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51.发明授权公开(公告)号：US07885449B2
公开(公告)日：2011-02-08
申请号：US12052898
申请日：2008-03-21
Applicant: Triantafyllos P. Tafas , Michael Kilpatrick , Petros Tsipouras
Inventor： Triantafyllos P. Tafas , Michael Kilpatrick , Petros Tsipouras
CPC classification number: G06K9/00147 , C12Q1/04 , G01N15/1475 , G06K9/00127 , G06T7/0012 , G06T2207/30024
Abstract: A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.
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52.发明申请公开(公告)号：US20090253145A1
公开(公告)日：2009-10-08
申请号：US12486709
申请日：2009-06-17
Applicant: Michael Kilpatrick , Triantafyllos Tafas
Inventor： Michael Kilpatrick , Triantafyllos Tafas
CPC classification number: C12Q1/6816 , C12Q1/6841 , G01N33/56966 , G01N33/689 , G01N33/721 , G01N2333/805 , G01N2800/385 , G02B21/367 , C12Q2563/107 , C12Q2537/143
Abstract: A method for detecting and quantitating multiple and unique fluorescent signals from a cell sample is provided. The method combines immunohistochemistry and a fluorescent-labeled in situ hybridization techniques. The method is useful for identifying specific subcellular components of cells such as chromosomes and proteins.
Abstract translation: 提供了一种从细胞样品中检测和定量多种独特荧光信号的方法。 该方法结合了免疫组织化学和荧光标记的原位杂交技术。 该方法可用于鉴定细胞如染色体和蛋白质的特定亚细胞组分。
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公开(公告)号：US20090250629A1
公开(公告)日：2009-10-08
申请号：US11833849
申请日：2007-08-03
Applicant: Young Min Kim , Yanning Zhu , Yash Agarwal , Xiuzhong Wang , Aaron Armstrong , Robert Borgerding , Andrew MacGinitie , Antti Seppo , Ilia Ichetovkin , Michael Kilpatrick , Petros Tsipouras , Triantafyllos Tafas
Inventor： Young Min Kim , Yanning Zhu , Yash Agarwal , Xiuzhong Wang , Aaron Armstrong , Robert Borgerding , Andrew MacGinitie , Antti Seppo , Ilia Ichetovkin , Michael Kilpatrick , Petros Tsipouras , Triantafyllos Tafas
CPC classification number: G01N35/00732 , G01J3/2803 , G01J3/4406 , G01N21/6428 , G01N21/6458 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6482 , G01N2035/00851 , G01N2201/06113 , G01N2201/12
Abstract: Operational means for automatic microscopic detection and analysis of fluorescent signals from a treated biological sample.
Abstract translation: 用于自动显微检测和分析来自经处理的生物样品的荧光信号的操作手段。
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54.发明申请公开(公告)号：US20090123054A1
公开(公告)日：2009-05-14
申请号：US12270820
申请日：2008-11-13
Applicant: Sir Walter Bodmer , Triantafyllos Tafas , Michael Kilpatrick , Petros Tsipouras , Xiuzhong Wang , Youngmin Kim , Michael Thomas , Antti Seppo , Triantafyllia Ntouroupi , Changhua Yu , Charles Climer
Inventor： Sir Walter Bodmer , Triantafyllos Tafas , Michael Kilpatrick , Petros Tsipouras , Xiuzhong Wang , Youngmin Kim , Michael Thomas , Antti Seppo , Triantafyllia Ntouroupi , Changhua Yu , Charles Climer
IPC: G06K9/00
CPC classification number: G06K9/00127 , G01N21/6458
Abstract: An automated, highly sensitive, specific and potentially quantitative detection method using an automated microscope for identifying and enumerating rare cancer cells in blood and other fluids.
Abstract translation: 一种使用自动显微镜识别和列举血液和其他液体中稀有癌细胞的自动化，高灵敏度，特异性和潜在的定量检测方法。
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Patent Agency Ranking
公开(公告)号：US07471079B2
公开(公告)日：2008-12-30
申请号：US11833203
申请日：2007-08-02
Applicant: Triantafyllos Tafas , Yash Agarwal , Youngmin Kim , Wei Guo , Richard Eberle , Joseph Turgeon , Michael Kilpatrick , Petros Tsipouras
Inventor： Triantafyllos Tafas , Yash Agarwal , Youngmin Kim , Wei Guo , Richard Eberle , Joseph Turgeon , Michael Kilpatrick , Petros Tsipouras
IPC: G01R31/302
CPC classification number: G02B21/24
Abstract: A light-tight enclosure system, displaceable along a surface, for housing an automated microscope, having electronically controllable components and an image capturing device. The enclosure system may include device for displacement, a shelf for placement of the automated microscope, an externally viewable monitor, and a plurality of electrical power receptacles.
