公开(公告)号：US09879020B2

公开(公告)日：2018-01-30

申请号：US14429808

申请日：2013-09-20

Applicant: UWM Research Foundation, Inc. ,  The Trustees of Columbia University in the City of New York

Inventor： Douglas C. Stafford ,  James M. Cook ,  Alexander E. Arnold ,  Charles W. Emala ,  George Gallos ,  Michael Rajesh Stephen

IPC: C07D487/04 ,  C07D487/14 ,  C07D487/22

CPC classification number: C07D487/22 ,  C07D487/14

Abstract: Novel methods of treating inflammation and airway constriction using GABAergic compounds with reduced benzo-diazepine-like CNS activity are provided. Novel compounds which selectively target alpha-4 and alpha-5 GABAA receptors and methods of using those compounds to treat bronchoconstriction and inflammation are provided herein.

公开(公告)号：US20170271913A1

公开(公告)日：2017-09-21

申请号：US15076403

申请日：2016-03-21

Applicant: General Electric Company ,  UWM Research Foundation, Inc.

Inventor： Adel Nasiri ,  Seyed Ahmad Hamidi ,  Russell Wayne Hum ,  John Ferdinand Bopp

IPC: H02J9/06 ,  H02J7/00

CPC classification number: H02J9/061 ,  H02J7/0014 ,  H02J7/0021 ,  H02J7/0065

Abstract: A battery management system for monitoring battery cells of an uninterruptible power supply (UPS) coupled to a medical imaging load. The battery management system includes a first slave configured to obtain an operating parameter of a first battery cell. The first slave is configured to determine health of the first battery cell based at least in part on the operating parameter. The first slave is configured to generate a signal indicating the health of the first battery cell to communicate serially, via at least a second slave, to a master.

公开(公告)号：US09709526B2

公开(公告)日：2017-07-18

申请号：US14258160

申请日：2014-04-22

Applicant: UWM Research Foundation, Inc.

Inventor： David H. Petering ,  William J. Wobig ,  Andrew Nowakowski

IPC: G01N27/447 ,  C07K1/26

CPC classification number: G01N27/447 ,  C07K1/26 ,  G01N27/44747

Abstract: A method of characterizing proteins has been developed that includes providing a sample that contains a plurality of proteins to be characterized, wherein at least a first protein of the plurality of proteins is in its native form. Additionally, the method includes contacting the sample containing the plurality of proteins with a solution to form a sample solution, and then contacting the sample solution with a gel. The plurality of proteins is subsequently separated via electrophoresis within the gel, which includes an electrophoresis solution.

公开(公告)号：US09597342B2

公开(公告)日：2017-03-21

申请号：US14637334

申请日：2015-03-03

Applicant: UWM Research Foundation, Inc.

Inventor： James M. Cook ,  Terry S. Clayton ,  Hiteshkumar D. Jain ,  Yun Teng Johnson ,  Jie Yang ,  Sundari K. Rallipalli ,  Zhi-jian Wang ,  Ojas A. Namjoshi ,  Michael Ming-Jin Poe

IPC: A61K31/551 ,  C07D487/04 ,  A61K31/695 ,  C07D487/14 ,  C07D519/00

CPC classification number: A61K31/695 ,  A61K31/551 ,  C07D487/04 ,  C07D487/14 ,  C07D519/00

Abstract: Described herein are α3 or α2 or α2/α3 GABAergic receptor subtype selective ligands, pharmaceutical compositions, and methods of use of such ligands and compositions in treatment of anxiety disorders, epilepsy and schizophrenia with reduced sedative and ataxic side effects. In embodiments, such as α3 or α2 or α2/α3 GABAergic receptor subtype selective ligands lack ester linkages and may be thus relatively insensitive to hydrolysis by esterases.

公开(公告)号：US09554659B2

公开(公告)日：2017-01-31

申请号：US14060250

申请日：2013-10-22

Applicant: UWM Research Foundation, Inc.

Inventor： Jennifer J. Doering ,  Greg Krzecki

IPC: A47D9/00 ,  A47D7/04

CPC classification number: A47D9/00 ,  A47D7/04

Abstract: An infant sleep pod providing passive and/or active safety features. The infant sleep pod provides a safe sleeping environment for infants sharing sleep areas with adults. The infant sleep pod provides a firm, flat, separate, portable, and dedicated sleep space for an infant. The infant sleep pod includes a base with a bed and sidewall, and a bridge extending across the bed. The bridge covers a head portion of the bed, while a foot portion of the bed is left open for inserting and removing the infant. The bridge prevents pillows and blankets from covering the bed and infant. The infant sleep pod also includes electronics for monitoring the sleep pod. The electronics include a sensor unit in the bridge and a control unit in communication with the sensor unit. The control unit and sensor unit are operable to detect unsafe conditions and, in response, generate alerts.

Abstract translation: 婴儿睡眠荚提供被动和/或主动的安全特征。 婴儿睡眠荚为与成年人共享睡眠区域的婴儿提供安全的睡眠环境。 婴儿睡眠荚为婴儿提供坚实，平坦，独立，便携和专用的睡眠空间。 婴儿睡眠荚包括具有床和侧壁的基部，以及延伸穿过床的桥。 桥覆盖床的头部，而床的脚部保持打开以插入和移除婴儿。 桥梁防止枕头和毯子覆盖床和婴儿。 婴儿睡眠荚还包括用于监测睡眠荚的电子装置。 电子装置包括桥中的传感器单元和与传感器单元通信的控制单元。 控制单元和传感器单元可操作以检测不安全状况，并作为响应产生警报。

公开(公告)号：US09417294B2

公开(公告)日：2016-08-16

申请号：US14079889

申请日：2013-11-14

Applicant: UWM Research Foundation, Inc.

Inventor： Chiu Tai Law ,  Rani El-Hajjar

IPC: G01R33/032

CPC classification number: G01R33/0327 ,  G01R5/00

Abstract: A current sensor device. The current sensor device includes a strain distribution converter; an optical fiber coupled with the strain distribution converter; and a magnetostrictive material associated with the strain distribution converter such that a change in shape of the magnetostrictive material causes a change in length of the optical fiber.

Abstract translation: 电流传感器装置。 电流传感器装置包括应变分布转换器; 与应变分布转换器耦合的光纤; 以及与应变分布转换器相关联的磁致伸缩材料，使得磁致伸缩材料的形状变化导致光纤长度的变化。

公开(公告)号：US20150280229A1

公开(公告)日：2015-10-01

申请号：US14670022

申请日：2015-03-26

Applicant: UWM Research Foundation, Inc.

Inventor： Junhong Chen ,  Xingkang Huang

IPC: H01M4/38 ,  H01M10/0525 ,  H01M4/04 ,  H01M4/587

CPC classification number: H01M4/386 ,  H01M4/0428 ,  H01M4/587 ,  H01M10/052 ,  H01M10/0525 ,  H01M2004/021 ,  H01M2004/027

Abstract: The present disclosure relates generally to the field of lithium-ion batteries and battery modules. More specifically, the present disclosure relates to Si-based anode materials for use as anode active materials for lithium-ion batteries. One example includes micron/nano-scale structures that include a carbonate template structure and a silicon (Si) layer conformally deposited over the carbonate template. Another example includes a hollow, micron/nano-scale silicon structure having an oxygen content less than approximately 9%, wherein the interior of the hollow micron/nano-scale silicon structure is substantially free of carbon.

Abstract translation: 本公开一般涉及锂离子电池和电池模块的领域。 更具体地，本公开涉及用作锂离子电池的负极活性材料的Si基阳极材料。 一个实例包括微米/纳米级结构，其包括碳酸盐模板结构和在碳酸盐模板上共形沉积的硅（Si）层。 另一个实例包括具有小于约9％的氧含量的中空微米/纳米级硅结构，其中中空微米/纳米级硅结构的内部基本上不含碳。

公开(公告)号：US20150232473A1

公开(公告)日：2015-08-20

申请号：US14429808

申请日：2013-09-20

Applicant: UWM RESEARCH FOUNDATION, INC.

