公开(公告)号：US09165385B2

公开(公告)日：2015-10-20

申请号：US13321214

申请日：2010-05-12

申请人： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

发明人： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

IPC分类号： G06F17/50 ,  G06T11/00 ,  A61B6/03 ,  A61B6/00

CPC分类号： G06T11/005 ,  A61B6/032 ,  A61B6/488

摘要： A method includes generating with a processor (122) a three-dimensional subject specific model of structure of interest of a subject to be scanned based on a general three-dimensional model and pre-scan image data acquired by an imaging system (100) generating with the processor (122) an imaging plan for the subject based on the three-dimensional subject specific model.

摘要翻译： 一种方法包括基于通常的三维模型和由成像系统（100）获取的预扫描图像数据，利用处理器（122）生成待扫描的对象的感兴趣结构的三维对象特定的模型， 与处理器（122）基于三维主题特定模型的对象的成像计划。

公开(公告)号：US20100316270A1

公开(公告)日：2010-12-16

申请号：US12808682

申请日：2008-12-16

申请人： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

发明人： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

IPC分类号： G06K9/00

CPC分类号： G06T11/006 ,  G06T2211/432

摘要： The invention proposes a 3D reconstruction of a body and a body contour from transversally truncated projections using a polyhedral object model. Possible clinical applications arise in the field of guided biopsies on acquisition systems equipped with a flat panel detector, where truncated projections cannot be avoided in thorax and abdominal scan protocols. From, for example, a rotational run both a 3D volume reconstruction and a surface mesh reconstruction of a patient's shape is generated and then visualized simultaneously in order to help the physician guide the biopsy device and judge the distance from the patient's skin to the tissue of interest inside the reconstructed volume.

摘要翻译： 本发明提出了使用多面体对象模型从横截面的突起中进行身体和身体轮廓的3D重建。 可能的临床应用出现在配备有平板检测器的采集系统上的引导活检领域，其中在胸部和腹部扫描方案中不能避免截断的突起。 例如，通过旋转运行，生成3D体积重建和患者形状的表面网格重建，然后同时可视化，以帮助医生引导活检装置并判断从患者皮肤到组织的距离 重建体积内的兴趣。

公开(公告)号：US20120089377A1

公开(公告)日：2012-04-12

申请号：US13321214

申请日：2010-05-12

申请人： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

发明人： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

IPC分类号： G06F17/50 ,  A61N5/00

CPC分类号： G06T11/005 ,  A61B6/032 ,  A61B6/488

摘要： A method includes generating with a processor (122) a three-dimensional subject specific model of structure of interest of a subject to be scanned based on a general three-dimensional model and pre-scan image data acquired by an imaging system (100) generating with the processor (122) an imaging plan for the subject based on the three-dimensional subject specific model.

摘要翻译： 一种方法包括基于通常的三维模型和由成像系统（100）获取的预扫描图像数据，利用处理器（122）生成待扫描的对象的感兴趣结构的三维对象特定的模型， 与处理器（122）基于三维主题特定模型的对象的成像计划。

公开(公告)号：US08446408B2

公开(公告)日：2013-05-21

申请号：US11997340

申请日：2006-07-12

申请人： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

发明人： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

IPC分类号： G06T15/00

CPC分类号： G06T11/005 ,  G06T2211/412

摘要： A method for generating or reconstruction of three-dimensional (3D) images corresponding to a structure of interest (60) including: acquiring a plurality of image projections corresponding to a structure of interest (60); applying a shape model (66) at a selected 3D seed point (64); and adapting the shape model (66) to represent the structure of interest (60), yielding an adapted shape model. A system for generation and reconstruction of three-dimensional (3D) images. The system (10) includes: an imaging system (12) configured to provide projection data corresponding to a structure of interest (60); and a controller (50) in operable communication with the imaging system (50). The controller (50) is configured to: receive the projection data, (64); apply a shape model (66) at a selected 3D seed point (64); and adapt the shape model (66) to represent the structure of interest (60), thereby yielding an adapted shape model.

