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公开(公告)号：US20240065940A1
公开(公告)日：2024-02-29
申请号：US17894455
申请日：2022-08-24
CPC分类号： A61J1/2096 , A61J1/1418 , A61J1/1468 , A61J1/18 , A61J1/2027 , A61J1/2048
摘要： An assembly includes an injection device including a container for a product. The container includes a distal tip encompassing a channel providing a passageway for transferring the product, and an adaptor mounted onto the distal tip. The assembly further includes a heat-shrinkable film covering at least part of the container and at least part of the adaptor. The heat-shrinkable film maintains the adaptor blocked in rotation and in translation relative to the container when the heat-shrinkable film is in heat-shrunk condition.
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公开(公告)号：US11793723B2
公开(公告)日：2023-10-24
申请号：US17316052
申请日：2021-05-10
发明人： Martin Biehl , Michael Hock , Henrik Schaake , Ulla Schöbel , Holger Lenkeit , Marcel Borgward
CPC分类号： A61J3/002 , A61J2200/74 , B65B3/003
摘要： The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. The installation comprises a pump with which liquids can be transferred from a plurality of source containers into a target container. The installation has a modular construction and comprises a weighing module and a main module with the pump. According to a further aspect of the invention, the pump is arranged at an inclination with respect to a vertical plane. According to a further aspect of the invention, the installation comprises cascaded valve nodes.
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3.发明公开公开(公告)号：US20230294366A1
公开(公告)日：2023-09-21
申请号：US18199873
申请日：2023-05-19
发明人： Gerald Wegner , Jom Wittorf
CPC分类号： B29C65/38 , A61J1/10 , B29C65/224 , B29C65/226 , B29C66/1122 , B29C66/232 , B29C66/24244 , B29C66/244 , B29C66/346 , B29C66/43 , B29C66/53263 , B29C66/7352 , B29C66/73921 , B29C66/8122 , B29C66/81261 , B29C66/81427 , B29C66/81811 , B29C66/8322 , B29C66/91423 , B29K2023/06 , B29K2023/12
摘要： The invention relates to a welding tool and a method for pulse welding films of plastic for medical packs formed as bags. The invention generally provides for the film material that has been plastified during welding, and is consequently free-flowing, to be specifically displaced by increasing the sealing surface area. The displaced film material can for instance compensate for dimensional and form tolerances. At the same time, however, the strength of the welded seam region, which adjoins the interior space of the bag, is not reduced.
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公开(公告)号：US11752208B2
公开(公告)日：2023-09-12
申请号：US16990954
申请日：2020-08-11
IPC分类号： A61K39/395 , A61K9/00 , A61K47/18 , A61K47/26 , C07K16/24
CPC分类号： A61K39/39591 , A61K9/0019 , A61K47/183 , A61K47/26 , C07K16/241 , C07K2317/21 , C07K2317/76
摘要： The present invention relates to novel liquid pharmaceutical compositions of adalimumab, which include adalimumab or a biosimilar thereof, an histidine buffering agent such as histidine (or histidine buffer system such as histidine/imidiazolium-histidine), and a sugar stabiliser such as trehalose. Such a combination of components furnishes formulations having a stability (e.g. on storage and when exposed to stress) which is comparable to or an improvement upon those known in the art, and with fewer ingredients. Such advances will help adalimumab treatments to become more widely available at lower cost, and prolong the viability of pre-loaded delivery devices (e.g. pre-filled syringes) to reduce unnecessary waste of the drug.
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公开(公告)号：US11717608B1
公开(公告)日：2023-08-08
申请号：US17306533
申请日：2021-05-03
发明人： David R Schiff , Sharon D West , Justin Bechstein
CPC分类号： A61M5/14248 , A61M5/1413 , A61M2005/14268 , A61M2205/273 , A61M2205/3331
摘要： A drug delivery assembly is provided for delivering a medicament to a patient via a fluid flow path. The assembly includes a main body having a body housing with a body interface and a controller. The assembly also includes a cartridge having a cartridge housing with a cartridge interface configured to be removably associated to the body interface. A drug reservoir positioned within the cartridge housing is configured to contain a medicament and includes an outlet. An adhesive pad is associated with a surface of the cartridge housing and is configured to removably attach to a human body surface. The controller is configured to execute a drug delivery routine in which at least a portion of the medicament in the drug reservoir is delivered to a subject via the outlet and the fluid flow path when the main body is coupled to the cartridge.
