公开(公告)号：US10576029B2

公开(公告)日：2020-03-03

申请号：US15630988

申请日：2017-06-23

Applicant: Colgate-Palmolive Company

Inventor： Aarti Rege ,  Michael Prencipe

IPC: A61K8/27 ,  A61K8/81 ,  A61K6/00 ,  A61K8/21 ,  A61K8/24 ,  A61Q11/00

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.

公开(公告)号：US10406087B2

公开(公告)日：2019-09-10

申请号：US16212129

申请日：2018-12-06

Applicant: Colgate-Palmolive Company

Inventor： Aarti Rege ,  Michael Prencipe ,  Marc Estriplet

IPC: A61K8/44 ,  A61K8/21 ,  A61K8/27 ,  A61K8/365 ,  A61K8/24 ,  A61Q11/00 ,  A61K8/362

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.

公开(公告)号：US10391044B2

公开(公告)日：2019-08-27

申请号：US15570430

申请日：2015-05-01

Applicant: Colgate-Palmolive Company

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/24 ,  A61K8/27 ,  A61K8/36 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/19

Abstract: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a stannous ion source, a polyphosphate and an acid in a calcium pyrophosphate base. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.

公开(公告)号：US20190142716A1

公开(公告)日：2019-05-16

申请号：US16246821

申请日：2019-01-14

Applicant: Colgate-Palmolive Company

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/19 ,  A61K8/24 ,  A61K8/21 ,  A61K8/81 ,  A61K8/27 ,  A61K8/73 ,  A61Q11/00

Abstract: An oral care composition containing a stannous ion source, a zinc ion source, a polyphosphate, and a thickening agent. The thickening agent contains polyvinylpyrrolidone, a polysaccharide gum and carboxymethyl cellulose. The compositions have excellent rheology properties.

公开(公告)号：US20180296453A1

公开(公告)日：2018-10-18

申请号：US16013594

申请日：2018-06-20

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Diane CUMMINS ,  Ravi SUBRAMANYAM ,  Richard SULLIVAN ,  Ralph Peter SANTARPIA III ,  Sarita Vera MELLO ,  Lynette ZAIDEL ,  Suman CHOPRA ,  Qin WANG ,  Gary TAMBS ,  Virginia Monsul BARNES ,  Donghui WU ,  Andre MORGAN ,  Rajnish KOHLI ,  Richard ROBINSON ,  Sergio LEITE ,  Eric SIMON

IPC: A61K8/44 ,  A61Q11/00 ,  A61K31/198 ,  A61K8/19 ,  A61K8/24 ,  A61K8/21

Abstract: This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an anionic surfactant, and to methods of using and of making such compositions.

公开(公告)号：US20180168963A1

公开(公告)日：2018-06-21

申请号：US15674781

申请日：2017-08-11

Applicant: Colgate-Palmolive Company

Inventor： Aarti Rege ,  Michael Prencipe

IPC: A61K8/27 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/44 ,  A61K8/24 ,  A61K8/365

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, an anionic polymer, and a basic amino acid, as well as methods of using the same.

公开(公告)号：US09895304B2

公开(公告)日：2018-02-20

申请号：US15344504

申请日：2016-11-04

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Lynette A. Zaidel ,  Guisheng Pan ,  Suman K. Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

IPC: A61Q11/02 ,  A61K8/81 ,  A61K8/02 ,  A61K8/22 ,  A61Q11/00 ,  A61K8/24 ,  A61K8/90 ,  A61K8/49 ,  A61K8/891

CPC classification number: A61K8/8176 ,  A61K8/0208 ,  A61K8/22 ,  A61K8/24 ,  A61K8/49 ,  A61K8/817 ,  A61K8/891 ,  A61K8/90 ,  A61K2800/805 ,  A61Q11/00 ,  A61Q11/02

Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

公开(公告)号：US09889077B2

公开(公告)日：2018-02-13

申请号：US14527829

申请日：2014-10-30

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Lyndsay Schaeffer-Korbylo ,  Andre Michelle Morgan ,  Davide Miksa ,  Laurence Du-Thumm ,  Michael Prencipe ,  Evangelia Arvanitidou ,  Gregory Szewczyk

IPC: A61Q11/00 ,  A61K8/97 ,  A61K8/27 ,  A61K8/34 ,  A01N49/00 ,  A61K8/35 ,  A61K8/33 ,  A61K8/49 ,  A61K8/365 ,  A61K8/19 ,  A61K8/21

CPC classification number: A61K8/34 ,  A01N49/00 ,  A61K8/19 ,  A61K8/21 ,  A61K8/33 ,  A61K8/342 ,  A61K8/347 ,  A61K8/35 ,  A61K8/365 ,  A61K8/4926 ,  A61K8/97 ,  A61K2800/92 ,  A61Q11/00 ,  A01N31/08 ,  A01N31/16 ,  A01N43/40 ,  A01N59/16 ,  A01N65/00 ,  A01N2300/00 ,  A01N65/08

Abstract: Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.

公开(公告)号：US09883995B2

公开(公告)日：2018-02-06

申请号：US15365889

申请日：2016-11-30

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Michael Prencipe ,  Andre Morgan ,  Venda Porter Maloney

IPC: A61K8/27 ,  A61Q11/00 ,  A61K8/02 ,  A61K8/44 ,  A61K8/73

CPC classification number: A61K8/27 ,  A61K8/0245 ,  A61K8/19 ,  A61K8/29 ,  A61K8/44 ,  A61K8/731 ,  A61K2800/412 ,  A61K2800/5922 ,  A61K2800/594 ,  A61K2800/624 ,  A61Q11/00

Abstract: Disclosed are oral care compositions, for example dentifrice compositions, comprising an oral care composition comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and at least one amino acid capable of chelating the metal oxide. The composition may comprise a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.

公开(公告)号：US09814666B2

公开(公告)日：2017-11-14

申请号：US15106543

申请日：2013-12-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Michael Prencipe ,  Suzanne Jogun ,  Xiang Chen

IPC: A61K8/81 ,  A61K8/25 ,  A61Q11/00 ,  C08L43/02 ,  A61K8/27 ,  A61K8/34 ,  A61K8/49

CPC classification number: A61K8/8152 ,  A61K8/25 ,  A61K8/27 ,  A61K8/345 ,  A61K8/347 ,  A61K8/4926 ,  A61K8/8164 ,  A61K2800/28 ,  A61K2800/5424 ,  A61K2800/92 ,  A61Q11/00 ,  C08L43/02 ,  C08L33/02

Abstract: Provided is an oral care composition comprising a phosphate/acrylate co-polymer, a synthetic anionic linear polycarboxylate polymer, and an orally acceptable carrier; and methods of using the same.