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51.发明申请System and Methods for Performing Neurophysiologic Assessments During Spine Surgery 审中-公开脊柱外科神经生理评估系统与方法公开(公告)号：US20090177112A1
公开(公告)日：2009-07-09
申请号：US11883709
申请日：2006-02-02
Applicant: James Gharib , Allen Farquhar , Doug Layman , Jeff Balzer , Blair Calancie
Inventor： James Gharib , Allen Farquhar , Doug Layman , Jeff Balzer , Blair Calancie
IPC: A61B5/05
CPC classification number: A61B5/0488 , A61B5/4041 , A61B5/407 , A61B5/4504 , A61B5/4893 , A61B5/7475 , A61N1/0548 , A61N1/36003 , A61N1/36014 , A61N1/37247
Abstract: The present invention relates generally to an algorithm aimed at neurophysiology monitoring, and more particularly to an algorithm capable of quickly finding stimulation thresholds over multiple channels of a neurophysiology monitoring system.
Abstract translation: 本发明一般涉及一种旨在进行神经生理学监测的算法，更具体地说，涉及一种能够在神经生理学监测系统的多个通道上快速找到刺激阈值的算法。
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52.发明申请System and Methods for Performing Pedicle Integrity Assessments of the Thoracic Spine 有权执行胸椎椎弓根完整性评估的系统和方法公开(公告)号：US20080221473A1
公开(公告)日：2008-09-11
申请号：US11994411
申请日：2006-09-22
Applicant: Blair Calancie , James Gharib , Allen Farquhar , Doug Layman
Inventor： Blair Calancie , James Gharib , Allen Farquhar , Doug Layman
CPC classification number: A61B5/0488 , A61B5/4041 , A61B5/407 , A61B5/4893 , A61N1/36003 , A61N1/36014 , A61N1/37247
Abstract: The present invention includes a system and methods aimed at surgery, and more particularly to a system and methods for monitoring nervous tissue to assess the integrity of a pedicle wall during or after pilot hole formation and before, during, or after screw implantation, particularly in the thoracic spine. The system also performs other neurophysiologic assessments including, but not necessarily limited to, neuromuscular pathway status, nerve proximity detection, nerve pathology monitoring, and spinal cord health monitoring.
Abstract translation: 本发明包括一种旨在手术的系统和方法，更具体地说，涉及用于监测神经组织的系统和方法，以在螺钉植入之前，之中或之后评估椎弓根壁的完整性，特别是在 胸椎。 该系统还执行其他神经生理学评估，包括但不一定限于神经肌肉通路状态，神经接近检测，神经病理学监测和脊髓健康监测。
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公开(公告)号：US20050075578A1
公开(公告)日：2005-04-07
申请号：US10809280
申请日：2004-03-25
Applicant: James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros , Eric Finley , Jamil Elbanna , Scot Martinelli
Inventor： James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey Blewett , Goretti Medeiros , Eric Finley , Jamil Elbanna , Scot Martinelli
IPC: A61B5/0488 , A61B20060101 , A61B1/00 , A61B5/04 , A61B5/0492 , A61B17/34 , A61B19/00 , A61B5/05
CPC classification number: A61F2/4611 , A61B1/32 , A61B5/04001 , A61B5/0492 , A61B5/4893 , A61B5/6828 , A61B5/6831 , A61B17/0218 , A61B17/3417 , A61B17/3421 , A61B17/3423 , A61B34/20 , A61B34/25 , A61B90/36 , A61B90/37 , A61B2017/00039 , A61B2017/00199 , A61B2017/0262 , A61B2034/2053 , A61B2034/2072 , A61F2/4455 , A61F2002/4635 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36135 , A61N1/36142 , A61N1/36157 , A61N1/37247
Abstract: The present invention involves systems and related methods for performing surgical procedures and assessments, including the use of neurophysiology-based monitoring to: (a) determine nerve proximity and nerve direction to surgical instruments employed in accessing a surgical target site; (b) assess the pathology (health or status) of a nerve or nerve root before, during, or after a surgical procedure; and/or (c) assess pedicle integrity before, during or after pedicle screw placement, all in an automated, easy to use, and easy to interpret fashion so as to provide a surgeon-driven system.
