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51.发明申请公开(公告)号：US20110252711A1
公开(公告)日：2011-10-20
申请号：US13077426
申请日：2011-03-31
CPC分类号： B01J3/062 , B01J2203/062 , B01J2203/0655 , B01J2203/0685 , B24D99/005 , B82Y30/00 , C01B32/28 , C04B35/52 , C04B35/6303 , C04B35/645 , C04B37/02 , C04B2235/3206 , C04B2235/3208 , C04B2235/3215 , C04B2235/3826 , C04B2235/3847 , C04B2235/386 , C04B2235/422 , C04B2235/427 , C04B2235/5248 , C04B2235/5288 , C04B2235/5436 , C04B2235/5445 , C04B2235/5454 , C04B2235/5472 , C04B2237/363 , C04B2237/401
摘要： A method of forming a polycrystalline diamond comprises derivatizing a nanodiamond to form functional groups, and combining the derivatized nanodiamond with a microdiamond having an average particle size greater than that of the derivatized nanodiamond, and a metal solvent-catalyst. A polycrystalline diamond compact is prepared by adhering the polycrystalline diamond to a support, and an article such as a cutting tool may be prepared from the polycrystalline diamond compact.
摘要翻译： 形成多晶金刚石的方法包括使纳米金刚石衍生形成官能团，并将衍生的纳米金刚石与平均粒径大于衍生的纳米金刚石的微米金刚石和金属溶剂 - 催化剂结合。 通过将多晶金刚石粘附到支撑体上制备多晶金刚石致密体，并且可以从多晶金刚石复合体制备诸如切割工具的制品。
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52.发明授权公开(公告)号：US10946091B2
公开(公告)日：2021-03-16
申请号：US16392274
申请日：2019-04-23
申请人： Gaurav Agrawal
发明人： Gaurav Agrawal
IPC分类号： A61K39/395 , A61K39/40 , A61K31/435 , A61K31/133 , A61K31/4164 , A61K31/496 , A61K31/498 , A61K31/7048 , A61K33/00 , A61K39/00 , A23G3/36 , A23G4/06 , A23G9/32 , A23C9/123 , A23G4/12 , A23G9/36
摘要： In alternative embodiments, the invention provides a “triple combination” therapy for treating, ameliorating and preventing Crohn's Disease (or Crohn syndrome, terminal or distal ileitis or regional enteritis) or related disorders and conditions in mammals, such as paratuberculosis in mammals, or Johne's disease, including genetically-predisposed and chronic disorders, where the microbial or bacterial flora of the bowel is at least one causative or symptom-producing factor; and compositions for practicing same. In alternative embodiments, methods and compositions of the invention comprise or comprise use of therapies, medications, formulations and pharmaceuticals comprising active agents that can suppress or eradicate the microbiota super-infection that causes Crohn's Disease or paratuberculosis infection in mammals. In alternative embodiments, the methods and uses of the invention for treating, ameliorating and preventing Crohn's Disease and complications of Crohn's Disease, or related disorders and conditions in mammals, such as paratuberculosis in mammals, or Johne's disease, comprises administration to an individual (human or mammal) in need thereof: (1) an anti-TNFα composition, or a composition capable of down-modulating TNFα activity; (2) a Hyperbaric Oxygen Treatment, or HBOT; and (3) an anti Mycobacterium avium sub species paratuberculosis (MAP) (an anti-MAP) agent, composition or therapy.
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53.发明申请公开(公告)号：US20170050159A1
公开(公告)日：2017-02-23
申请号：US15342177
申请日：2016-11-03
申请人： Zhiyue Xu , Gaurav Agrawal
发明人： Zhiyue Xu , Gaurav Agrawal
CPC分类号： B01J2/006 , B01J2/16 , B22F1/02 , B22F1/025 , B22F2202/15 , C08J5/005 , C08J2323/06 , C08J2323/12 , C08J2325/02 , C08J2325/18 , C08J2333/02 , C08J2333/12 , C08J2335/04 , C08J2361/16
摘要： A method of making a nanostructure-reinforced composite comprises providing matrix particles in a reactor; fluidizing the matrix particles; introducing a nanostructure material into the reactor; homogeneously dispersing the nanostructure material; uniformly depositing the nanostructure material on the matrix particles to form a composite powder; generating a nanostructure on the matrix particles from the nanostructure material; and processing the composite powder to form the nanostructure-reinforced composite having a matrix formed from the matrix particles. The nanostructures are evenly distributed in the matrix of the nanostructure-reinforced composite.
