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204 条记录 (耗时 0.06 秒)

    Systems and methods for electrosurgical treatment of tissue in the brain and spinal cord
    52.
    发明授权
    Systems and methods for electrosurgical treatment of tissue in the brain and spinal cord 有权
    用于电外科治疗脑和脊髓组织的系统和方法

    公开(公告)号：US06322549B1

    公开(公告)日：2001-11-27

    申请号：US09478729

    申请日：2000-01-06

    申请人： Philip E. Eggers ,  Hira V. Thapliyal

    发明人： Philip E. Eggers ,  Hira V. Thapliyal

    IPC分类号： A61M3100

    CPC分类号： A61B18/1482 ,  A61B18/14 ,  A61B2018/00434 ,  A61B2018/00583 ,  A61B2018/1467 ,  A61B2018/1472 ,  A61B2018/162 ,  A61M3/0241 ,  A61N1/06

    摘要： The present invention provides systems and methods for selectively applying electrical energy to a target location within a patient's brain and spinal cord. The systems and methods of the present invention are particularly useful for treating cerebrovascular diseases, such as vessel occlusion, or for the volumetric removal or ablation of intracranial tumors or Arteriovenous Malformations (AVMs). The method of the present invention comprises positioning an electrosurgical probe or catheter adjacent the target site so that one or more electrode terminal(s) are brought into at least partial contact or close proximity with a body structure within the patient's head or neck, such as tumor tissue or an occlusion within a blood vessel. High frequency voltage is then applied between the electrode terminal(s) and one or more return electrode(s) to volumetrically remove or ablate at least a portion of the body structure in situ. In specific embodiments, the high frequency voltage is sufficient to effect the dissociation or disintegration of organic molecules into non-viable atoms and molecules. Specifically, the present invention converts the solid tissue cells into non-condensable gases that are no longer intact or viable, and thus, not capable of spreading viral or bacterial particles to other portions of the body structure.

    摘要翻译： 本发明提供用于选择性地将电能施加到患者脑和脊髓内的目标位置的系统和方法。 本发明的系统和方法特别可用于治疗脑血管疾病，例如血管阻塞，或用于体内移除或消除颅内肿瘤或动静脉畸形（AVM）。 本发明的方法包括将电外科探头或导管定位在靶位置附近，使得一个或多个电极端子与患者头部或颈部内的身体结构至少部分接触或接近，例如 肿瘤组织或血管内的闭塞。 然后将高频电压施加在电极端子和一个或多个返回电极之间，以便原位移动或消除身体结构的至少一部分。 在具体实施方案中，高频电压足以使有机分子解离或分解成非活的原子和分子。 具体而言，本发明将固体组织细胞转化为不再完整或不活动的不可冷凝气体，因此不能将病毒或细菌颗粒传播到身体结构的其他部分。

    Methods and apparatus for advancing catheters through severely occluded body lumens
    60.
    发明授权
    Methods and apparatus for advancing catheters through severely occluded body lumens 失效
    通过严重闭塞的体腔推进导管的方法和装置

    公开(公告)号：US5419767A

    公开(公告)日：1995-05-30

    申请号：US111367

    申请日：1993-08-24

    申请人： Philip E. Eggers ,  Hira V. Thapliyal

    发明人： Philip E. Eggers ,  Hira V. Thapliyal

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B18/00 ,  A61B18/14 ,  A61B19/00 ,  A61F2/02 ,  A61M25/01 ,  A61M37/00

    CPC分类号： A61B18/149 ,  A61B18/1492 ,  A61M25/0158 ,  A61B18/1402 ,  A61B2017/00026 ,  A61B2017/00084 ,  A61B2017/00097 ,  A61B2017/00101 ,  A61B2017/00247 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/22001 ,  A61B2017/22038 ,  A61B2018/00029 ,  A61B2018/0016 ,  A61B2018/00196 ,  A61B2018/00392 ,  A61B2018/00642 ,  A61B2018/00678 ,  A61B2018/00726 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/00886 ,  A61B2018/1213 ,  A61B2018/126 ,  A61B2018/1497 ,  A61B2018/162 ,  A61B2090/378 ,  A61B2218/002 ,  A61F2/2493

    摘要： A catheter system is provided that includes an electrode array near the distal end of the catheter. High frequency current is supplied between the electrodes of the array and a common electrode to cause heating of material lying between the electrodes. The catheter may include means for steering it through the lumen. In a preferred embodiment, the steering means includes a plurality of steering wires in contact with the catheter body. The steering wires may be formed of a shape-memory alloy. Wires of such an alloy may be made to contract when heated above a preselected transition temperature. The wires may be heated by the selective conduction of electrical current through them. Conduction of current through the steering wires is controlled based on the current flowing through the electrodes of the array. An inflatable balloon may be included proximal to the electrode array for dilating the vessel after the occlusion has been penetrated by the electrode array. The balloon may be shielded and protected behind a portion of the catheter having a diameter greater than the diameter of the uninflated balloon disposed about the catheter body. The catheter will include means for protecting the walls of the vessel from exposure to electrical current from the electrodes. This will commonly include switching means or other means for current control. The vessel wall may also be protected by setting the electrodes back some distance from the outer edge of the distal tip.

    摘要翻译： 提供了一种导管系统，其包括靠近导管远端的电极阵列。 在阵列的电极和公共电极之间提供高频电流以引起位于电极之间的材料的加热。 导管可以包括用于使其通过管腔的装置。 在优选实施例中，转向装置包括与导管主体接触的多个操纵线。 转向线可以由形状记忆合金形成。 当加热到预选的转变温度以上时，可使这种合金的电线收缩。 可以通过选择性地导通电流来加热导线。 基于流过阵列电极的电流来控制通过导线的电流传导。 可以在电极阵列附近包括可充气气球，用于在闭塞已经被电极阵列穿透之后扩张血管。 导管的一部分的直径大于设置在导管主体周围的未膨胀球囊的直径的一部分导管上的气囊可被屏蔽和保护。 导管将包括用于保护容器壁免受来自电极的电流的装置。 这通常包括开关装置或其他用于电流控制的装置。 血管壁也可以通过将电极设置回远离远端尖端的外缘一些距离来保护。