Abstract translation: 一种不透光的外壳系统，可沿着表面移位，用于容纳自动显微镜，具有电子可控部件和图像捕获装置。 外壳系统可以包括用于移位的装置，用于放置自动显微镜的搁架，外部可观察的监视器和多个电力插座。
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公开(公告)号：US20080213902A1
公开(公告)日：2008-09-04
申请号：US11833760
申请日：2007-08-03
Applicant: Ilia Ichetovkin , Michael Kilpatrick
Inventor： Ilia Ichetovkin , Michael Kilpatrick
CPC classification number: C07B61/00 , C12Q1/6841 , Y10T436/10
Abstract: Improvements in FISH staining employing a microscope slide holder which allows for batch processing of slides in the hybridization process.
Abstract translation: 使用允许在杂交过程中批量处理载玻片的显微镜载玻片架进行FISH染色的改进。
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57.发明申请公开(公告)号：US20080182253A1
公开(公告)日：2008-07-31
申请号：US11924293
申请日：2007-10-25
Applicant: Triantafyllos P. Tafas , Petros Tsipouras , Michael Kilpatrick , Gary Sarkis
Inventor： Triantafyllos P. Tafas , Petros Tsipouras , Michael Kilpatrick , Gary Sarkis
IPC: C12Q1/68
CPC classification number: C12Q1/6841 , G01N21/6428 , G01N21/6458 , G01N33/57496 , G01N2021/6421 , G01N2021/6439 , G02B21/0004 , G02B21/16
Abstract: Automated methods for detecting cancer and related hyperplasias in biological samples.
Abstract translation: 用于检测生物样品中癌症和相关增生的自动化方法。
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公开(公告)号：US20080182244A1
公开(公告)日：2008-07-31
申请号：US11833678
申请日：2007-08-03
Applicant: Triantafyllos Tafas , Ilia Ichetovkin , Michael Kilpatrick , Petros Tsipouras
Inventor： Triantafyllos Tafas , Ilia Ichetovkin , Michael Kilpatrick , Petros Tsipouras
IPC: C12Q1/68
CPC classification number: G01N33/76 , C12Q1/6881 , C12Q1/6883 , C12Q2600/156
Abstract: A method for determining viable normal blastomeres for implantation entailing labeling the blastomere with an antibody to hyperglycoslyated hCG and determining the binding of chromosomal probes directed to chromosomal regions of the chromosome.
Abstract translation: 用于确定用于植入的活的正常卵裂球的方法，其需要用高糖化hCG的抗体标记所述卵裂球，并确定针对染色体的染色体区域的染色体探针的结合。
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59.发明申请Method for detecting infectious agents using computer controlled automated image analysis 审中-公开使用计算机控制的自动图像分析检测感染因子的方法公开(公告)号：US20060239533A1
公开(公告)日：2006-10-26
申请号：US10543270
申请日：2002-06-04
Applicant: Triantafyllos Tafas , Michael Kilpatrick , Petros Tsipouras
Inventor： Triantafyllos Tafas , Michael Kilpatrick , Petros Tsipouras
CPC classification number: G06K9/00147 , C12Q1/04 , G01N15/1475 , G06K9/00127 , G06T7/0012 , G06T2207/30024
Abstract: Computer controlled methods, systems and apparatus for detecting an infectious agent in a host cell, an animal cell, or plant cell, a body fluid or tissue sample to provide information useful to diagnose a disease or prognosticate disease susceptibility, extent or outcome are provided. In one illustrative embodiment, the infected animal cell is a Chlamydia infected mononuclear phagocyte in a blood sample. In another illustrative embodiment, the infected body fluid is a blood sample infected with “fee floating” Chlamydia. Detection and preferably, quantification of such an infected mononuclear phagocyte(s) or blood sample provides information useful in diagnosing or prognosticating susceptibility, extent or outcome of patients suspected of suffering from vascular, coronary or central nervous disease(s) or disorder(s).
Abstract translation: 提供了用于检测宿主细胞，动物细胞或植物细胞，体液或组织样本中的感染剂的计算机控制方法，系统和装置，以提供用于诊断疾病或预测疾病易感性，程度或结果的信息。 在一个说明性实施方案中，感染的动物细胞是血液样品中衣原体感染的单核吞噬细胞。 在另一说明性实施例中，感染的体液是感染“费用漂浮”衣原体的血液样本。 检测并优选地定量这种受感染的单核吞噬细胞或血液样品提供了可用于诊断或预测怀疑患有血管，冠状动脉或中枢神经疾病或病症的患者的易感性，程度或结果的信息， 。
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