公开(公告)号：US4999440A

公开(公告)日：1991-03-12

申请号：US395233

申请日：1989-08-17

申请人： Graham Holmwood ,  Udo Kraatz ,  Karl H. Buchel ,  Wilhelm Brandes ,  Stefan Dutzmann ,  Paul Reinecke

发明人： Graham Holmwood ,  Udo Kraatz ,  Karl H. Buchel ,  Wilhelm Brandes ,  Stefan Dutzmann ,  Paul Reinecke

IPC分类号： A01N43/653 ,  C07C15/44 ,  C07C25/24 ,  C07D249/08 ,  C07D303/06 ,  C07D303/08 ,  C07D303/22 ,  C07D303/34 ,  C07D303/36 ,  C07D521/00

CPC分类号： C07D249/08 ,  A01N43/653 ,  C07C15/44 ,  C07C25/24 ,  C07D231/12 ,  C07D233/56 ,  C07D303/08

摘要： Fungicidal hydroxyalkyl-triazdyl derivatives of the formula ##STR1## in which R represents a radical of the formula --CH.sub.2 --CH(CH.sub.3).sub.2, --(CH.sub.2).sub.4 --CH.sub.3, --(CH.sub.2).sub.5 --CH.sub.3, --(CH.sub.2).sub.6 --CH.sub.3, ##STR2## Z represents halogen, alkyl with 1 to 4 carbon atoms, halogenoalkyl with 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkoxy with 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkylthio with 1 or 2 carbon atoms and 1 to 5 halogen atoms, phenyl or alkoximinimethyl with 1 to 4 carbon atoms in the alkoxy group andm represents the numbers 0, 1, 2 or 3,and addition products thereof with acids and metal salts. Intermediates of the formulas ##STR3## are also new.

公开(公告)号：US4960453A

公开(公告)日：1990-10-02

申请号：US190601

申请日：1988-05-05

申请人： Graham Holmwood ,  Gerhard Jager ,  Karl H. Buchel ,  Wilhelm Brandes ,  Stefan Dutzmann ,  Gerd Hanssler

发明人： Graham Holmwood ,  Gerhard Jager ,  Karl H. Buchel ,  Wilhelm Brandes ,  Stefan Dutzmann ,  Gerd Hanssler

IPC分类号： A01N43/653 ,  C07C25/24 ,  C07D249/08 ,  C07D303/08 ,  C07D303/22 ,  C07D303/34 ,  C07D521/00

CPC分类号： C07D303/22 ,  A01N43/653 ,  C07C25/24 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D303/08

摘要： Fungicidal and plant growth-regulating hydroxyalkylazolyl derivatives of the formula ##STR1## in which Z represents halogen, alkyl with 1 to 4 carbon atoms, halogenoalkyl with 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkoxy with 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkylthio with 1 or 2 carbon atoms and 1 to 5 halogen atoms, phenyl or alkoximinomethyl with 1 to 4 carbon atoms in the alkoxy group,X represents oxygen, sulphur or a CH.sub.2 group andm represents the number 0, 1, 2 or 3,and addition products thereof with acids and metal salts. Intermediates of the formulas ##STR2## are also new.

摘要翻译： 其中Z表示卤素，具有1至4个碳原子的烷基，1或2个碳原子的卤代烷基和1至5个卤素原子的式（I）的杀真菌剂和植物生长调节羟烷基唑基衍生物，1或2个卤代烷氧基 碳原子和1至5个卤素原子，具有1或2个碳原子和1至5个卤素原子的卤代烷硫基，烷氧基中具有1至4个碳原子的苯基或烷氧基甲基，X表示氧，硫或CH2基，m表示 数字0,1,2或3，及其与酸和金属盐的加成产物。 式（II）和（IMA）（VI）的中间体也是新的。

公开(公告)号：US4904296A

公开(公告)日：1990-02-27

申请号：US121552

申请日：1987-11-17

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D303/22 ,  C07D303/34 ,  C07D405/06 ,  C07D521/00

CPC分类号： C07D303/22 ,  A01N43/50 ,  A01N43/653 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are substituted 1-hydroxyalkylazolyl derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R represents substituted alkyl, and, in the case in which B represents sulphur, also represents an unsubstituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl group, Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy group, andm is 0, 1, 2 or 3,and the acid addition salts and metal salt complexes thereof, are new, are prepared as described and find use as fungicides and plant growth regulators.

