公开(公告)号：US20030124635A1

公开(公告)日：2003-07-03

申请号：US10320691

申请日：2002-12-17

Applicant: Tokuyama Dental Corporation

Inventor： Fumio Ukaji ,  Kouichirou Hirata ,  Naohiro Hanyu ,  Kazuo Fukushima

IPC: G01N033/554 ,  G01N033/569 ,  C07K016/12

CPC classification number: G01N33/558 ,  C07K16/1275 ,  G01N33/56955 ,  G01N2333/315

Abstract: Streptococcus mutans in saliva or dental plaque collected from the oral cavity can be measured by the method of the present invention conveniently with high sensitivity without the performance of any complex procedure, such as culturing. The reactivity of the antibody of the present invention against Streptococcus mutans is 1000-fold or more greater than its reactivity against each of Streptococcus gordonii, Streptococcus salivarius, Streptococcus oralis, Streptococcus mitis, and Streptococcus sanguis.

Abstract translation: 通过口腔收集的唾液或牙菌斑变形链球菌可以通过本发明的方法以高灵敏度方便地测量，而不需要进行任何复杂的程序，如培养。 本发明的抗体对变形链球菌的反应性比其对戈链球菌，唾液链球菌，口服链球菌，链球菌和链球菌中的每一种的反应性大1000倍以上。

公开(公告)号：US12133778B2

公开(公告)日：2024-11-05

申请号：US17422504

申请日：2019-12-24

Applicant: TOKUYAMA DENTAL CORPORATION

Inventor： Ayumu Gyakushi ,  Tatsuya Yamazaki

IPC: A61C13/01 ,  A61C8/00 ,  C08L33/04

Abstract: A curable composition for a denture base is provided which comprises a paste-like composition containing (A) (meth)acrylic monomers, (B) a monomer-absorbing porous organic cross-linked polymer which can absorb the (A) (meth)acrylic monomers, and (C) a polymerization initiator selected from a photopolymerization initiator and a thermal polymerization initiator, wherein the content of (B) the monomer-absorbing porous organic cross-linked polymer is 20-80 parts by mass per 100 parts by mass of the (A) (meth)acrylic monomers, and the absorption amount: RAb={(g−A)/(g−B)}, measured in accordance with JIS K5101-13-1:2004, and defined by the amount of (A) (meth)acrylic monomers: g−A (unit: g) absorbed per unit amount of (B) the monomer-absorbing porous organic cross-linked polymer: g−B (unit: g) is greater than or equal to 1.5.

公开(公告)号：US11958970B2

公开(公告)日：2024-04-16

申请号：US17041045

申请日：2019-03-28

Applicant: Tokuyama Dental Corporation

Inventor： Takuma Matsuo ,  Hironobu Akizumi

IPC: C08L63/00 ,  A61C5/70 ,  A61C13/00 ,  A61C13/08 ,  A61C13/087 ,  A61K6/887 ,  A61K6/891 ,  C08K7/18 ,  C08L33/08 ,  C08L37/00

CPC classification number: C08L63/00 ,  A61C5/70 ,  A61C13/0003 ,  A61C13/0022 ,  A61C13/082 ,  A61C13/087 ,  A61K6/887 ,  A61K6/891 ,  C08K7/18 ,  C08L33/08 ,  C08L37/00 ,  C08K2201/005 ,  Y10T428/269

Abstract: A resin block suitable for dental cutting work may include a resin matrix (A) and spherical filler (B) whose average particle size ranges from 230 to 1000 nm. When 10 mm thick and measured with a colorimeter, the lightness (V) is less than 5.0 and the saturation (C) is less than 2.0 in a Munsell color system of colored light on a black background and a white background. When 1 mm thick, the lightness (V) is less than 5.0 and the saturation (C) is 0.05 or more on a black background, but on a white background, the lightness (V) is 6.0 or more and the saturation (C) is less than 2.0 for Munsell colored light. Resin blocks can be used for dental restoration such that dental prostheses produced from the block not using a pigment/dye are compatible with natural teeth color tone, and the color tone compatibility endures.

公开(公告)号：US20230310129A1

公开(公告)日：2023-10-05

申请号：US18331271

申请日：2023-06-08

Applicant: Tokuyama Dental Corporation

Inventor： Hiroshi MORISAKI ,  Naoto SHIOHIRA

IPC: A61C13/087 ,  A61C13/08 ,  A61C5/20

CPC classification number: A61C13/087 ,  A61C13/082 ,  A61C5/20

Abstract: A demonstration method can include demonstrating a feature of a dental composite resin, the feature being that the dental composite resin exhibits high color tone applicability to teeth of a wide range of shades. The demonstration of the feature can include: displaying a restoration process of obtaining a plurality of restoration samples by filling with the dental composite resin a cavity or a defect part of each artificial tooth of a plurality of artificial teeth and curing the dental composite resin; and displaying the plurality of restoration samples obtained by the restoration process.