Abstract translation: 本发明涉及用于执行外科手术和评估的系统和相关方法，包括使用基于神经生理学的监测来：（a）确定在进入手术靶位点时使用的手术器械的神经接近度和神经方向; （b）在外科手术之前，期间或之后评估神经或神经根的病理（健康或状况）; 和/或（c）在椎弓根螺钉放置之前，之中或之后评估椎弓根完整性，全部以自动化，易于使用和易于解释的方式，以提供外科医生驱动的系统。
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54.发明授权公开(公告)号：US08812116B2
公开(公告)日：2014-08-19
申请号：US13465666
申请日：2012-05-07
Applicant: Norbert F. Kaula , James Gharib , Allen Farquhar , Goretti Medeiros
Inventor： Norbert F. Kaula , Jeffrey J. Blewett , James Gharib , Allen Farquhar
CPC classification number: A61B5/4893 , A61B5/04001 , A61B5/0488 , A61B5/1106 , A61B5/4836 , A61B5/7217 , A61B5/743 , A61B17/00 , A61B17/02 , A61B2017/00039 , A61N1/08 , A61N1/36 , A61N1/36017
Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.
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55.发明授权System and methods for performing neurophysiologic assessments with pressure monitoring 有权用压力监测进行神经生理学评估的系统和方法公开(公告)号：US08740783B2
公开(公告)日：2014-06-03
申请号：US11490717
申请日：2006-07-20
Applicant: James Gharib , Allen Farquhar , Scot Martinelli , David Ivanko , Benjamin VerHage
Inventor： James Gharib , Allen Farquhar , Scot Martinelli , David Ivanko , Benjamin VerHage
IPC: A61B1/32
CPC classification number: A61B5/04001 , A61B5/0488 , A61B5/05 , A61B5/4029 , A61B5/4893
Abstract: Systems and methods for performing neurophysiologic assessments of neural tissue including nerve pathology monitoring which may or may not be augmented by adding the ability to assess or monitor the pressure being exerted upon a nerve or nerve root before, during and/or after retraction.
Abstract translation: 用于进行神经组织的神经生理学评估的系统和方法，包括神经病理学监测，其可以或可以不通过增加评估或监测在收缩之前，期间和/或之后施加在神经或神经根上的压力的能力来增强。
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Patent Agency Ranking
56.发明授权公开(公告)号：US08591431B2
公开(公告)日：2013-11-26
申请号：US11994411
申请日：2006-09-22
Applicant: Blair Calancie , James Gharib , Allen Farquhar , Doug Layman
Inventor： Blair Calancie , James Gharib , Allen Farquhar , Doug Layman
IPC: A61B5/053
CPC classification number: A61B5/0488 , A61B5/4041 , A61B5/407 , A61B5/4893 , A61N1/36003 , A61N1/36014 , A61N1/37247
Abstract: The present invention includes a system and methods aimed at surgery, and more particularly to a system and methods for monitoring nervous tissue to assess the integrity of a pedicle wall during or after pilot hole formation and before, during, or after screw implantation, particularly in the thoracic spine. The system also performs other neurophysiologic assessments including, but not necessarily limited to, neuromuscular pathway status, nerve proximity detection, nerve pathology monitoring, and spinal cord health monitoring.