公开(公告)号：US4878939A

公开(公告)日：1989-11-07

申请号：US258108

申请日：1988-10-13

申请人： Gerhard Jager ,  Manfred Jautelat ,  Wolfgang Kramer ,  Karl H. Buchel ,  Paul Reinecke ,  Wilhelm Brandes ,  Gerd Hanssler ,  Klaus Lurssen

发明人： Gerhard Jager ,  Manfred Jautelat ,  Wolfgang Kramer ,  Karl H. Buchel ,  Paul Reinecke ,  Wilhelm Brandes ,  Gerd Hanssler ,  Klaus Lurssen

IPC分类号： C07C43/225 ,  A01N43/50 ,  A01N43/653 ,  C07C41/00 ,  C07C45/00 ,  C07C49/167 ,  C07C49/175 ,  C07C67/00 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Azolyl ether ketones and alcohols of the formula ##STR1## in which R.sup.1 and R.sup.2 each independently represents alkyl with more than one carbon atom, orR.sup.1 represents dichloromethyl, trichloromethyl, chlorovinyl or dichlorovinyl, andR.sup.2 represents alkyl,R.sup.3 represents alkyl,A represents the keto group or a CH(OH) grouping,Z represents a nitrogen atom or the CH group,X represents oxygen or sulphur andAr represents optionally substituted phenyl,or addition products thereof with acids and metal salts, are active against fungi and in regulating the growth of plants. New intermediates therefor are also shown.

摘要翻译： 其中R 1和R 2各自独立地表示具有多于一个碳原子的烷基，或者R 1表示二氯甲基，三氯甲基，氯乙烯基或二氯乙烯基，并且R 2表示烷基，R 3表示烷基， 酮基或CH（OH）基，Z表示氮原子或CH基，X表示氧或硫，Ar表示任选取代的苯基，或其与酸和金属盐的加成产物对真菌有活性， 植物生长。 还显示了其新的中间体。

公开(公告)号：US4875928A

公开(公告)日：1989-10-24

申请号：US792089

申请日：1985-10-28

申请人： Erik Regel ,  Klaus Bockmann ,  Karl H. Buchel ,  Klaus Lurssen ,  Wilhelm Brandes ,  Jorg Konze ,  Paul Reinecke

发明人： Erik Regel ,  Klaus Bockmann ,  Karl H. Buchel ,  Klaus Lurssen ,  Wilhelm Brandes ,  Jorg Konze ,  Paul Reinecke

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D333/00 ,  C07D403/06 ,  C07D405/06 ,  C07D409/06 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08 ,  Y02P60/246

摘要： Substituted azolylcyclopropyl-azolylmethyl-carbinol derivatives of the formula ##STR1## in which Ar is optionally substituted aryl or optionally substituted heteroaryl,R is hydrogen, alkyl, alkenyl, alkinyl, trialkylsilyl, optionally substituted phenylalkyl or an acyl radical, andX and Y each independently is a nitrogen atom or a CH group,and addition products thereof with acids and metal salts are effective in regulating plant growth and combating fungi. New intermediates are described, some of which are themselves active.

摘要翻译： 其中Ar是任选取代的芳基或任选取代的杂芳基，R是氢，烷基，烯基，炔基，三烷基甲硅烷基，任选取代的苯基烷基或酰基，以及X和Y各自独立地取代的具有式“IMAGE”的唑基环丙基 - 甲基 - 甲醇衍生物 独立地是氮原子或CH基团，其与酸和金属盐的加成产物在调节植物生长和对抗真菌中是有效的。 描述了新的中间体，其中一些本身是活性的。

公开(公告)号：US4868196A

公开(公告)日：1989-09-19

申请号：US859276

申请日：1986-05-02

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Klaus Lurssen

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Klaus Lurssen

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are ether derivatives of substituted 1-hydroxyalkyl-azoles, of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R.sup.1 represents a substituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl radical or, if either A represents a nitrogen atom, or if A represents the CH group and at the same B represents oxygen or sulphur, R.sup.1 also represents an unsubstituted alkyl radical,R.sup.2 represents an alkyl, alkenyl, alkinyl, optionally substituted phenyl or optionally substituted benzyl radical,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy radical andm is 0, 1, 2 or 3,and acid addition salts and metal salt complexes thereof, are novel, are prepared as described, and find use as fungicides and as agents for regulating plant growth.

