed. The system includes an algal photobioreactor system. The photobioreactor includes a transparent tubular structure, a medium disposed inside the transparent tubular structure, and alga configured to adhere to the medium. The photobioreactor further includes a pump, and a light source. The method includes providing contaminant-containing water, adding the water to the algal photobioreactor system, adjusting at least one of temperature, ion concentration, CO2 concentration, pH, light wavelength, ion concentration or light intensity in the algal photobioreactor system to enhance growth of algae, removing water from the algal photobioreactor system, and harvesting the algal biomass. A system and method are also disclosed for reducing the concentration of organophosphates from water via an organophosphate-removing alga.

公开(公告)号：US20210079312A1

公开(公告)日：2021-03-18

申请号：US16772110

申请日：2018-12-14

Applicant: UNIVERSITY OF NORTH TEXAS ,  BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA ,  INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION ,  HUAZHONG AGRICULUTRUAL UNIVERSITY

Inventor： Diana BERMAN ,  Kent Dean CHAPMAN ,  Tervor Bradley ROMSDAHL ,  Edgar Benjamin CAHOON ,  Robert Earl MINTO ,  Chunyu ZHANG

IPC: C10M169/00 ,  C10M109/02 ,  C10M105/40 ,  C10M117/04 ,  C10M119/20

Abstract: Various liquid and semisolid lubricant compositions are provided, in particular lubricant compositions containing oil from the seeds of the Brassicaceae Orychophragmus violaceus, preferably those that have been esterified with one or more fatty acids such as palmitoleic acid, oleic acid, linoleic acid, lauric acid, palmitic acid, stearic acid, or a combination thereof. In various aspects, lubricant compositions are provided that include a petroleum or a synthetic base oil and about 40% or less by weight of a liquid lubricant composition containing oil from the seeds of the Brassicaceae Orychophragmus violaceus, preferably those that have been esterified with one or more fatty acids. In various aspects, semisolid lubricant composition are provided containing an emulsion of (i) a thickener and (ii) an oil from the seeds of the Brassicaceae Orychophragmus violaceus, preferably those that have been esterified with one or more fatty acids.

公开(公告)号：US10881303B2

公开(公告)日：2021-01-05

申请号：US16087988

申请日：2017-03-22

Applicant: Board of Regents of the University of Nebraska

Inventor： Irving H. Zucker ,  Alicia Marie Schiller ,  Peter Ricci Pellegrino

IPC: A61B5/02 ,  A61B5/021 ,  A61B5/20 ,  A61B5/00 ,  A61B5/024

Abstract: Sympathetic vasomotor identification and quantification systems that provide ways to assess therapies, diseases, and conditions which affect sympathetic innervation and function are described. Because sympathetic vasomotion relies on intact, functional sympathetic nerves, some embodiments of the sympathetic vasomotor identification and quantification systems described herein include a signal processing functionality that establishes sympathetic vasomotor signatures through the collection of arterial blood pressure and blood flow signals.

公开(公告)号：US20200277711A1

公开(公告)日：2020-09-03

申请号：US16647690

申请日：2018-09-19

Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA

Inventor： Jingwei Xie

IPC: D01D5/00 ,  D01F8/14 ,  D04H3/011 ,  D06M23/10

Abstract: Expanded, nanofiber structures are provided as well as methods of use thereof and methods of making.

公开(公告)号：US20200263147A1

公开(公告)日：2020-08-20

申请号：US16868246

申请日：2020-05-06

Applicant: Northwestern University ,  Board of Regents of the University of Nebraska ,  Trustees of Tufts College (AKA Tufts University)

Inventor： Gregory A. Smith ,  Patricia Jane Sollars ,  Gary Edward Pickard ,  Ekaterina E. Heldwein

IPC: C12N7/00 ,  A61K35/763 ,  C07K14/005 ,  A61K39/25 ,  A61K39/245 ,  A61K39/12

Abstract: Provided herein are compositions and methods for vaccination and research applications. In particular, provided herein are non-neuroinvasive herpesviruses and alpha herpesviruses and uses thereof.

公开(公告)号：US20200255815A1

公开(公告)日：2020-08-13

申请号：US16854551

申请日：2020-04-21

Applicant: Board of Regents of the University of Nebraska

Inventor： Benjamin J. Pavlik ,  Paul Blum ,  Kevin Van Cott

IPC: C12N9/52 ,  C12N15/62 ,  C07K14/33 ,  A61K49/00 ,  A61K38/45 ,  A61K47/64

Abstract: An engineered payload-delivery system includes a target cell binding unit, covalently bound to a pore forming unit, and a payload portion adapted with a region capable of non-covalently binding to the pore forming unit. The pore forming unit is derived from a particular sub-serotype of Clostridium toxin, while the payload region is derived from a different sub-serotype of Clostridium toxin. The disclosed chimeric protein-based composition is capable of specifically delivering payload to neural cells.

公开(公告)号：US20200078567A1

公开(公告)日：2020-03-12

申请号：US16681301

申请日：2019-11-12

Applicant: Board of Regents of the University of Nebraska

Inventor： Gregory Gordon

IPC: A61M25/06 ,  A61M1/36 ,  A61M39/08 ,  A61M25/02 ,  A61M25/01 ,  A61B17/34 ,  A61M25/00

Abstract: The present application includes a sheath that is suitable for use in a variety of medical procedures. In one or more implementations, the sheath includes a shunt member, and a curvable portion. The curvable portion may be configured in various orientations to facilitate an intervention, such as a hemodialysis intervention, or the like, by an operator. The curvable portion may be configured to bend between a substantially straight configuration and a curved configuration. In implementations, the sheath may be configured to have detachable and/or interchangeable components (e.g., shunt member, curvable portion, etc.).

公开(公告)号：US20190261866A1

公开(公告)日：2019-08-29

申请号：US16087988

申请日：2017-03-22

Applicant: Board of Regents of the University of Nebraska

Inventor： Irving H. Zucker ,  Alicia Marie Schiller ,  Peter Ricci Pellegrino

IPC: A61B5/02 ,  A61B5/00 ,  A61B5/021 ,  A61B5/20

Abstract: Sympathetic vasomotor identification and quantification systems that provide ways to assess therapies, diseases, and conditions which affect sympathetic innervation and function are described. Because sympathetic vasomotion relies on intact, functional sympathetic nerves, some embodiments of the sympathetic vasomotor identification and quantification systems described herein include a signal processing functionality that establishes sympathetic vasomotor signatures through the collection of arterial blood pressure and blood flow signals.

公开(公告)号：US10344340B2

公开(公告)日：2019-07-09

申请号：US15274097

申请日：2016-09-23

Applicant: Board of Regents of the University of Nebraska

Inventor： Sally Ann Mackenzie ,  Roberto De la Rosa Santamaria

IPC: A01H1/04 ,  C12N15/82 ,  C12Q1/6895 ,  C12N15/113

Abstract: The present invention provides methods for obtaining plants that exhibit useful traits by transient suppression of the MSH1 gene of the plants. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants.