公开(公告)号：US07809103B2

公开(公告)日：2010-10-05

申请号：US11756027

申请日：2007-05-31

申请人： Yanfeng Du ,  Forrest Frank Hopkins ,  Joseph Bendahan

发明人： Yanfeng Du ,  Forrest Frank Hopkins ,  Joseph Bendahan

IPC分类号： G01N23/087

CPC分类号： G01N23/09

摘要： Disclosed herein is a method for detecting high atomic number elements in an article by using radiation having two different energies. The detecting of high atomic number elements can be accomplished by using an algorithm, curve fitting or using a data table. Disclosed herein too is a radiation system that uses the aforementioned method for detecting high atomic number elements.

摘要翻译： 本文公开了一种通过使用具有两种不同能量的辐射来检测物品中的高原子数元素的方法。 高原子数元素的检测可以通过使用算法，曲线拟合或使用数据表来完成。 这里也公开了使用上述检测高原子数元素的方法的辐射系统。

公开(公告)号：US07634060B2

公开(公告)日：2009-12-15

申请号：US11745856

申请日：2007-05-08

申请人： David M. Hoffman ,  James W. LeBlanc ,  John Eric Tkaczyk ,  Robert F. Senzig ,  Yanfeng Du

发明人： David M. Hoffman ,  James W. LeBlanc ,  John Eric Tkaczyk ,  Robert F. Senzig ,  Yanfeng Du

IPC分类号： G01T1/24

CPC分类号： G01T1/2928 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/5205

摘要： A CT detector capable of energy discrimination and direct conversion is disclosed. The detector includes multiple layers of semiconductor material with the layers having varying thicknesses. The detector is constructed to be segmented in the x-ray penetration direction so as to optimize count rate performance as well as avoid saturation. The detector also includes variable pixel pitch and a flexible binning of pixels to further enhance count rate performance.

公开(公告)号：US07570736B2

公开(公告)日：2009-08-04

申请号：US11768775

申请日：2007-06-26

申请人： David M. Hoffman ,  James W. LeBlanc ,  John Eric Tkaczyk ,  Robert F. Senzig ,  Yanfeng Du

发明人： David M. Hoffman ,  James W. LeBlanc ,  John Eric Tkaczyk ,  Robert F. Senzig ,  Yanfeng Du

IPC分类号： A61B6/03

CPC分类号： G01T1/2928 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/5205

摘要： A CT detector capable of energy discrimination and direct conversion is disclosed. The detector includes multiple layers of semiconductor material with the layers having varying thicknesses. The detector is constructed to be segmented in the x-ray penetration direction so as to optimize count rate performance as well as avoid saturation. The detector also includes variable pixel pitch and a flexible binning of pixels to further enhance count rate performance.

摘要翻译： 公开了能够鉴别和直接转换的CT检测器。 检测器包括多层半导体材料，其中层具有变化的厚度。 检测器被构造成在x射线穿透方向上分段，以便优化计数率性能以及避免饱和。 检测器还包括可变像素间距和灵活的像素分组，以进一步提高计数率性能。

公开(公告)号：US20090132789A1

公开(公告)日：2009-05-21

申请号：US12199039

申请日：2008-08-27

申请人： Naresh Kesavan Rao ,  Brian David Yanoff ,  Yanfeng Du ,  Jianjun Guo

发明人： Naresh Kesavan Rao ,  Brian David Yanoff ,  Yanfeng Du ,  Jianjun Guo

IPC分类号： G06F15/76

CPC分类号： G06G7/18 ,  A61B6/037

摘要： An application-specific integrated circuit (ASIC) comprising a plurality of channels, each channel having circuitry for time and energy discrimination, a plurality of programmable registers, each programmable register configured to output at least one configuration parameter for the circuitry, and a channel-select register configured to identify a channel of the plurality of channels to be configured. The ASIC further includes a configuration-select register configured to identify the programmable register to be used for channel configuration, and a communications interface configured to transmit instructions received from a controller to one of the channel-select register, the configuration-select register, and the plurality of programmable registers.