摘要翻译： 作为其中A表示氮原子或CH基团的通式为：（I）的取代的1-羟基烷基 - 唑的醚衍生物的化合物，B表示氧，硫或CH2基，R1表示取代的烷基 ，任选取代的环烷基或任选取代的苯基，或者如果A表示氮原子，或者如果A表示CH基团，而相同的B表示氧或硫，则R1还表示未取代的烷基，R2表示烷基，烯基 烷氧基，烷硫基，卤代烷基，卤代烷氧基，卤代烷硫基，任选取代的苯氧基，任意取代的苯基烷基或任意取代的苯基烷氧基，m为0， 1,2或3及其酸加成盐和金属盐络合物是新颖的，按照所述制备，可用作杀真菌剂和如年龄 用于调节植物生长。

公开(公告)号：US4797499A

公开(公告)日：1989-01-10

申请号：US895089

申请日：1986-08-11

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D303/22 ,  C07D303/34 ,  C07D405/06 ,  C07D521/00 ,  C07D303/08

CPC分类号： C07D303/22 ,  A01N43/50 ,  A01N43/653 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are substituted 1-hydroxyalkyl-azolyl derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R represents substituted alkyl, and, in the case in which B represents sulphur, also represents an unsubstituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl group,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy group, andm is 0, 1, 2 or 3,and the acid addition salts and metal salt complexes thereof, are new, are prepared as described and find use as fungicides and plant growth regulators.

摘要翻译： 化合物，其中A表示氮原子或CH基团，B表示氧，硫或CH2基团，其中R表示取代的烷基，且表示取代的烷基， B代表硫的情况也代表未取代的烷基，任选取代的环烷基或任选取代的苯基，Z代表卤素原子或烷基，环烷基，烷氧基，烷硫基，卤代烷基，卤代烷氧基，卤代烷硫基，任选取代的苯基， 苯氧基，任选取代的苯基烷基或任选取代的苯基烷氧基，m为0,1,2或3，其酸加成盐和金属盐络合物是新的，如上所述制备，可用作杀真菌剂和植物生长调节剂。

公开(公告)号：US4723984A

公开(公告)日：1988-02-09

申请号：US621968

申请日：1984-06-18

申请人： Graham Holmwood ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes

发明人： Graham Holmwood ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes

IPC分类号： A01N20060101 ,  A01N43/20 ,  A01N43/50 ,  A01N43/64 ,  A01N43/653 ,  C07D20060101 ,  C07D233/60 ,  C07D249/08 ,  C07D301/00 ,  C07D301/02 ,  C07D303/02 ,  C07D303/04 ,  C07D303/08 ,  C07D303/20 ,  C07D303/22 ,  C07D521/00 ,  A61K31/41

CPC分类号： A01N43/50 ,  A01N43/653 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D303/02 ,  C07D303/04 ,  C07D303/08 ,  C07D303/22

摘要： New 1-hydroxyethyl-azole derivatives of the general formula ##STR1## in which R represents an alkyl radical, an optionally substituted cycloalkyl radical or an optionally substituted phenyl radical,X represents a nitrogen atom or a CH group,Y represents a grouping --OCH.sub.2 --, -- CH.sub.2 CH.sub.2 -- or --CH.dbd.CH--,Z represents a halogen atom, an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy or halogenoalkylthio radical, an optionally substituted phenyl radical, an optionally substituted phenoxy radical, an optionally substituted phenylalkyl radical or an optionally substituted phenylalkoxy radical andm is 0, 1, 2 or 3,a process for their preparation and their use as plant growth regulators and fungicides.

