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    [1,2,4]TRIAZOLO[4,3-B][1,2,4]TRIAZINE COMPOUNDS, PREPARATION METHOD AND USE THEREOF
    51.
    发明申请
    [1,2,4]TRIAZOLO[4,3-B][1,2,4]TRIAZINE COMPOUNDS, PREPARATION METHOD AND USE THEREOF 审中-公开
    [1,2,4]三唑[4,3-B] [1,2,4]三嗪化合物，其制备方法及其用途

    公开(公告)号：US20130324542A1

    公开(公告)日：2013-12-05

    申请号：US13992048

    申请日：2011-12-08

    申请人： Wenhu Duan ,  Meiyu Geng ,  Fang Chen ,  Jing Ai ,  Yi Chen ,  Zhengsheng Zhan ,  Yongcong Lv ,  Ying Wang ,  Jian Ding

    发明人： Wenhu Duan ,  Meiyu Geng ,  Fang Chen ,  Jing Ai ,  Yi Chen ,  Zhengsheng Zhan ,  Yongcong Lv ,  Ying Wang ,  Jian Ding

    IPC分类号： C07D487/04

    CPC分类号： C07D487/04

    摘要： The present invention relates to a structurally novel [1,2,4]triazolo[4,3-b][1,2,4]triazine compounds represented by formula (I) or formula (II), pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates or solvates thereof, and also relates to a preparation method of the compounds, a pharmaceutical composition including a therapeutically effective amount of the compounds, as well as the use thereof as protein tyrosine kinase inhibitors, particularly as c-Met inhibitors, in the preparation of medicaments for the prevention and/or treatment of diseases associated with c-Met abnormality.

    摘要翻译： 本发明涉及由式（I）或式（II）表示的结构上新的[1,2,4]三唑并[4,3-b] [1,2,4]三嗪化合物，其药学上可接受的盐，前体药物 其还涉及本发明化合物的制备方法，包含治疗有效量的化合物的药物组合物，以及其作为蛋白酪氨酸激酶抑制剂，特别是作为c-Met抑制剂的用途， 制备用于预防和/或治疗与c-Met异常有关的疾病的药物。

    Tower barrel, wind tower and wind power plant for wind electric power generation
    52.
    发明授权
    Tower barrel, wind tower and wind power plant for wind electric power generation 有权
    风力发电塔塔，风塔和风力发电厂

    公开(公告)号：US08578676B2

    公开(公告)日：2013-11-12

    申请号：US13501777

    申请日：2010-10-25

    申请人： Jizhuang Lu ,  Qin Zhang ,  Fang Chen ,  Huimin He

    发明人： Jizhuang Lu ,  Qin Zhang ,  Fang Chen ,  Huimin He

    IPC分类号： E04H12/00

    CPC分类号： F03D13/20 ,  F03D80/85 ,  Y02E10/728

    摘要： A tower barrel for wind electric power generation includes a barrel wall for supporting a wind turbine generator system, a torsion cable direction-changing device which is placed in the tower barrel and fixed on the barrel wall for holding the cable from the wind turbine generator system and restraining the torsion of the cable, and cable clamps which are placed under the torsion cable direction-changing device and connected to the barrel wall for securing the cable. The torsion cable direction-changing device includes a beam and two supports for the beam, the supports are fixed on the barrel wall. The torsion cable direction-changing device in the tower barrel improves the safety of the cable, and so improves the safety of the wind turbine generator system.

    摘要翻译： 用于风力发电的塔筒包括用于支撑风力涡轮发电机系统的桶壁，扭转线缆方向改变装置，其被放置在塔筒中并固定在筒壁上，用于将风力涡轮发电机系统 并且限制电缆的扭转，以及放置在扭转线缆方向改变装置下方并连接到筒壁以用于固定电缆的电缆夹。 扭转线缆方向改变装置包括一个梁和两个用于梁的支撑件，支撑件固定在筒壁上。 塔筒扭力线方向改变装置提高了电缆的安全性，从而提高了风力发电机组的安全性。