摘要翻译： 一种专用集成电路（ASIC），包括多个通道，每个通道具有用于时间和能量鉴别的电路，多个可编程寄存器，每个可编程寄存器被配置为输出用于该电路的至少一个配置参数， 选择寄存器，其被配置为识别要配置的多个信道的信道。 ASIC还包括配置选择寄存器，配置为识别要用于信道配置的可编程寄存器，以及通信接口，被配置为将从控制器接收的指令发送到频道选择寄存器，配置选择寄存器和 多个可编程寄存器。

公开(公告)号：US20090129537A1

公开(公告)日：2009-05-21

申请号：US12198989

申请日：2008-08-27

申请人： Naresh Kesavan Rao ,  Brian David Yanoff ,  Yanfeng Du ,  Jianjun Guo

发明人： Naresh Kesavan Rao ,  Brian David Yanoff ,  Yanfeng Du ,  Jianjun Guo

IPC分类号： H05G1/60 ,  H03M1/12

CPC分类号： G06G7/18

摘要： A data acquisition system including a readout Application Specific Integrated Circuit (ASIC) having a plurality of channels, each channel having a time discriminating circuit and an energy discriminating circuit, wherein the ASIC is configured to receive a plurality of signals from a semiconductor radiation detector. The data acquisition system also includes a digital-to-analog converter (DAC) electrically coupled to the ASIC and configured to provide a reference signal to the ASIC used in the generation of digital outputs from the ASIC, and a controller electrically coupled to the ASIC and to the DAC, the controller configured to instruct the DAC to provide the reference signal to the ASIC.

摘要翻译： 一种数据采集系统，包括具有多个通道的读出专用集成电路（ASIC），每个通道具有时间鉴别电路和能量识别电路，其中ASIC被配置为从半导体辐射检测器接收多个信号。 数据采集​​系统还包括电耦合到ASIC的数模转换器（DAC），并被配置为向ASIC中产生数字输出使用的ASIC提供参考信号，以及电耦合到ASIC的控制器 并且所述控制器被配置为指示所述DAC向所述ASIC提供所述参考信号。

公开(公告)号：US20090052621A1

公开(公告)日：2009-02-26

申请号：US11843700

申请日：2007-08-23

申请人： Deborah Joy Walter ,  Xiaoye Wu ,  John Eric Tkaczyk ,  Yanfeng Du

发明人： Deborah Joy Walter ,  Xiaoye Wu ,  John Eric Tkaczyk ,  Yanfeng Du

IPC分类号： G01N23/06

CPC分类号： G01N23/087 ,  A61B5/4869 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/4042 ,  A61B6/405 ,  A61B6/4241 ,  A61B6/482 ,  G01N2223/423 ,  G01N2223/424

摘要： A diagnostic imaging system includes a high frequency electromagnetic energy source that emits a beam of high frequency electromagnetic energy toward an object to be imaged, a detector that receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source, and a data acquisition system (DAS) operably connected to the detector. A computer is operably connected to the DAS and is programmed to generate corresponding sets of projection values for three or more energy spectra through employment of attenuation coefficients of three or more basis materials to simulate responses of the diagnostic imaging system to a plurality of lengths of the three or more basis materials wherein the three or more basis materials comprise two or more non K-edge basis materials and one or more K-edge basis materials.

摘要翻译： 一种诊断成像系统包括：高频电磁能源，其向待成像对象发射高频电磁能束;接收由高频电磁能源发出的高频电磁能的检测器;以及数据采集系统（ DAS）可操作地连接到检测器。 计算机可操作地连接到DAS，并被编程为通过使用三个或更多个基础材料的衰减系数来产生三个或更多个能量谱的相应的投影值组，以模拟诊断成像系统对多个长度的 三种或更多种基础材料，其中三种或更多种基材包含两种或多种非K边缘基础材料和一种或多种K边缘基础材料。

公开(公告)号：US20080135789A1

公开(公告)日：2008-06-12

申请号：US11609262

申请日：2006-12-11

申请人： Yanfeng Du ,  John Eric Tkaczyk

发明人： Yanfeng Du ,  John Eric Tkaczyk

IPC分类号： G01N23/04

CPC分类号： A61B6/4241 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/482 ,  A61B6/583