摘要翻译： 其中R表示烷基，任选取代的环烷基或任选取代的苯基的新的1-羟乙基 - 唑衍生物，其中R表示氮原子或CH基团，Y表示 分组-OCH 2 - ， - CH 2 CH 2 - 或-CH = CH-，Z表示卤素原子，烷基，环烷基，烷氧基，烷硫基，卤代烷基，卤代烷氧基或卤代烷硫基，任选取代的苯基，任选取代的苯氧基， 任选取代的苯基烷基或任选取代的苯基烷氧基，m为0,1,2或3，其制备方法及其用作植物生长调节剂和杀真菌剂。

公开(公告)号：US4622335A

公开(公告)日：1986-11-11

申请号：US645464

申请日：1984-09-11

申请人： Wolfgang Kramer ,  Karl H. Buchel ,  Graham Holmwood ,  Paul Reinecke ,  Wilhelm Brandes

发明人： Wolfgang Kramer ,  Karl H. Buchel ,  Graham Holmwood ,  Paul Reinecke ,  Wilhelm Brandes

IPC分类号： C07D249/08 ,  A01N43/50 ,  A01N43/56 ,  A01N43/653 ,  C07C45/43 ,  C07C45/51 ,  C07C45/63 ,  C07C49/255 ,  C07D20060101 ,  C07D233/60 ,  C07D233/61 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07C45/43 ,  C07C45/515 ,  C07C45/63 ,  C07C49/255 ,  C07D233/56 ,  C07D249/08

摘要： Fungicidally active novel hydroxyethylazolyl-oxime derivatives of the formula ##STR1## in which Ar is optionally substituted aryl,R.sup.1 is hydrogen or alkyl,R.sup.2 is hydrogen, alkyl, alkenyl, alkinyl, optionally substituted aralkyl or optionally substituted cycloalkylalkyl, andX is a nitrogen atom or the CH group,and addition products thereof with acids and metal salts.

摘要翻译： 其中Ar为任选取代的芳基，R 1为氢或烷基，R 2为氢，烷基，链烯基，炔基，任选取代的芳烷基或任选取代的环烷基烷基，X为氮原子的杀真菌活性的新型羟乙唑基肟衍生物 原子或CH基团，以及其与酸和金属盐的加成产物。

公开(公告)号：US4618619A

公开(公告)日：1986-10-21

申请号：US589613

申请日：1984-03-14

申请人： Erik Regel ,  Karl H. Buchel ,  Paul Reinecke ,  Wilhelm Brandes

发明人： Erik Regel ,  Karl H. Buchel ,  Paul Reinecke ,  Wilhelm Brandes

IPC分类号： A01N31/14 ,  A01N31/00 ,  A01N31/02 ,  A01N33/04 ,  A01N33/08 ,  A01N43/48 ,  A01N43/50 ,  A01N43/56 ,  A01N43/64 ,  A01N43/653 ,  C07D249/08 ,  C07D303/22 ,  C07D303/24 ,  C07D303/34 ,  C07D303/36 ,  C07D521/00

CPC分类号： C07D303/22 ,  A01N43/50 ,  A01N43/56 ,  A01N43/653 ,  C07C323/00 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D303/24 ,  C07D303/34 ,  C07D303/36

摘要： A method of combating plant pathogenic fungi which comprises administering to such fungi or to a habitat thereof a plant pathogenic fungicidally effective amount of a substituted tert.-butanol derivative of the formula ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 are identical or different and represent azolyl, optionally substituted phenoxy, optionally substituted phenylthio, alkylthio, alkenyl, alkinyl, optionally substituted phenylacetylenyl, alkylamino, dialkylamino, optionally substituted phenylamino, optionally substituted phenyl-N-alkyl-amino, optionally substituted cycloalkylamino, optionally substituted cycloalkyl-N-alkyl-amino, aminoethoxy, alkylaminoethoxy or dialkylaminoethyoxy,or an acid addition salt or metal salt complex thereof.

摘要翻译： 一种防治植物致病真菌的方法，其包括向所述真菌或其栖息地施用植物病原真菌有效量的式（I）的取代的叔丁醇衍生物，其中R 1，R 2和R 3相同 任选取代的苯基乙酰基，烷基氨基，二烷基氨基，任选取代的苯基氨基，任选取代的苯基-N-烷基 - 氨基，任选取代的环烷基氨基，任选取代的环烷基 - N-烷基 - 氨基，氨基乙氧基，烷基氨基乙氧基或二烷基氨基乙氧基，或其酸加成盐或金属盐络合物。