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公开(公告)号：US11707524B2
公开(公告)日：2023-07-25
申请号：US17198983
申请日：2021-03-11
IPC分类号： A61K39/395 , A61K9/00 , A61K47/26 , C07K16/24 , A61K9/19 , A61K47/02 , A61K47/12 , A61K39/00
CPC分类号： A61K39/39591 , A61K9/0019 , A61K9/19 , A61K47/02 , A61K47/12 , A61K47/26 , C07K16/241 , A61K2039/505 , A61K2039/54 , C07K2317/21 , C07K2317/76
摘要： The present invention relates to novel liquid pharmaceutical compositions of adalimumab, which include adalimumab or a biosimilar thereof, an acetate buffering agent/system such as sodium acetate/acetic acid, and a sugar stabiliser such as trehalose. Such a combination of components furnishes formulations having a stability (e.g. on storage and when exposed to stress) which is comparable to or an improvement upon those known in the art, and with fewer ingredients. Such advances will help adalimumab treatments to become more widely available at lower cost, and prolong the viability of pre-loaded delivery devices (e.g. pre-filled syringes) to reduce unnecessary waste of the drug.
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7.发明授权公开(公告)号：US11673343B2
公开(公告)日：2023-06-13
申请号：US16493022
申请日：2018-03-23
发明人： Gerald Wegner , Jorn Wittorf
CPC分类号： B29C65/38 , A61J1/10 , B29C65/224 , B29C65/226 , B29C66/1122 , B29C66/232 , B29C66/244 , B29C66/24244 , B29C66/346 , B29C66/43 , B29C66/53263 , B29C66/7352 , B29C66/73921 , B29C66/8122 , B29C66/81261 , B29C66/81427 , B29C66/81811 , B29C66/8322 , B29C66/91423 , B29K2023/06 , B29K2023/12 , B29L2031/7148
摘要： The invention relates to a welding tool and a method for pulse welding films of plastic for medical packs formed as bags. The invention generally provides for the film material that has been plastified during welding, and is consequently free-flowing, to be specifically displaced by increasing the sealing surface area. The displaced film material can for instance compensate for dimensional and form tolerances. At the same time, however, the strength of the welded seam region, which adjoins the interior space of the bag, is not reduced.
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公开(公告)号：US11633537B1
公开(公告)日：2023-04-25
申请号：US17180594
申请日：2021-02-19
发明人： David R Schiff , Jason Zerweck
摘要： A drug delivery assembly includes a main body and a cartridge. The body includes a housing, an adhesive pad, and a body interface that detachably associates with a cartridge interface of the cartridge. A fluid flow path extends through the body housing, between a first end configured to open a seal of the cartridge and a second end configured to enter a human body. The cartridge contains a drug reservoir having an outlet and holding a medicament. The seal prevents the medicament from exiting the reservoir and maintains pressure within the reservoir until the seal is opened by the first end of the fluid flow path when the cartridge is coupled to the main body, placing the reservoir into fluid communication with the flow path. A controller actuates a valve within the body to selectively allow and prevent flow through the flow path during an automated drug delivery routine.
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公开(公告)号：US20230117587A1
公开(公告)日：2023-04-20
申请号：US18082732
申请日：2022-12-16
发明人： David R. Schiff , Justin Bechstein
IPC分类号： A61M5/142
摘要： An on-body drug delivery device having a housing carried by a substrate. The device includes an adhesive module placed over at least a portion of said device to provide added securement of the device to the patient's body.
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公开(公告)号：US11612578B2
公开(公告)日：2023-03-28
申请号：US16461616
申请日：2017-11-16
发明人： Edmundo Brito-De-La-Fuente , Ericka Pestana , Stephanie Reichart , Maria Fernanda Martinez-Bock , Sarah Ashley-Maguire , Jose Maria Mainou-Sierra
IPC分类号： A61K31/202 , A61P21/00 , A61K31/05 , A61K47/42 , A61K47/44 , A61K31/197 , A61K31/355 , A61K31/405 , A61K33/06
摘要： The invention relates to PUFA, vitamin E, vitamin D and the protein bound amino acids glycine, arginine and tryptophan as active ingredients for use in therapy of patients with sarcopenia and/or frailty or pre-sarcopenic and/or pre-frail patients, wherein an effective amount of said active ingredients is administered in the form of a nutritional composition comprising a) a lipid component providing 40-50 EN % based on the total energy of the nutritional composition, wherein 12-16 EN % based on the total energy of the nutritional composition is provided by PUFA, b) 4.0-8.0 mg/100 mL alpha-TE vitamin E, c) 5.0-12.0 μg/100 mL vitamin D, d) 2.5-4.5 g/100 mL glycine, e) 0.5-1.5 g/100 mL arginine, and f) at least 0.02 g/100 mL tryptophan.
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