摘要： A diagnostic imaging system in an example comprises a high frequency electromagnetic energy source, a detector, a data acquisition system (DAS), and a computer. The high frequency electromagnetic energy source emits a beam of high frequency electromagnetic energy toward an object to be imaged. The detector receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source. The DAS is operably connected to the detector. The computer is operably connected to the DAS and programmed to employ a threshold to trigger a filter operation on a pixel, in a basis material decomposition (BMD) image of a plurality of BMD images, through comparison of an actual noise ratio between a pair of BMD images, of the plurality of BMD images, to a theoretical BMD noise ratio value. The computer operably connected to the DAS is programmed to employ a correlation in noise distribution of the plurality of BMD images to reduce image noise in the plurality of BMD images. The computer operably connected to the DAS is programmed to realize an adaptive algorithm through employment of an exponential correction function of a difference between the actual noise ratio and the theoretical BMD noise ratio value. The computer operably connected to the DAS is programmed to employ the adaptive algorithm to reduce the image noise in the plurality of BMD images.

摘要翻译： 示例中的诊断成像系统包括高频电磁能源，检测器，数据采集系统（DAS）和计算机。 高频电磁能源朝向要成像的物体发射高频电磁能束。 检测器接收高频电磁能源发出的高频电磁能。 DAS可操作地连接到检测器。 计算机可操作地连接到DAS，并且被编程为通过比较多个BMD图像中的实际噪声比，在多个BMD图像的基础材料分解（BMD）图像中采用阈值来触发像素上的滤波器操作 多个BMD图像中的BMD图像达到理论BMD噪声比值。 可操作地连接到DAS的计算机被编程为在多个BMD图像的噪声分布中采用相关性，以减少多个BMD图像中的图像噪声。 可操作地连接到DAS的计算机被编程为通过使用实际噪声比和理论BMD噪声比值之间的差的指数校正函数来实现自适应算法。 可操作地连接到DAS的计算机被编程为采用自适应算法来减少多个BMD图像中的图像噪声。

公开(公告)号：US07308073B2

公开(公告)日：2007-12-11

申请号：US11163496

申请日：2005-10-20

申请人： J. Eric Tkaczyk ,  Deborah J. Walter ,  Xiaoye Wu ,  Brian C. Bales ,  James W. Leblanc ,  Yanfeng Du

发明人： J. Eric Tkaczyk ,  Deborah J. Walter ,  Xiaoye Wu ,  Brian C. Bales ,  James W. Leblanc ,  Yanfeng Du

IPC分类号： G21K3/00

CPC分类号： G21K1/10

摘要： A bowtie filter is constructed to have a fluidic envelope filled with attenuating fluid and a displacement insert that can present various x-ray attenuation profiles during a scan. The insert is designed to displace the attenuating fluid to achieve a denied attenuating or filtering profile. The insert can be rotated, twisted, moved, and otherwise contorted within the fluidic envelope as needed during the course of a scan. As the angle, position and shape of the zombie is changed, the x-ray profile of the filter changes. The insert may have a default shape when at rest, but can have its shape changed when external forces are placed thereon. As x-ray filtering needs change during the course of the scan, the insert can be compressed, stretched, and/or contorted to achieve additional filtering profiles.

摘要翻译： 弓形过滤器被构造成具有填充有衰减流体的流体信封和可在扫描期间呈现各种x射线衰减分布的位移插入件。 插入件被设计成使衰减流体移位以实现被拒绝的衰减或过滤轮廓。 在扫描过程中，插入物可以根据需要旋转，扭转，移动，并且在流体封套内扭曲。 随着僵尸的角度，位置和形状的改变，过滤器的X射线轮廓也会改变。 当静止时，插入件可以具有默认形状，但是当外力在其上放置时，其形状可以改变。 由于X射线过滤在扫描过程中需要更改，所以插入物可以被压缩，拉伸和/或扭转以实现额外的过滤轮廓。