公开(公告)号：US20230045524A1

公开(公告)日：2023-02-09

申请号：US17787823

申请日：2020-11-27

Applicant: TOKUYAMA DENTAL CORPORATION

Inventor： Hironobu Akizumi ,  Hiroshi Morisaki ,  Takuma Matsuo

IPC: A61K6/891 ,  A61K6/16 ,  A61K6/71

Abstract: Provided is a dental filling and repairing material kit that is for repairing a tooth having a cavity and that includes a first polymerization curable composition (A) for forming a surface exposed layer exposed to a surface after repairing and a second polymerization curable composition (B) for forming a foundation layer to serve as a foundation of the surface exposed layer. The first polymerization curable composition (A) is formed into a cured body that expresses a structure color by dispersion of inorganic spherical particles in a specific dispersion state in a matrix. Regarding the second polymerization curable composition (B), the brightness (V) of colored light when a sample of said composition with a thickness of 1 mm is measured by using a color difference meter under a black background, is not less than 5 in terms of a color measurement value in the Munsell color system.

公开(公告)号：US20220409349A1

公开(公告)日：2022-12-29

申请号：US17787594

申请日：2020-11-10

Applicant: TOKUYAMA DENTAL CORPORATION

Inventor： Shintaro YAMANE ,  Yuukou NAGASAWA

IPC: A61C13/00

Abstract: A holding surface is formed by an inclined surface formed from the upper edge of a flange of a disk-shaped processing block to a workpiece portion. The processing block is accommodated in an annular holding member, a pressing-side holding member is advanced with respect to an accommodating side holding member, and the facing peripheral edge of the pressing side holding member is brought into contact with the holding surface. Since the facing peripheral edge abuts on a circle centered around the axis of the holding surface formed by a conical side surface, the axis of the annular holding member and the axis of the processing block coincide with each other in a processing apparatus, and the processing block is set at a predetermined position

公开(公告)号：US20220127059A1

公开(公告)日：2022-04-28

申请号：US17423048

申请日：2019-12-19

Applicant: Tokuyama Dental Corporation

Inventor： Kazuhiko OKISHIO ,  Yasuhiro OGAWA

IPC: B65D81/32 ,  B65D75/58 ,  A61J1/10

Abstract: A composite liquid agent package containing a first pouch filled with a first liquid and a second pouch filled with a second liquid; and a kit for preparing a multicomponent composition, the kit including an outer bag housing the composite liquid agent package. With an opposite end section of the first pouch and an opposite end section of the second pouch being superposed, the superposed parts are heated and pressurized to exclude sealants, which are present within the opposite end sections, outwardly of the extremities of the outer layers of the opposite end sections, while heat-fusing the two extruded sealants together to join the two pouches.

公开(公告)号：US20210324178A1

公开(公告)日：2021-10-21

申请号：US17273225

申请日：2019-08-29

Applicant: TOKUYAMA DENTAL CORPORATION

Inventor： Takuma Matsuo ,  Hiroshi Morisaki ,  Hironobu Akizumi

IPC: C08K7/18 ,  A61K6/16 ,  A61K6/76 ,  A61K6/17 ,  A61K6/831 ,  A61K6/887 ,  C08K3/36 ,  C08F2/44 ,  C08F2/50 ,  C08F222/10

Abstract: Provided is a composite material which comprises a resin matrix and inorganic particles dispersed therein, wherein the inorganic particles comprise: one or more groups (G-PID) of spherical particles uniform in particle diameter which comprise aggregates of inorganic spherical particles having a specific average primary-particle diameter, have a narrow particle-size-distribution width, and have a lower refractive index than the resin matrix; and a group (G-SFP) of ultrafine particles. The inorganic spherical particles which constitute all the groups of spherical particles uniform in particle diameter contained in the resin matrix have an arrangement structure which is a short-range order structure satisfying a specific requirement. Also provided are a curable composition giving the composite material and a method for producing the curable composition.

公开(公告)号：US11098138B2

公开(公告)日：2021-08-24

申请号：US16078000

申请日：2017-03-08

Applicant: TOKUYAMA DENTAL CORPORATION

Inventor： Koji Furuhashi ,  Hironobu Akizumi

IPC: C08F2/46 ,  C08F2/50 ,  C08G61/04 ,  A61K6/62 ,  C08K3/22 ,  C08K3/36

Abstract: A photopolymerization initiator including (a) a photosensitizer, (b) a tertiary amine compound and (c) an aryliodonium salt wherein, as the aryliodonium salt (c), there is selected the one that generates an acid having a dissociation constant of not less than −3.0 in water of 25° C.

公开(公告)号：US11078303B2

公开(公告)日：2021-08-03

申请号：US16465018

申请日：2017-11-28

Applicant: TOKUYAMA DENTAL CORPORATION

Inventor： Hironobu Akizumi ,  Takuma Matsuo

IPC: A61K6/083 ,  C08F2/48 ,  C08K3/11 ,  C08F2/44 ,  C08F20/18 ,  C08K7/18 ,  A61K6/16 ,  A61K6/17 ,  A61K6/62 ,  A61K6/71 ,  A61K6/76 ,  A61K6/884 ,  A61K6/887

Abstract: Provided is a curable composition containing a polymerizable monomer (A), an organic-inorganic composite filler (B), and a polymerization initiator (C), wherein the organic-inorganic composite filler (B) includes an organic resin matrix (b1) and a spherical inorganic filler (b2) having an average primary particle size of 230-1000 nm, 90% or more of the number of individual particles constituting the spherical inorganic filler (b2) are present in a range of 5% greater or less than the average primary particle size, and the curable composition satisfies the following formulas (1) and (2): nP