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247 条记录 (耗时 0.044 秒)

    Method for continuous catalytic hydrogenation
    51.
    发明授权
    Method for continuous catalytic hydrogenation 有权
    连续催化氢化方法

    公开(公告)号：US08586784B2

    公开(公告)日：2013-11-19

    申请号：US11320409

    申请日：2005-12-29

    申请人： Michael Grass ,  Burkhard Reeken ,  Axel Tuchlenski ,  Alfred Kaizik

    发明人： Michael Grass ,  Burkhard Reeken ,  Axel Tuchlenski ,  Alfred Kaizik

    IPC分类号： C07C61/00

    CPC分类号： C07C67/303 ,  Y02P20/582 ,  C07C69/75

    摘要： The invention relates to the preparation of alicyclic carboxylic acids or their derivatives by selective hydrogenation of the corresponding aromatic carboxylic acid (derivatives) in at least two series-connected reactors, at least one reactor being operated in loop operating mode. The catalyst volumes in the method are set in such a manner that the catalyst volume required, based on the conversion rate, is as low as possible.

    摘要翻译： 本发明涉及通过在至少两个串联连接的反应器中选择性氢化相应的芳族羧酸（衍生物）来制备脂环族羧酸或其衍生物，至少一个反应器以循环操作模式操作。 该方法中的催化剂体积设定为使得基于转化率所需的催化剂体积尽可能低。

    COMPUTED TOMOGRAPHY SYSTEM AND METHOD FOR TRACKING A BOLUS
    52.
    发明申请
    COMPUTED TOMOGRAPHY SYSTEM AND METHOD FOR TRACKING A BOLUS 有权
    计算机图像系统和追踪玻璃的方法

    公开(公告)号：US20130279783A1

    公开(公告)日：2013-10-24

    申请号：US13977042

    申请日：2012-01-04

    申请人： Holger Schmitt ,  Michael Grass

    发明人： Holger Schmitt ,  Michael Grass

    IPC分类号： G06T11/00

    CPC分类号： G06T11/008 ,  A61B6/032 ,  A61B6/469 ,  A61B6/481 ,  A61B6/488 ,  A61B6/504

    摘要： The present invention relates to a computed tomography system (10) and a corresponding method which enable tracking of a contrast material bolus and which involve a reduced radiation dose. The proposed computed tomography system (10) comprises an acquisition unit including an X-ray source (18) and an X-ray detector (30) for acquiring projection data sets (42, 44, 46), a reconstruction unit (41) for reconstructing a planning image (48) from a first projection data set (42), an identification unit (52) for identifying a region of interest (40) in the planning image (48), a selection unit (54) for selecting a projection angle (60) through the region of interest (40), a calculator (62) for calculating a target projection value (64) for a projection of said region of interest (40) with the selected projection angle (60), a control unit (32) for controlling said acquisition unit to acquire a second, reduced projection data set (44) including projection data from projections of said region of interest (40) with the selected projection angle (60), and a comparator (68) for comparing projection values of the second projection data set (44) with the target projection value (64), wherein the control unit (32) is adapted to control the acquisition unit to initiate the acquisition of a third projection data set (46) based on the comparison result (70) and to reconstruct a diagnostic image (50) from the third projection data set (46).

    摘要翻译： 本发明涉及计算机断层摄影系统（10）和相应的方法，其能够跟踪造影剂推注并涉及降低的辐射剂量。 所提出的计算机断层摄影系统（10）包括：采集单元，包括用于获取投影数据组（42,44,46）的X射线源（18）和X射线检测器（30）;重建单元（41），用于 从第一投影数据集（42）重建规划图像（48）;识别单元（52），用于识别所述规划图像（48）中的感兴趣区域（40）;选择单元（54），用于选择投影 通过感兴趣区域（40）的角度（60）;计算器（62），用于计算用于所选择的投影角度（60）的所述感兴趣区域（40）的投影的目标投影值（64）;控制单元 （32），用于控制所述获取单元以选择的投影角度（60）获取包括来自所述感兴趣区域（40）的投影的投影数据的第二缩小投影数据集（44），以及比较器 第二投影数据集（44）的投影值与目标投影值（64），w 这里，控制单元（32）适于控制采集单元基于比较结果（70）开始获取第三投影数据集（46），并且从第三投影数据集重建诊断图像（50） （46）。

    Apparatus for generating an image of moving object
    54.
    发明授权
    Apparatus for generating an image of moving object 有权
    用于产生移动物体的图像的装置

    公开(公告)号：US08478014B2

    公开(公告)日：2013-07-02

    申请号：US12990817

    申请日：2009-05-05

    申请人： Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

    发明人： Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

    IPC分类号： G06K9/00

    CPC分类号： G06T11/005 ,  G06T7/564 ,  G06T2211/412

    摘要： The present invention relates to an apparatus for generating an image of a moving object, wherein a movement of the object comprises a multiple of moving phases. The apparatus comprises a measured detection data providing unit (20) for providing measured detection data of the moving object, which have been detected by using a detection process and which are assigned to the moving phases. The apparatus comprises further a reconstruction unit (13) for reconstructing an image object of the object from the provided measured detection data and an adaptation unit (18) for adapting the image object for different moving phases such that simulated detection data are adapted to the measured detection data of the respective moving phase, wherein the simulated detection data are determined by simulating the detection process, which has been used for detecting the measured detection data assigned to the respective moving phase, with the image object.