摘要翻译： 一种用于生成或重建对应于感兴趣结构（60）的三维（3D）图像的方法，包括：获取与感兴趣结构相对应的多个图像投影（60）; 在选定的3D种子点（64）处应用形状模型（66）; 以及使形状模型（66）适应于表示感兴趣的结构（60），产生适应的形状模型。 一种用于三维（3D）图像的生成和重建的系统。 系统（10）包括：成像系统（12），被配置为提供对应于感兴趣结构（60）的投影数据; 以及与成像系统（50）可操作地通信的控制器（50）。 控制器（50）被配置为：接收投影数据（64）; 在选定的3D种子点（64）上应用形状模型（66）; 并适应形状模型（66）来表示感兴趣的结构（60），从而产生适应的形状模型。

公开(公告)号：US20110182492A1

公开(公告)日：2011-07-28

申请号：US13121800

申请日：2009-10-07

申请人： Michael Grass ,  Dirk Schaefer ,  Gert Antonius Franciscus Schoonenberg

发明人： Michael Grass ,  Dirk Schaefer ,  Gert Antonius Franciscus Schoonenberg

IPC分类号： G06K9/00 ,  G21K1/04

CPC分类号： G06T11/008 ,  A61B6/06 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/504 ,  A61B6/5247 ,  A61B6/542 ,  G06F19/00 ,  G06F19/321 ,  G06T15/08 ,  G06T2211/404 ,  G16H40/63

摘要： The present invention refers to an angiographic image acquisition system and method which can beneficially be used in the scope of minimally invasive image-guided interventions. In particular, the present invention relates to a system and method for graphically visualizing a pre-interventionally virtual 3D representation of a patient's coronary artery tree's vessel segments in a region of interest of a patient's cardiovascular system to be three-dimensionally reconstructed. Optionally, this 3D representation can then be fused with an intraoperatively acquired fluoroscopic 2D live image of an interventional tool. According to the present invention, said method comprises the steps of subjecting the image data set of the 3D representation associated with the precalculated optimal viewing angle to a 3D segmentation algorithm (S4) in order to find the contours of a target structure or lesion to be examined and interventionally treated within a region of interest and automatically adjusting (S5) a collimator wedge position and/or aperture of a shutter mechanism used for collimating an X-ray beam emitted by an X-ray source of a C-arm-based 3D rotational angiography device or rotational gantry-based CT imaging system to which the patient is exposed during an image-guided radiographic examination procedure based on data obtained as a result of said segmentation which indicate the contour and size of said target structure or lesion. The aim is to reduce the region of interest to a field of view that covers said target structure or lesion together with a user-definable portion of the surrounding vasculature.

摘要翻译： 本发明涉及一种血管造影图像采集系统和方法，可有利地用于微创图像引导干预的范围。 特别地，本发明涉及一种用于以图形方式可视化患者心血管系统感兴趣区域中的患者冠状动脉树血管段的预先介入虚拟3D表示以进行三维重构的系统和方法。 可选地，该3D表示随后可以与介入工具的术中获取的荧光透视2D实况图像融合。 根据本发明，所述方法包括以下步骤：将与预先计算的最佳视角相关联的3D表示的图像数据集进行3D分割算法（S4），以便将目标结构或病变的轮廓找到为 在感兴趣区域内进行检查和介入处理，并自动调整（S5）用于准直由基于C臂的3D的X射线源发射的X射线束的快门机构的准直器楔位置和/或孔径 旋转血管造影装置或基于旋转台架的CT成像系统，其中基于由所述分割结果获得的指示所述目标结构或病变的轮廓和大小的图像引导放射线检查程序期间所述患者暴露于所述CT成像系统。 目的是将感兴趣的区域减少到覆盖所述目标结构或病变的视野以及周围脉管系统的用户可定义的部分。

公开(公告)号：US20100189337A1

公开(公告)日：2010-07-29

申请号：US12668043

申请日：2008-07-08

申请人： Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

发明人： Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

IPC分类号： G06K9/00

CPC分类号： A61B6/504 ,  A61B6/4441 ,  A61B6/463 ,  A61B6/481 ,  A61B6/541 ,  G06T7/0012 ,  G06T7/564 ,  G06T7/596 ,  G06T7/60 ,  G06T11/006 ,  G06T17/00 ,  G06T2200/08 ,  G06T2207/10112 ,  G06T2207/10116 ,  G06T2207/20044 ,  G06T2207/30101 ,  G06T2211/404 ,  G06T2211/412