Inventor： Douglas C. Stafford ,  James M. Cook ,  Alexander E. Arnold ,  Charles W. Emala ,  George Gallos ,  Michael Rajesh Stephen

IPC: C07D487/22

CPC classification number: C07D487/22 ,  C07D487/14

Abstract: Novel methods of treating inflammation and airway constriction using GABAergic compounds with reduced benzo-diazepine-like CNS activity are provided. Novel compounds which selectively target alpha-4 and alpha-5 GABAA receptors and methods of using those compounds to treat bronchoconstriction and inflammation are provided herein.

Abstract translation: 提供了使用具有还原的苯并二氮杂类CNS活性的GABA能化合物治疗炎症和气道收缩的新方法。 本文提供了选择性靶向α-4和α-5 GABA A受体的新型化合物和使用这些化合物治疗支气管收缩和炎症的方法。

公开(公告)号：US20140132256A1

公开(公告)日：2014-05-15

申请号：US14079889

申请日：2013-11-14

Applicant: UWM Research Foundation, Inc.

Inventor： Chiu Tai Law ,  Rani El-Hajjar

IPC: G01R33/032

CPC classification number: G01R33/0327 ,  G01R5/00

Abstract: A current sensor device. The current sensor device includes a strain distribution converter; an optical fiber coupled with the strain distribution converter; and a magnetostrictive material associated with the strain distribution converter such that a change in shape of the magnetostrictive material causes a change in length of the optical fiber.

Abstract translation: 电流传感器装置。 电流传感器装置包括应变分布转换器; 与应变分布转换器耦合的光纤; 以及与应变分布转换器相关联的磁致伸缩材料，使得磁致伸缩材料的形状变化导致光纤长度的变化。

公开(公告)号：US20130344390A1

公开(公告)日：2013-12-26

申请号：US13916033

申请日：2013-06-12

Applicant: UWM Research Foundation, Inc.

Inventor： Junhong Chen ,  Marija Gajdardziska-Josifovska ,  Carol Hirschmugl ,  Eric Mattson ,  Haihui Pu ,  Michael Weinert

IPC: H01M10/0525 ,  G01N27/00 ,  H01M4/583 ,  C01B31/04 ,  C30B19/00

CPC classification number: H01M10/0525 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/23 ,  C30B7/00 ,  C30B29/02 ,  C30B29/60 ,  G01N27/127 ,  H01M4/583 ,  Y10S977/734 ,  Y10S977/892 ,  Y10S977/932 ,  Y10S977/948 ,  Y10S977/957

Abstract: A composition of graphene-based nanomaterials and a method of preparing the composition are provided. A carbon-based precursor is dissolved in water to form a precursor suspension. The precursor suspension is placed onto a substrate, thereby forming a precursor assembly. The precursor assembly is annealed, thereby forming the graphene-based nanomaterials. The graphene-based nanomaterials are crystallographically ordered at least in part and configured to form a plurality of diffraction rings when probed by an incident electron beam. In one aspect, the graphene-based nanomaterials are semiconducting. In one aspect, a method of engineering an energy bandgap of graphene monoxide generally includes providing at least one atomic layer of graphene monoxide having a first energy bandgap, and applying a substantially planar strain is applied to the graphene monoxide, thereby tuning the first energy band gap to a second energy bandgap.

Abstract translation: 提供了基于石墨烯的纳米材料的组合物和制备该组合物的方法。 将碳基前体溶于水中以形成前体悬浮液。 将前体悬浮液置于基材上，从而形成前体组合物。 将前体组件退火，从而形成基于石墨烯的纳米材料。 基于石墨烯的纳米材料至少部分地被晶体学排列，并且被构造成当被入射电子束探测时形成多个衍射环。 在一个方面，基于石墨烯的纳米材料是半导体的。 一方面，一种制备石墨烯一氧化碳的能带隙的方法通常包括提供具有第一能带隙的至少一个具有一氧化碳原子层的原子层，并且施加基本上平面的应变施加到一氧化碳上，由此调节第一能带 与第二能量带隙的差距。