    VERIFYING A USER
    53.
    发明申请
    VERIFYING A USER 有权
    验证用户

    公开(公告)号：US20130185071A1

    公开(公告)日：2013-07-18

    申请号：US13551313

    申请日：2012-07-17

    申请人： Fang Chen ,  Bo Yin ,  Kim MacDonald

    发明人： Fang Chen ,  Bo Yin ,  Kim MacDonald

    IPC分类号： G10L17/04

    CPC分类号： G10L17/04 ,  G06F21/32 ,  G06K9/00892 ,  G06K9/6297

    摘要： Verifying a user, such as, but not limited to, a user who answered questions for an unproctered test for employment. A representation of a transition pattern is stored (200). Time series voice data is received from a user responding to a sequence of questions (72) having multiple levels of difficulty. The transition pattern in the voice data (200) is based on a plurality of comparisons (503) of subsets (500) of the voice data corresponding to responses to questions having one or more different levels of difficulty. A further transition pattern (200) is determined from voice data in the same way but based on a shorter sequence of questions (78). The user is verified based on a comparison (78) of this further transition pattern to a previously stored transition pattern.

    摘要翻译： 验证用户，例如但不限于回答未经规定的就业测试问题的用户。 存储过渡模式的表示（200）。 响应于具有多个难度级别的问题序列（72），从用户接收时间序列语音数据。 语音数据（200）中的转换模式基于对应于对具有一个或多个不同难度级别的问题的响应的语音数据的子集（500）的多个比较（503）。 另一转换模式（200）以相同的方式从语音数据确定，但是基于较短的问题序列（78）。 基于此另外的转换模式与先前存储的转换模式的比较（78）来验证用户。

    Protective circuits for secondary battery packs
    55.
    发明授权
    Protective circuits for secondary battery packs 有权
    二次电池组的保护电路

    公开(公告)号：US07701176B2

    公开(公告)日：2010-04-20

    申请号：US11636141

    申请日：2006-12-07

    申请人： Fang Chen

    发明人： Fang Chen

    IPC分类号： H02J7/04

    CPC分类号： H02J7/0031 ,  H02J2007/0037 ,  H02J2007/0039

    摘要： This invention discloses a charging/discharging protective circuit for a secondary battery pack, having an over-charging/discharging voltage comparator, a reference voltage source and a battery status decision circuit. There is also a sampling circuit having a sequential pulse generator for generating pulses for selecting one of the batteries in the battery pack for testing purposes. The pulse generator provides M-channel gating pulses to the selection circuit of the battery under test and provides sampling pulses to the over-charging/discharging voltage comparators. The reference voltage source has a regulated output circuit. This invention uses time division inspection methods to provide a cost-effective solution for inspecting batteries in a battery pack.

    摘要翻译： 本发明公开了一种具有过充电/放电电压比较器，参考电压源和电池状态判定电路的二次电池组的充放电保护电路。 还有一个具有顺序脉冲发生器的采样电路，用于产生用于选择电池组中的一个电池用于测试目的的脉冲。 脉冲发生器向被测电池的选择电路提供M通道门控脉冲，并向过充电/放电电压比较器提供采样脉冲。 参考电压源具有稳压输出电路。 本发明使用时分检查方法来提供用于检查电池组中的电池的成本有效的解决方案。

    PROTECTIVE CIRCUITS FOR SECONDARY BATTERY PACKS
    57.
    发明申请
    PROTECTIVE CIRCUITS FOR SECONDARY BATTERY PACKS 有权
    二次电池组保护电路

    公开(公告)号：US20090315517A1

    公开(公告)日：2009-12-24

    申请号：US12096363

    申请日：2006-12-07

    申请人： Fang Chen

    发明人： Fang Chen

    IPC分类号： H02J7/00

    CPC分类号： H02J7/0031 ,  H02J2007/0037 ,  H02J2007/0039

    摘要： This invention discloses a charging/discharging protective circuit for a secondary battery pack, having an over-charging/discharging voltage comparator, a reference voltage source and a battery status decision circuit. There is also a sampling circuit having a sequential pulse generator for generating pulses for selecting one of the batteries in the battery pack for testing purposes. The pulse generator provides M-channel gating pulses to the selection circuit of the battery under test and provides sampling pulses to the over-charging/discharging voltage comparators. The reference voltage source has a regulated output circuit. This invention uses time division inspection methods to provide a cost-effective solution for inspecting batteries in a battery pack.