摘要： A method and an apparatus for acquiring 3-dimensional images of coronary vessels (11), particularly of coronary veins, is proposed. 2-dimensional X-ray images (13) are acquired within a same phase of a cardiac motion. Then, a 3-dimensional centerline model (15) is generated based on these 2-dimensional images. From 2-dimensional projections of the centerline model into respective projection planes, the local diameters (w) of the vessels in the projection plane can be derived. Having the diameters, a 3-dimensional hull model of the vessel system can be generated and, optionally, 4-dimensional information about the vessel movement can be derived.

摘要翻译： 提出了一种用于获取冠状血管（11），特别是冠状静脉的三维图像的方法和装置。 在心脏运动的相同相位中获取2维X射线图像（13）。 然后，基于这些二维图像生成3维中心线模型（15）。 从中心线模型的二维投影到相应的投影平面，可以推导投影平面中容器的局部直径（w）。 具有直径，可以产生容器系统的3维船体模型，并且可以导出关于船只运动的4维信息。

公开(公告)号：US20090238412A1

公开(公告)日：2009-09-24

申请号：US12305996

申请日：2007-06-18

申请人： Michael Grass ,  Dirk Schaefer ,  Babak Movassaghi

发明人： Michael Grass ,  Dirk Schaefer ,  Babak Movassaghi

IPC分类号： G06T7/20 ,  G06T7/00

CPC分类号： A61B6/504 ,  A61B6/032 ,  A61B6/469 ,  A61B6/5264 ,  A61B6/527 ,  A61B6/541

摘要： The analysis of a stenosis of a coronary vessel in three dimensions requires a motion compensated reconstruction. According to an exemplary embodiment of the present invention, an examination apparatus for local motion compensated reconstruction data set is provided, wherein the local motion compensated reconstruction vectors relating to a start point and an end point of the stenosis.

摘要翻译： 三维冠状动脉血管狭窄的分析需要运动补偿重建。 根据本发明的示例性实施例，提供了一种用于局部运动补偿重建数据集的检查装置，其中与狭窄的起始点和终点有关的局部运动补偿重建向量。

公开(公告)号：US09087404B2

公开(公告)日：2015-07-21

申请号：US13697445

申请日：2011-04-25

申请人： Eberhard S. Hansis ,  Dirk Schaefer ,  Michael Grass

发明人： Eberhard S. Hansis ,  Dirk Schaefer ,  Michael Grass

IPC分类号： G01N23/04 ,  G06T1/00 ,  G06T11/00

CPC分类号： G06T11/008 ,  G06T11/006 ,  G06T2211/432

摘要： Computed tomography (CT) reconstruction includes reconstructing an axially extended reconstructed image from a measured cone beam x-ray projection data set (Pm), optionally having an off-center geometry. The reconstructing is performed for an extended volume (eFOV) comprising a reconstructable volume (rFOV) of the measured cone beam x ray data set that is extended along the axial direction. The projection data set may be weighted in the volume domain. Iterative reconstruction may be used, including initializing a constant volume and performing one or more iterations employing a first iterative update followed by one or more iterations employing a second, different iterative update. Alternatively, backprojection filtration (BPF) reconstruction may be used, including transforming the projection data set to a new geometry including finite differences between neighboring projection views and performing BPF using Hilbert filtering along a plurality of different directions and averaging the resultant reconstructed images to generate the final reconstructed image.

摘要翻译： 计算机断层摄影（CT）重建包括从测量的锥形束X射线投影数据集（Pm）重建轴向延伸的重建图像，可选地具有偏心几何。 对包括沿轴向延伸的测量的锥形束x射线数据集的可重建体积（rFOV）的扩展体积（eFOV）进行重建。 投影数据集可以在体积域中加权。 可以使用迭代重建，包括初始化恒定体积并且使用第一迭代更新执行一个或多个迭代，随后使用第二，不同迭代更新的一个或多个迭代。 或者，可以使用反投影过滤（BPF）重建，包括将投影数据集变换为包括相邻投影视图之间的有限差异的新几何，并且使用沿着多个不同方向的希尔伯特滤波来执行BPF，并平均所得到的重建图像以产生 最终重建图像。