    摘要翻译： 本发明涉及一种用于生成移动物体的图像的装置，其中物体的移动包括多个移动相位。 该装置包括测量检测数据提供单元（20），用于提供已经通过使用检测处理检测并被分配给运动相位的移动物体的测量检测数据。 所述设备还包括用于根据所提供的测量的检测数据重建对象的图像对象的重建单元（13）和用于使图像对象适应不同的移动阶段的适配单元（18），使得模拟的检测数据适应于所测量的 检测数据，其中通过模拟已经用于检测分配给各个运动相位的测量检测数据的检测过程与图像对象来确定模拟检测数据。

    3D-ORIGINATED CARDIAC ROADMAPPING
    55.
    发明申请
    3D-ORIGINATED CARDIAC ROADMAPPING 有权
    3D原版CARDIAC ROADMAPPING

    公开(公告)号：US20130116551A1

    公开(公告)日：2013-05-09

    申请号：US13810292

    申请日：2011-07-15

    申请人： Raoul Florent ,  Vincent Auvray ,  Michael Grass ,  Dirk Schaefer ,  Gert Schoonenberg

    发明人： Raoul Florent ,  Vincent Auvray ,  Michael Grass ,  Dirk Schaefer ,  Gert Schoonenberg

    IPC分类号： A61B6/02

    CPC分类号： A61B6/022 ,  A61B6/12 ,  A61B6/4441 ,  A61B6/463 ,  A61B6/487 ,  A61B6/504 ,  A61B6/5223 ,  A61B6/5235 ,  A61B2090/364 ,  A61B2090/367

    摘要： The present invention relates to 3D-originated cardiac roadmapping. In order to improve the accuracy of the information provided to the user as navigation information, without any additional burden to the patient such as additional X-ray dose, a method is described comprising the steps of a) providing 3D+t image data of a vascular structure of an object; b) acquiring two-dimensional image data of the object, which object comprises the vascular structure, the 2D image data comprising at least one 2D image; c) projecting the vascular structure, thereby generating a plurality of mask images on the basis of a 3D+t image data; d) registering the at least one 2D image with one of the plurality of the mask images, wherein the registration comprises finding the maximum of a similarity factor between the mask images and the at least one 2D image; e) generating a combination of the at least one 2D image and a projection of the vascular structure on the basis of the 3D+t image data according to the registration; and f) displaying the combination as a guiding vessel tree projection. Thus improved cardiac roadmapping in form of a topographical roadmapping is provided since the roadmapping is based on three-dimensional data.

    摘要翻译： 本发明涉及3D起源的心脏路线图。 为了提高作为导航信息提供给用户的信息的准确性，对病人没有任何额外的负担，例如额外的X射线剂量，描述了一种方法，其包括以下步骤：a）提供一个 物体的血管结构; b）获取所述对象的二维图像数据，所述对象包括所述血管结构，所述2D图像数据包括至少一个2D图像; c）投影血管结构，从而基于3D + t图像数据生成多个掩模图像; d）使用所述多个掩模图像之一登记所述至少一个2D图像，其中所述注册包括找到所述掩模图像与所述至少一个2D图像之间的相似性因子的最大值; e）根据所述注册，基于所述3D + t图像数据生成所述至少一个2D图像和所述血管结构的投影的组合; 以及f）将组合显示为引导血管树投影。 因此，由于路线图基于三维数据，所以提供了形成路面图的形式的改进的心脏路线图。

    Imaging system for imaging a region of interest in different phases
    56.
    发明授权
    Imaging system for imaging a region of interest in different phases 有权
    用于在不同阶段成像感兴趣区域的成像系统

    公开(公告)号：US08437524B2

    公开(公告)日：2013-05-07

    申请号：US12521899

    申请日：2008-01-02

    申请人： Claas Bontus ,  Michael Grass ,  Carsten Oliver Schirra ,  Udo Van Stevendaal ,  Guy Lavi

    发明人： Claas Bontus ,  Michael Grass ,  Carsten Oliver Schirra ,  Udo Van Stevendaal ,  Guy Lavi

    IPC分类号： G06K9/00

    CPC分类号： G06T7/20 ,  A61B5/0402 ,  A61B6/027 ,  A61B6/032 ,  A61B6/469 ,  A61B6/503 ,  A61B6/504 ,  A61B6/541

    摘要： The invention relates to an imaging system for imaging a region of interest comprising a moving object, which moves less in small motion phases than in large motion phases. Detection values are provided and a small motion determination unit (15) determines the motion of the object in the region of interest in the small motion phases from the 5 detection values. A large motion determination unit (16) determines the motion of the object in the large motion phases from the determined motion of the object in the small motion phases. A reconstruction unit (17) reconstructs an image of the region of interest from the detection values, wherein the reconstruction unit (17) is adapted for performing a motion compensation using the determined motions in the small and large motion phases.