公开(公告)号：US07260172B2

公开(公告)日：2007-08-21

申请号：US11627072

申请日：2007-01-25

申请人： Jerome Stephen Arenson ,  Evgeny Drapkin ,  Yanfeng Du ,  Lev Greenberg ,  Oded Meirav ,  David Ruimi ,  John Eric Tkaczyk ,  Xiaoye Wu

发明人： Jerome Stephen Arenson ,  Evgeny Drapkin ,  Yanfeng Du ,  Lev Greenberg ,  Oded Meirav ,  David Ruimi ,  John Eric Tkaczyk ,  Xiaoye Wu

IPC分类号： G01N23/083

CPC分类号： G01T1/1644 ,  A61B6/027 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/482 ,  A61B6/583 ,  G01T1/1647 ,  G06T5/002 ,  G06T5/20 ,  G06T2207/10081 ,  G06T2207/30004 ,  G06T2207/30112 ,  Y10S378/901

摘要： An adaptive CT data acquisition system and technique is presented whereby radiation emitted for CT data acquisition is dynamically controlled to limit exposure to those detectors of a CT detector assembly that may be particularly susceptible to saturation during a given data acquisition. The data acquisition technique recognizes that for a given subject size and position that pre-subject filtering and collimating of a radiation beam may be insufficient to completely prevent detector saturation. Therefore, the present invention includes implementation of a number of CT data correction techniques for correcting otherwise unusable data of a saturated CT detector. These data correction techniques include a nearest neighbor correction, off-centered phantom correction, off-centered synthetic data correction, scout data correction, planar radiogram correction, and a number of others. The invention is applicable with energy discriminating CT systems as well as with conventional CT systems and other multi-energy CT systems, such as dual kVp-based systems.

摘要翻译： 提出了一种自适应CT数据采集系统和技术，其中动态地控制用于CT数据采集的辐射，以限制在给定数据采集期间可能特别容易饱和的CT检测器组件的那些检测器的暴露。 数据采集​​技术认识到，对于给定的主体大小和位置，预辐射滤波和辐射束的准直可能不足以完全防止检测器饱和。 因此，本发明包括实现用于校正饱和CT检测器的其他不可用数据的多个CT数据校正技术。 这些数据校正技术包括最近邻校正，偏心幻像校正，偏心合成数据校正，侦察数据校正，平面放射线图校正以及其他数目。 本发明适用于能量识别CT系统以及常规CT系统和其他多能CT系统，例如基于双kVp的系统。

公开(公告)号：US07065234B2

公开(公告)日：2006-06-20

申请号：US10784099

申请日：2004-02-23

申请人： Yanfeng Du ,  Forrest Frank Hopkins

发明人： Yanfeng Du ,  Forrest Frank Hopkins

IPC分类号： G06K9/00

CPC分类号： G06T11/005 ,  A61B6/5282

摘要： A method of correcting scatter includes obtaining a voxellized representation of a 3D image of an object from a plurality of projection data. A single scatter profile for the object is calculated using the voxellized representation of the 3D image of the object. A total scatter profile for the object is determined using the single scatter profile and an adjustment factor and the projection data is corrected using the total scatter profile to obtain a scatter corrected projection data. A beam hardening correction method includes simulating a number of attenuation data for an x-ray spectrum, at least one object material, and a detector spectral response. A function is fitted to the attenuation data to obtain an attenuation curve. A number of projection data for an object are corrected using the attenuation curve to obtain a number of beam hardening corrected projection data. A corrected image of the object is reconstructed from the beam hardening corrected image data.

摘要翻译： 校正散射的方法包括从多个投影数据获得对象的3D图像的体素化表示。 使用对象的3D图像的体素化表示来计算对象的单个散点图。 使用单个散射曲线和调整因子确定对象的总散射曲线，并且使用总散射曲线校正投影数据以获得散射校正的投影数据。 光束硬化校正方法包括模拟用于X射线光谱，至少一种物体材料和检测器光谱响应的多个衰减数据。 对衰减数据拟合一个函数以获得衰减曲线。 使用衰减曲线来校正用于对象的多个投影数据，以获得多个光束硬化校正投影数据。 从光束硬化校正图像数据重建对象的校正图像。