Fiber bragg grating temperature sensor

    公开(公告)号:US11029219B2

    公开(公告)日:2021-06-08

    申请号:US15542986

    申请日:2015-01-14

    Abstract: A temperature sensor and temperature sensing system for sensing changes in temperature up to a predetermined temperature is disclosed. The temperature sensor includes a microstructured optical fiber where the microstructured optical fiber includes a plurality of longitudinal channels extending along the microstructured optical fiber. The sensor also includes a fiber Bragg grating formed in the microstructured optical, fiber by generating a periodic modulation in the refractive index along a core region of the microstructured optical fiber. The fiber Bragg grating is operable to produce band reflection at a reflection wavelength that varies in accordance with changes in temperature at the core region of the optical fiber.

    T CELLS EXPRESSING CHEMOKINE RECEPTORS FOR TREATING CANCER

    公开(公告)号:US20200054677A1

    公开(公告)日:2020-02-20

    申请号:US16487323

    申请日:2018-02-21

    Abstract: The present disclosure relates to methods and products for preventing and/or treating cancer, and in particular to methods, cells and products for preventing and/or treating cancer using adoptive immunotherapies. In certain embodiments, the present disclosure provides a method of treating a subject suffering from, or susceptible to, a cancer associated with chemokine expressing cells, the method comprising exposing the subject to T cells expressing a receptor to the chemokine and thereby treating the subject.

    METHODS AND PRODUCTS FOR REDUCING ADHESIONS
    68.
    发明申请

    公开(公告)号:US20200038321A1

    公开(公告)日:2020-02-06

    申请号:US16489115

    申请日:2018-02-27

    Abstract: The present disclosure relates to methods and products for reducing adhesions. In certain embodiments, the present disclosure provides a method of reducing adhesions in a subject, the method comprising exposing a region in the subject susceptible to formation of an adhesion to an agent having iron chelation and/or antioxidant activity, thereby reducing adhesions in the subject.

    SYSTEM AND METHOD FOR GENERATING AN OPTICAL FREQUENCY STANDARD

    公开(公告)号:US20180329274A1

    公开(公告)日:2018-11-15

    申请号:US15741481

    申请日:2016-07-01

    Abstract: A system for generating an optical frequency standard is described. The system comprises a first laser source for generating a first laser output at a first frequency, a first second harmonic generator receiving as an input the first laser output to generate a frequency-doubled first laser output at a doubled first frequency, a second laser source for generating a second laser output at a second frequency different from the first frequency and a second harmonic generator receiving as an input the second laser output to form a frequency-doubled second laser output at a doubled second frequency. The system further includes a two-colour stabilisation arrangement to stabilise a sum of the doubled first and the doubled second frequencies that includes an interaction region incorporating a laser active material having a two-photon transition from a first energy level to a second energy level which receives as an input the frequency-doubled first laser output and the frequency-doubled second laser output where these outputs are selected to together cause the two-photon transition from the first energy level to the second energy level using an intermediate energy level to enhance the two-photon transition rate. The system also includes a detector to detect an indicator of the two-photon transition occurring in the interaction region which generates a frequency stabilisation signal for modifying either the first laser output or the second laser output to stabilise the sum of the doubled first frequency and the doubled second frequency to the two-photon transition based on the indicator and a stabilised optical output generator that includes a sum frequency generator receiving as an input the first laser output and the second laser output to generate a stabilised optical output with a frequency corresponding to the optical frequency standard.

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