    摘要翻译： 本发明涉及一种用于对感兴趣的区域成像的成像系统，该成像系统包括移动物体，该运动物体在小运动相位上比在大运动相位中运动较少。 提供检测值，并且小运动确定单元（15）从5个检测值确定在小运动相位中的感兴趣区域中的对象的运动。 大运动确定单元（16）根据所确定的小运动阶段中的物体的运动来确定物体在大运动相位中的运动。 重建单元（17）从检测值重建感兴趣区域的图像，其中重建单元（17）适于使用在小的和大的运动阶段中确定的运动来执行运动补偿。

    Mixture of diesters of dianhydrohexitol derivatives with carboxylic acids of the empirical formula C8H17COOH, process for preparing these diesters, and use of these mixtures
    57.
    发明授权
    Mixture of diesters of dianhydrohexitol derivatives with carboxylic acids of the empirical formula C8H17COOH, process for preparing these diesters, and use of these mixtures 有权
    二脱水己糖醇衍生物的二酯与经验式C8H17COOH的羧酸的混合物，制备这些二酯的方法以及这些混合物的使用

    公开(公告)号：US08258325B2

    公开(公告)日：2012-09-04

    申请号：US12523906

    申请日：2007-12-21

    申请人： Michael Grass ,  Norbert Scholz ,  Alfred Kaizik ,  Wilfried Bueschken ,  Hans-Gerd Lueken

    发明人： Michael Grass ,  Norbert Scholz ,  Alfred Kaizik ,  Wilfried Bueschken ,  Hans-Gerd Lueken

    IPC分类号： C07D307/93 ,  C07D493/00 ,  C08G73/06

    CPC分类号： C07D493/04 ,  C08K5/1535 ,  C08L27/06

    摘要： The present invention relates to a mixture comprising diesters of the formula (I) where R1 to R8═H or alkyl group having from 1 to 6 carbon atoms, where the R1 to R8 radicals may be the same or different, which is characterized in that at least two different diesters I are present in the mixture, said diesters differing in the structure of at least one of the carboxylic acid radicals C8H17COO present, to a process for preparing diesters of an isosorbide derivative of the formula I, in which a hexahydric alcohol and/or a monoanhydro or dianhydro derivative of the alcohol is esterified with a mixture of at least two different carboxylic acids of the empirical formula C8H17COOH, and to the use of these mixtures in paints, inks or coatings, in plastisols, adhesives or adhesive components, in sealants, as plasticizers in polymers or polymer components, as solvents, as lubricant oil components and as assistants in metal processing, and also PVC compositions or plastisols comprising PVC and from 5 to 250 parts by mass of the mixture per 100 parts by mass of PVC.

    摘要翻译： 本发明涉及包含式（I）的二酯的混合物，其中R 1至R 8 = H或具有1至6个碳原子的烷基，其中R 1至R 8基团可以相同或不同，其特征在于 混合物中存在至少两种不同的二酯I，所述二酯在存在的羧酸基团C 8 H 17 COO中的至少一种的结构上不同，制备式I的异山梨醇衍生物的二酯的制备方法，其中六元醇 和/或醇的单酐或二氢衍生物与经验式C 8 H 17 COOH的至少两种不同羧酸的混合物酯化，并且在涂料，油墨或涂料中，在增塑溶胶，粘合剂或粘合剂组分中使用这些混合物 在密封剂中，作为聚合物或聚合物组分中的增塑剂，作为溶剂，作为润滑油组分和作为金属加工助剂，以及PVC组合物或增塑溶胶，其包含PVC和 相对于100质量份的PVC，为5〜250质量份的混合物。

    IMAGING PROCEDURE PLANNING
    60.
    发明申请
    IMAGING PROCEDURE PLANNING 有权
    成像程序规划

    公开(公告)号：US20120089377A1

    公开(公告)日：2012-04-12

    申请号：US13321214

    申请日：2010-05-12

    申请人： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

    发明人： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

    IPC分类号： G06F17/50 ,  A61N5/00

    CPC分类号： G06T11/005 ,  A61B6/032 ,  A61B6/488

    摘要： A method includes generating with a processor (122) a three-dimensional subject specific model of structure of interest of a subject to be scanned based on a general three-dimensional model and pre-scan image data acquired by an imaging system (100) generating with the processor (122) an imaging plan for the subject based on the three-dimensional subject specific model.

    摘要翻译： 一种方法包括基于通常的三维模型和由成像系统（100）获取的预扫描图像数据，利用处理器（122）生成待扫描的对象的感兴趣结构的三维对象特定的模型， 与处理器（122）基于三维主题特定模型的对象的成像计划。