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55 条记录 (耗时 0.022 秒)

    Medical devices incorporating carbon nanotube material and methods of fabricating same
    52.
    发明授权
    Medical devices incorporating carbon nanotube material and methods of fabricating same 有权
    纳入碳纳米管材料的医疗器械及其制造方法

    公开(公告)号：US07596415B2

    公开(公告)日：2009-09-29

    申请号：US11038731

    申请日：2005-01-20

    申请人： Scott J. Brabec ,  Kenneth C. Gardeski ,  Suping Lyu ,  James A. Coles, Jr. ,  Christopher M. Hobot

    发明人： Scott J. Brabec ,  Kenneth C. Gardeski ,  Suping Lyu ,  James A. Coles, Jr. ,  Christopher M. Hobot

    IPC分类号： A61N1/18 ,  A61N1/05

    CPC分类号： A61N1/056 ,  A61N1/0565 ,  Y10S977/905 ,  Y10S977/925 ,  Y10S977/931

    摘要： The present invention relates generally to medical devices; in particular and without limitation, to unique electrodes and/or electrical lead assemblies for stimulating cardiac tissue, muscle tissue, neurological tissue, brain tissue and/or organ tissue; to electrophysiology mapping and ablation catheters for monitoring and selectively altering physiologic conduction pathways; and, wherein said electrodes, lead assemblies and catheters optionally include fluid irrigation conduit(s) for providing therapeutic and/or performance enhancing materials to adjacent biological tissue, and wherein each said device is coupled to or incorporates nanostructure or materials therein. The present invention also provides methods for fabricating, deploying, and operating such medical devices.

    摘要翻译： 本发明一般涉及医疗器械; 特别是但不限于用于刺激心脏组织，肌肉组织，神经组织，脑组织和/或器官组织的独特电极和/或电引线组件; 用于电生理测绘和消融导管，用于监测和选择性地改变生理传导途径; 并且其中所述电极，引线组件和导管可选地包括用于向相邻生物组织提供治疗和/或性能增强材料的流体冲洗导管，并且其中每个所述装置与其中的纳米结构或材料耦合或结合。 本发明还提供了制造，部署和操作这种医疗装置的方法。

    Benzodiazepine Formulation in a Polyorthoester Carrier
    53.
    发明申请
    Benzodiazepine Formulation in a Polyorthoester Carrier 有权
    苯二氮卓配方在聚原酸酯载体中的应用

    公开(公告)号：US20090202604A1

    公开(公告)日：2009-08-13

    申请号：US12426031

    申请日：2009-04-17

    申请人： Christopher M. Hobot ,  Michael E. Benz ,  Keith R. Hildebrand ,  Bryant J. Pudil

    发明人： Christopher M. Hobot ,  Michael E. Benz ,  Keith R. Hildebrand ,  Bryant J. Pudil

    IPC分类号： A61F13/00 ,  A61K31/551

    CPC分类号： A61K31/197 ,  A61K9/0024 ,  A61K47/34

    摘要： Effective treatments of pain for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an effective amount of a benzodiazepine, such as midazolam, formulated within a polyorthoester. By administration of one or more drug depots, one can relieve pain caused by diverse sources, including but not limited to chronic pelvic pain syndromes, spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days or at least one hundred and thirty-five days.

    摘要翻译： 提供长时间有效的疼痛治疗。 治疗方法包括给药一种或多种药物贮库，其中药物贮库包括配制在聚原酸酯内的有效量的苯二氮卓类，如咪达唑仑。 通过管理一个或多个药物库，可以减轻由多种来源引起的疼痛，包括但不限于慢性盆腔疼痛综合征，椎间盘突出症（即坐骨神经痛），脊椎脱位，狭窄，恶性背痛和关节疼痛，以及 手术附带的疼痛。 在一些实施方案中，缓解可以是至少二十五天，至少五十天，至少一百天或至少一百三十五天。