公开(公告)号：US08478014B2

公开(公告)日：2013-07-02

申请号：US12990817

申请日：2009-05-05

申请人： Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

发明人： Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

IPC分类号： G06K9/00

CPC分类号： G06T11/005 ,  G06T7/564 ,  G06T2211/412

摘要： The present invention relates to an apparatus for generating an image of a moving object, wherein a movement of the object comprises a multiple of moving phases. The apparatus comprises a measured detection data providing unit (20) for providing measured detection data of the moving object, which have been detected by using a detection process and which are assigned to the moving phases. The apparatus comprises further a reconstruction unit (13) for reconstructing an image object of the object from the provided measured detection data and an adaptation unit (18) for adapting the image object for different moving phases such that simulated detection data are adapted to the measured detection data of the respective moving phase, wherein the simulated detection data are determined by simulating the detection process, which has been used for detecting the measured detection data assigned to the respective moving phase, with the image object.

摘要翻译： 本发明涉及一种用于生成移动物体的图像的装置，其中物体的移动包括多个移动相位。 该装置包括测量检测数据提供单元（20），用于提供已经通过使用检测处理检测并被分配给运动相位的移动物体的测量检测数据。 所述设备还包括用于根据所提供的测量的检测数据重建对象的图像对象的重建单元（13）和用于使图像对象适应不同的移动阶段的适配单元（18），使得模拟的检测数据适应于所测量的 检测数据，其中通过模拟已经用于检测分配给各个运动相位的测量检测数据的检测过程与图像对象来确定模拟检测数据。

公开(公告)号：US20130116551A1

公开(公告)日：2013-05-09

申请号：US13810292

申请日：2011-07-15

申请人： Raoul Florent ,  Vincent Auvray ,  Michael Grass ,  Dirk Schaefer ,  Gert Schoonenberg

发明人： Raoul Florent ,  Vincent Auvray ,  Michael Grass ,  Dirk Schaefer ,  Gert Schoonenberg

IPC分类号： A61B6/02

CPC分类号： A61B6/022 ,  A61B6/12 ,  A61B6/4441 ,  A61B6/463 ,  A61B6/487 ,  A61B6/504 ,  A61B6/5223 ,  A61B6/5235 ,  A61B2090/364 ,  A61B2090/367

摘要： The present invention relates to 3D-originated cardiac roadmapping. In order to improve the accuracy of the information provided to the user as navigation information, without any additional burden to the patient such as additional X-ray dose, a method is described comprising the steps of a) providing 3D+t image data of a vascular structure of an object; b) acquiring two-dimensional image data of the object, which object comprises the vascular structure, the 2D image data comprising at least one 2D image; c) projecting the vascular structure, thereby generating a plurality of mask images on the basis of a 3D+t image data; d) registering the at least one 2D image with one of the plurality of the mask images, wherein the registration comprises finding the maximum of a similarity factor between the mask images and the at least one 2D image; e) generating a combination of the at least one 2D image and a projection of the vascular structure on the basis of the 3D+t image data according to the registration; and f) displaying the combination as a guiding vessel tree projection. Thus improved cardiac roadmapping in form of a topographical roadmapping is provided since the roadmapping is based on three-dimensional data.

摘要翻译： 本发明涉及3D起源的心脏路线图。 为了提高作为导航信息提供给用户的信息的准确性，对病人没有任何额外的负担，例如额外的X射线剂量，描述了一种方法，其包括以下步骤：a）提供一个 物体的血管结构; b）获取所述对象的二维图像数据，所述对象包括所述血管结构，所述2D图像数据包括至少一个2D图像; c）投影血管结构，从而基于3D + t图像数据生成多个掩模图像; d）使用所述多个掩模图像之一登记所述至少一个2D图像，其中所述注册包括找到所述掩模图像与所述至少一个2D图像之间的相似性因子的最大值; e）根据所述注册，基于所述3D + t图像数据生成所述至少一个2D图像和所述血管结构的投影的组合; 以及f）将组合显示为引导血管树投影。 因此，由于路线图基于三维数据，所以提供了形成路面图的形式的改进的心脏路线图。