Abstract translation: 本发明包括一种旨在手术的系统和方法，更具体地说，涉及用于监测神经组织的系统和方法，以在螺钉植入之前，之中或之后评估椎弓根壁的完整性，特别是在 胸椎。 该系统还执行其他神经生理学评估，包括但不一定限于神经肌肉通路状态，神经接近检测，神经病理学监测和脊髓健康监测。
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公开(公告)号：US08303498B2
公开(公告)日：2012-11-06
申请号：US13030798
申请日：2011-02-18
Applicant: Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert F. Kaula , Jeffrey J. Blewett , Goretti Medeiros, legal representative
Inventor： Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert F. Kaula , Jeffrey J. Blewett
IPC: A61B1/32
CPC classification number: A61B17/0206 , A61B1/32 , A61B5/04001 , A61B5/4836 , A61B17/02 , A61B17/0218 , A61B2017/0256
Abstract: A surgical access system including a tissue distraction assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
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公开(公告)号：US20120226106A1
公开(公告)日：2012-09-06
申请号：US13466531
申请日：2012-05-08
Applicant: Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey J. Blewett , Goretti Medeiros
Inventor： Patrick Miles , Scot Martinelli , Eric Finley , James Gharib , Allen Farquhar , Norbert Kaula , Jeffrey J. Blewett , Goretti Medeiros
IPC: A61B1/32
CPC classification number: A61B17/025 , A61B1/32 , A61B5/4893 , A61B17/0206 , A61B17/0218 , A61B2017/00473 , A61B2017/0262
Abstract: A surgical access system including a tissue distraction assembly and a tissue refraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
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59.发明申请System and Methods for Determining Nerve Proximity, Direction, and Pathology During Surgery 有权用于确定手术中神经靠近，方向和病理学的系统和方法公开(公告)号：US20120220891A1
公开(公告)日：2012-08-30
申请号：US13465666
申请日：2012-05-07
Applicant: Norbert F. Kaula , Jeffrey J. Blewett , James Gharib , Allen Farquhar , Goretti Medeiros
Inventor： Norbert F. Kaula , Jeffrey J. Blewett , James Gharib , Allen Farquhar , Goretti Medeiros
IPC: A61B5/053 , A61B5/0488 , A61M29/00
CPC classification number: A61B5/4893 , A61B5/04001 , A61B5/0488 , A61B5/1106 , A61B5/4836 , A61B5/7217 , A61B5/743 , A61B17/00 , A61B17/02 , A61B2017/00039 , A61N1/08 , A61N1/36 , A61N1/36017
Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.
Abstract translation: 本发明涉及用于基于神经肌肉反应和引起神经肌肉反应的刺激信号之间确定的关系来确定相对于外科器械的神经接近度，神经方向和病理学的系统和方法。
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公开(公告)号：US08244343B2
公开(公告)日：2012-08-14
申请号：US13215791
申请日：2011-08-23
Applicant: James Gharib , Allen Farquhar , Norbert F. Kaula , Jeffrey J. Blewett , Goretti Medeiros, legal representative , Eric Finley , Scot Martinelli
Inventor： James Gharib , Allen Farquhar , Norbert F. Kaula , Jeffrey J. Blewett , Eric Finley , Scot Martinelli
IPC: A61B5/04
CPC classification number: A61F2/4611 , A61B1/32 , A61B5/04001 , A61B5/0492 , A61B5/4893 , A61B5/6828 , A61B5/6831 , A61B17/0218 , A61B17/3417 , A61B17/3421 , A61B17/3423 , A61B34/20 , A61B34/25 , A61B90/36 , A61B90/37 , A61B2017/00039 , A61B2017/00199 , A61B2017/0262 , A61B2034/2053 , A61B2034/2072 , A61F2/4455 , A61F2002/4635 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36135 , A61N1/36142 , A61N1/36157 , A61N1/37247
Abstract: The present invention involves systems and related methods for performing surgical procedures and assessments, including the use of neurophysiology-based monitoring to: (a) determine nerve proximity and nerve direction to surgical instruments employed in accessing a surgical target site; (b) assess the pathology (health or status) of a nerve or nerve root before, during, or after a surgical procedure; and/or (c) assess pedicle integrity before, during or after pedicle screw placement, all in an automated, easy to use, and easy to interpret fashion so as to provide a surgeon-driven system.
Abstract translation: 本发明涉及用于执行外科手术和评估的系统和相关方法，包括使用基于神经生理学的监测来：（a）确定在进入手术靶位点时使用的手术器械的神经接近度和神经方向; （b）在外科手术之前，期间或之后评估神经或神经根的病理（健康或状况）; 和/或（c）在椎弓根螺钉放置之前，之中或之后评估椎弓根完整性，全部以自动化，易于使用和易于解释的方式，以提供外科医生驱动的系统。
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