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    STANNOUS SALT AND SODIUM TRIPOLYPHOSPHATE ORAL CARE COMPOSITIONS AND METHODS
    51.
    发明申请
    STANNOUS SALT AND SODIUM TRIPOLYPHOSPHATE ORAL CARE COMPOSITIONS AND METHODS 审中-公开
    STANNOUS SALT和SODIUM三磷酸盐口腔护理组合物和方法

    公开(公告)号：US20150086492A1

    公开(公告)日：2015-03-26

    申请号：US14560168

    申请日：2014-12-04

    Applicant: Colgate-Palmolive Company

    Inventor： James R. Brown ,  Linh Fruge ,  Tao Xu ,  Michael Prencipe

    IPC: A61K8/69 ,  A61Q11/00 ,  A61K8/55

    CPC classification number: A61K8/21 ,  A61K8/03 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/25 ,  A61K8/55 ,  A61K8/69 ,  A61K8/8164 ,  A61K2800/28 ,  A61K2800/591 ,  A61Q11/00

    Abstract: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1 of the compositions. Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) prior to dental care usage.

    Abstract translation: 提供含有亚锡盐和三聚磷酸钠的口腔护理组合物，其中三聚磷酸三钠离子中间体包含少于约1种组合物。 可以加入焦磷酸四钠，甲基乙烯基醚 - 马来酸酐共聚物和/或二氧化硅口腔抛光剂以获得更高的效力。 在单相共混物中，口腔护理组合物可以有效地限制为包含小于约10％的水。 在双相共混物中，在牙齿保健使用之前，可以从双室存储管（每个相位由独立的室提供）产生具有第一相中的亚锡盐和第二相中的三聚磷酸钠的混合物。

    HYDROPHOBIC TOOTH WHITENING SYSTEM AND METHODS OF USE
    52.
    发明申请
    HYDROPHOBIC TOOTH WHITENING SYSTEM AND METHODS OF USE 审中-公开
    疏水牙膏白色系统及其使用方法

    公开(公告)号：US20140335028A1

    公开(公告)日：2014-11-13

    申请号：US14338319

    申请日：2014-07-22

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： Michael Prencipe ,  Suman K. Chopra ,  Michael Collins

    IPC: A61K8/89 ,  A61K8/22 ,  A61Q11/00

    CPC classification number: A61K8/89 ,  A61C19/066 ,  A61K8/22 ,  A61K8/8176 ,  A61K8/891 ,  A61K8/895 ,  A61Q11/00

    Abstract: A tooth whitening system comprising a dental tray having a surface operable to confront a tooth surface, and a tooth whitening composition comprising a whitening agent and a hydrophobic polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. A tooth whitening kit is also provided using a dental tray and the tooth whitening composition comprising a whitening composition and a hydrophobic polymer carrier.

    Abstract translation: 一种牙齿美白系统，其包括具有可操作以面对牙齿表面的表面的牙托盘，和包含增白剂和疏水性聚合物载体的牙齿增白组合物。 牙齿美白组合物优选基本上是非水溶性的。 还使用牙科托盘和含有美白组合物和疏水性聚合物载体的牙齿增白组合物来提供牙齿美白试剂盒。

    ORAL CARE COMPOSITION
    53.
    发明申请
    ORAL CARE COMPOSITION 审中-公开
    口腔护理组合物

    公开(公告)号：US20140120041A1

    公开(公告)日：2014-05-01

    申请号：US14147826

    申请日：2014-01-06

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： Michael Prencipe ,  Andre Morgan ,  Venda Porter Maloney

    IPC: A61K8/02 ,  A61K8/19 ,  A61K8/29 ,  A61Q11/00 ,  A61K8/27

    CPC classification number: A61K8/27 ,  A61K8/0245 ,  A61K8/19 ,  A61K8/29 ,  A61K8/44 ,  A61K8/731 ,  A61K2800/412 ,  A61K2800/5922 ,  A61K2800/594 ,  A61K2800/624 ,  A61Q11/00

    Abstract: Disclosed are oral care compositions, for example dentifrice compositions, comprising an oral care composition comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and at least one amino acid capable of chelating the metal oxide. The composition may comprise a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.

    Abstract translation: 公开了口腔护理组合物，例如洁牙剂组合物，其包含口腔护理组合物，其包含口腔可接受的载体，平均粒度不大于牙本质小管的金属氧化物颗粒和能够螯合金属氧化物的至少一种氨基酸。 组合物可以包含用于将金属氧化物颗粒粘附在牙本质小管中的聚合物粘附材料。 金属氧化物颗粒的中值粒径为5微米以下，可以含有氧化锌。

    ABRASIVE SYSTEM FOR ORAL CARE COMPOSITIONS
    54.
    发明申请
    ABRASIVE SYSTEM FOR ORAL CARE COMPOSITIONS 审中-公开
    用于口腔护理组合物的磨砂系统

    公开(公告)号：US20130195942A1

    公开(公告)日：2013-08-01

    申请号：US13732804

    申请日：2013-01-02

    Applicant: Colgate-Palmolive Company

    Inventor： Michael Prencipe ,  Sayed Ibrahim

    IPC: A61K8/18 ,  A61Q11/00

    CPC classification number: A61K8/18 ,  A61K8/25 ,  A61K8/347 ,  A61K2800/28 ,  A61K2800/412 ,  A61K2800/59 ,  A61K2800/5922 ,  A61Q11/00

    Abstract: Oral compositions comprising a first and a second abrasive are provided. The first abrasive preferably has an Einlehner hardness of greater than about 5 mg loss per 100,000 revolutions, and the second abrasive preferably has an Einlehner hardness of less than about 5 mg loss per 100,000 revolutions. A ratio of the first abrasive to the second abrasive ranges from about 1:1.6 to about 1.6:1, and the first and second abrasives are preferably present in the oral composition at an amount of about 13% to about 21% by weight, respectively. The pellicle cleaning ratio of the oral composition is greater than 100 and the radioactive dentin abrasiveness is preferably less than 200, and in certain embodiments, preferably less than about 175. Methods of using the oral compositions are also provided.

    Abstract translation: 提供包含第一和第二研磨剂的口腔组合物。 第一研磨剂优选具有每100,000转大于约5毫克损失的艾因纳氏硬度，并且第二磨料优选具有每100,000转小于约5毫克损失的埃因纳氏硬度。 第一研磨剂与第二研磨剂的比例为约1:1.6至1.6:1，第一和第二研磨剂分别以约13重量％至约21重量％的量存在于口腔组合物中 。 口腔组合物的防护薄膜清洁率大于100，并且放射性牙本质磨蚀性优选小于200，在某些实施方案中优选小于约175.还提供使用口腔组合物的方法。

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