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公开(公告)号：US10689666B2
公开(公告)日：2020-06-23
申请号：US16572998
申请日：2019-09-17
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine Chay , Artem Evdokimov , Stanislaw Flasinski , Uma R. Kesanapalli , Megan N. Schroder , Rachael N. Slightom , Nengbing Tao , Andrew M. Wollacott
Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
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公开(公告)号：US20200002719A1
公开(公告)日：2020-01-02
申请号：US16573538
申请日：2019-09-17
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
IPC: C12N15/82 , C07K14/325 , A01N47/08 , A01N63/02
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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公开(公告)号：US20190292542A1
公开(公告)日：2019-09-26
申请号：US16374211
申请日：2019-04-03
Applicant: Monsanto Technology LLC
Inventor： Stanislaw Flasinski , Charles R. Dietrich , Wei Wu , Zhaolong Li , Bo-Xing Qiu , Liang Guo , Jaishree M. Chittoor
IPC: C12N15/113 , C12N15/82
Abstract: The invention provides DNA molecules and constructs, and their nucleotide sequences, useful for modulating gene expression in plants, and for specifying intracellular or extracellular localization of a gene product of interest. Transgenic plants, plant cells, plant parts, and seeds, comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided.
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公开(公告)号：US10316330B2
公开(公告)日：2019-06-11
申请号：US15222789
申请日：2016-07-28
Applicant: Monsanto Technology LLC
Inventor： Wen C. Burns , Catherine A. Chay , Cheryl L. Cloninger , Mingqi Deng , Stanislaw Flasinski , Kunsheng Wu
IPC: C12N15/82
Abstract: The invention provides corn event MON 87411, and plants, plant cells, seeds, plant parts, and commodity products comprising event MON 87411. The invention also provides polynucleotides specific for event MON 87411 and plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides specific for event MON 87411. The invention also provides methods related to event MON 87411.
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公开(公告)号：US20180346925A1
公开(公告)日：2018-12-06
申请号：US16002994
申请日：2018-06-07
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Stanislaw Flasinski , Yong Yin
CPC classification number: C12N15/8286 , A01N37/46 , A01N63/02 , C07K14/325 , C12Q1/6897 , Y02A40/162
Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran, Lepidopteran, and Hemipteran pest species is disclosed, and includes, but is not limited to, TIC5290. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC5290 pesticidal protein. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC5290 pesticidal protein of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, and Hemipteran species pests using the TIC5290 pesticidal protein are also provided.
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Patent Agency Ranking
公开(公告)号：US20180334684A1
公开(公告)日：2018-11-22
申请号：US16047187
申请日：2018-07-27
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
IPC: C12N15/82 , A01N63/02 , C07K14/325 , A01N47/08
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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公开(公告)号：US10100330B2
公开(公告)日：2018-10-16
申请号：US15221544
申请日：2016-07-27
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Stanislaw Flasinski , Yong Yin
IPC: C12N15/82 , C07K14/325 , A01N37/46 , A01N63/02 , C12Q1/6897
Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran, Lepidopteran, and Hemipteran pest species is disclosed, and includes, but is not limited to, TIC5290. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC5290 pesticidal protein. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC5290 pesticidal protein of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, and Hemipteran species pests using the TIC5290 pesticidal protein are also provided.
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公开(公告)号：US10059959B2
公开(公告)日：2018-08-28
申请号：US14884432
申请日：2015-10-15
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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公开(公告)号：US20180208940A1
公开(公告)日：2018-07-26
申请号：US15846796
申请日：2017-12-19
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Jason S. Milligan , James K. Roberts , Yong Yin
IPC: C12N15/82 , C12N15/74 , C07K14/435
Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.
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公开(公告)号：US20180127774A1
公开(公告)日：2018-05-10
申请号：US15849012
申请日：2017-12-20
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC: C12N15/82
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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