摘要翻译： 制备纳米结构增强复合材料的方法包括在反应器中提供基体颗粒; 流化基质颗粒; 将纳米结构材料引入反应器; 均匀分散纳米结构材料; 将纳米结构材料均匀地沉积在基体颗粒上以形成复合粉末; 从纳米结构材料在基体颗粒上产生纳米结构; 并处理复合粉末以形成具有由基质颗粒形成的基体的纳米结构增强复合材料。 纳米结构均匀分布在纳米结构增强复合材料的基体中。
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公开(公告)号：US09181781B2
公开(公告)日：2015-11-10
申请号：US13173944
申请日：2011-06-30
申请人： Gaurav Agrawal , Zhiyue Xu , Ping Duan , James Goodson , James B. Crews
发明人： Gaurav Agrawal , Zhiyue Xu , Ping Duan , James Goodson , James B. Crews
摘要： A method of making a reconfigurable article is disclosed. The method includes providing a powder comprising a plurality of base material particles. The method also includes providing a powder comprising a plurality of removable material particles; and forming a base article from the base material comprising a plurality of removable material particles. A method of using a reconfigurable article is also disclosed. The method includes forming a base article, the base article comprising a base material and a removable material, wherein the base article comprises a downhole tool or component. The method also includes inserting the base article into a wellbore. The method further includes performing a first operation utilizing the base article; exposing the removable material of the base article to a wellbore condition that is configured to remove the removable material and form a modified article; and performing a second operation using the article.
摘要翻译： 公开了制造可重构产品的方法。 该方法包括提供包含多个基材颗粒的粉末。 该方法还包括提供包含多个可除去材料颗粒的粉末; 以及从所述基底材料形成包括多个可除去的材料颗粒的基底制品。 还公开了一种使用可重构产品的方法。 所述方法包括形成基底制品，所述基底制品包括基底材料和可移除材料，其中所述基底制品包括井下工具或部件。 该方法还包括将基底物品插入井孔中。 所述方法还包括利用所述基础物品执行第一操作; 将基础制品的可移除材料暴露于井眼状态，其构造成移除可移除材料并形成经修改的制品; 以及使用所述物品执行第二操作。
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公开(公告)号：US09109429B2
公开(公告)日：2015-08-18
申请号：US12633678
申请日：2009-12-08
申请人： Zhiyue Xu , Gaurav Agrawal
发明人： Zhiyue Xu , Gaurav Agrawal
CPC分类号： E21B41/00 , B22F1/025 , B22F2998/00 , C22C1/04 , C22C1/0408 , C22C1/0416 , C22C1/10 , C22C32/00 , B22F1/0044 , B22F1/02
摘要： An engineered dispersed particle-cellular nanomatrix composite material is disclosed. The engineered dispersed particle-cellular nanomatrix composite material is configured for contact with a fluid and configured to provide a selectable and controllable transition from one of a first strength condition to a second strength condition that is lower than a functional strength threshold, or a first weight loss amount to a second weight loss amount that is greater than a weight loss limit, as a function of a time in contact with the fluid.
摘要翻译： 公开了工程分散的颗粒 - 细胞纳米线性复合材料。 工程分散的颗粒 - 细胞纳米层复合材料被配置为与流体接触并且被配置为提供从第一强度条件到低于功能强度阈值的第二强度条件之一的可选择和可控的过渡，或第一重量 作为与流体接触的时间的函数的大于重量损失极限的第二减重量的损失量。
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公开(公告)号：US09022107B2
公开(公告)日：2015-05-05
申请号：US13927761
申请日：2013-06-26
申请人： Gaurav Agrawal , Zhiyue Xu
发明人： Gaurav Agrawal , Zhiyue Xu
摘要： A dissolvable tool includes, a body with a surface having at least one perforation therethrough, the at least one perforation being dimensioned to control a rate of intrusion of an environment reactive with at least a portion of the dissolvable tool located below the surface.
摘要翻译： 可溶解工具包括具有表面的主体，其具有穿过其中的至少一个穿孔，所述至少一个穿孔的尺寸被设计成控制与位于表面下方的可溶解工具的至少一部分反应的环境的侵入速率。
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公开(公告)号：US20130334098A1
公开(公告)日：2013-12-19
申请号：US13526847
申请日：2012-06-19
申请人： Oleg A. Mazyar , Gaurav Agrawal
发明人： Oleg A. Mazyar , Gaurav Agrawal
IPC分类号： C10G71/00
CPC分类号： C10G1/047
摘要： A method for decomposing an asphaltene particle includes contacting the asphaltene particle with an intercalating agent; and reacting the intercalating agent to increase a distance between asphaltene molecules in the asphaltene particle to decompose the asphaltene particle. In a method for producing decomposed asphaltene, the method includes disposing an intercalating agent in an oil environment; contacting an asphaltene particle in the oil environment with the intercalating agent; reacting the intercalating agent to produce product molecules; and decomposing the asphaltene particle to produce decomposed asphaltene.
