摘要:
A connector for producing a fluid connection to a second connector, wherein the connector can, in at least one connector area, form a weakened structure, in order to be able to break open the connector in the connector area and in this way produce a fluid connection to the second connector. A partial area of the connector area is designed in such a way that the weakened structure in the partial area can be generated by covering or spraying the connector area with a medium.
摘要:
The invention relates to an aqueous pharmaceutical composition, preferably an infusion solution, for parenteral administration which contains paracetamol and has an electrical conductivity of not more than 200 μS cm−1. The invention relates to an aqueous pharmaceutical composition, preferably an infusion solution, for parenteral administration which contains paracetamol and has an electrical conductivity of not more than 200 μS cm−1.v
摘要:
In an arrangement of a rack (1) and a medical device (2) to be attached to the rack (1), the rack (1) comprises a first connection element (111) and the medical device (2) comprises a second connection element (211) which in an attached state of the rack (1) and the medical device (2) is releasably connected to the first connection element (111) of the rack (1) to establish an electrical connection between the medical device (2) and the rack (1). The first connection element (111) and the second connection element (211) each comprise at least two electrical contacts (111.1, 211.1), wherein in the attached state of the rack (1) and the medical device (2) via the at least two electrical contacts (111.1, 211.1) both a low speed data connection (15, 25) and a high speed data connection (14, 24) between the medical device (2) and the rack (1) is established. Thus, an arrangement of a rack and a medical device is provided which allows for an easy attachment of the medical device to the rack by providing a secure and reliable and at the same time versatile electrical connection between the medical device and the rack.
摘要:
The invention concerns a tube pump comprising a cradle (1) with a cavity (11) suitable for the accommodation of a tube clamp (2). It further concerns a tube clamp (2) for a flexible tube, the tube clamp being suitable for accommodation in a tube pump, the tube clamp having a mobile part and an immobile part (20) designed to penetrate at least partly into a housing (11) realized in the tube pump. The invention also concerns a perfusion set. Finally, the invention concerns a system comprising a tube pump and a tube clamp. In order to provide a system comprising a tube pump and a tube clamp with improved operation safety, the tube pump has a cavity (11) with at least one protrusion (14) and the tube clamp (2) has means (21) for snapping attachment of the tube clamp behind the protrusion (14). This arrangement allows to fix the tube clamp (2) safely in the cavity (11) and to give furthermore a feedback to the user because he feels (and he might in addition hear) that the tube clamp has snapped behind the protrusion. A further advantage resides in the fact that the solution according to the present invention can be put in place without significantly increasing the costs of the parts involved in the invention.
摘要:
For cooling organs and tissues in transplantation medicine, only ice preparations are used so far which are not soft like a gel and are brought to the necessary degree of comminution by mechanically comminuting frozen, sterile, pyrogen-free isotonic infusion solutions, such as 5% glucose or 0.9% saline, with great effort. The lack of gel-like consistency of the preparations and the expensive production process are very disadvantageous.Therefore, it was necessary to produce a cooling preparation for transplantation medicine, which in a temperature range from −5° C. to 4° C. is gel-like and soft, transparent and sufficiently mechanically stable and yet remains formable. In accordance with the invention, such preparation can be produced from gelatin solutions in the concentration range of 3-20 wt-%, which are isotonized or adjusted to 280-650 mosmol/kg and are almost pH-neutral, by simple cooling and/or freezing.
摘要:
The invention relates to a method for the preparation of a hydroxyalkyl starch derivative which comprises reacting hydroxyalkyl starch (HAS) via the optionally oxidised reducing end of the HAS with the amino group M of a crosslinking compound which, apart from the amino group, comprises a specifically protected carbonyl group, namely an acetal group or a ketal group.
摘要:
An adapter is connected to a probe tube of a PEG probe that is already in place, the probe tube being cut off above the abdominal wall of the patient. The adapter comprises an outer retaining element, which is supported on the abdominal wall, and comprises structure for fastening the proximal end of the PEG probe, and structure for connecting a delivery line to the flow channel. A shut-off element having a rotatable or displaceable closing body is provided for closing the PEG probe. The adapter is characterized by its universal use, simple handleability and small overall height.
摘要:
The present invention relates to novel liquid pharmaceutical compositions of adalimumab, which include adalimumab or a biosimilar thereof, an histidine buffering agent such as histidine (or histidine buffer system such as histidine/imidazolium-histidine), and a sugar stabiliser such as trehalose. Such a combination of components furnishes formulations having a stability (e.g. on storage and when exposed to stress) which is comparable to or an improvement upon those known in the art, and with fewer ingredients. Such advances will help adalimumab treatments to become more widely available at lower cost, and prolong the viability of pre-loaded delivery devices (e.g. pre-filled syringes) to reduce unnecessary waste of the drug.
摘要:
The invention relates to a process for manufacturing oil-in-water emulsions with a PFATs value that remains below 0.05% for at least 24 hours, preferably for at least 48 hours after admixing the emulsions with an amino acid and a glucose solution suitable for parenteral administration.