公开(公告)号：US10321989B2

公开(公告)日：2019-06-18

申请号：US15275903

申请日：2016-09-26

申请人： Medtentia International Ltd. Oy

发明人： Olli Keränen

IPC分类号： A61F2/24

摘要： The present disclosure relates to an arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve. With the method or the arrangement, leakage or regurgitation between a prosthetic heart valve and the surrounding valve tissue is prevented. In one embodiment, an arrangement for replacement or repair of a native heart valve is provided, which comprises a loop-shaped support 41 and a prosthetic heart valve 70 and wherein an outer segment 32 of the loop-shaped support 41 is positionable towards surrounding valve tissue of a native heart valve and wherein an outer surface 74 of the prosthetic heart valve 70 is positionable towards an inner segment 34 of the loop-shaped support 41 so as to prevent paravalvular leakage or regurgitation between the prosthetic heart valve 70 and the surrounding valve tissue of the native heart valve.

公开(公告)号：US10130471B2

公开(公告)日：2018-11-20

申请号：US14762428

申请日：2014-01-27

申请人： Medtentia International Ltd Oy

发明人： Olli Keränen ,  Jani Virtanen ,  Mark Pugh ,  Ger O'Carroll ,  Adrian Moran

IPC分类号： A61F2/24

摘要： Disclosed is a medical system for short time replacement and repair of a native valve, which comprises an artificial valve (502); and a device for collecting and arranging chordae and/or leaflets to hold and/or stabilize the artificial valve in a desired position, the device comprising: a unit for grasping a plurality of chordae and/or leaflets. The system and/or device allows for fast and easy replacement of a native valve, fast and easy positioning of a temporary artificial valve, and more time for medical personnel to make decisions, prepare and/or perform surgery/medical intervention.

公开(公告)号：US20170273788A1

公开(公告)日：2017-09-28

申请号：US15509458

申请日：2015-09-08

申请人： Medtentia International Ltd Oy

发明人： Ger O'Carroll ,  Mark Pugh ,  Adrian Moran ,  Hans-Reinhard Zerkowski ,  Olli Keränen

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2448 ,  A61F2/2454 ,  A61F2230/0091 ,  A61F2250/0029 ,  A61F2250/0036 ,  A61F2250/0071

摘要： An annuloplasty implant comprising an inner core of a shape memory material, an outer covering arranged radially outside said inner core material to cover at least part of said inner core, wherein said outer covering is resilient to conform to said inner core during movement of said shape memory material, wherein said outer covering comprises a material having surface properties to promote endothelialization. Two portions of the implant may be joined by a recess to be flexible with respect to each other by a bending motion at the recess. The two portions may also have a predefined breaking point at the recess.

公开(公告)号：US09474599B2

公开(公告)日：2016-10-25

申请号：US14373878

申请日：2013-01-24

申请人： Medtentia International Ltd. Oy

发明人： Olli Keränen

IPC分类号： A61F2/24

CPC分类号： A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2442 ,  A61F2/2445 ,  A61F2/2466 ,  A61F2230/0013 ,  A61F2230/008 ,  A61F2230/0091 ,  A61F2250/006

摘要： The present disclosure relates to an arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve. With the method or the arrangement, leakage or regurgitation between a prosthetic heart valve and the surrounding valve tissue is prevented. In one embodiment, an arrangement for replacement or repair of a native heart valve is provided, which comprises a loop-shaped support (41) and a prosthetic heart valve (70) and wherein an outer segment (32) of the loop-shaped support (41) is positionable towards surrounding valve tissue of a native heart valve and wherein an outer surface (74) of the prosthetic heart valve (70) is positionable towards an inner segment (34) of the loop-shaped support (41) so as to prevent paravalvular leakage or regurgitation between the prosthetic heart valve (70) and the surrounding valve tissue of the native heart valve.

