公开(公告)号：US20200338032A1

公开(公告)日：2020-10-29

申请号：US16757312

申请日：2018-10-16

Applicant: AVALON FLAVIVIRAL THERAPEUTICS (HK) LIMITED ,  VERSITECH LIMITED

Inventor： Shuofeng YUAN ,  Fuk Woo Jasper CHAN ,  Hin CHU ,  Johnson Yiu-Nam LAU ,  Kwok Yung YUEN

IPC: A61K31/192

Abstract: AM580 and structurally related compounds have been found to be useful in treating infection by a wide range of RNA and DNA viruses, and also in reducing associated inflammation. This activity is independent of RAR-α signaling, and is not a result of activation of the hosts innate immune response. Broad antiviral activity of AM580 and structurally related compounds is a due to modulation of lipogenesis so as to correct disregulation of this pathway in virus-infected cells, via inhibition of nSREPBP

公开(公告)号：US10742954B2

公开(公告)日：2020-08-11

申请号：US15748503

申请日：2016-08-01

Applicant: VERSITECH LIMITED

Inventor： Shing Chow Chan ,  Ho Chun Wu

IPC: H04N13/128 ,  H04N21/488 ,  H04N13/111 ,  H04N13/161 ,  H04N13/00

Abstract: A technique for displaying 3D videos creates a representation of image deformation, such as depth maps, in terms of a function for overlaying kernels with variable support and order. By optimizing the kernel type, order and support, which are allowed to be varied across different region of the deformation, it is able to approximate the image deformations in terms of the kernel parameters. Since the number of kernel parameters is usually much smaller than that of the number of pixels, this allows a significant reduction in the storage size of the image deformation.

公开(公告)号：US10713805B2

公开(公告)日：2020-07-14

申请号：US15748532

申请日：2016-08-01

Applicant: VERSITECH LIMITED

Inventor： Shing Chow Chan ,  Jia-fei Wu

IPC: H04N19/122 ,  H04N19/11 ,  H04N19/82 ,  G06T7/593 ,  H04N19/59 ,  H04N19/136 ,  H04N13/00 ,  H04N13/128 ,  H04N13/161

Abstract: A method for encoding depth map image involves dividing the image into blocks. These blocks are then classified into smooth blocks without large depth discontinuities and discontinuous blocks with large depth discontinuities. In the discontinuous blocks, depth discontinuities are represented by line segments and partitions. Interpolation-based intra prediction is used to approximate and compress the depth values in the smooth blocks and partitions. Further compression can be achieved with of depth-aware quantization, adaptive de-blocking filtering, scale adaptive block size, and resolution decimation schemes.

公开(公告)号：US20200182790A1

公开(公告)日：2020-06-11

申请号：US16618536

申请日：2018-06-01

Applicant: VERSITECH LIMITED

Inventor： Wendi LI ,  Zhouyang ZHU ,  Shijie LI

IPC: G01N21/552 ,  B82Y15/00

Abstract: A plasmonic sensor with gradient nanostructures and a method of use thereof is provided. The gradient of shapes will induce different spectral responses at different region of the sensor and show different colors. When there is a change in the environment properties of a substance, such as refractive index, gas concentration or ion density changes, the sensor displays different images, e.g., redial intensity displays and radial color displays. An image recognition based method can be used to extract the environment property with high accuracy according to the sensor image.

公开(公告)号：US20200163957A1

公开(公告)日：2020-05-28

申请号：US16776403

申请日：2020-01-29

Applicant: EMV Enhance (HK) Limited ,  VERSITECH LIMITED

Inventor： Fan Ngai HUNG ,  Jinxia ZHANG ,  Kai Wang Kelvin TO ,  Johnson Yiu-Nam LAU ,  Kwok Yung YUEN

IPC: A61K31/4745 ,  A61K39/145 ,  A61K9/00 ,  C07K16/10 ,  A61K39/39 ,  A61P31/16 ,  A61K39/12 ,  A61K45/06

Abstract: Compositions and methods are described in which the topical application of a toll-like receptor 7 agonist or a toll-like receptor 9 agonist at or near a subdermal vaccination site provides an enhanced response to the vaccination. The enhanced response can be an elevated antibody titer relative to an untreated but vaccinated subject, and/or development of cross-species immunity to species not present in the vaccinating composition.