    摘要翻译： 本发明公开了一种二次电池组的充放电保护电路，具有过充电/放电电压比较器，参考电压源和电池状态判定电路。 还有一个具有顺序脉冲发生器的采样电路，用于产生用于选择电池组中的一个电池用于测试目的的脉冲。 脉冲发生器向被测电池的选择电路提供M通道门控脉冲，并向过充电/放电电压比较器提供采样脉冲。 参考电压源具有稳压输出电路。 本发明使用时分检查方法来提供用于检查电池组中的电池的成本有效的解决方案。

    MULTIMODAL COMPUTER NAVIGATION
    58.
    发明申请
    MULTIMODAL COMPUTER NAVIGATION 审中-公开
    多模式计算机导航

    公开(公告)号：US20090049388A1

    公开(公告)日：2009-02-19

    申请号：US11916255

    申请日：2006-06-02

    申请人： Ronnie Bernard Francis Taib ,  Fang Chen ,  Yu Shi

    发明人： Ronnie Bernard Francis Taib ,  Fang Chen ,  Yu Shi

    IPC分类号： G06F3/00

    CPC分类号： G06F3/038 ,  G06F16/95 ,  G06F2203/0381

    摘要： This invention concerns multimodal computer navigation, that is operation of a computer using traditional modes such as keyboard together with less conventional modes such as speech and gestures. The invention has particular application for navigation of information presentations, such as webpages and database user interfaces, and is presented as a method, a browser, software and a computer system. The information navigated is not described in a multimodal way. Two or more unimodal navigation signals are received from a user and interpreted. These interpretations are fused to automatically determining the user's intended navigation selection.

    摘要翻译： 本发明涉及多模式计算机导航，即使用诸如键盘之类的传统模式的计算机的操作以及较少传统的模式，例如语音和手势。 本发明具有用于诸如网页和数据库用户界面的信息呈现的导航的特定应用，并且被呈现为方法，浏览器，软件和计算机系统。 导航的信息不以多模态方式描述。 从用户接收到两个或多个单峰导航信号并进行解释。 这些解释融合以自动确定用户的预期导航选择。

    Method for identifying androgen receptor modulators with full or mixed agonist activity
    60.
    发明申请
    Method for identifying androgen receptor modulators with full or mixed agonist activity 审中-公开
    用于鉴定具有完全或混合激动剂活性的雄激素受体调节剂的方法

    公开(公告)号：US20070141636A1

    公开(公告)日：2007-06-21

    申请号：US10580285

    申请日：2004-11-19

    申请人： Fang Chen

    发明人： Fang Chen

    IPC分类号： G01N33/567

    CPC分类号： G01N33/57434 ,  G01N33/743 ,  G01N2500/00 ,  G01N2500/10

    摘要： A method for identifying androgen receptor (AR) modulators which have full AR agonist or antagonist activity or mixed AR agonist activity is described. In one aspect of the invention, an analyte with mixed AR agonist activity is identified by comparing binding of the analyte to a human AR to its binding to the ligand binding domain (LBD) of the rhesus monkey AR (or other non-human AR) wherein a difference in binding indicates the analyte likely has mixed agonist activity. In a further aspect of the method, the ratio of AR agonist to AR antagonist activity of the analyte with the mixed AR agonist activity is determined by the effect of the analyte on PSA production in a prostrate cancer cell line in the presence and absence of a known full AR agonist. In a further still aspect of the method, analytes which have full AR agonist or antagonist activity are identified by the effect of the analyte on PSA production in a prostrate cancer cell line in the presence and absence of a known full AR agonist. The present invention is particularly useful for identifying analytes which are selective androgen receptor modulators (SARMs).

    摘要翻译： 描述了具有完全AR激动剂或拮抗剂活性或混合AR激动剂活性的确定雄激素受体（AR）调节剂的方法。 在本发明的一个方面，具有混合AR激动剂活性的分析物通过将分析物与人AR的结合与其与恒河猴AR（或其他非人AR）的配体结合结构域（LBD）的结合进行鉴定， 其中结合的差异表明分析物可能具有混合的激动剂活性。 在该方法的另一方面，AR激动剂与具有混合AR激动剂活性的分析物的AR拮抗剂活性的比例通过分析物在前列腺癌细胞系中在PSA存在和不存在下的PSA产生的作用来确定 已知全AR激动剂。 在该方法的另一方面，在存在和不存在已知的全AR激动剂的情况下，通过分析物对前列腺癌细胞系中PSA产生的影响来鉴定具有完全AR激动剂或拮抗剂活性的分析物。 本发明特别可用于鉴定作为选择性雄激素受体调节剂（SARM）的分析物。