摘要翻译： 本公开涉及一种布置，环形支撑件，假体心脏瓣膜以及修复或替换天然心脏瓣膜的方法。 通过该方法或布置，可以防止假体心脏瓣膜和周围的阀组织之间的渗漏或反流。 在一个实施例中，提供了一种用于置换或修复天然心脏瓣膜的装置，其包括环形支撑件（41）和假体心脏瓣膜（70），并且其中所述环形支撑件的外部段（32） （41）能够朝向天然心脏瓣膜的周围瓣膜组织定位，并且其中所述假体心脏瓣膜（70）的外表面（74）能够朝向所述环形支撑件（41）的内部段（34）定位，以便 以防止假体心脏瓣膜（70）与天然心脏瓣膜的周围瓣膜组织之间的瓣膜溢出或反流。

公开(公告)号：US20160095705A1

公开(公告)日：2016-04-07

申请号：US14891939

申请日：2014-05-21

申请人： MEDTENTIA INTERNATIONAL LTD OY

发明人： Olli Keränen ,  Hans-Reinhard Zerkowski

IPC分类号： A61F2/24

摘要： A medical system (300) is disclosed for treating a defective mitral valve (MV) having an annulus (A). The system (300) comprises in combination a removable and flexible elongate displacement unit (301) for temporary insertion into a coronary sinus (CS) adjacent the valve, wherein the displacement unit has a delivery state for delivery into said CS, and an activated state to which the displacement unit is temporarily and reversibly transferable from the delivery state. The displacement unit comprises a proximal reversibly expandable portion (302), a distal anchoring portion (303) being movable in relation to the proximal expandable portion in a longitudinal direction of the displacement unit to the activated state in which the shape of the annulus is modified to a modified shape (A′); and an annuloplasty device (102) for permanent fixation at the mitral valve annulus by annuloplasty of the valve when the modified shape is obtained. The annuloplasty device (102) comprises a fixation structure that is adapted to retain the modified shape.

摘要翻译： 公开了用于治疗具有环（A）的有缺陷的二尖瓣（MV）的医疗系统（300）。 系统（300）组合包括用于临时插入邻近瓣膜的冠状窦（CS）的可移除和柔性的细长位移单元（301），其中位移单元具有用于递送到所述CS的输送状态和激活状态 位移单元临时并可逆地从输送状态转移到该位移单元。 位移单元包括近端可逆扩展部分（302），远侧锚固部分（303）可相对于位移单元的纵向方向上的近端可扩张部分移动到环形形状被修改的激活状态 （A'）; 以及瓣膜成形术装置（102），用于当获得改良形状时通过瓣膜瓣膜成形术在二尖瓣环处永久固定。 瓣膜成形术装置（102）包括适于保持修改形状的固定结构。

公开(公告)号：US20150359628A1

公开(公告)日：2015-12-17

申请号：US14762413

申请日：2014-01-27

申请人： MEDTENTIA INTERNATIONAL LTD OY

发明人： Olli Keränen

IPC分类号： A61F2/24

CPC分类号： A61F2/2403 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2445 ,  A61F2/2457 ,  A61F2/2466 ,  A61F2230/0069 ,  A61F2250/0059

摘要： Disclosed is a valve (502) for short time replacement, for taking over the function of and/or for temporary support of a native valve in a heart, the valve being positioned through the native valve upon implantation, the valve comprising an at least partially collapsible and/or at least partially expandable tube (602) and a flange (708). The valve allows for fast and easy replacement of a native valve, and more time for medical personnel to make decisions, prepare and/or perform surgery/medical intervention. Thus, the valve may provide for an improved quality of surgery/medical intervention.