公开(公告)号：US20200010506A1

公开(公告)日：2020-01-09

申请号：US16310364

申请日：2017-03-24

Applicant: Versitech Limited

Inventor： Xuechen Li ,  Hoi Yee Chow

IPC: C07K7/08 ,  A61P31/04

Abstract: Cyclic lipopeptides having one or more modifications relative to daptomycin, and methods of making them are provided. The cyclic lipopeptides can be used as antibacterial agents. The daptomycin analogues are generated by chemical synthesis, which makes introduction of an unnatural amino acid and any modification into daptomycin possible. Pharmaceutical compositions and method of use thereof for the disclosed daptomycin analogues are also provided.

公开(公告)号：US20190273903A1

公开(公告)日：2019-09-05

申请号：US15748503

申请日：2016-08-01

Applicant: VERSITECH LIMITED

Inventor： Shing Chow CHAN ,  Ho Chun WU

IPC: H04N13/161 ,  H04N13/128 ,  H04N21/488

Abstract: A technique for displaying 3D videos creates a representation of image deformation, such as depth maps, in terms of a function for overlaying kernels with variable support and order. By optimizing the kernel type, order and support, which are allowed to be varied across different region of the deformation, it is able to approximate the image deformations in terms of the kernel parameters. Since the number of kernel parameters is usually much smaller than that of the number of pixels, this allows a significant reduction in the storage size of the image deformation.

公开(公告)号：US10335113B2

公开(公告)日：2019-07-02

申请号：US15445582

申请日：2017-02-28

Applicant: VERSITECH LIMITED

Inventor： Alfred Cheuk Hang Yu ,  Yat Shun Yiu

IPC: A61B8/00 ,  A61B8/06 ,  A61B8/08 ,  A61B8/02 ,  G01S15/89 ,  G01S7/52 ,  G01S15/58 ,  G06T7/20 ,  A61B8/12

Abstract: Apparatus and methods of use are provided for complex flow imaging and analysis that is non-invasive, accurate, and time-resolved. It is particularly useful in imaging of vascular flow with spatiotemporal fluctuations. This apparatus is an ultrasound-based framework called vector projectile imaging (VPI) that can dynamically render complex flow patterns over an imaging view at millisecond time resolution. The VPI apparatus and methods comprise: (i) high-frame-rate broad-view data acquisition (based on steered plane wave firings); (ii) flow vector estimation derived from multi-angle Doppler analysis (coupled with data regularization and least-squares fitting); and (iii) dynamic visualization of color-encoded vector projectiles (with flow speckles displayed as adjunct).

公开(公告)号：US20190133907A1

公开(公告)日：2019-05-09

申请号：US16095616

申请日：2016-04-21

Applicant: Versitech Limited

Inventor： Mingfu Wang ,  Shu Ting Hu ,  Yi Zhen Wu

IPC: A61K8/49 ,  A61K31/353 ,  A61Q19/02 ,  A61P17/00

Abstract: The composition includes a cyclic, unsaturated compound, preferably a polyphenol derivative. It reduces the synthesis of melanin by inhibiting the activity and expression levels of tyrosinase and related proteins, thereby preventing and limiting the content and distribution of melanin in mammalian skin. It also induces autophagy of melanosome, thereby restricting the synthesis, storage and transfer of melanin from melanocyte to keratinocyte. The dual modes of action allow for the efficacy of the composition at low dosage without causing toxicity to lighten skin and treat disorders associated with hyperpigmentation.

公开(公告)号：US10250072B2

公开(公告)日：2019-04-02

申请号：US13975409

申请日：2013-08-26

Applicant: Versitech Limited

Inventor： Wai Man Ng ,  Cheng Zhang ,  Deyan Lin ,  Ron Shu Yeun Hui

IPC: H01F27/42 ,  H01F38/00 ,  H01F37/00 ,  H02J50/12 ,  H02J5/00 ,  H02J7/02 ,  H02J17/00 ,  H02J50/40

Abstract: The present invention provides a wireless power transmitter comprising at least two loops, and separate drivers, each driving a respective one of the loops and providing a respective alternating current to the respective loop, thereby to transmit wireless power for receipt by at least one wireless power receiver. Also provided is a wireless power receiver comprising a receiver loop, and at least two focusing loops. An associated system and an associated method are also provided.