摘要翻译： 分解沥青质颗粒的方法包括使沥青质颗粒与嵌入剂接触; 并使插入剂反应以增加沥青质颗粒中沥青质分子之间的距离，以分解沥青质颗粒。 在分解沥青质的制造方法中，所述方法包括在油环境中配置嵌入剂; 使油环境中的沥青质颗粒与嵌入剂接触; 使插层剂反应生成产物分子; 并分解沥青质颗粒以产生分解的沥青质。
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公开(公告)号：US20130220883A1
公开(公告)日：2013-08-29
申请号：US13404858
申请日：2012-02-24
IPC分类号： C10C3/02
CPC分类号： C10G1/045
摘要： A method for decomposing an asphaltene particle includes contacting the asphaltene particle with an intercalating agent and separating an asphaltene molecule from the asphaltene particle to decompose the asphaltene particle. Dispersing an asphaltene particle includes functionalizing the asphaltene particle and contacting the asphaltene particle with a solvent to disperse the asphaltene particle. Such asphaltene particle decomposition and dispersal can be used in a method for improving oil recovery that includes disposing a reagent in an oil environment; contacting an asphaltene particle with the reagent; decomposing the asphaltene particle to produce decomposed asphaltene; and displacing the decomposed asphaltene to improve oil recovery.
摘要翻译： 分解沥青质颗粒的方法包括使沥青质颗粒与嵌入剂接触并将沥青质分子与沥青质颗粒分离以分解沥青质颗粒。 分散沥青质颗粒包括使沥青质颗粒官能化并使沥青质颗粒与溶剂接触以分散沥青质颗粒。 这种沥青质颗粒分解和分散可用于提高油回收的方法，包括在油环境中设置试剂; 使沥青质颗粒与试剂接触; 分解沥青质颗粒产生分解沥青质; 并使分解的沥青质置换以改善油的回收率。
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59.发明申请公开(公告)号：US20130059074A1
公开(公告)日：2013-03-07
申请号：US13224443
申请日：2011-09-02
申请人： Zhiyue Xu , Gaurav Agrawal
发明人： Zhiyue Xu , Gaurav Agrawal
CPC分类号： B01J2/006 , B01J2/16 , B22F1/02 , B22F1/025 , B22F2202/15 , C08J5/005 , C08J2323/06 , C08J2323/12 , C08J2325/02 , C08J2325/18 , C08J2333/02 , C08J2333/12 , C08J2335/04 , C08J2361/16
摘要： A method of making a nanostructure-reinforced composite comprises providing matrix particles in a reactor; fluidizing the matrix particles; introducing a nanostructure material into the reactor; homogeneously dispersing the nanostructure material; uniformly depositing the nanostructure material on the matrix particles to form a composite powder; generating a nanostructure on the matrix particles from the nanostructure material; and processing the composite powder to form the nanostructure-reinforced composite having a matrix formed from the matrix particles. The nanostructures are evenly distributed in the matrix of the nanostructure-reinforced composite.
摘要翻译： 制备纳米结构增强复合材料的方法包括在反应器中提供基体颗粒; 流化基质颗粒; 将纳米结构材料引入反应器; 均匀分散纳米结构材料; 将纳米结构材料均匀地沉积在基体颗粒上以形成复合粉末; 从纳米结构材料在基体颗粒上产生纳米结构; 并处理复合粉末以形成具有由基质颗粒形成的基体的纳米结构增强复合材料。 纳米结构均匀分布在纳米结构增强复合材料的基体中。
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公开(公告)号：US20130000985A1
公开(公告)日：2013-01-03
申请号：US13173992
申请日：2011-06-30
申请人： Gaurav Agrawal , Zhiyue Xu , Ping Duan , James Goodson , Andre Porter , James B. Crews
发明人： Gaurav Agrawal , Zhiyue Xu , Ping Duan , James Goodson , Andre Porter , James B. Crews
IPC分类号： E21B12/00
CPC分类号： E21B41/00
摘要： A reconfigurable downhole article is disclosed. The article comprises a base material. The article also comprises a removable material disposed on or within the base material that is configured for removal from the base material in response to a wellbore condition, wherein the base material and the removable material define a base article that is configured to perform a first function, and wherein upon removal of the removable material, the base material defines a modified article that is configured to perform a second function that is different than the first function.
摘要翻译： 公开了可重新配置的井下物品。 该制品包括基材。 所述制品还包括设置在所述基材上或内部的可移除材料，所述可移除材料构造成响应于井筒状况从所述基材移除，其中所述基材和所述可移除材料限定被配置为执行第一功能的基底制品 ，并且其中在移除所述可移除材料时，所述基材限定被配置为执行与所述第一功能不同的第二功能的经修饰制品。
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