摘要翻译： 公开了一种用于短时间更换的阀（502），用于接管心脏中的天然瓣膜的功能和/或临时支撑临时支撑阀，所述阀在植入时定位成穿过天然瓣膜，所述阀包括至少部分 可折叠和/或至少部分可扩张的管（602）和凸缘（708）。 该阀允许快速和容易地更换天然瓣膜，并且更多的时间让医务人员作出决定，准备和/或进行手术/医疗干预。 因此，瓣膜可提供改善的手术质量/医疗干预。

公开(公告)号：US20150265403A1

公开(公告)日：2015-09-24

申请号：US14441101

申请日：2013-11-06

申请人： MEDTENTIA INTERNATIONAL LTD OY

发明人： Olli Keränen

IPC分类号： A61F2/24 ,  B26F1/32

CPC分类号： A61F2/2427 ,  A61F2/2445 ,  A61F2/2448 ,  A61F2/2466 ,  A61F2230/0091 ,  A61F2240/001 ,  A61F2250/006 ,  B26F1/32

摘要： A medical device (1300) for holding an annuloplasty ring (101) is disclosed comprising a support (102) defining first and second peripheral edges (103, 126) each with a curvature about which said cardiac valve implant can be fitted, wherein the support comprises a grip section (128, 129) positioned between and connected with the first and second peripheral edges at opposite sides of the grip section, the grip section defining an opening for engagement with a gripper tool in use of the support, wherein said grip section is recessed inwards from either of said first and second peripheral edges thereby defining said opening between said support and said cardiac valve implant when held in place by said support. A method of manufacturing a medical device is disclosed.

摘要翻译： 公开了一种用于保持瓣膜成形术环（101）的医疗装置（1300），其包括限定第一和第二周边边缘（103,126）的支撑件（102），每个周边边缘具有可围绕所述心脏瓣膜植入物配合的曲率， 包括位于握持部分的相对侧之间并与第一和第二周边边缘连接的抓握部分（128,129），所述抓握部分限定用于使用所述支撑件与夹持器工具接合的开口，其中所述抓握部分 从所述第一和第二外围边缘中的任一个向内凹入，从而当由所述支撑件保持就位时，在所述支撑件和所述心脏瓣膜植入物之间限定所述开口。 公开了一种制造医疗装置的方法。

公开(公告)号：US09056009B2

公开(公告)日：2015-06-16

申请号：US13525093

申请日：2012-06-15

申请人： Olli Keränen

发明人： Olli Keränen

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2409 ,  A61F2/2448 ,  A61F2230/0091 ,  A61F2250/006

摘要： A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a first flange unit being connected to said first loop-shaped support. The flange unit is configured to be arranged against said annulus when said first loop-shaped support is abutting said heart valve.

摘要翻译： 用于改善心脏瓣膜功能的装置包括构造成邻接心脏瓣膜第一侧的第一环形支撑件和连接到所述第一环形支撑件的第一凸缘单元。 当所述第一环形支撑件邻接所述心脏瓣膜时，所述凸缘单元构造成抵靠所述环形物布置。

公开(公告)号：US11554014B2

公开(公告)日：2023-01-17

申请号：US16802484

申请日：2020-02-26

申请人： Medtentia International Ltd. Oy

发明人： Olli Keränen

IPC分类号： A61F2/24

摘要： A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a first flange unit being connected to said first loop-shaped support. The flange unit is configured to be arranged against said annulus when said first loop-shaped support is abutting said heart valve.

公开(公告)号：US20220323218A1

公开(公告)日：2022-10-13

申请号：US17849819

申请日：2022-06-27

申请人： Medtentia International Ltd Oy

发明人： Hans-Reinhard Zerkowski ,  Ger O'Carroll ,  Mark Pugh

IPC分类号： A61F2/24

摘要： A method for connecting an annuloplasty implant with a delivery and retrieval device includes retracting the annuloplasty implant towards a locking structure of the delivery and retrieval device with a retrieval element. The retrieval element connects the annuloplasty implant with the delivery and retrieval device when the annuloplasty implant is disconnected from the delivery and retrieval device. A complementary mating surface at an end portion of the annuloplasty implant is interlocked with a locking structure of the delivery and retrieval device. The complementary mating surface has a recess for locking longitudinal movement of the annuloplasty implant when it is received in the locking structure. The complementary mating surface has a first locking surface aligned in a first radial direction (R) to lock rotational movement of the annuloplasty implant, when received in the locking structure, around the longitudinal direction.